产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
亮紫色785™抗小鼠/人类CD44
目录 :
103059
规格 :
50微克
价格 :
273美元
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
亮紫色785
克隆名称 :
IM7
反应物种 :
人类, 小鼠,
应用 :
免疫组化, 免疫细胞化学, 流式细胞仪, 免疫组化-自由浮动切片
更多信息或购买 :
文章摘录数: 77
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 图 2b
Quách T, Huang W, Sahu R, Diadhiou C, Raparia C, Johnson R, et al. Context-dependent induction of autoimmunity by TNF signaling deficiency. JCI Insight. 2022;7: pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 1:1000; 图 2f
Wei J, Mattapallil M, Horai R, Jittayasothorn Y, Modi A, Sen H, et al. A novel role for lipoxin A4 in driving a lymph node-eye axis that controls autoimmunity to the neuroretina. elife. 2020;9: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3a, 5a, 6a, s4b
Nelson C, Thompson E, Quarnstrom C, Fraser K, Seelig D, Bhela S, et al. Robust Iterative Stimulation with Self-Antigens Overcomes CD8+ T Cell Tolerance to Self- and Tumor Antigens. Cell Rep. 2019;28:3092-3104.e5 pubmed 出版商
  • 流式细胞仪; 猫; 图 1e
  • 流式细胞仪; 人类; 图 1f
Clark K, Fierro F, Ko E, Walker N, Arzi B, Tepper C, et al. Human and feline adipose-derived mesenchymal stem cells have comparable phenotype, immunomodulatory functions, and transcriptome. Stem Cell Res Ther. 2017;8:69 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4b
Ramos G, van den Berg A, Nunes Silva V, Weirather J, Peters L, Burkard M, et al. Myocardial aging as a T-cell-mediated phenomenon. Proc Natl Acad Sci U S A. 2017;114:E2420-E2429 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2a
Wei Y, Lu C, Chen J, Cui G, Wang L, Yu T, et al. High salt diet stimulates gut Th17 response and exacerbates TNBS-induced colitis in mice. Oncotarget. 2017;8:70-82 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100; 图 2b
Morita K, Okamura T, Inoue M, Komai T, Teruya S, Iwasaki Y, et al. Egr2 and Egr3 in regulatory T cells cooperatively control systemic autoimmunity through Ltbp3-mediated TGF-β3 production. Proc Natl Acad Sci U S A. 2016;113:E8131-E8140 pubmed
  • 流式细胞仪; 小鼠
Cecchinato V, Bernasconi E, Speck R, Proietti M, Sauermann U, D Agostino G, et al. Impairment of CCR6+ and CXCR3+ Th Cell Migration in HIV-1 Infection Is Rescued by Modulating Actin Polymerization. J Immunol. 2017;198:184-195 pubmed
  • 流式细胞仪; 小鼠; 1:200; 图 6c
Hirako I, Ataide M, Faustino L, Assis P, Sorensen E, Ueta H, et al. Splenic differentiation and emergence of CCR5+CXCL9+CXCL10+ monocyte-derived dendritic cells in the brain during cerebral malaria. Nat Commun. 2016;7:13277 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 6f
Serr I, Fürst R, Ott V, Scherm M, Nikolaev A, Gökmen F, et al. miRNA92a targets KLF2 and the phosphatase PTEN signaling to promote human T follicular helper precursors in T1D islet autoimmunity. Proc Natl Acad Sci U S A. 2016;113:E6659-E6668 pubmed
  • 流式细胞仪; 小鼠; 1:800; 图 5e
Starobinets H, Ye J, Broz M, Barry K, Goldsmith J, Marsh T, et al. Antitumor adaptive immunity remains intact following inhibition of autophagy and antimalarial treatment. J Clin Invest. 2016;126:4417-4429 pubmed 出版商
  • 免疫细胞化学; 人类; 图 3g
Jung Y, Riven I, Feigelson S, Kartvelishvily E, Tohya K, Miyasaka M, et al. Three-dimensional localization of T-cell receptors in relation to microvilli using a combination of superresolution microscopies. Proc Natl Acad Sci U S A. 2016;113:E5916-E5924 pubmed
  • 流式细胞仪; 小鼠; 图 S1
Uhde A, Herder V, Akram Khan M, Ciurkiewicz M, Schaudien D, Teich R, et al. Viral Infection of the Central Nervous System Exacerbates Interleukin-10 Receptor Deficiency-Mediated Colitis in SJL Mice. PLoS ONE. 2016;11:e0161883 pubmed 出版商
  • 流式细胞仪; 人类; 图 4
Di Scala M, Otano I, Gil Farina I, Vanrell L, Hommel M, Olague C, et al. Complementary Effects of Interleukin-15 and Alpha Interferon Induce Immunity in Hepatitis B Virus Transgenic Mice. J Virol. 2016;90:8563-74 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:300; 图 4f
Riedel A, Shorthouse D, Haas L, Hall B, Shields J. Tumor-induced stromal reprogramming drives lymph node transformation. Nat Immunol. 2016;17:1118-27 pubmed 出版商
  • 免疫组化; 人类; 图 1a
  • 免疫组化; 小鼠; 图 1a
Nasri I, Bonnet D, Zwarycz B, d Aldebert E, Khou S, Mezghani Jarraya R, et al. PAR2-dependent activation of GSK3? regulates the survival of colon stem/progenitor cells. Am J Physiol Gastrointest Liver Physiol. 2016;311:G221-36 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 6
Goetz B, An W, Mohapatra B, Zutshi N, Iseka F, Storck M, et al. A novel CBL-Bflox/flox mouse model allows tissue-selective fully conditional CBL/CBL-B double-knockout: CD4-Cre mediated CBL/CBL-B deletion occurs in both T-cells and hematopoietic stem cells. Oncotarget. 2016;7:51107-51123 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2c
Contreras F, Prado C, Gonzalez H, Franz D, Osorio Barrios F, Osorio F, et al. Dopamine Receptor D3 Signaling on CD4+ T Cells Favors Th1- and Th17-Mediated Immunity. J Immunol. 2016;196:4143-9 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 6
Nieves W, Hung L, Oniskey T, Boon L, Foretz M, Viollet B, et al. Myeloid-Restricted AMPK?1 Promotes Host Immunity and Protects against IL-12/23p40-Dependent Lung Injury during Hookworm Infection. J Immunol. 2016;196:4632-40 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5
Rialdi A, Campisi L, Zhao N, Lagda A, Pietzsch C, Ho J, et al. Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation. Science. 2016;352:aad7993 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:200; 图 1b
O Leary C, Riling C, Spruce L, Ding H, Kumar S, Deng G, et al. Ndfip-mediated degradation of Jak1 tunes cytokine signalling to limit expansion of CD4+ effector T cells. Nat Commun. 2016;7:11226 pubmed 出版商
  • 流式细胞仪; 小鼠
Mall C, Sckisel G, Proia D, Mirsoian A, Grossenbacher S, Pai C, et al. Repeated PD-1/PD-L1 monoclonal antibody administration induces fatal xenogeneic hypersensitivity reactions in a murine model of breast cancer. Oncoimmunology. 2016;5:e1075114 pubmed
  • 流式细胞仪; 小鼠; 图 2
Apostolidis S, Rodríguez Rodríguez N, Suárez Fueyo A, Dioufa N, Ozcan E, Crispín J, et al. Phosphatase PP2A is requisite for the function of regulatory T cells. Nat Immunol. 2016;17:556-64 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2b
Flach A, Litke T, Strauss J, Haberl M, Gómez C, Reindl M, et al. Autoantibody-boosted T-cell reactivation in the target organ triggers manifestation of autoimmune CNS disease. Proc Natl Acad Sci U S A. 2016;113:3323-8 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 6s
Haribhai D, Ziegelbauer J, Jia S, Upchurch K, Yan K, Schmitt E, et al. Alternatively Activated Macrophages Boost Induced Regulatory T and Th17 Cell Responses during Immunotherapy for Colitis. J Immunol. 2016;196:3305-17 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
Pelly V, Kannan Y, Coomes S, Entwistle L, Rückerl D, Seddon B, et al. IL-4-producing ILC2s are required for the differentiation of TH2 cells following Heligmosomoides polygyrus infection. Mucosal Immunol. 2016;9:1407-1417 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5a
Roffê E, Marino A, Weaver J, Wan W, de Araújo F, Hoffman V, et al. Trypanosoma cruzi Causes Paralyzing Systemic Necrotizing Vasculitis Driven by Pathogen-Specific Type I Immunity in Mice. Infect Immun. 2016;84:1123-1136 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s5
Catarinella M, Monestiroli A, Escobar G, Fiocchi A, Tran N, Aiolfi R, et al. IFNα gene/cell therapy curbs colorectal cancer colonization of the liver by acting on the hepatic microenvironment. EMBO Mol Med. 2016;8:155-70 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5
MikyÅ¡ková R, Å tÄ›pánek I, Indrová M, Bieblová J, Šímová J, Truxová I, et al. Dendritic cells pulsed with tumor cells killed by high hydrostatic pressure induce strong immune responses and display therapeutic effects both in murine TC-1 and TRAMP-C2 tumors when combined with docetaxel chemotherapy. Int J Oncol. 2016;48:953-64 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
Adachi T, Kobayashi T, Sugihara E, Yamada T, Ikuta K, Pittaluga S, et al. Hair follicle-derived IL-7 and IL-15 mediate skin-resident memory T cell homeostasis and lymphoma. Nat Med. 2015;21:1272-9 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1b
Wu V, Smith A, You H, Nguyen T, Ferguson R, Taylor M, et al. Plasmacytoid dendritic cell-derived IFNα modulates Th17 differentiation during early Bordetella pertussis infection in mice. Mucosal Immunol. 2016;9:777-86 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1d
Vlachou K, Mintzas K, Glymenaki M, Ioannou M, Papadaki G, Bertsias G, et al. Elimination of Granulocytic Myeloid-Derived Suppressor Cells in Lupus-Prone Mice Linked to Reactive Oxygen Species-Dependent Extracellular Trap Formation. Arthritis Rheumatol. 2016;68:449-61 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s7
McCormack R, de Armas L, Shiratsuchi M, Fiorentino D, Olsson M, Lichtenheld M, et al. Perforin-2 is essential for intracellular defense of parenchymal cells and phagocytes against pathogenic bacteria. elife. 2015;4: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3f
Martin Blondel G, Pignolet B, Tietz S, Yshii L, Gebauer C, Périnat T, et al. Migration of encephalitogenic CD8 T cells into the central nervous system is dependent on the α4β1-integrin. Eur J Immunol. 2015;45:3302-12 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3a
Ngiow S, Young A, Jacquelot N, Yamazaki T, Enot D, Zitvogel L, et al. A Threshold Level of Intratumor CD8+ T-cell PD1 Expression Dictates Therapeutic Response to Anti-PD1. Cancer Res. 2015;75:3800-11 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 7
McCully M, Collins P, Hughes T, Thomas C, Billen J, O Donnell V, et al. Skin Metabolites Define a New Paradigm in the Localization of Skin Tropic Memory T Cells. J Immunol. 2015;195:96-104 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2
Pei B, Zhao M, Miller B, Véla J, Bruinsma M, Virgin H, et al. Invariant NKT cells require autophagy to coordinate proliferation and survival signals during differentiation. J Immunol. 2015;194:5872-84 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
Wiesner D, Specht C, Lee C, Smith K, Mukaremera L, Lee S, et al. Chitin recognition via chitotriosidase promotes pathologic type-2 helper T cell responses to cryptococcal infection. PLoS Pathog. 2015;11:e1004701 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
Huang Y, Clarke F, Karimi M, Roy N, Williamson E, Okumura M, et al. CRK proteins selectively regulate T cell migration into inflamed tissues. J Clin Invest. 2015;125:1019-32 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2
Cabrera Perez J, Condotta S, James B, Kashem S, Brincks E, Rai D, et al. Alterations in antigen-specific naive CD4 T cell precursors after sepsis impairs their responsiveness to pathogen challenge. J Immunol. 2015;194:1609-20 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
Nguyen L, Pan J, Dinh T, Hadeiba H, O Hara E, Ebtikar A, et al. Role and species-specific expression of colon T cell homing receptor GPR15 in colitis. Nat Immunol. 2015;16:207-213 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s2
Skripuletz T, Manzel A, Gropengießer K, Schäfer N, Gudi V, Singh V, et al. Pivotal role of choline metabolites in remyelination. Brain. 2015;138:398-413 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1
  • 免疫组化; 人类; 图 2
Senturk S, Yao Z, Camiolo M, Stiles B, Rathod T, Walsh A, et al. p53? is a transcriptionally inactive p53 isoform able to reprogram cells toward a metastatic-like state. Proc Natl Acad Sci U S A. 2014;111:E3287-96 pubmed 出版商
  • 免疫细胞化学; 人类; 1:200; 图 st13
Hwang W, Jiang J, Yang S, Huang T, Lan H, Teng H, et al. MicroRNA-146a directs the symmetric division of Snail-dominant colorectal cancer stem cells. Nat Cell Biol. 2014;16:268-80 pubmed 出版商
Sun X, Wu B, Chiang H, Deng H, Zhang X, Xiong W, et al. Tumour DDR1 promotes collagen fibre alignment to instigate immune exclusion. Nature. 2021;599:673-678 pubmed 出版商
McLane L, Ngiow S, Chen Z, Attanasio J, Manne S, Ruthel G, et al. Role of nuclear localization in the regulation and function of T-bet and Eomes in exhausted CD8 T cells. Cell Rep. 2021;35:109120 pubmed 出版商
Chen Z, Arai E, Khan O, Zhang Z, Ngiow S, He Y, et al. In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer. Cell. 2021;184:1262-1280.e22 pubmed 出版商
Montel Hagen A, Sun V, Casero D, Tsai S, Zampieri A, Jackson N, et al. In Vitro Recapitulation of Murine Thymopoiesis from Single Hematopoietic Stem Cells. Cell Rep. 2020;33:108320 pubmed 出版商
Laczkó D, Hogan M, Toulmin S, Hicks P, Lederer K, Gaudette B, et al. A Single Immunization with Nucleoside-Modified mRNA Vaccines Elicits Strong Cellular and Humoral Immune Responses against SARS-CoV-2 in Mice. Immunity. 2020;53:724-732.e7 pubmed 出版商
Lebel M, Coutelier M, Galipeau M, Kleinman C, Moon J, Melichar H. Differential expression of tissue-restricted antigens among mTEC is associated with distinct autoreactive T cell fates. Nat Commun. 2020;11:3734 pubmed 出版商
Gurusamy D, Henning A, Yamamoto T, Yu Z, Zacharakis N, Krishna S, et al. Multi-phenotype CRISPR-Cas9 Screen Identifies p38 Kinase as a Target for Adoptive Immunotherapies. Cancer Cell. 2020;37:818-833.e9 pubmed 出版商
Wen J, Wang Y, Valentine K, Dos Santos Alves R, Xu Z, Regla Nava J, et al. CD4+ T Cells Cross-Reactive with Dengue and Zika Viruses Protect against Zika Virus Infection. Cell Rep. 2020;31:107566 pubmed 出版商
Pustlauk W, Westhoff T, Claeys L, Roch T, Geisler S, Babel N. Induced osteogenic differentiation of human smooth muscle cells as a model of vascular calcification. Sci Rep. 2020;10:5951 pubmed 出版商
Wu B, Sun X, Yuan B, Ge F, Gupta H, Chiang H, et al. PPARγ inhibition boosts efficacy of PD-L1 Checkpoint Blockade Immunotherapy against Murine Melanoma in a sexually dimorphic manner. Int J Biol Sci. 2020;16:1526-1535 pubmed 出版商
Pham T, Brewer S, Thurston T, Massis L, Honeycutt J, Lugo K, et al. Salmonella-Driven Polarization of Granuloma Macrophages Antagonizes TNF-Mediated Pathogen Restriction during Persistent Infection. Cell Host Microbe. 2020;27:54-67.e5 pubmed 出版商
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Elong Ngono A, Shresta S. Cross-Reactive T Cell Immunity to Dengue and Zika Viruses: New Insights Into Vaccine Development. Front Immunol. 2019;10:1316 pubmed 出版商
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产品信息
抗原 :
CD44
Apps. Abbrev. :
流式细胞仪
目录 :
103059
克隆 :
IM7
产品 :
亮紫色785™抗小鼠/人类CD44
抗体亚型 :
Rat IgG2b, κ
其他名称 :
Hermes, Pgp-1, H-CAM, HUTCH-1, ECMR III, gp85, Ly-24
规格 :
50微克
价格(美元) :
273美元
反应物种 :
小鼠, 人类
克隆性 :
单克隆
宿主 :
大鼠
共轭标签/标签/标记 :
BV785
免疫原 :
Dexamethasone-induced myeloid leukemia M1 cells
应用注释 :
Clone IM7 has been reported to recognize an epitope common to alloantigens and all isoforms of CD44 17,18 that is located between amino acids 145 and 186 20 . This clone has been verified for immunocytochemistry (ICC) and frozen immunohistochemistry (IHC-F). Additional reported applications (for the relevant formats) include: immunohistochemistry of acetone-fixed frozen sections and formalin-fixed paraffin-embedded sections 6,7 , complement-mediated cytotoxicity 1 , immunoprecipitation 1,3 , in vivo inhibition of DTH 4,5 , and spatial biology (IBEX) 23,24 . The Ultra-LEAF purified antibody (Endotoxin 0.01 EU/ug, Azide-Free, 0.2 um filtered) is recommended for functional assays (Cat. No. 103046, 103065 - 103069). Cross-reactivity to ferret has been reported by a collaborator, but not verified in house.
更多信息或购买 :
公司信息
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品,旨在加速生命科学领域的研发工作。