产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
Alexa Fluor® 647 anti-mouse TCR β chain
目录 :
109217
规格 :
25微克
价格 :
85美元
克隆性 :
单克隆
宿主 :
仓鼠
共轭标签 :
AF647
克隆名称 :
H57-597
反应物种 :
人类, 小鼠
应用 :
免疫细胞化学, 流式细胞仪, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 84
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 图 4a
Qian L, Bajana S, Georgescu C, Peng V, Wang H, Adrianto I, et al. Suppression of ILC2 differentiation from committed T cell precursors by E protein transcription factors. J Exp Med. 2019;216:884-899 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1e, e1b, e3b
Karmaus P, Chen X, Lim S, Herrada A, Nguyen T, Xu B, et al. Metabolic heterogeneity underlies reciprocal fates of TH17 cell stemness and plasticity. Nature. 2019;565:101-105 pubmed 出版商
  • 流式细胞仪; 人类; 图 1d
Poncette L, Chen X, Lorenz F, Blankenstein T. Effective NY-ESO-1-specific MHC II-restricted T cell receptors from antigen-negative hosts enhance tumor regression. J Clin Invest. 2019;129:324-335 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5d
Vuckovic S, Minnie S, Smith D, Gartlan K, Watkins T, Markey K, et al. Bone marrow transplantation generates T cell-dependent control of myeloma in mice. J Clin Invest. 2019;129:106-121 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s3
Sato Y, Bolzenius J, Eteleeb A, Su X, Maher C, Sehn J, et al. CD4+ T cells induce rejection of urothelial tumors after immune checkpoint blockade. JCI Insight. 2018;3: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1a, 2c
Atretkhany K, Mufazalov I, Dunst J, Kuchmiy A, Gogoleva V, Andruszewski D, et al. Intrinsic TNFR2 signaling in T regulatory cells provides protection in CNS autoimmunity. Proc Natl Acad Sci U S A. 2018;115:13051-13056 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4f
James K, Cosway E, LUCAS B, White A, Parnell S, Carvalho Gaspar M, et al. Endothelial cells act as gatekeepers for LTβR-dependent thymocyte emigration. J Exp Med. 2018;215:2984-2993 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 4g
Lin Y, Pecetta S, Steichen J, Kratochvil S, Melzi E, Arnold J, et al. One-step CRISPR/Cas9 method for the rapid generation of human antibody heavy chain knock-in mice. EMBO J. 2018;37: pubmed 出版商
  • 免疫细胞化学; 人类; 图 5a
Zhao Y, Harrison D, Song Y, Ji J, Huang J, Hui E. Antigen-Presenting Cell-Intrinsic PD-1 Neutralizes PD-L1 in cis to Attenuate PD-1 Signaling in T Cells. Cell Rep. 2018;24:379-390.e6 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3g
Jun H, Yu H, Gong J, Jiang J, Qiao X, Perkey E, et al. An immune-beige adipocyte communication via nicotinic acetylcholine receptor signaling. Nat Med. 2018;24:814-822 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:200; 图 s5d
Huynh J, Lin C, Kimmey J, Jarjour N, Schwarzkopf E, Bradstreet T, et al. Bhlhe40 is an essential repressor of IL-10 during Mycobacterium tuberculosis infection. J Exp Med. 2018;215:1823-1838 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2
Chorazeczewski J, Aleshnick M, Majam V, Okoth W, Kurapova R, Akue A, et al. TCRβ Combinatorial Immunoreceptor Expression by Neutrophils Correlates with Parasite Burden and Enhanced Phagocytosis during a Plasmodium berghei ANKA Malaria Infection. Infect Immun. 2018;86: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s12a
Sui P, Wiesner D, Xu J, Zhang Y, Lee J, Van Dyken S, et al. Pulmonary neuroendocrine cells amplify allergic asthma responses. Science. 2018;360: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4a
Trapecar M, Khan S, Cohn B, Wu F, Sanjabi S. B cells are the predominant mediators of early systemic viral dissemination during rectal LCMV infection. Mucosal Immunol. 2018;11:1158-1167 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5d
Koh A, Miller E, Buenrostro J, Moskowitz D, Wang J, Greenleaf W, et al. Rapid chromatin repression by Aire provides precise control of immune tolerance. Nat Immunol. 2018;19:162-172 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1b
Yu H, Gagliani N, Ishigame H, Huber S, Zhu S, Esplugues E, et al. Intestinal type 1 regulatory T cells migrate to periphery to suppress diabetogenic T cells and prevent diabetes development. Proc Natl Acad Sci U S A. 2017;114:10443-10448 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2e
Rowe A, Yun H, Treat B, Kinchington P, Hendricks R. Subclinical Herpes Simplex Virus Type 1 Infections Provide Site-Specific Resistance to an Unrelated Pathogen. J Immunol. 2017;198:1706-1717 pubmed 出版商
Zhu W, Naler L, Maul R, Sallin M, Sen J. Immune system development and age-dependent maintenance in Klotho-hypomorphic mice. Aging (Albany NY). 2019;11:5246-5257 pubmed 出版商
Pascutti M, Geerman S, Collins N, Brasser G, Nota B, Stark R, et al. Peripheral and systemic antigens elicit an expandable pool of resident memory CD8+ T cells in the bone marrow. Eur J Immunol. 2019;49:853-872 pubmed 出版商
Kimura S, Kobayashi N, Nakamura Y, Kanaya T, Takahashi D, Fujiki R, et al. Sox8 is essential for M cell maturation to accelerate IgA response at the early stage after weaning in mice. J Exp Med. 2019;216:831-846 pubmed 出版商
Klein F, Mitrovic M, Roux J, Engdahl C, von Muenchow L, Albertí Servera L, et al. The transcription factor Duxbl mediates elimination of pre-T cells that fail β-selection. J Exp Med. 2019;216:638-655 pubmed 出版商
Silva D, Yu S, Ulge U, Spangler J, Jude K, Labao Almeida C, et al. De novo design of potent and selective mimics of IL-2 and IL-15. Nature. 2019;565:186-191 pubmed 出版商
Salou M, Legoux F, Gilet J, Darbois A, du Halgouet A, Alonso R, et al. A common transcriptomic program acquired in the thymus defines tissue residency of MAIT and NKT subsets. J Exp Med. 2019;216:133-151 pubmed 出版商
Huang L, Zinselmeyer B, Chang C, Saunders B, Elvington A, Baba O, et al. Interleukin-17 Drives Interstitial Entrapment of Tissue Lipoproteins in Experimental Psoriasis. Cell Metab. 2019;29:475-487.e7 pubmed 出版商
Diercks B, Werner R, Weidemüller P, Czarniak F, Hernandez L, Lehmann C, et al. ORAI1, STIM1/2, and RYR1 shape subsecond Ca2+ microdomains upon T cell activation. Sci Signal. 2018;11: pubmed 出版商
Ding L, Kim H, Wang Q, Kearns M, Jiang T, Ohlson C, et al. PARP Inhibition Elicits STING-Dependent Antitumor Immunity in Brca1-Deficient Ovarian Cancer. Cell Rep. 2018;25:2972-2980.e5 pubmed 出版商
Edwards C, de Oca M, de Labastida Rivera F, Kumar R, Ng S, Wang Y, et al. The Role of BACH2 in T Cells in Experimental Malaria Caused by Plasmodium chabaudi chabaudi AS. Front Immunol. 2018;9:2578 pubmed 出版商
Sandrock I, Reinhardt A, Ravens S, Binz C, Wilharm A, Martins J, et al. Genetic models reveal origin, persistence and non-redundant functions of IL-17-producing γδ T cells. J Exp Med. 2018;215:3006-3018 pubmed 出版商
Movahed E, Cheok Y, Tan G, Lee C, Cheong H, Velayuthan R, et al. Lung-infiltrating T helper 17 cells as the major source of interleukin-17A production during pulmonary Cryptococcus neoformans infection. BMC Immunol. 2018;19:32 pubmed 出版商
Ogawa C, Bankoti R, Nguyen T, Hassanzadeh Kiabi N, Nadeau S, Porritt R, et al. Blimp-1 Functions as a Molecular Switch to Prevent Inflammatory Activity in Foxp3+RORγt+ Regulatory T Cells. Cell Rep. 2018;25:19-28.e5 pubmed 出版商
Hansell C, Fraser A, Hayes A, Pingen M, Burt C, Lee K, et al. The Atypical Chemokine Receptor Ackr2 Constrains NK Cell Migratory Activity and Promotes Metastasis. J Immunol. 2018;201:2510-2519 pubmed 出版商
Tilstra J, Avery L, Menk A, Gordon R, Smita S, Kane L, et al. Kidney-infiltrating T cells in murine lupus nephritis are metabolically and functionally exhausted. J Clin Invest. 2018;128:4884-4897 pubmed 出版商
Kong X, Martinez Barricarte R, Kennedy J, Mele F, Lazarov T, Deenick E, et al. Disruption of an antimycobacterial circuit between dendritic and helper T cells in human SPPL2a deficiency. Nat Immunol. 2018;19:973-985 pubmed 出版商
Shehata H, Khan S, Chen E, Fields P, Flavell R, Sanjabi S. Lack of Sprouty 1 and 2 enhances survival of effector CD8+ T cells and yields more protective memory cells. Proc Natl Acad Sci U S A. 2018;115:E8939-E8947 pubmed 出版商
Suzuki J, Yamada T, Inoue K, Nabe S, Kuwahara M, Takemori N, et al. The tumor suppressor menin prevents effector CD8 T-cell dysfunction by targeting mTORC1-dependent metabolic activation. Nat Commun. 2018;9:3296 pubmed 出版商
Maurice D, Costello P, Sargent M, Treisman R. ERK Signaling Controls Innate-like CD8+ T Cell Differentiation via the ELK4 (SAP-1) and ELK1 Transcription Factors. J Immunol. 2018;201:1681-1691 pubmed 出版商
Rossboth B, Arnold A, Ta H, Platzer R, Kellner F, Huppa J, et al. TCRs are randomly distributed on the plasma membrane of resting antigen-experienced T cells. Nat Immunol. 2018;19:821-827 pubmed 出版商
Arnold I, Artola Borán M, Tallón de Lara P, Kyburz A, Taube C, OTTEMANN K, et al. Eosinophils suppress Th1 responses and restrict bacterially induced gastrointestinal inflammation. J Exp Med. 2018;215:2055-2072 pubmed 出版商
Manresa Arraut A, Johansen F, Brakebusch C, Issazadeh Navikas S, Hasseldam H. RhoA Drives T-Cell Activation and Encephalitogenic Potential in an Animal Model of Multiple Sclerosis. Front Immunol. 2018;9:1235 pubmed 出版商
Napolitano A, van der Veen A, Bunyan M, Borg A, Frith D, Howell S, et al. Cysteine-Reactive Free ISG15 Generates IL-1β-Producing CD8α+ Dendritic Cells at the Site of Infection. J Immunol. 2018;201:604-614 pubmed 出版商
Wei B, Zhang R, Zhai J, Zhu J, Yang F, Yue D, et al. Suppression of Th17 Cell Response in the Alleviation of Dextran Sulfate Sodium-Induced Colitis by Ganoderma lucidum Polysaccharides. J Immunol Res. 2018;2018:2906494 pubmed 出版商
Shaw T, Houston S, Wemyss K, Bridgeman H, Barbera T, Zangerle Murray T, et al. Tissue-resident macrophages in the intestine are long lived and defined by Tim-4 and CD4 expression. J Exp Med. 2018;215:1507-1518 pubmed 出版商
Pardi N, Hogan M, Naradikian M, Parkhouse K, Cain D, Jones L, et al. Nucleoside-modified mRNA vaccines induce potent T follicular helper and germinal center B cell responses. J Exp Med. 2018;215:1571-1588 pubmed 出版商
Ramani K, Jawale C, Verma A, Coleman B, Kolls J, Biswas P. Unexpected kidney-restricted role for IL-17 receptor signaling in defense against systemic Candida albicans infection. JCI Insight. 2018;3: pubmed 出版商
Treise I, Huber E, Klein Rodewald T, Heinemeyer W, Grassmann S, Basler M, et al. Defective immuno- and thymoproteasome assembly causes severe immunodeficiency. Sci Rep. 2018;8:5975 pubmed 出版商
Kling J, Jordan M, Pitt L, Meiners J, Thanh Tran T, Tran L, et al. Temporal Regulation of Natural Killer T Cell Interferon Gamma Responses by β-Catenin-Dependent and -Independent Wnt Signaling. Front Immunol. 2018;9:483 pubmed 出版商
Jesteadt E, Zhang I, Yu H, Meierovics A, Chua Yankelevich W, Cowley S. Interleukin-18 Is Critical for Mucosa-Associated Invariant T Cell Gamma Interferon Responses to Francisella Species In Vitro but Not In Vivo. Infect Immun. 2018;86: pubmed 出版商
Panduro M, Benoist C, Mathis D. Treg cells limit IFN-? production to control macrophage accrual and phenotype during skeletal muscle regeneration. Proc Natl Acad Sci U S A. 2018;115:E2585-E2593 pubmed 出版商
Brasseit J, Kwong Chung C, Noti M, Zysset D, Hoheisel Dickgreber N, Genitsch V, et al. Divergent Roles of Interferon-γ and Innate Lymphoid Cells in Innate and Adaptive Immune Cell-Mediated Intestinal Inflammation. Front Immunol. 2018;9:23 pubmed 出版商
Xu M, Pokrovskii M, Ding Y, Yi R, Au C, Harrison O, et al. c-MAF-dependent regulatory T cells mediate immunological tolerance to a gut pathobiont. Nature. 2018;554:373-377 pubmed 出版商
Ju J, Jung M, Nam G, Kim W, Oh S, Kim H, et al. Escape from thymic deletion and anti-leukemic effects of T cells specific for hematopoietic cell-restricted antigen. Nat Commun. 2018;9:225 pubmed 出版商
Eichinger K, Kosanovich J, Empey K. Localization of the T-cell response to RSV infection is altered in infant mice. Pediatr Pulmonol. 2017;: pubmed 出版商
Naik S, Larsen S, Gomez N, Alaverdyan K, Sendoel A, Yuan S, et al. Inflammatory memory sensitizes skin epithelial stem cells to tissue damage. Nature. 2017;550:475-480 pubmed 出版商
Roussey J, Viglianti S, Teitz Tennenbaum S, Olszewski M, Osterholzer J. Anti-PD-1 Antibody Treatment Promotes Clearance of Persistent Cryptococcal Lung Infection in Mice. J Immunol. 2017;199:3535-3546 pubmed 出版商
Wallrapp A, Riesenfeld S, Burkett P, Abdulnour R, Nyman J, Dionne D, et al. The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation. Nature. 2017;549:351-356 pubmed 出版商
Gibb D, Liu J, Santhanakrishnan M, Natarajan P, Madrid D, Patel S, et al. B cells require Type 1 interferon to produce alloantibodies to transfused KEL-expressing red blood cells in mice. Transfusion. 2017;57:2595-2608 pubmed 出版商
Cosway E, LUCAS B, James K, Parnell S, Carvalho Gaspar M, White A, et al. Redefining thymus medulla specialization for central tolerance. J Exp Med. 2017;214:3183-3195 pubmed 出版商
Teng F, Felix K, Bradley C, Naskar D, Ma H, Raslan W, et al. The impact of age and gut microbiota on Th17 and Tfh cells in K/BxN autoimmune arthritis. Arthritis Res Ther. 2017;19:188 pubmed 出版商
Nussbaum K, Burkhard S, Ohs I, Mair F, Klose C, Arnold S, et al. Tissue microenvironment dictates the fate and tumor-suppressive function of type 3 ILCs. J Exp Med. 2017;214:2331-2347 pubmed 出版商
Gibb D, Liu J, Natarajan P, Santhanakrishnan M, Madrid D, Eisenbarth S, et al. Type I IFN Is Necessary and Sufficient for Inflammation-Induced Red Blood Cell Alloimmunization in Mice. J Immunol. 2017;199:1041-1050 pubmed 出版商
Parashar K, Kopping E, Frank D, Sampath V, Thanassi D, Carpino N. Increased Resistance to Intradermal Francisella tularensis LVS Infection by Inactivation of the Sts Phosphatases. Infect Immun. 2017;85: pubmed 出版商
Lupfer C, Stokes K, Kuriakose T, Kanneganti T. Deficiency of the NOD-Like Receptor NLRC5 Results in Decreased CD8+ T Cell Function and Impaired Viral Clearance. J Virol. 2017;91: pubmed 出版商
Overacre Delgoffe A, Chikina M, Dadey R, Yano H, Brunazzi E, Shayan G, et al. Interferon-? Drives Treg Fragility to Promote Anti-tumor Immunity. Cell. 2017;169:1130-1141.e11 pubmed 出版商
Seki S, Stevenson M, Rosen A, Arandjelovic S, Gemta L, Bullock T, et al. Lineage-Specific Metabolic Properties and Vulnerabilities of T Cells in the Demyelinating Central Nervous System. J Immunol. 2017;198:4607-4617 pubmed 出版商
Moffitt A, Ondrejka S, McKinney M, Rempel R, Goodlad J, Teh C, et al. Enteropathy-associated T cell lymphoma subtypes are characterized by loss of function of SETD2. J Exp Med. 2017;214:1371-1386 pubmed 出版商
Fu G, Xu Q, Qiu Y, Jin X, Xu T, Dong S, et al. Suppression of Th17 cell differentiation by misshapen/NIK-related kinase MINK1. J Exp Med. 2017;214:1453-1469 pubmed 出版商
Srivatsa S, Paul M, Cardone C, Holcmann M, Amberg N, Pathria P, et al. EGFR in Tumor-Associated Myeloid Cells Promotes Development of Colorectal Cancer in Mice and Associates With Outcomes of Patients. Gastroenterology. 2017;153:178-190.e10 pubmed 出版商
Zemmour D, Pratama A, Loughhead S, Mathis D, Benoist C. Flicr, a long noncoding RNA, modulates Foxp3 expression and autoimmunity. Proc Natl Acad Sci U S A. 2017;114:E3472-E3480 pubmed 出版商
Sindhava V, Oropallo M, Moody K, Naradikian M, Higdon L, Zhou L, et al. A TLR9-dependent checkpoint governs B cell responses to DNA-containing antigens. J Clin Invest. 2017;127:1651-1663 pubmed 出版商
Naskar D, Teng F, Felix K, Bradley C, WU H. Synthetic Retinoid AM80 Ameliorates Lung and Arthritic Autoimmune Responses by Inhibiting T Follicular Helper and Th17 Cell Responses. J Immunol. 2017;198:1855-1864 pubmed 出版商
Levine A, Hemmers S, Baptista A, Schizas M, Faire M, Moltedo B, et al. Suppression of lethal autoimmunity by regulatory T cells with a single TCR specificity. J Exp Med. 2017;214:609-622 pubmed 出版商
Liang D, Nian H, Shao H, Kaplan H, Sun D. Functional Conversion and Dominance of γδ T Subset in Mouse Experimental Autoimmune Uveitis. J Immunol. 2017;198:1429-1438 pubmed 出版商
Sun T, Yang L, Kaur H, Pestel J, Looso M, Nolte H, et al. A reverse signaling pathway downstream of Sema4A controls cell migration via Scrib. J Cell Biol. 2017;216:199-215 pubmed 出版商
Angela M, Endo Y, Asou H, Yamamoto T, Tumes D, Tokuyama H, et al. Fatty acid metabolic reprogramming via mTOR-mediated inductions of PPAR? directs early activation of T cells. Nat Commun. 2016;7:13683 pubmed 出版商
Suzuki K, Hayano Y, Nakai A, Furuta F, Noda M. Adrenergic control of the adaptive immune response by diurnal lymphocyte recirculation through lymph nodes. J Exp Med. 2016;213:2567-2574 pubmed
Roncagalli R, Cucchetti M, Jarmuzynski N, Gregoire C, Bergot E, Audebert S, et al. The scaffolding function of the RLTPR protein explains its essential role for CD28 co-stimulation in mouse and human T cells. J Exp Med. 2016;213:2437-2457 pubmed
Pageon S, Tabarin T, Yamamoto Y, Ma Y, Nicovich P, Bridgeman J, et al. Functional role of T-cell receptor nanoclusters in signal initiation and antigen discrimination. Proc Natl Acad Sci U S A. 2016;113:E5454-63 pubmed 出版商
Orta Mascaró M, Consuegra Fernández M, Carreras E, Roncagalli R, Carreras Sureda A, Alvarez P, et al. CD6 modulates thymocyte selection and peripheral T cell homeostasis. J Exp Med. 2016;213:1387-97 pubmed 出版商
Collins N, Jiang X, Zaid A, Macleod B, Li J, Park C, et al. Skin CD4(+) memory T cells exhibit combined cluster-mediated retention and equilibration with the circulation. Nat Commun. 2016;7:11514 pubmed 出版商
Redpath S, Van Der Werf N, MacDonald A, Maizels R, Taylor M. Schistosoma mansoni Larvae Do Not Expand or Activate Foxp3+ Regulatory T Cells during Their Migratory Phase. Infect Immun. 2015;83:3881-9 pubmed 出版商
Guy C, Vignali K, Temirov J, Bettini M, Overacre A, Smeltzer M, et al. Distinct TCR signaling pathways drive proliferation and cytokine production in T cells. Nat Immunol. 2013;14:262-70 pubmed 出版商
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Chappaz S, Flueck L, Farr A, Rolink A, Finke D. Increased TSLP availability restores T- and B-cell compartments in adult IL-7 deficient mice. Blood. 2007;110:3862-70 pubmed
Tsukumo S, Hirose K, Maekawa Y, Kishihara K, Yasutomo K. Lunatic fringe controls T cell differentiation through modulating notch signaling. J Immunol. 2006;177:8365-71 pubmed
产品信息
抗原 :
TCR乙链
Apps. Abbrev. :
流式细胞仪, 免疫组化-F
目录 :
109217
克隆 :
H57-597
产品 :
Alexa Fluor® 647 anti-mouse TCR β chain
抗体亚型 :
亚美尼亚仓鼠IgG
其他名称 :
TCR-β链, TCR-β, β-TCR
规格 :
25微克
价格(美元) :
85美元
反应物种 :
小鼠
克隆性 :
单克隆
宿主 :
亚美尼亚仓鼠
共轭标签/标签/标记 :
A647
免疫原 :
亲和纯化TCR来自小鼠DO-11.10细胞
应用注释 :
H57-597 is a hamster mAb directed to an epitope of the C region of TCR β chain 12 . The H57-597 antibody does not cross-react with γ/δ TCR-bearing T cells. Immobilized or soluble H57-597 antibody can activate α/β TCR-bearing T cells. Additional reported applications (for the relevant formats) for this antibody include: immunoprecipitation 2 , in vitro stimulation 2,3 , in vivo depletion 4-6 , and immunohistochemical staining of acetone-fixed frozen sections 7,8,9 . The Ultra-LEAF™ purified antibody (Endotoxin 0.01 EU/μg, Azide-Free, 0.2 μm filtered) is recommended for functional assays (Cat. No. 109253-109258).
更多信息或购买 :
公司信息
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品,旨在加速生命科学领域的研发工作。