产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
PerCP/Cyanine5.5 anti-mouse Ly-6G/Ly-6C (Gr-1)
目录 :
108428
规格 :
100微克
价格 :
205美元
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
PerCP/Cy5.5
克隆名称 :
RB6-8C5
反应物种 :
小鼠
应用 :
流式细胞仪
更多信息或购买 :
BioLegend 产品网页
文章摘录数: 25
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 图 5
Vela Ramirez J, Goodman J, Boggiatto P, Roychoudhury R, Pohl N, Hostetter J, et al. Safety and biocompatibility of carbohydrate-functionalized polyanhydride nanoparticles. AAPS J. 2015;17:256-67 pubmed 出版商
  • 流式细胞仪; 小鼠
Kent D, Li J, Tanna H, Fink J, Kirschner K, Pask D, et al. Self-renewal of single mouse hematopoietic stem cells is reduced by JAK2V617F without compromising progenitor cell expansion. PLoS Biol. 2013;11:e1001576 pubmed 出版商
Schmidleithner L, Thabet Y, Schönfeld E, Köhne M, Sommer D, Abdullah Z, et al. Enzymatic Activity of HPGD in Treg Cells Suppresses Tconv Cells to Maintain Adipose Tissue Homeostasis and Prevent Metabolic Dysfunction. Immunity. 2019;50:1232-1248.e14 pubmed 出版商
Luo H, Mu W, Karki R, Chiang H, Mohrin M, Shin J, et al. Mitochondrial Stress-Initiated Aberrant Activation of the NLRP3 Inflammasome Regulates the Functional Deterioration of Hematopoietic Stem Cell Aging. Cell Rep. 2019;26:945-954.e4 pubmed 出版商
Nakamura Ishizu A, Matsumura T, Stumpf P, Umemoto T, Takizawa H, Takihara Y, et al. Thrombopoietin Metabolically Primes Hematopoietic Stem Cells to Megakaryocyte-Lineage Differentiation. Cell Rep. 2018;25:1772-1785.e6 pubmed 出版商
Giambra V, Gusscott S, Gracias D, Song R, Lam S, Panelli P, et al. Epigenetic Restoration of Fetal-like IGF1 Signaling Inhibits Leukemia Stem Cell Activity. Cell Stem Cell. 2018;23:714-726.e7 pubmed 出版商
Winter C, Silvestre Roig C, Ortega Gomez A, Lemnitzer P, Poelman H, Schumski A, et al. Chrono-pharmacological Targeting of the CCL2-CCR2 Axis Ameliorates Atherosclerosis. Cell Metab. 2018;28:175-182.e5 pubmed 出版商
Petriello M, Brandon J, Hoffman J, Wang C, Tripathi H, Abdel Latif A, et al. Dioxin-like PCB 126 increases systemic inflammation and accelerates atherosclerosis in lean LDL receptor deficient mice. Toxicol Sci. 2017;: pubmed 出版商
Chen X, Deng H, Churchill M, Luchsinger L, Du X, Chu T, et al. Bone Marrow Myeloid Cells Regulate Myeloid-Biased Hematopoietic Stem Cells via a Histamine-Dependent Feedback Loop. Cell Stem Cell. 2017;21:747-760.e7 pubmed 出版商
Hönes J, Thivakaran A, Botezatu L, Patnana P, Castro S, Al Matary Y, et al. Enforced GFI1 expression impedes human and murine leukemic cell growth. Sci Rep. 2017;7:15720 pubmed 出版商
Arcipowski K, Bulic M, Gurbuxani S, Licht J. Loss of Mll3 Catalytic Function Promotes Aberrant Myelopoiesis. PLoS ONE. 2016;11:e0162515 pubmed 出版商
Matsushita N, Suzuki M, Ikebe E, Nagashima S, Inatome R, Asano K, et al. Regulation of B cell differentiation by the ubiquitin-binding protein TAX1BP1. Sci Rep. 2016;6:31266 pubmed 出版商
Guo H, Cooper S, Friedman A. In Vivo Deletion of the Cebpa +37 kb Enhancer Markedly Reduces Cebpa mRNA in Myeloid Progenitors but Not in Non-Hematopoietic Tissues to Impair Granulopoiesis. PLoS ONE. 2016;11:e0150809 pubmed 出版商
Däbritz J, Judd L, Chalinor H, Menheniott T, Giraud A. Altered gp130 signalling ameliorates experimental colitis via myeloid cell-specific STAT3 activation and myeloid-derived suppressor cells. Sci Rep. 2016;6:20584 pubmed 出版商
Richardson E, Shukla S, Nagy N, Boom W, Beck R, Zhou L, et al. ERK Signaling Is Essential for Macrophage Development. PLoS ONE. 2015;10:e0140064 pubmed 出版商
Li L, Zhang T, Diao W, Jin F, Shi L, Meng J, et al. Role of Myeloid-Derived Suppressor Cells in Glucocorticoid-Mediated Amelioration of FSGS. J Am Soc Nephrol. 2015;26:2183-97 pubmed 出版商
Garcia Bonilla L, Moore J, Racchumi G, Zhou P, Butler J, Iadecola C, et al. Inducible nitric oxide synthase in neutrophils and endothelium contributes to ischemic brain injury in mice. J Immunol. 2014;193:2531-7 pubmed 出版商
Li L, Zhang J, Diao W, Wang D, Wei Y, Zhang C, et al. MicroRNA-155 and MicroRNA-21 promote the expansion of functional myeloid-derived suppressor cells. J Immunol. 2014;192:1034-43 pubmed 出版商
Mishra A, Alves J, Krumbach K, Nigou J, Castro A, Geurtsen J, et al. Differential arabinan capping of lipoarabinomannan modulates innate immune responses and impacts T helper cell differentiation. J Biol Chem. 2012;287:44173-83 pubmed 出版商
Haka A, Potteaux S, Fraser H, Randolph G, Maxfield F. Quantitative analysis of monocyte subpopulations in murine atherosclerotic plaques by multiphoton microscopy. PLoS ONE. 2012;7:e44823 pubmed
Piao Y, Liang J, Holmes L, Zurita A, Henry V, Heymach J, et al. Glioblastoma resistance to anti-VEGF therapy is associated with myeloid cell infiltration, stem cell accumulation, and a mesenchymal phenotype. Neuro Oncol. 2012;14:1379-92 pubmed 出版商
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产品信息
抗原 :
Ly-6G Ly-6C
Apps. Abbrev. :
流式细胞仪
目录 :
108428
克隆 :
RB6-8C5
产品 :
PerCP/Cyanine5.5 anti-mouse Ly-6G/Ly-6C (Gr-1)
抗体亚型 :
Rat IgG2b, κ
其他名称 :
Gr-1
规格 :
100微克
价格(美元) :
205美元
反应物种 :
小鼠
克隆性 :
单克隆
宿主 :
大鼠
共轭标签/标签/标记 :
PERCP_CYANINE5.5
免疫原 :
Raised against granulocytes of mouse origin
应用注释 :
Clone RB6-8C5 binds with high affinity to mouse Ly-6G molecules and to a lower extent to Ly-6C 19 . Clone RB6-8C5 impairs the binding of anti-mouse Ly-6G clone 1A8 19 . However, clone RB6-8C5 is able to stain in the presence of anti-mouse Ly-6C clone HK1.4 20 . The RB6-8C5 antibody has been used to identify peripheral blood neutrophils and deplete granulocytes in vivo . Additional reported applications (for relevant formats of this clone) include: in vitro complement-mediated cytotoxicity 2 , in vivo depletion 3-5,9 , immunoprecipitation 1 , immunohistochemical staining 6 (including paraffin-embedded sections 9,16,33-35 , acetone-fixed frozen sections 11 and zinc-fixed sections 15 ), and Western blotting 7 . RB6-8C5 is not suitable for depletion of hepatic myeloid derived suppressor cells (MDSCs) 20 . Special Note: For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 108436).
更多信息或购买 :
BioLegend 产品网页
公司信息
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品，旨在加速生命科学领域的研发工作。