Wu S, Fukumoto T, Lin J, Nacarelli T, Wang Y, Ong D, et al. Targeting glutamine dependence through GLS1 inhibition suppresses ARID1A-inactivated clear cell ovarian carcinoma. Nat Cancer. 2021;2:189-200 pubmed 出版商

Webb L, Fra Bido S, Innocentin S, Matheson L, Attaf N, Bignon A, et al. Ageing promotes early T follicular helper cell differentiation by modulating expression of RBPJ. Aging Cell. 2021;20:e13295 pubmed 出版商

Chen Z, Ji Z, Ngiow S, Manne S, Cai Z, Huang A, et al. TCF-1-Centered Transcriptional Network Drives an Effector versus Exhausted CD8 T Cell-Fate Decision. Immunity. 2019;51:840-855.e5 pubmed 出版商

Koike T, Harada K, Horiuchi S, Kitamura D. The quantity of CD40 signaling determines the differentiation of B cells into functionally distinct memory cell subsets. elife. 2019;8: pubmed 出版商

Cox M, Duncan G, Lin G, Steinberg B, Yu L, Brenner D, et al. Choline acetyltransferase-expressing T cells are required to control chronic viral infection. Science. 2019;363:639-644 pubmed 出版商

Hu Y, Kim J, He K, Wan Q, Kim J, Flach M, et al. Scramblase TMEM16F terminates T cell receptor signaling to restrict T cell exhaustion. J Exp Med. 2016;213:2759-2772 pubmed

Zotos D, Quast I, Li Wai Suen C, McKenzie C, Robinson M, Kan A, et al. The concerted change in the distribution of cell cycle phases and zone composition in germinal centers is regulated by IL-21. Nat Commun. 2021;12:7160 pubmed 出版商

Alameh M, Tombácz I, Bettini E, Lederer K, Sittplangkoon C, Wilmore J, et al. Lipid nanoparticles enhance the efficacy of mRNA and protein subunit vaccines by inducing robust T follicular helper cell and humoral responses. Immunity. 2021;54:2877-2892.e7 pubmed 出版商

Stump C, Roehle K, Manjarrez Orduno N, Dougan S. Radiation combines with immune checkpoint blockade to enhance T cell priming in a murine model of poorly immunogenic pancreatic cancer. Open Biol. 2021;11:210245 pubmed 出版商

Montes De Oca R, Alavi A, Vitali N, Bhattacharya S, Blackwell C, Patel K, et al. Belantamab Mafodotin (GSK2857916) Drives Immunogenic Cell Death and Immune-mediated Antitumor Responses In Vivo. Mol Cancer Ther. 2021;20:1941-1955 pubmed 出版商

Fu G, Guy C, Chapman N, Palacios G, Wei J, Zhou P, et al. Metabolic control of TFH cells and humoral immunity by phosphatidylethanolamine. Nature. 2021;595:724-729 pubmed 出版商

Xu C, Sun S, Johnson T, Qi R, Zhang S, Zhang J, et al. The glutathione peroxidase Gpx4 prevents lipid peroxidation and ferroptosis to sustain Treg cell activation and suppression of antitumor immunity. Cell Rep. 2021;35:109235 pubmed 出版商

Volberding P, Xin G, Kasmani M, Khatun A, Brown A, Nguyen C, et al. Suppressive neutrophils require PIM1 for metabolic fitness and survival during chronic viral infection. Cell Rep. 2021;35:109160 pubmed 出版商

McLane L, Ngiow S, Chen Z, Attanasio J, Manne S, Ruthel G, et al. Role of nuclear localization in the regulation and function of T-bet and Eomes in exhausted CD8 T cells. Cell Rep. 2021;35:109120 pubmed 出版商

Gern B, Adams K, Plumlee C, Stoltzfus C, Shehata L, Moguche A, et al. TGFβ restricts expansion, survival, and function of T cells within the tuberculous granuloma. Cell Host Microbe. 2021;29:594-606.e6 pubmed 出版商

Chen Z, Arai E, Khan O, Zhang Z, Ngiow S, He Y, et al. In vivo CD8+ T cell CRISPR screening reveals control by Fli1 in infection and cancer. Cell. 2021;184:1262-1280.e22 pubmed 出版商

Trefzer A, Kadam P, Wang S, Pennavaria S, Lober B, Akçabozan B, et al. Dynamic adoption of anergy by antigen-exhausted CD4+ T cells. Cell Rep. 2021;34:108748 pubmed 出版商

Dubrot J, Lane Reticker S, Kessler E, Ayer A, Mishra G, Wolfe C, et al. In vivo screens using a selective CRISPR antigen removal lentiviral vector system reveal immune dependencies in renal cell carcinoma. Immunity. 2021;: pubmed 出版商

Suah A, Tran D, Khiew S, Andrade M, Pollard J, Jain D, et al. Pregnancy-induced humoral sensitization overrides T cell tolerance to fetus-matched allografts in mice. J Clin Invest. 2021;131: pubmed 出版商

Ringel A, Drijvers J, Baker G, Catozzi A, García Cañaveras J, Gassaway B, et al. Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity. Cell. 2020;183:1848-1866.e26 pubmed 出版商

Lederer K, Castaño D, Gomez Atria D, Oguin T, Wang S, Manzoni T, et al. SARS-CoV-2 mRNA Vaccines Foster Potent Antigen-Specific Germinal Center Responses Associated with Neutralizing Antibody Generation. Immunity. 2020;53:1281-1295.e5 pubmed 出版商

Acharya N, Madi A, Zhang H, Klapholz M, Escobar G, Dulberg S, et al. Endogenous Glucocorticoid Signaling Regulates CD8+ T Cell Differentiation and Development of Dysfunction in the Tumor Microenvironment. Immunity. 2020;53:658-671.e6 pubmed 出版商

Xiao S, Bod L, Pochet N, KOTA S, Hu D, Madi A, et al. Checkpoint Receptor TIGIT Expressed on Tim-1+ B Cells Regulates Tissue Inflammation. Cell Rep. 2020;32:107892 pubmed 出版商

Vardhana S, Hwee M, Berisa M, Wells D, Yost K, King B, et al. Impaired mitochondrial oxidative phosphorylation limits the self-renewal of T cells exposed to persistent antigen. Nat Immunol. 2020;: pubmed 出版商

Evgin L, Huff A, Wongthida P, Thompson J, Kottke T, Tonne J, et al. Oncolytic virus-derived type I interferon restricts CAR T cell therapy. Nat Commun. 2020;11:3187 pubmed 出版商

Jing Y, Dai X, Yang L, Kang D, Jiang P, Li N, et al. STING couples with PI3K to regulate actin reorganization during BCR activation. Sci Adv. 2020;6:eaax9455 pubmed 出版商

Biram A, Winter E, Denton A, Zaretsky I, Dassa B, Bemark M, et al. B Cell Diversification Is Uncoupled from SAP-Mediated Selection Forces in Chronic Germinal Centers within Peyer's Patches. Cell Rep. 2020;30:1910-1922.e5 pubmed 出版商

Sullivan J, Tomita Y, Jankowska Gan E, Lema D, Arvedson M, Nair A, et al. Treg-Cell-Derived IL-35-Coated Extracellular Vesicles Promote Infectious Tolerance. Cell Rep. 2020;30:1039-1051.e5 pubmed 出版商

Vanderleyden I, Fra Bido S, Innocentin S, Stebegg M, Okkenhaug H, Evans Bailey N, et al. Follicular Regulatory T Cells Can Access the Germinal Center Independently of CXCR5. Cell Rep. 2020;30:611-619.e4 pubmed 出版商

Zander R, SCHAUDER D, Xin G, Nguyen C, Wu X, ZAJAC A, et al. CD4+ T Cell Help Is Required for the Formation of a Cytolytic CD8+ T Cell Subset that Protects against Chronic Infection and Cancer. Immunity. 2019;51:1028-1042.e4 pubmed 出版商

Elsner R, Shlomchik M. IL-12 Blocks Tfh Cell Differentiation during Salmonella Infection, thereby Contributing to Germinal Center Suppression. Cell Rep. 2019;29:2796-2809.e5 pubmed 出版商

Hilpert C, Sitte S, Arnold H, Lehmann C, Dudziak D, Mattner J, et al. Dendritic Cells Control Regulatory T Cell Function Required for Maintenance of Intestinal Tissue Homeostasis. J Immunol. 2019;203:3068-3077 pubmed 出版商

Yadava K, Medina C, Ishak H, Gurevich I, Kuipers H, Shamskhou E, et al. Natural Tr1-like cells do not confer long-term tolerogenic memory. elife. 2019;8: pubmed 出版商

Filskov J, Andersen P, Agger E, Bukh J. HCV p7 as a novel vaccine-target inducing multifunctional CD4+ and CD8+ T-cells targeting liver cells expressing the viral antigen. Sci Rep. 2019;9:14085 pubmed 出版商

Benci J, Johnson L, Choa R, Xu Y, Qiu J, Zhou Z, et al. Opposing Functions of Interferon Coordinate Adaptive and Innate Immune Responses to Cancer Immune Checkpoint Blockade. Cell. 2019;178:933-948.e14 pubmed 出版商

Etzerodt A, Tsalkitzi K, Maniecki M, Damsky W, Delfini M, Baudoin E, et al. Specific targeting of CD163+ TAMs mobilizes inflammatory monocytes and promotes T cell-mediated tumor regression. J Exp Med. 2019;216:2394-2411 pubmed 出版商

Myers D, Norlin E, Vercoulen Y, Roose J. Active Tonic mTORC1 Signals Shape Baseline Translation in Naive T Cells. Cell Rep. 2019;27:1858-1874.e6 pubmed 出版商

Blecher Gonen R, Bost P, Hilligan K, David E, Salame T, Roussel E, et al. Single-Cell Analysis of Diverse Pathogen Responses Defines a Molecular Roadmap for Generating Antigen-Specific Immunity. Cell Syst. 2019;8:109-121.e6 pubmed 出版商

Jin C, Lagoudas G, Zhao C, Bullman S, Bhutkar A, Hu B, et al. Commensal Microbiota Promote Lung Cancer Development via γδ T Cells. Cell. 2019;176:998-1013.e16 pubmed 出版商

Van Gool F, Nguyen M, Mumbach M, Satpathy A, Rosenthal W, Giacometti S, et al. A Mutation in the Transcription Factor Foxp3 Drives T Helper 2 Effector Function in Regulatory T Cells. Immunity. 2019;50:362-377.e6 pubmed 出版商

Siddiqui I, Schaeuble K, Chennupati V, Fuertes Marraco S, Calderon Copete S, Pais Ferreira D, et al. Intratumoral Tcf1+PD-1+CD8+ T Cells with Stem-like Properties Promote Tumor Control in Response to Vaccination and Checkpoint Blockade Immunotherapy. Immunity. 2019;50:195-211.e10 pubmed 出版商

Kurtulus S, Madi A, Escobar G, Klapholz M, Nyman J, Christian E, et al. Checkpoint Blockade Immunotherapy Induces Dynamic Changes in PD-1-CD8+ Tumor-Infiltrating T Cells. Immunity. 2019;50:181-194.e6 pubmed 出版商

Verghese D, Chun N, Paz K, Fribourg M, Woodruff T, Flynn R, et al. C5aR1 regulates T follicular helper differentiation and chronic graft-versus-host disease bronchiolitis obliterans. JCI Insight. 2018;3: pubmed 出版商

Jain R, Parham K, Tesfagiorgis Y, Craig H, Romanchik E, Kerfoot S. Autoreactive, Low-Affinity T Cells Preferentially Drive Differentiation of Short-Lived Memory B Cells at the Expense of Germinal Center Maintenance. Cell Rep. 2018;25:3342-3355.e5 pubmed 出版商

Turner J, Ke F, GRIGOROVA I. B Cell Receptor Crosslinking Augments Germinal Center B Cell Selection when T Cell Help Is Limiting. Cell Rep. 2018;25:1395-1403.e4 pubmed 出版商

Fan M, Low J, Tanimine N, Finn K, Priyadharshini B, Germana S, et al. Differential Roles of IL-2 Signaling in Developing versus Mature Tregs. Cell Rep. 2018;25:1204-1213.e4 pubmed 出版商

Shi J, Hou S, Fang Q, Liu X, Liu X, Qi H. PD-1 Controls Follicular T Helper Cell Positioning and Function. Immunity. 2018;49:264-274.e4 pubmed 出版商

Hossain D, Javaid S, Cai M, Zhang C, Sawant A, Hinton M, et al. Dinaciclib induces immunogenic cell death and enhances anti-PD1-mediated tumor suppression. J Clin Invest. 2018;128:644-654 pubmed 出版商

Chatterjee S, Daenthanasanmak A, Chakraborty P, Wyatt M, Dhar P, Selvam S, et al. CD38-NAD+Axis Regulates Immunotherapeutic Anti-Tumor T Cell Response. Cell Metab. 2018;27:85-100.e8 pubmed 出版商

Zhang Y, Kurupati R, Liu L, Zhou X, Zhang G, Hudaihed A, et al. Enhancing CD8+ T Cell Fatty Acid Catabolism within a Metabolically Challenging Tumor Microenvironment Increases the Efficacy of Melanoma Immunotherapy. Cancer Cell. 2017;32:377-391.e9 pubmed 出版商

Perez Mazliah D, Nguyen M, Hosking C, McLaughlin S, Lewis M, Tumwine I, et al. Follicular Helper T Cells are Essential for the Elimination of Plasmodium Infection. EBioMedicine. 2017;24:216-230 pubmed 出版商

Nawaf M, Ulvmar M, Withers D, McConnell F, Gaspal F, Webb G, et al. Concurrent OX40 and CD30 Ligand Blockade Abrogates the CD4-Driven Autoimmunity Associated with CTLA4 and PD1 Blockade while Preserving Excellent Anti-CD8 Tumor Immunity. J Immunol. 2017;199:974-981 pubmed 出版商

Benci J, Xu B, Qiu Y, Wu T, Dada H, Twyman Saint Victor C, et al. Tumor Interferon Signaling Regulates a Multigenic Resistance Program to Immune Checkpoint Blockade. Cell. 2016;167:1540-1554.e12 pubmed 出版商

Tuero I, Venzon D, Robert Guroff M. Mucosal and Systemic γδ+ T Cells Associated with Control of Simian Immunodeficiency Virus Infection. J Immunol. 2016;197:4686-4695 pubmed

Miyauchi K, Sugimoto Ishige A, Harada Y, Adachi Y, Usami Y, Kaji T, et al. Protective neutralizing influenza antibody response in the absence of T follicular helper cells. Nat Immunol. 2016;17:1447-1458 pubmed 出版商

Singer M, Wang C, Cong L, Marjanovic N, Kowalczyk M, Zhang H, et al. A Distinct Gene Module for Dysfunction Uncoupled from Activation in Tumor-Infiltrating T Cells. Cell. 2016;166:1500-1511.e9 pubmed 出版商

Hilpert C, Sitte S, Matthies A, Voehringer D. Dendritic Cells Are Dispensable for T Cell Priming and Control of Acute Lymphocytic Choriomeningitis Virus Infection. J Immunol. 2016;197:2780-6 pubmed 出版商

Christensen D, Mortensen R, Rosenkrands I, Dietrich J, Andersen P. Vaccine-induced Th17 cells are established as resident memory cells in the lung and promote local IgA responses. Mucosal Immunol. 2017;10:260-270 pubmed 出版商

Woodworth J, Aagaard C, Hansen P, Cassidy J, Agger E, Andersen P. Protective CD4 T cells targeting cryptic epitopes of Mycobacterium tuberculosis resist infection-driven terminal differentiation. J Immunol. 2014;192:3247-58 pubmed 出版商

McPhee C, Bubier J, Sproule T, Park G, Steinbuck M, Schott W, et al. IL-21 is a double-edged sword in the systemic lupus erythematosus-like disease of BXSB.Yaa mice. J Immunol. 2013;191:4581-8 pubmed 出版商

Lindenstrøm T, Knudsen N, Agger E, Andersen P. Control of chronic mycobacterium tuberculosis infection by CD4 KLRG1- IL-2-secreting central memory cells. J Immunol. 2013;190:6311-9 pubmed 出版商

Jeon S, St Leger A, Cherpes T, Sheridan B, Hendricks R. PD-L1/B7-H1 regulates the survival but not the function of CD8+ T cells in herpes simplex virus type 1 latently infected trigeminal ganglia. J Immunol. 2013;190:6277-86 pubmed 出版商

King I, Mohrs M. IL-4-producing CD4+ T cells in reactive lymph nodes during helminth infection are T follicular helper cells. J Exp Med. 2009;206:1001-7 pubmed 出版商

Raimondi G, Shufesky W, Tokita D, Morelli A, Thomson A. Regulated compartmentalization of programmed cell death-1 discriminates CD4+CD25+ resting regulatory T cells from activated T cells. J Immunol. 2006;176:2808-16 pubmed