产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
PE/Cyanine7 anti-mouse Ly-6G/Ly-6C (Gr-1)
目录 :
108416
规格 :
100微克
价格 :
180美元
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
PE/Cy7
克隆名称 :
RB6-8C5
反应物种 :
小鼠
应用 :
流式细胞仪
更多信息或购买 :
文章摘录数: 41
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 1 ug/ml; 图 s12
Sweere J, Van Belleghem J, Ishak H, Bach M, Popescu M, Sunkari V, et al. Bacteriophage trigger antiviral immunity and prevent clearance of bacterial infection. Science. 2019;363: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4b
Ellman D, Degn M, Lund M, Clausen B, Novrup H, Flæng S, et al. Genetic Ablation of Soluble TNF Does Not Affect Lesion Size and Functional Recovery after Moderate Spinal Cord Injury in Mice. Mediators Inflamm. 2016;2016:2684098 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1c
Clausen B, Degn M, Sivasaravanaparan M, Fogtmann T, Andersen M, Trojanowsky M, et al. Conditional ablation of myeloid TNF increases lesion volume after experimental stroke in mice, possibly via altered ERK1/2 signaling. Sci Rep. 2016;6:29291 pubmed 出版商
  • 流式细胞仪; 小鼠
Mall C, Sckisel G, Proia D, Mirsoian A, Grossenbacher S, Pai C, et al. Repeated PD-1/PD-L1 monoclonal antibody administration induces fatal xenogeneic hypersensitivity reactions in a murine model of breast cancer. Oncoimmunology. 2016;5:e1075114 pubmed
  • 流式细胞仪; 小鼠; 图 s4
Yang Y, Xu J, Chen H, Fei X, Tang Y, Yan Y, et al. MiR-128-2 inhibits common lymphoid progenitors from developing into progenitor B cells. Oncotarget. 2016;7:17520-31 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:400; 图 1
Rathert P, Roth M, Neumann T, Muerdter F, Roe J, Muhar M, et al. Transcriptional plasticity promotes primary and acquired resistance to BET inhibition. Nature. 2015;525:543-547 pubmed 出版商
  • 流式细胞仪; 小鼠
Xu G, Wu H, Zhang J, Li D, Wang Y, Wang Y, et al. Metformin ameliorates ionizing irradiation-induced long-term hematopoietic stem cell injury in mice. Free Radic Biol Med. 2015;87:15-25 pubmed 出版商
  • 流式细胞仪; 小鼠
Kent D, Li J, Tanna H, Fink J, Kirschner K, Pask D, et al. Self-renewal of single mouse hematopoietic stem cells is reduced by JAK2V617F without compromising progenitor cell expansion. PLoS Biol. 2013;11:e1001576 pubmed 出版商
Li K, Liu Y, Cao H, Zhang Y, Gu Z, Liu X, et al. Interrogation of enhancer function by enhancer-targeting CRISPR epigenetic editing. Nat Commun. 2020;11:485 pubmed 出版商
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Tran N, Sommermann T, Graf R, Trombke J, Pempe J, Petsch K, et al. Efficient CRISPR/Cas9-Mediated Gene Knockin in Mouse Hematopoietic Stem and Progenitor Cells. Cell Rep. 2019;28:3510-3522.e5 pubmed 出版商
Paris J, Morgan M, Campos J, Spencer G, Shmakova A, Ivanova I, et al. Targeting the RNA m6A Reader YTHDF2 Selectively Compromises Cancer Stem Cells in Acute Myeloid Leukemia. Cell Stem Cell. 2019;: pubmed 出版商
Luo H, Mu W, Karki R, Chiang H, Mohrin M, Shin J, et al. Mitochondrial Stress-Initiated Aberrant Activation of the NLRP3 Inflammasome Regulates the Functional Deterioration of Hematopoietic Stem Cell Aging. Cell Rep. 2019;26:945-954.e4 pubmed 出版商
Celik H, Koh W, Kramer A, Ostrander E, Mallaney C, Fisher D, et al. JARID2 Functions as a Tumor Suppressor in Myeloid Neoplasms by Repressing Self-Renewal in Hematopoietic Progenitor Cells. Cancer Cell. 2018;34:741-756.e8 pubmed 出版商
Katsumura K, Mehta C, Hewitt K, Soukup A, Fraga de Andrade I, Ranheim E, et al. Human leukemia mutations corrupt but do not abrogate GATA-2 function. Proc Natl Acad Sci U S A. 2018;115:E10109-E10118 pubmed 出版商
Li A, Barsoumian H, Schoenhals J, Cushman T, Caetano M, Wang X, et al. Indoleamine 2,3-dioxygenase 1 inhibition targets anti-PD1-resistant lung tumors by blocking myeloid-derived suppressor cells. Cancer Lett. 2018;431:54-63 pubmed 出版商
Peltzer N, Darding M, Montinaro A, Dráber P, Draberova H, Kupka S, et al. LUBAC is essential for embryogenesis by preventing cell death and enabling haematopoiesis. Nature. 2018;557:112-117 pubmed 出版商
Draijer C, Robbe P, Boorsma C, Hylkema M, Melgert B. Dual role of YM1+ M2 macrophages in allergic lung inflammation. Sci Rep. 2018;8:5105 pubmed 出版商
Zhao L, Wang W, Huang S, Yang Z, Xu L, Yang Q, et al. The RNA binding protein SORBS2 suppresses metastatic colonization of ovarian cancer by stabilizing tumor-suppressive immunomodulatory transcripts. Genome Biol. 2018;19:35 pubmed 出版商
Hirata Y, Furuhashi K, Ishii H, Li H, Pinho S, Ding L, et al. CD150high Bone Marrow Tregs Maintain Hematopoietic Stem Cell Quiescence and Immune Privilege via Adenosine. Cell Stem Cell. 2018;22:445-453.e5 pubmed 出版商
Syed I, Lee J, Moraes Vieira P, Donaldson C, Sontheimer A, Aryal P, et al. Palmitic Acid Hydroxystearic Acids Activate GPR40, Which Is Involved in Their Beneficial Effects on Glucose Homeostasis. Cell Metab. 2018;27:419-427.e4 pubmed 出版商
Bussières Marmen S, Vinette V, Gungabeesoon J, Aubry I, Pérez Quintero L, Tremblay M. Loss of T-cell protein tyrosine phosphatase in the intestinal epithelium promotes local inflammation by increasing colonic stem cell proliferation. Cell Mol Immunol. 2018;15:367-376 pubmed 出版商
Han X, Xue X, Zhao Y, Li Y, Liu W, Zhang J, et al. Rutin-Enriched Extract from Coriandrum sativum L. Ameliorates Ionizing Radiation-Induced Hematopoietic Injury. Int J Mol Sci. 2017;18: pubmed 出版商
Hartwig T, Montinaro A, von Karstedt S, Sevko A, Surinova S, Chakravarthy A, et al. The TRAIL-Induced Cancer Secretome Promotes a Tumor-Supportive Immune Microenvironment via CCR2. Mol Cell. 2017;65:730-742.e5 pubmed 出版商
Bignami F, Lorusso A, Rama P, Ferrari G. Growth inhibition of formed corneal neovascularization following Fosaprepitant treatment. Acta Ophthalmol. 2017;95:e641-e648 pubmed 出版商
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Madsen P, Clausen B, Degn M, Thyssen S, Kristensen L, Svensson M, et al. Genetic ablation of soluble tumor necrosis factor with preservation of membrane tumor necrosis factor is associated with neuroprotection after focal cerebral ischemia. J Cereb Blood Flow Metab. 2016;36:1553-69 pubmed 出版商
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Gritsina G, Xiao F, O Brien S, Gabbasov R, Maglaty M, Xu R, et al. Targeted Blockade of JAK/STAT3 Signaling Inhibits Ovarian Carcinoma Growth. Mol Cancer Ther. 2015;14:1035-47 pubmed 出版商
Davis M, Eastman A, Qiu Y, Gregorka B, Kozel T, Osterholzer J, et al. Cryptococcus neoformans-induced macrophage lysosome damage crucially contributes to fungal virulence. J Immunol. 2015;194:2219-31 pubmed 出版商
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产品信息
抗原 :
Ly-6G Ly-6C
Apps. Abbrev. :
流式细胞仪
目录 :
108416
克隆 :
RB6-8C5
产品 :
PE/Cyanine7 anti-mouse Ly-6G/Ly-6C (Gr-1)
抗体亚型 :
Rat IgG2b, κ
其他名称 :
Gr-1
规格 :
100微克
价格(美元) :
180美元
反应物种 :
小鼠
克隆性 :
单克隆
宿主 :
大鼠
共轭标签/标签/标记 :
PE_CYANINE7
免疫原 :
Raised against granulocytes of mouse origin
应用注释 :
Clone RB6-8C5 binds with high affinity to mouse Ly-6G molecules and to a lower extent to Ly-6C 19 . Clone RB6-8C5 impairs the binding of anti-mouse Ly-6G clone 1A8 19 . However, clone RB6-8C5 is able to stain in the presence of anti-mouse Ly-6C clone HK1.4 20 . The RB6-8C5 antibody has been used to identify peripheral blood neutrophils and deplete granulocytes in vivo . Additional reported applications (for relevant formats of this clone) include: in vitro complement-mediated cytotoxicity 2 , in vivo depletion 3-5,9 , immunoprecipitation 1 , immunohistochemical staining 6 (including paraffin-embedded sections 9,16,33-35 , acetone-fixed frozen sections 11 and zinc-fixed sections 15 ), and Western blotting 7 . RB6-8C5 is not suitable for depletion of hepatic myeloid derived suppressor cells (MDSCs) 20 . Special Note: For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 108436).
更多信息或购买 :
公司信息
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品,旨在加速生命科学领域的研发工作。