产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
异硫氰酸荧光素抗小鼠/人类CD45R/B220
目录 :
103206
规格 :
500微克
价格 :
95美元
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
异硫氰酸荧光素
克隆名称 :
RA3-6B2
反应物种 :
人类, 小鼠
应用 :
流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 77
出版应用/物种/样本/稀释参考文献
  • 免疫组化-冰冻切片; 小鼠; 图 1h
Hammerich L, Marron T, Upadhyay R, Svensson Arvelund J, Dhainaut M, Hussein S, et al. Systemic clinical tumor regressions and potentiation of PD1 blockade with in situ vaccination. Nat Med. 2019;25:814-824 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s2b
Meyer I, Goetzke C, Kespohl M, Sauter M, Heuser A, Eckstein V, et al. Silencing the CSF-1 Axis Using Nanoparticle Encapsulated siRNA Mitigates Viral and Autoimmune Myocarditis. Front Immunol. 2018;9:2303 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:200; 图 s1a
Tang H, Liang Y, Anders R, Taube J, Qiu X, Mulgaonkar A, et al. PD-L1 on host cells is essential for PD-L1 blockade-mediated tumor regression. J Clin Invest. 2018;128:580-588 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1b
Mildner A, Schönheit J, Giladi A, David E, Lara Astiaso D, Lorenzo Vivas E, et al. Genomic Characterization of Murine Monocytes Reveals C/EBP? Transcription Factor Dependence of Ly6C- Cells. Immunity. 2017;46:849-862.e7 pubmed 出版商
  • 流式细胞仪; 人类; 1:100
Lu X, Chen Q, Rong Y, Yang G, Li C, Xu N, et al. LECT2 drives haematopoietic stem cell expansion and mobilization via regulating the macrophages and osteolineage cells. Nat Commun. 2016;7:12719 pubmed 出版商
  • 流式细胞仪; 小鼠
Leon Rico D, Fernández García M, Aldea M, Sánchez R, Peces Barba M, Martínez Palacio J, et al. Comparison of haematopoietic stem cell engraftment through the retro-orbital venous sinus and the lateral vein: alternative routes for bone marrow transplantation in mice. Lab Anim. 2015;49:132-41 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 6
  • 流式细胞仪; 小鼠; 图 4
Cao A, Yao S, Gong B, Nurieva R, Elson C, Cong Y. Interleukin (IL)-21 promotes intestinal IgA response to microbiota. Mucosal Immunol. 2015;8:1072-82 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3
Chaimowitz N, Falanga Y, Ryan J, Conrad D. Fyn kinase is required for optimal humoral responses. PLoS ONE. 2013;8:e60640 pubmed 出版商
Sanchez H, Moroney J, Gan H, Shen T, Im J, Li T, et al. B cell-intrinsic epigenetic modulation of antibody responses by dietary fiber-derived short-chain fatty acids. Nat Commun. 2020;11:60 pubmed 出版商
Garo L, Ajay A, Fujiwara M, Beynon V, Kuhn C, Gabriely G, et al. Smad7 Controls Immunoregulatory PDL2/1-PD1 Signaling in Intestinal Inflammation and Autoimmunity. Cell Rep. 2019;28:3353-3366.e5 pubmed 出版商
Tian D, Yang L, Wang S, Zhu Y, Shi W, Zhang C, et al. Double negative T cells mediate Lag3-dependent antigen-specific protection in allergic asthma. Nat Commun. 2019;10:4246 pubmed 出版商
Zhang H, Alsaleh G, Feltham J, Sun Y, Napolitano G, Riffelmacher T, et al. Polyamines Control eIF5A Hypusination, TFEB Translation, and Autophagy to Reverse B Cell Senescence. Mol Cell. 2019;76:110-125.e9 pubmed 出版商
Mariani S, Li Z, Rice S, Krieg C, Fragkogianni S, Robinson M, et al. Pro-inflammatory Aorta-Associated Macrophages Are Involved in Embryonic Development of Hematopoietic Stem Cells. Immunity. 2019;: pubmed 出版商
Nowlan B, Williams E, Doran M, Levesque J. CD27, CD201, FLT3, CD48, and CD150 cell surface staining identifies long-term mouse hematopoietic stem cells in immunodeficient non-obese diabetic severe combined immune deficient derived strains. Haematologica. 2019;: pubmed 出版商
Srivastava S, Salter A, Liggitt D, Yechan Gunja S, Sarvothama M, Cooper K, et al. Logic-Gated ROR1 Chimeric Antigen Receptor Expression Rescues T Cell-Mediated Toxicity to Normal Tissues and Enables Selective Tumor Targeting. Cancer Cell. 2019;35:489-503.e8 pubmed 出版商
Wang G, Zhang L, Zhao X, Gao S, Qu L, Yu H, et al. The Aryl hydrocarbon receptor mediates tobacco-induced PD-L1 expression and is associated with response to immunotherapy. Nat Commun. 2019;10:1125 pubmed 出版商
Roy K, Mitchell S, Liu Y, Ohta S, Lin Y, Metzig M, et al. A Regulatory Circuit Controlling the Dynamics of NFκB cRel Transitions B Cells from Proliferation to Plasma Cell Differentiation. Immunity. 2019;50:616-628.e6 pubmed 出版商
Dey A, Yang W, Gegonne A, Nishiyama A, Pan R, Yagi R, et al. BRD4 directs hematopoietic stem cell development and modulates macrophage inflammatory responses. EMBO J. 2019;38: pubmed 出版商
Wang B, Lim J, Kajikawa T, Li X, Vallance B, Moutsopoulos N, et al. Macrophage β2-Integrins Regulate IL-22 by ILC3s and Protect from Lethal Citrobacter rodentium-Induced Colitis. Cell Rep. 2019;26:1614-1626.e5 pubmed 出版商
Zanotti K, Maul R, Yang W, Gearhart P. DNA Breaks in Ig V Regions Are Predominantly Single Stranded and Are Generated by UNG and MSH6 DNA Repair Pathways. J Immunol. 2019;202:1573-1581 pubmed 出版商
Zegarra Ruiz D, El Beidaq A, Iñiguez A, Lubrano Di Ricco M, Manfredo Vieira S, Ruff W, et al. A Diet-Sensitive Commensal Lactobacillus Strain Mediates TLR7-Dependent Systemic Autoimmunity. Cell Host Microbe. 2019;25:113-127.e6 pubmed 出版商
Greenwald A, Licht T, Kumar S, Oladipupo S, Iyer S, Grunewald M, et al. VEGF expands erythropoiesis via hypoxia-independent induction of erythropoietin in noncanonical perivascular stromal cells. J Exp Med. 2019;216:215-230 pubmed 出版商
Kim C, Lee C, Jung J, Ghosh A, Hasan S, Hwang S, et al. The Transcription Factor Ets1 Suppresses T Follicular Helper Type 2 Cell Differentiation to Halt the Onset of Systemic Lupus Erythematosus. Immunity. 2018;49:1034-1048.e8 pubmed 出版商
Katsumura K, Mehta C, Hewitt K, Soukup A, Fraga de Andrade I, Ranheim E, et al. Human leukemia mutations corrupt but do not abrogate GATA-2 function. Proc Natl Acad Sci U S A. 2018;115:E10109-E10118 pubmed 出版商
Delgado Benito V, Rosen D, Wang Q, Gazumyan A, Pai J, Oliveira T, et al. The Chromatin Reader ZMYND8 Regulates Igh Enhancers to Promote Immunoglobulin Class Switch Recombination. Mol Cell. 2018;72:636-649.e8 pubmed 出版商
Stewart I, Radtke D, Phillips B, McGowan S, Bannard O. Germinal Center B Cells Replace Their Antigen Receptors in Dark Zones and Fail Light Zone Entry when Immunoglobulin Gene Mutations are Damaging. Immunity. 2018;49:477-489.e7 pubmed 出版商
Golan K, Kumari A, Kollet O, Khatib Massalha E, Subramaniam M, Ferreira Z, et al. Daily Onset of Light and Darkness Differentially Controls Hematopoietic Stem Cell Differentiation and Maintenance. Cell Stem Cell. 2018;23:572-585.e7 pubmed 出版商
Ghezraoui H, Oliveira C, Becker J, Bilham K, Moralli D, Anzilotti C, et al. 53BP1 cooperation with the REV7-shieldin complex underpins DNA structure-specific NHEJ. Nature. 2018;560:122-127 pubmed 出版商
Xiang W, Shi R, Kang X, Zhang X, Chen P, Zhang L, et al. Monoacylglycerol lipase regulates cannabinoid receptor 2-dependent macrophage activation and cancer progression. Nat Commun. 2018;9:2574 pubmed 出版商
Weng T, Wu H, Li C, Hung Y, Chang Y, Chen Y, et al. Homoharringtonine induced immune alteration for an Efficient Anti-tumor Response in Mouse Models of Non-small Cell Lung Adenocarcinoma Expressing Kras Mutation. Sci Rep. 2018;8:8216 pubmed 出版商
Liu R, King A, Bouillet P, Tarlinton D, Strasser A, Heierhorst J. Proapoptotic BIM Impacts B Lymphoid Homeostasis by Limiting the Survival of Mature B Cells in a Cell-Autonomous Manner. Front Immunol. 2018;9:592 pubmed 出版商
Nakamura K, Kassem S, Cleynen A, Chrétien M, Guillerey C, Putz E, et al. Dysregulated IL-18 Is a Key Driver of Immunosuppression and a Possible Therapeutic Target in the Multiple Myeloma Microenvironment. Cancer Cell. 2018;33:634-648.e5 pubmed 出版商
Laban H, Weigert A, Zink J, Elgheznawy A, Schürmann C, Günther L, et al. VASP regulates leukocyte infiltration, polarization, and vascular repair after ischemia. J Cell Biol. 2018;217:1503-1519 pubmed 出版商
Mrdjen D, Pavlovic A, Hartmann F, Schreiner B, Utz S, Leung B, et al. High-Dimensional Single-Cell Mapping of Central Nervous System Immune Cells Reveals Distinct Myeloid Subsets in Health, Aging, and Disease. Immunity. 2018;48:380-395.e6 pubmed 出版商
Emgård J, Kammoun H, García Cassani B, Chesne J, Parigi S, Jacob J, et al. Oxysterol Sensing through the Receptor GPR183 Promotes the Lymphoid-Tissue-Inducing Function of Innate Lymphoid Cells and Colonic Inflammation. Immunity. 2018;48:120-132.e8 pubmed 出版商
Reismann D, Stefanowski J, Gunther R, Rakhymzhan A, Matthys R, Nützi R, et al. Longitudinal intravital imaging of the femoral bone marrow reveals plasticity within marrow vasculature. Nat Commun. 2017;8:2153 pubmed 出版商
Burton O, Tamayo J, Stranks A, Miller S, Koleoglou K, Weinberg E, et al. IgE promotes type 2 innate lymphoid cells in murine food allergy. Clin Exp Allergy. 2017;: pubmed 出版商
Schüler F, Weiss J, Lindner S, Lohmüller M, Herzog S, Spiegl S, et al. Checkpoint kinase 1 is essential for normal B cell development and lymphomagenesis. Nat Commun. 2017;8:1697 pubmed 出版商
Clemente Casares X, Hosseinzadeh S, Barbu I, Dick S, Macklin J, Wang Y, et al. A CD103+ Conventional Dendritic Cell Surveillance System Prevents Development of Overt Heart Failure during Subclinical Viral Myocarditis. Immunity. 2017;47:974-989.e8 pubmed 出版商
Huang L, Zhang Y, Xu C, Gu X, Niu L, Wang J, et al. Rictor positively regulates B cell receptor signaling by modulating actin reorganization via ezrin. PLoS Biol. 2017;15:e2001750 pubmed 出版商
Galani I, Triantafyllia V, Eleminiadou E, Koltsida O, Stavropoulos A, Manioudaki M, et al. Interferon-? Mediates Non-redundant Front-Line Antiviral Protection against Influenza Virus Infection without Compromising Host Fitness. Immunity. 2017;46:875-890.e6 pubmed 出版商
Zhu X, Yuan Z, Yan P, Li Y, Jiang H, Huang S. Effect of iRoot SP and mineral trioxide aggregate (MTA) on the viability and polarization of macrophages. Arch Oral Biol. 2017;80:27-33 pubmed 出版商
Velazquez V, Meadows A, Pineda R, Camboni M, McCarty D, Fu H. Effective Depletion of Pre-existing Anti-AAV Antibodies Requires Broad Immune Targeting. Mol Ther Methods Clin Dev. 2017;4:159-168 pubmed 出版商
Takahashi T, Asano Y, Sugawara K, Yamashita T, Nakamura K, Saigusa R, et al. Epithelial Fli1 deficiency drives systemic autoimmunity and fibrosis: Possible roles in scleroderma. J Exp Med. 2017;214:1129-1151 pubmed 出版商
Furuta Y, Tsai S, Kinoshita M, Fujimoto K, Okumura R, Umemoto E, et al. E-NPP3 controls plasmacytoid dendritic cell numbers in the small intestine. PLoS ONE. 2017;12:e0172509 pubmed 出版商
St Clair J, Detanico T, Aviszus K, Kirchenbaum G, Christie M, Carpenter J, et al. Immunogenicity of Isogenic IgG in Aggregates and Immune Complexes. PLoS ONE. 2017;12:e0170556 pubmed 出版商
Hrdinka M, Sudan K, Just S, Drobek A, Stepanek O, Schluter D, et al. Normal Development and Function of T Cells in Proline Rich 7 (Prr7) Deficient Mice. PLoS ONE. 2016;11:e0162863 pubmed 出版商
Rossnagl S, Altrock E, Sens C, Kraft S, Rau K, Milsom M, et al. EDA-Fibronectin Originating from Osteoblasts Inhibits the Immune Response against Cancer. PLoS Biol. 2016;14:e1002562 pubmed 出版商
Tan X, Fujiu K, Manabe I, Nishida J, Yamagishi R, Terashima Y, et al. Choroidal Neovascularization Is Inhibited in Splenic-Denervated or Splenectomized Mice with a Concomitant Decrease in Intraocular Macrophage. PLoS ONE. 2016;11:e0160985 pubmed 出版商
Jones M, DeWolf S, Vacharathit V, Yim M, Spencer S, Bamezai A. Investigating B Cell Development, Natural and Primary Antibody Responses in Ly-6A/Sca-1 Deficient Mice. PLoS ONE. 2016;11:e0157271 pubmed 出版商
Georgoudaki A, Prokopec K, Boura V, Hellqvist E, Sohn S, Östling J, et al. Reprogramming Tumor-Associated Macrophages by Antibody Targeting Inhibits Cancer Progression and Metastasis. Cell Rep. 2016;15:2000-11 pubmed 出版商
Wang X, Ma K, Chen M, Ko K, Zheng B, Lu L. IL-17A Promotes Pulmonary B-1a Cell Differentiation via Induction of Blimp-1 Expression during Influenza Virus Infection. PLoS Pathog. 2016;12:e1005367 pubmed 出版商
Hata E, Sasaki N, Takeda A, Tohya K, Umemoto E, Akahoshi N, et al. Lysophosphatidic acid receptors LPA4 and LPA6 differentially promote lymphocyte transmigration across high endothelial venules in lymph nodes. Int Immunol. 2016;28:283-92 pubmed 出版商
Kondo M, Tanaka Y, Kuwabara T, Naito T, Kohwi Shigematsu T, Watanabe A. SATB1 Plays a Critical Role in Establishment of Immune Tolerance. J Immunol. 2016;196:563-72 pubmed 出版商
Uematsu T, Iizasa E, Kobayashi N, Yoshida H, Hara H. Loss of CARD9-mediated innate activation attenuates severe influenza pneumonia without compromising host viral immunity. Sci Rep. 2015;5:17577 pubmed 出版商
Engel O, Akyüz L, da Costa Goncalves A, Winek K, Dames C, Thielke M, et al. Cholinergic Pathway Suppresses Pulmonary Innate Immunity Facilitating Pneumonia After Stroke. Stroke. 2015;46:3232-40 pubmed 出版商
Ku C, Lim K, Kalantry S, Maillard I, Engel J, Hosoya T. A monoallelic-to-biallelic T-cell transcriptional switch regulates GATA3 abundance. Genes Dev. 2015;29:1930-41 pubmed 出版商
Pang D, Irvine K, Mehdi A, Thomas H, Harris M, Hamilton Williams E, et al. Expression profiling pre-diabetic mice to uncover drugs with clinical application to type 1 diabetes. Clin Transl Immunology. 2015;4:e41 pubmed 出版商
Ma Y, Huang F, Cong L, Gong W, Bai H, Li J, et al. IL-4-Producing Dendritic Cells Induced during Schistosoma japonica Infection Promote Th2 Cells via IL-4-Dependent Pathway. J Immunol. 2015;195:3769-80 pubmed 出版商
Wu Y, Wu Y, Mo S, Hsiao H, He Y, Lai M. Cellular FLIP Inhibits Myeloid Cell Activation by Suppressing Selective Innate Signaling. J Immunol. 2015;195:2612-23 pubmed 出版商
Kim B, Sasaki Y, Egawa T. Restriction of Nonpermissive RUNX3 Protein Expression in T Lymphocytes by the Kozak Sequence. J Immunol. 2015;195:1517-23 pubmed 出版商
Morrison V, Uotila L, Llort Asens M, Savinko T, Fagerholm S. Optimal T Cell Activation and B Cell Antibody Responses In Vivo Require the Interaction between Leukocyte Function-Associated Antigen-1 and Kindlin-3. J Immunol. 2015;195:105-15 pubmed 出版商
Hayashi K, Sasai M, Iwasaki A. Toll-like receptor 9 trafficking and signaling for type I interferons requires PIKfyve activity. Int Immunol. 2015;27:435-45 pubmed 出版商
Lunardi A, Varmeh S, Chen M, Taulli R, Guarnerio J, Ala U, et al. Suppression of CHK1 by ETS Family Members Promotes DNA Damage Response Bypass and Tumorigenesis. Cancer Discov. 2015;5:550-63 pubmed 出版商
Kaku H, Cheng K, Al Abed Y, Rothstein T. A novel mechanism of B cell-mediated immune suppression through CD73 expression and adenosine production. J Immunol. 2014;193:5904-13 pubmed 出版商
Al Barwani F, Young S, Baird M, Larsen D, Ward V. Mannosylation of virus-like particles enhances internalization by antigen presenting cells. PLoS ONE. 2014;9:e104523 pubmed 出版商
Hsieh Y, Fu C, Hsieh M. Helminth-induced interleukin-4 abrogates invariant natural killer T cell activation-associated clearance of bacterial infection. Infect Immun. 2014;82:2087-97 pubmed 出版商
Xia S, Wei J, Wang J, Sun H, Zheng W, Li Y, et al. A requirement of dendritic cell-derived interleukin-27 for the tumor infiltration of regulatory T cells. J Leukoc Biol. 2014;95:733-742 pubmed
Murakami R, Denda Nagai K, Hashimoto S, Nagai S, Hattori M, Irimura T. A unique dermal dendritic cell subset that skews the immune response toward Th2. PLoS ONE. 2013;8:e73270 pubmed 出版商
Ota T, Doyle Cooper C, Cooper A, Doores K, Aoki Ota M, Le K, et al. B cells from knock-in mice expressing broadly neutralizing HIV antibody b12 carry an innocuous B cell receptor responsive to HIV vaccine candidates. J Immunol. 2013;191:3179-85 pubmed 出版商
Fujikura D, Chiba S, Muramatsu D, Kazumata M, Nakayama Y, Kawai T, et al. Type-I interferon is critical for FasL expression on lung cells to determine the severity of influenza. PLoS ONE. 2013;8:e55321 pubmed 出版商
Carbonneau C, Despars G, Rojas Sutterlin S, Fortin A, Le O, Hoang T, et al. Ionizing radiation-induced expression of INK4a/ARF in murine bone marrow-derived stromal cell populations interferes with bone marrow homeostasis. Blood. 2012;119:717-26 pubmed 出版商
Kelly L, Pereira J, Yi T, Xu Y, Cyster J. EBI2 guides serial movements of activated B cells and ligand activity is detectable in lymphoid and nonlymphoid tissues. J Immunol. 2011;187:3026-32 pubmed 出版商
Ota T, Ota M, Duong B, Gavin A, Nemazee D. Liver-expressed Igkappa superantigen induces tolerance of polyclonal B cells by clonal deletion not kappa to lambda receptor editing. J Exp Med. 2011;208:617-29 pubmed 出版商
del Rio M, Cote Sierra J, Rodriguez Barbosa J. Flt3L-mobilized dendritic cells bearing H2-Kbm1 apoptotic cells do not induce cross-tolerance to CD8+ T cells across a class I MHC mismatched barrier. Transpl Int. 2011;24:501-13 pubmed 出版商
Charles N, Hardwick D, Daugas E, Illei G, Rivera J. Basophils and the T helper 2 environment can promote the development of lupus nephritis. Nat Med. 2010;16:701-7 pubmed 出版商
Lang G, Devera T, Lang M. Requirement for CD1d expression by B cells to stimulate NKT cell-enhanced antibody production. Blood. 2008;111:2158-62 pubmed
产品信息
抗原 :
CD45R
Apps. Abbrev. :
流式细胞仪
目录 :
103206
克隆 :
RA3-6B2
产品 :
异硫氰酸荧光素抗小鼠/人类CD45R/B220
抗体亚型 :
Rat IgG2a, κ
其他名称 :
B220
规格 :
500微克
价格(美元) :
95美元
反应物种 :
Mouse, Human, Cross-Reactivity: Cat (Feline)
克隆性 :
单克隆
宿主 :
大鼠
共轭标签/标签/标记 :
异硫氰酸荧光素
免疫原 :
Abelson murine leukemia virus-induced pre-B tumor cells
应用注释 :
Clone RA3-6B2 has been described to react with an epitope on the extracellular domain of the transmembrane CD45 glycoprotein which is dependent upon the expression of exon A and specific carbohydrate residues. Additional reported applications (for the relevant formats) include: immunoprecipitation 1 , in vitro and in vivo modulation of B cell responses 2-4 , and immunohistochemistry of acetone-fixed frozen sections and formalin-fixed paraffin-embedded sections 5,6 .
更多信息或购买 :
公司信息
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品,旨在加速生命科学领域的研发工作。