产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
APC抗小鼠CD117(C-kit)
目录 :
105812
规格 :
100微克
价格 :
209美元
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
APC
克隆名称 :
2B8
反应物种 :
小鼠
应用 :
免疫组化, 流式细胞仪
更多信息或购买 :
文章摘录数: 77
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 0.25 ug/ml; 图 3a
Mehatre S, Roy I, Biswas A, Prit D, Schouteden S, Huelsken J, et al. Niche-Mediated Integrin Signaling Supports Steady-State Hematopoiesis in the Spleen. J Immunol. 2021;206:1549-1560 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s9b
Chen J, Sivan U, Tan S, Lippo L, De Angelis J, Labella R, et al. High-resolution 3D imaging uncovers organ-specific vascular control of tissue aging. Sci Adv. 2021;7: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s1b
Wilson Z, Witt H, Hazlett L, Harman M, Neumann B, Whitman A, et al. Context-Dependent Role of Vinculin in Neutrophil Adhesion, Motility and Trafficking. Sci Rep. 2020;10:2142 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:200; 图 e3m
Yoshimi A, Lin K, Wiseman D, Rahman M, Pastore A, Wang B, et al. Coordinated alterations in RNA splicing and epigenetic regulation drive leukaemogenesis. Nature. 2019;574:273-277 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1f
Dey A, Yang W, Gegonne A, Nishiyama A, Pan R, Yagi R, et al. BRD4 directs hematopoietic stem cell development and modulates macrophage inflammatory responses. EMBO J. 2019;38: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1a, s9
Halvarsson C, Rörby E, Eliasson P, Lang S, Soneji S, Jönsson J. Putative role of NF-kB but not HIF-1α in hypoxia-dependent regulation of oxidative stress in hematopoietic stem and progenitor cells. Antioxid Redox Signal. 2019;: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1d
Cai Z, Kotzin J, Ramdas B, Chen S, Nelanuthala S, Palam L, et al. Inhibition of Inflammatory Signaling in Tet2 Mutant Preleukemic Cells Mitigates Stress-Induced Abnormalities and Clonal Hematopoiesis. Cell Stem Cell. 2018;23:833-849.e5 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s2b
Gozdecka M, Meduri E, Mazan M, Tzelepis K, Dudek M, Knights A, et al. UTX-mediated enhancer and chromatin remodeling suppresses myeloid leukemogenesis through noncatalytic inverse regulation of ETS and GATA programs. Nat Genet. 2018;50:883-894 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s2a
Rychtarčíková Z, Lettlova S, Tomkova V, Korenkova V, Langerova L, Simonova E, et al. Tumor-initiating cells of breast and prostate origin show alterations in the expression of genes related to iron metabolism. Oncotarget. 2017;8:6376-6398 pubmed 出版商
  • 流式细胞仪; 小鼠; 0.2-0.8 ug/ml; 图 s20
Bahal R, Ali McNeer N, Quijano E, Liu Y, Sulkowski P, Turchick A, et al. In vivo correction of anaemia in ?-thalassemic mice by ?PNA-mediated gene editing with nanoparticle delivery. Nat Commun. 2016;7:13304 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:50
Lu X, Chen Q, Rong Y, Yang G, Li C, Xu N, et al. LECT2 drives haematopoietic stem cell expansion and mobilization via regulating the macrophages and osteolineage cells. Nat Commun. 2016;7:12719 pubmed 出版商
  • 流式细胞仪; 小鼠
Holzapfel B, Hutmacher D, Nowlan B, Barbier V, Thibaudeau L, Theodoropoulos C, et al. Tissue engineered humanized bone supports human hematopoiesis in vivo. Biomaterials. 2015;61:103-14 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2
Di C, Lin X, Zhang Y, Zhong W, Yuan Y, Zhou T, et al. Basophil-associated OX40 ligand participates in the initiation of Th2 responses during airway inflammation. J Biol Chem. 2015;290:12523-36 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3a
  • 免疫组化; 小鼠; 图 s5
Koh F, Lizama C, Wong P, Hawkins J, Zovein A, Ramalho Santos M. Emergence of hematopoietic stem and progenitor cells involves a Chd1-dependent increase in total nascent transcription. Proc Natl Acad Sci U S A. 2015;112:E1734-43 pubmed 出版商
  • 流式细胞仪; 小鼠
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Koide S, Sigurdsson V, Radulović V, Saito K, Zheng Z, Lang S, et al. CD244 expression represents functional decline of murine hematopoietic stem cells after in vitro culture. iScience. 2022;25:103603 pubmed 出版商
Lawson H, van de Lagemaat L, Barile M, Tavosanis A, Durko J, Villacreces A, et al. CITED2 coordinates key hematopoietic regulatory pathways to maintain the HSC pool in both steady-state hematopoiesis and transplantation. Stem Cell Reports. 2021;16:2784-2797 pubmed 出版商
Beauchamp E, Leventhal M, Bernard E, Hoppe E, Todisco G, Creignou M, et al. ZBTB33 is mutated in clonal hematopoiesis and myelodysplastic syndromes and impacts RNA splicing. Blood Cancer Discov. 2021;2:500-517 pubmed 出版商
Yu K, Hammerschmidt S, Permanyer M, Galla M, Rothe M, Zheng X, et al. Targeted delivery of regulatory macrophages to lymph nodes interferes with T cell priming by preventing the formation of stable immune synapses. Cell Rep. 2021;35:109273 pubmed 出版商
Inverso D, Shi J, Lee K, Jakab M, Ben Moshe S, Kulkarni S, et al. A spatial vascular transcriptomic, proteomic, and phosphoproteomic atlas unveils an angiocrine Tie-Wnt signaling axis in the liver. Dev Cell. 2021;56:1677-1693.e10 pubmed 出版商
Barkaway A, Rolas L, Joulia R, Bodkin J, Lenn T, Owen Woods C, et al. Age-related changes in the local milieu of inflamed tissues cause aberrant neutrophil trafficking and subsequent remote organ damage. Immunity. 2021;54:1494-1510.e7 pubmed 出版商
Paiva R, Sousa A, Ramos C, Avila M, Lilue J, Paixão T, et al. Self-renewal of double-negative 3 early thymocytes enables thymus autonomy but compromises the β-selection checkpoint. Cell Rep. 2021;35:108967 pubmed 出版商
Jassinskaja M, Pimková K, Arh N, Johansson E, Davoudi M, Pereira C, et al. Ontogenic shifts in cellular fate are linked to proteotype changes in lineage-biased hematopoietic progenitor cells. Cell Rep. 2021;34:108894 pubmed 出版商
Suzuki S, McCarrey J, Hermann B. An mTORC1-dependent switch orchestrates the transition between mouse spermatogonial stem cells and clones of progenitor spermatogonia. Cell Rep. 2021;34:108752 pubmed 出版商
Nguyen D, Soygur B, Peng S, Malki S, Hu G, Laird D. Apoptosis in the fetal testis eliminates developmentally defective germ cell clones. Nat Cell Biol. 2020;22:1423-1435 pubmed 出版商
Ritter M, Klimiankou M, Klimenkova O, Schambach A, Hoffmann D, Schmidt A, et al. Cooperating, congenital neutropenia-associated Csf3r and Runx1 mutations activate pro-inflammatory signaling and inhibit myeloid differentiation of mouse HSPCs. Ann Hematol. 2020;99:2329-2338 pubmed 出版商
Wang X, Yang L, Wang Y, Xu Z, Feng Y, Zhang J, et al. Comparative analysis of cell lineage differentiation during hepatogenesis in humans and mice at the single-cell transcriptome level. Cell Res. 2020;30:1109-1126 pubmed 出版商
Tran N, Trombke J, Rajewsky K, Chu V. Protocol for Efficient CRISPR/Cas9/AAV-Mediated Homologous Recombination in Mouse Hematopoietic Stem and Progenitor Cells. STAR Protoc. 2020;1:100028 pubmed 出版商
Pessoa Rodrigues C, Herman J, Herquel B, Valsecchi C, Stehle T, Grün D, et al. Temporal expression of MOF acetyltransferase primes transcription factor networks for erythroid fate. Sci Adv. 2020;6:eaaz4815 pubmed 出版商
Cai Z, Aguilera F, Ramdas B, Daulatabad S, Srivastava R, Kotzin J, et al. Targeting Bim via a lncRNA Morrbid Regulates the Survival of Preleukemic and Leukemic Cells. Cell Rep. 2020;31:107816 pubmed 出版商
Gao Y, Vasic R, Song Y, Teng R, Liu C, Gbyli R, et al. m6A Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development. Immunity. 2020;52:1007-1021.e8 pubmed 出版商
He M, Chiang H, Luo H, Zheng Z, Qiao Q, Wang L, et al. An Acetylation Switch of the NLRP3 Inflammasome Regulates Aging-Associated Chronic Inflammation and Insulin Resistance. Cell Metab. 2020;31:580-591.e5 pubmed 出版商
Li K, Liu Y, Cao H, Zhang Y, Gu Z, Liu X, et al. Interrogation of enhancer function by enhancer-targeting CRISPR epigenetic editing. Nat Commun. 2020;11:485 pubmed 出版商
Chen C, Li B, Millman S, Chen C, Li X, Morris J, et al. Vitamin B6 Addiction in Acute Myeloid Leukemia. Cancer Cell. 2020;37:71-84.e7 pubmed 出版商
Davis F, Schaller M, denDekker A, Joshi A, Kimball A, Evanoff H, et al. Sepsis Induces Prolonged Epigenetic Modifications in Bone Marrow and Peripheral Macrophages Impairing Inflammation and Wound Healing. Arterioscler Thromb Vasc Biol. 2019;39:2353-2366 pubmed 出版商
Tran N, Sommermann T, Graf R, Trombke J, Pempe J, Petsch K, et al. Efficient CRISPR/Cas9-Mediated Gene Knockin in Mouse Hematopoietic Stem and Progenitor Cells. Cell Rep. 2019;28:3510-3522.e5 pubmed 出版商
Viny A, Bowman R, Liu Y, Lavallée V, Eisman S, Xiao W, et al. Cohesin Members Stag1 and Stag2 Display Distinct Roles in Chromatin Accessibility and Topological Control of HSC Self-Renewal and Differentiation. Cell Stem Cell. 2019;25:682-696.e8 pubmed 出版商
Brian B, Jolicoeur A, Guerrero C, Nunez M, Sychev Z, Hegre S, et al. Unique-region phosphorylation targets LynA for rapid degradation, tuning its expression and signaling in myeloid cells. elife. 2019;8: pubmed 出版商
Radulović V, van der Garde M, Koide S, Sigurdsson V, Lang S, Kaneko S, et al. Junctional Adhesion Molecule 2 Represents a Subset of Hematopoietic Stem Cells with Enhanced Potential for T Lymphopoiesis. Cell Rep. 2019;27:2826-2836.e5 pubmed 出版商
Legrand J, Chan A, La H, Rossello F, Ankö M, Fuller Pace F, et al. DDX5 plays essential transcriptional and post-transcriptional roles in the maintenance and function of spermatogonia. Nat Commun. 2019;10:2278 pubmed 出版商
Tsuchiya K, Nakajima S, Hosojima S, Thi Nguyen D, Hattori T, Manh Le T, et al. Caspase-1 initiates apoptosis in the absence of gasdermin D. Nat Commun. 2019;10:2091 pubmed 出版商
Paris J, Morgan M, Campos J, Spencer G, Shmakova A, Ivanova I, et al. Targeting the RNA m6A Reader YTHDF2 Selectively Compromises Cancer Stem Cells in Acute Myeloid Leukemia. Cell Stem Cell. 2019;: pubmed 出版商
Hu Q, Sun W, Wang J, Ruan H, Zhang X, Ye Y, et al. Conjugation of haematopoietic stem cells and platelets decorated with anti-PD-1 antibodies augments anti-leukaemia efficacy. Nat Biomed Eng. 2018;2:831-840 pubmed 出版商
Kubota S, Tokunaga K, Umezu T, Yokomizo Nakano T, Sun Y, Oshima M, et al. Lineage-specific RUNX2 super-enhancer activates MYC and promotes the development of blastic plasmacytoid dendritic cell neoplasm. Nat Commun. 2019;10:1653 pubmed 出版商
Sibon D, Coman T, Rossignol J, Lamarque M, Kosmider O, Bayard E, et al. Enhanced Renewal of Erythroid Progenitors in Myelodysplastic Anemia by Peripheral Serotonin. Cell Rep. 2019;26:3246-3256.e4 pubmed 出版商
Srivastava S, Salter A, Liggitt D, Yechan Gunja S, Sarvothama M, Cooper K, et al. Logic-Gated ROR1 Chimeric Antigen Receptor Expression Rescues T Cell-Mediated Toxicity to Normal Tissues and Enables Selective Tumor Targeting. Cancer Cell. 2019;35:489-503.e8 pubmed 出版商
Luo H, Mu W, Karki R, Chiang H, Mohrin M, Shin J, et al. Mitochondrial Stress-Initiated Aberrant Activation of the NLRP3 Inflammasome Regulates the Functional Deterioration of Hematopoietic Stem Cell Aging. Cell Rep. 2019;26:945-954.e4 pubmed 出版商
Säwén P, Eldeeb M, Erlandsson E, Kristiansen T, Laterza C, Kokaia Z, et al. Murine HSCs contribute actively to native hematopoiesis but with reduced differentiation capacity upon aging. elife. 2018;7: pubmed 出版商
Mann M, Mehta A, de Boer C, Kowalczyk M, Lee K, Haldeman P, et al. Heterogeneous Responses of Hematopoietic Stem Cells to Inflammatory Stimuli Are Altered with Age. Cell Rep. 2018;25:2992-3005.e5 pubmed 出版商
Chen Z, Amro E, Becker F, Holzer M, Rasa S, Njeru S, et al. Cohesin-mediated NF-κB signaling limits hematopoietic stem cell self-renewal in aging and inflammation. J Exp Med. 2019;216:152-175 pubmed 出版商
Zhu H, Zhang L, Wu Y, Dong B, Guo W, Wang M, et al. T-ALL leukemia stem cell 'stemness' is epigenetically controlled by the master regulator SPI1. elife. 2018;7: pubmed 出版商
Sun Y, Zhou B, Mao F, Xu J, Miao H, Zou Z, et al. HOXA9 Reprograms the Enhancer Landscape to Promote Leukemogenesis. Cancer Cell. 2018;34:643-658.e5 pubmed 出版商
Parada Kusz M, Penaranda C, Hagedorn E, Clatworthy A, Nair A, Henninger J, et al. Generation of mouse-zebrafish hematopoietic tissue chimeric embryos for hematopoiesis and host-pathogen interaction studies. Dis Model Mech. 2018;11: pubmed 出版商
Plein A, Fantin A, Denti L, Pollard J, Ruhrberg C. Erythro-myeloid progenitors contribute endothelial cells to blood vessels. Nature. 2018;562:223-228 pubmed 出版商
Golan K, Kumari A, Kollet O, Khatib Massalha E, Subramaniam M, Ferreira Z, et al. Daily Onset of Light and Darkness Differentially Controls Hematopoietic Stem Cell Differentiation and Maintenance. Cell Stem Cell. 2018;23:572-585.e7 pubmed 出版商
Gao B, Lin X, Jing H, Fan J, Ji C, Jie Q, et al. Local delivery of tetramethylpyrazine eliminates the senescent phenotype of bone marrow mesenchymal stromal cells and creates an anti-inflammatory and angiogenic environment in aging mice. Aging Cell. 2018;17:e12741 pubmed 出版商
Guo B, Huang X, Lee M, Lee S, Broxmeyer H. Antagonism of PPAR-γ signaling expands human hematopoietic stem and progenitor cells by enhancing glycolysis. Nat Med. 2018;24:360-367 pubmed 出版商
Kunimoto H, Meydan C, Nazir A, Whitfield J, Shank K, Rapaport F, et al. Cooperative Epigenetic Remodeling by TET2 Loss and NRAS Mutation Drives Myeloid Transformation and MEK Inhibitor Sensitivity. Cancer Cell. 2018;33:44-59.e8 pubmed 出版商
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Nihon Yanagi Y, Terai K, Murano T, Kawai T, Kimura S, Okazumi S. ?-2 microglobulin is unsuitable as an internal reference gene for the analysis of gene expression in human colorectal cancer. Biomed Rep. 2013;1:193-196 pubmed
Christoforou N, Liau B, Chakraborty S, Chellapan M, Bursac N, Leong K. Induced pluripotent stem cell-derived cardiac progenitors differentiate to cardiomyocytes and form biosynthetic tissues. PLoS ONE. 2013;8:e65963 pubmed 出版商
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产品信息
抗原 :
CD117
Apps. Abbrev. :
流式细胞仪
目录 :
105812
克隆 :
2B8
产品 :
APC抗小鼠CD117(C-kit)
抗体亚型 :
Rat IgG2b, κ
其他名称 :
c-KIT, 干细胞因子受体(SCFR)
规格 :
100微克
价格(美元) :
209美元
反应物种 :
小鼠
克隆性 :
单克隆
宿主 :
大鼠
共轭标签/标签/标记 :
APC
免疫原 :
小鼠骨髓肥大细胞
应用注释 :
Additional reported applications (for the relevant formats) include: immunoprecipitation 1 , immunohistochemistry of acetone fixed frozen sections 2 , and spatial biology (IBEX) 5,6 . The 2B8 antibody does not block c-Kit activity.
更多信息或购买 :
公司信息
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品,旨在加速生命科学领域的研发工作。