产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
Alexa Fluor® 647 anti-mouse Ly-6G
目录 :
127610
规格 :
100微克
价格 :
265美元
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
AF647
克隆名称 :
1A8
反应物种 :
人类, 小鼠
应用 :
免疫组化, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫组化-自由浮动切片, 抑制或激活实验, mass cytometry
更多信息或购买 :
文章摘录数: 148
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 图 s6a
Lee A, Pingali S, Pinilla Ibarz J, Atchison M, Koumenis C, Argon Y, et al. Loss of AID exacerbates the malignant progression of CLL. Leukemia. 2022;36:2430-2442 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s2
Aiken T, Erbe A, Zebertavage L, Komjathy D, Feils A, Rodriguez M, et al. Mechanism of effective combination radio-immunotherapy against 9464D-GD2, an immunologically cold murine neuroblastoma. J Immunother Cancer. 2022;10: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1a
Ngamsri K, Fuhr A, Schindler K, Simelitidis M, Hagen M, Zhang Y, et al. Sevoflurane Dampens Acute Pulmonary Inflammation via the Adenosine Receptor A2B and Heme Oxygenase-1. Cells. 2022;11: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4a, 4c
Seung H, Wröbel J, Wadle C, B xfc hler T, Chiang D, Rettkowski J, et al. P2Y12-dependent activation of hematopoietic stem and progenitor cells promotes emergency hematopoiesis after myocardial infarction. Basic Res Cardiol. 2022;117:16 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:400; 图 5b
Niemi J, DeFrancesco Oranburg T, Cox A, Lindborg J, Echevarria F, McCluskey J, et al. The Conditioning Lesion Response in Dorsal Root Ganglion Neurons Is Inhibited in Oncomodulin Knock-Out Mice. Eneuro. 2022;9: pubmed 出版商
  • 流式细胞仪; 小鼠; 1:150; 图 s2
Mach xe1 x10d ek T, Leontovy x10d R, x160 m xed dov xe1 B, Majer M, Vondr xe1 x10d ek O, Vojt x11b chov xe1 I, et al. Mechanisms of the host immune response and helminth-induced pathology during Trichobilharzia regenti (Schistosomatidae) neuroinvasion in mice. PLoS Pathog. 2022;18:e1010302 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s3a
Vaillant L, Oster P, McMillan B, Orozco Fernandez E, Velin D. GM-CSF is key in the efficacy of vaccine-induced reduction of Helicobacter pylori infection. Helicobacter. 2022;27:e12875 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:1000; 图 7
Chakraborty R, Maltz M, Del Castillo D, Tandel P, Messih N, Anguiano M, et al. Selective Targeting of Tumour Necrosis Factor Receptor 1 Induces Stable Protection from Crohn's-Like Ileitis in TNFΔARE Mice. J Crohns Colitis. 2022;16:978-991 pubmed 出版商
  • 流式细胞仪; 人类; 图 s3a
Fahy N, Palomares Cabeza V, Lolli A, Witte Bouma J, Merino A, Ridwan Y, et al. Chondrogenically Primed Human Mesenchymal Stem Cells Persist and Undergo Early Stages of Endochondral Ossification in an Immunocompetent Xenogeneic Model. Front Immunol. 2021;12:715267 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 6c
Gurley J, Gmyrek G, Hargis E, Bishop G, Carr D, Elliott M. The Chx10-Traf3 Knockout Mouse as a Viable Model to Study Neuronal Immune Regulation. Cells. 2021;10: pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 s2a
Otto N, Pereverzeva L, Léopold V, Ramirez Moral I, Roelofs J, van Heijst J, et al. Hypoxia-Inducible Factor-1α in Macrophages, but Not in Neutrophils, Is Important for Host Defense during Klebsiella pneumoniae-Induced Pneumosepsis. Mediators Inflamm. 2021;2021:9958281 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:500; 图 5b, 5d
Moreira T, Mangani D, Cox L, Leibowitz J, Lobo E, Oliveira M, et al. PD-L1+ and XCR1+ dendritic cells are region-specific regulators of gut homeostasis. Nat Commun. 2021;12:4907 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3
Forman R, Logunova L, Smith H, Wemyss K, Mair I, Boon L, et al. Trichuris muris infection drives cell-intrinsic IL4R alpha independent colonic RELMα+ macrophages. PLoS Pathog. 2021;17:e1009768 pubmed 出版商
  • 流式细胞仪; 小鼠
Mathä L, Romera Hernandez M, Steer C, Yin Y, Orangi M, Shim H, et al. Migration of Lung Resident Group 2 Innate Lymphoid Cells Link Allergic Lung Inflammation and Liver Immunity. Front Immunol. 2021;12:679509 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:200
Van De Velde L, Allen E, Crawford J, Wilson T, Guy C, Russier M, et al. Neuroblastoma Formation Requires Unconventional CD4 T Cells and Arginase-1-Dependent Myeloid Cells. Cancer Res. 2021;81:5047-5059 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2b
Petermann M, Orfanos Z, Sellau J, Gharaibeh M, Lotter H, Fleischer B, et al. CCR2 Deficiency Impairs Ly6Clo and Ly6Chi Monocyte Responses in Orientia tsutsugamushi Infection. Front Immunol. 2021;12:670219 pubmed 出版商
  • 流式细胞仪; 小鼠
Bohannon C, Ende Z, Cao W, Mboko W, Ranjan P, Kumar A, et al. Influenza Virus Infects and Depletes Activated Adaptive Immune Responders. Adv Sci (Weinh). 2021;8:e2100693 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5a
Okunuki Y, Tabor S, Lee M, Connor K. CD47 Deficiency Ameliorates Ocular Autoimmune Inflammation. Front Immunol. 2021;12:680568 pubmed 出版商
  • 流式细胞仪; 小鼠
Geng G, Liu J, Xu C, Pei Y, Chen L, Mu C, et al. Receptor-mediated mitophagy regulates EPO production and protects against renal anemia. elife. 2021;10: pubmed 出版商
  • 流式细胞仪; 小鼠; 1:200; 图 5m
Piñeiro Hermida S, Martinez P, Blasco M. Short and dysfunctional telomeres protect from allergen-induced airway inflammation. Aging Cell. 2021;20:e13352 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1c
Go D, Lee S, Lee S, Woo S, Kim K, Kim K, et al. Programmed Death Ligand 1-Expressing Classical Dendritic Cells MitigateHelicobacter-Induced Gastritis. Cell Mol Gastroenterol Hepatol. 2021;12:715-739 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:500; 图 6a
Borges P, Waclawiak I, Georgii J, Fraga Junior V, Barros J, Lemos F, et al. Adenosine Diphosphate Improves Wound Healing in Diabetic Mice Through P2Y12 Receptor Activation. Front Immunol. 2021;12:651740 pubmed 出版商
  • 流式细胞仪; 人类; 1:250; 图 s9
Qin W, Brands X, Van T Veer C, F de Vos A, Sirard J, J T H Roelofs J, et al. Bronchial epithelial DNA methyltransferase 3b dampens pulmonary immune responses during Pseudomonas aeruginosa infection. PLoS Pathog. 2021;17:e1009491 pubmed 出版商
  • 流式细胞仪; 小鼠
Ngamsri K, Gamper Tsigaras J, Reutershan J, Konrad F. Fractalkine Is Linked to the Necrosome Pathway in Acute Pulmonary Inflammation. Front Med (Lausanne). 2021;8:591790 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5b
Petty A, Dai R, Lapalombella R, Baiocchi R, Benson D, Li Z, et al. Hedgehog-induced PD-L1 on tumor-associated macrophages is critical for suppression of tumor-infiltrating CD8+ T cell function. JCI Insight. 2021;6: pubmed 出版商
  • 免疫组化; 小鼠; 1:1000; 图 2
Steenbrugge J, Vander Elst N, Demeyere K, De Wever O, Sanders N, van den Broeck W, et al. OMO-1 reduces progression and enhances cisplatin efficacy in a 4T1-based non-c-MET addicted intraductal mouse model for triple-negative breast cancer. NPJ Breast Cancer. 2021;7:27 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:500; 图 s1b, s1c, s1d
  • 免疫组化; 小鼠; 1:500; 图 4d
Thanabalasuriar A, Chiang A, Morehouse C, Camara M, Hawkins S, Keller A, et al. PD-L1+ neutrophils contribute to injury-induced infection susceptibility. Sci Adv. 2021;7: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s1c, s4d
Can xe8 S, Van Snick J, Uyttenhove C, Pilotte L, van den Eynde B. TGFβ1 neutralization displays therapeutic efficacy through both an immunomodulatory and a non-immune tumor-intrinsic mechanism. J Immunother Cancer. 2021;9: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s1a
Brownlie D, Doughty Shenton D, Yh Soong D, Nixon C, O Carragher N, M Carlin L, et al. Metastasis-associated macrophages constrain antitumor capability of natural killer cells in the metastatic site at least partially by membrane bound transforming growth factor β. J Immunother Cancer. 2021;9: pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 4c
Wang X, Liu D, Qin W, Liu Y, Yuan X, Zhang X, et al. P2RX1-Involved Glycolytic Metabolism Supports Neutrophil Activation in Acute Pancreatitis. Front Immunol. 2020;11:549179 pubmed 出版商
  • 流式细胞仪; 小鼠
Yoon S, Song S, Shin J, Kang S, Kim H, You H. Protective Effects of Korean Herbal Remedy against Airway Inflammation in an Allergic Asthma by Suppressing Eosinophil Recruitment and Infiltration in Lung. Antioxidants (Basel). 2020;10: pubmed 出版商
  • 流式细胞仪; 小鼠; 1:250; 图 s8a
Torretta S, Scagliola A, Ricci L, Mainini F, Di Marco S, Cuccovillo I, et al. D-mannose suppresses macrophage IL-1β production. Nat Commun. 2020;11:6343 pubmed 出版商
  • 免疫组化; 小鼠; 1:250
Jinno A, Hayashida A, Jenkinson H, Park P. Syndecan-1 Promotes Streptococcus pneumoniae Corneal Infection by Facilitating the Assembly of Adhesive Fibronectin Fibrils. MBio. 2020;11: pubmed 出版商
  • 流式细胞仪; 小鼠
Myers D, Abram C, Wildes D, Belwafa A, Welsh A, Schulze C, et al. Shp1 Loss Enhances Macrophage Effector Function and Promotes Anti-Tumor Immunity. Front Immunol. 2020;11:576310 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 6
Gurley J, Gmyrek G, McClellan M, Hargis E, Hauck S, Dozmorov M, et al. Neuroretinal-Derived Caveolin-1 Promotes Endotoxin-Induced Inflammation in the Murine Retina. Invest Ophthalmol Vis Sci. 2020;61:19 pubmed 出版商
  • 流式细胞仪; 小鼠
Lissner M, Cumnock K, Davis N, Vilches Moure J, Basak P, Navarrete D, et al. Metabolic profiling during malaria reveals the role of the aryl hydrocarbon receptor in regulating kidney injury. elife. 2020;9: pubmed 出版商
  • 流式细胞仪; 小鼠
Shi H, Lo T, Ma D, Condor B, Lesmana B, Parungao R, et al. Dihydrotestosterone (DHT) Enhances Wound Healing of Major Burn Injury by Accelerating Resolution of Inflammation in Mice. Int J Mol Sci. 2020;21: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1f
Li N, Kang Y, Wang L, Huff S, Tang R, Hui H, et al. ALKBH5 regulates anti-PD-1 therapy response by modulating lactate and suppressive immune cell accumulation in tumor microenvironment. Proc Natl Acad Sci U S A. 2020;117:20159-20170 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:200; 图 s3
Azcutia V, Kelm M, Luissint A, Boerner K, Flemming S, Quirós M, et al. Neutrophil expressed CD47 regulates CD11b/CD18-dependent neutrophil transepithelial migration in the intestine in vivo. Mucosal Immunol. 2020;: pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 1:250; 图 3s1b
  • 流式细胞仪; 小鼠; 1:800; 图 2d, 3s3c
Burfeind K, Zhu X, Norgard M, Levasseur P, Huisman C, Buenafe A, et al. Circulating myeloid cells invade the central nervous system to mediate cachexia during pancreatic cancer. elife. 2020;9: pubmed 出版商
  • 流式细胞仪; 小鼠
Ngamsri K, Jans C, Putri R, Schindler K, Gamper Tsigaras J, Eggstein C, et al. Inhibition of CXCR4 and CXCR7 Is Protective in Acute Peritoneal Inflammation. Front Immunol. 2020;11:407 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:400; 图 1a, 1d
Wuggenig P, Kaya B, Melhem H, Ayata C, Hruz P, Sayan A, et al. Loss of the branched-chain amino acid transporter CD98hc alters the development of colonic macrophages in mice. Commun Biol. 2020;3:130 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2
Watanabe M, Kaneko Y, Ohishi Y, Kinoshita M, Sakairi T, Ikeuchi H, et al. Importance of methodology in the evaluation of renal mononuclear phagocytes and analysis of a model of experimental nephritis with Shp1 conditional knockout mice. Biochem Biophys Rep. 2020;22:100741 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s1
Luker A, Graham L, Smith T, Camarena C, Zellner M, Gilmer J, et al. The DNA methyltransferase inhibitor, guadecitabine, targets tumor-induced myelopoiesis and recovers T cell activity to slow tumor growth in combination with adoptive immunotherapy in a mouse model of breast cancer. BMC Immunol. 2020;21:8 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s4, 2
Sun D, Zhang M, Sun P, Liu G, Strickland A, Chen Y, et al. VCAM1/VLA4 interaction mediates Ly6Clow monocyte recruitment to the brain in a TNFR signaling dependent manner during fungal infection. PLoS Pathog. 2020;16:e1008361 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2a
Clark D, Brazina S, Yang F, Hu D, Hsieh C, Niemi E, et al. Age-related changes to macrophages are detrimental to fracture healing in mice. Aging Cell. 2020;19:e13112 pubmed 出版商
  • 流式细胞仪; 小鼠; 2 ug/ml; 图 s3a
Wang J, Li P, Yu Y, Fu Y, Jiang H, Lu M, et al. Pulmonary surfactant-biomimetic nanoparticles potentiate heterosubtypic influenza immunity. Science. 2020;367: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s1a
Wilson Z, Witt H, Hazlett L, Harman M, Neumann B, Whitman A, et al. Context-Dependent Role of Vinculin in Neutrophil Adhesion, Motility and Trafficking. Sci Rep. 2020;10:2142 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1c
Khorooshi R, Marczynska J, Dieu R, Wais V, Hansen C, Kavan S, et al. Innate signaling within the central nervous system recruits protective neutrophils. Acta Neuropathol Commun. 2020;8:2 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s4
Eastman A, Xu J, Bermik J, Potchen N, den Dekker A, Neal L, et al. Epigenetic stabilization of DC and DC precursor classical activation by TNFα contributes to protective T cell polarization. Sci Adv. 2019;5:eaaw9051 pubmed 出版商
  • mass cytometry; 小鼠; 1.5 ug/ml; 图 5d
Guo C, Allen B, Hiam K, Dodd D, Van Treuren W, Higginbottom S, et al. Depletion of microbiome-derived molecules in the host using Clostridium genetics. Science. 2019;366: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 e10a
Alspach E, Lussier D, Miceli A, Kizhvatov I, DuPage M, Luoma A, et al. MHC-II neoantigens shape tumour immunity and response to immunotherapy. Nature. 2019;574:696-701 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 e6a
Solis A, Bielecki P, Steach H, Sharma L, Harman C, Yun S, et al. Mechanosensation of cyclical force by PIEZO1 is essential for innate immunity. Nature. 2019;573:69-74 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:200; 图 2i
Culemann S, Grüneboom A, Nicolás Ávila J, Weidner D, Lämmle K, Rothe T, et al. Locally renewing resident synovial macrophages provide a protective barrier for the joint. Nature. 2019;572:670-675 pubmed 出版商
  • 流式细胞仪; 小鼠
Di Pilato M, Kim E, Cadilha B, Prüßmann J, Nasrallah M, Seruggia D, et al. Targeting the CBM complex causes Treg cells to prime tumours for immune checkpoint therapy. Nature. 2019;570:112-116 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 1a
Cunin P, Bouslama R, Machlus K, Martínez Bonet M, Lee P, Wactor A, et al. Megakaryocyte emperipolesis mediates membrane transfer from intracytoplasmic neutrophils to platelets. elife. 2019;8: pubmed 出版商
  • 流式细胞仪; 小鼠; 1:200; 图 4b
Kuriakose J, Redecke V, Guy C, Zhou J, Wu R, Ippagunta S, et al. Patrolling monocytes promote the pathogenesis of early lupus-like glomerulonephritis. J Clin Invest. 2019;129:2251-2265 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1.25 ug/ml; 图 3b
Lemarchand E, Barrington J, Chenery A, Haley M, Coutts G, Allen J, et al. Extent of Ischemic Brain Injury After Thrombotic Stroke Is Independent of the NLRP3 (NACHT, LRR and PYD Domains-Containing Protein 3) Inflammasome. Stroke. 2019;50:1232-1239 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100; 图 e8a
Jacome Galarza C, Percin G, Muller J, Mass E, Lazarov T, Eitler J, et al. Developmental origin, functional maintenance and genetic rescue of osteoclasts. Nature. 2019;568:541-545 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3a
Paudel S, Baral P, Ghimire L, Bergeron S, Jin L, De Corte J, et al. CXCL1 regulates neutrophil homeostasis in pneumonia-derived sepsis caused by Streptococcus pneumoniae serotype 3. Blood. 2019;: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1a
Düsedau H, Kleveman J, Figueiredo C, Biswas A, Steffen J, Kliche S, et al. p75NTR regulates brain mononuclear cell function and neuronal structure in Toxoplasma infection-induced neuroinflammation. Glia. 2019;67:193-211 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s20b
Normand S, Waldschmitt N, Neerincx A, Martinez Torres R, Chauvin C, Couturier Maillard A, et al. Proteasomal degradation of NOD2 by NLRP12 in monocytes promotes bacterial tolerance and colonization by enteropathogens. Nat Commun. 2018;9:5338 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s1
Kaplanov I, Carmi Y, Kornetsky R, Shemesh A, Shurin G, Shurin M, et al. Blocking IL-1β reverses the immunosuppression in mouse breast cancer and synergizes with anti-PD-1 for tumor abrogation. Proc Natl Acad Sci U S A. 2019;116:1361-1369 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100; 图 4a
Benmerzoug S, Rose S, Bounab B, Gosset D, Duneau L, Chenuet P, et al. STING-dependent sensing of self-DNA drives silica-induced lung inflammation. Nat Commun. 2018;9:5226 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s8a
Sato Y, Bolzenius J, Eteleeb A, Su X, Maher C, Sehn J, et al. CD4+ T cells induce rejection of urothelial tumors after immune checkpoint blockade. JCI Insight. 2018;3: pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100; 图 3e, 3h
Mouhadeb O, Ben Shlomo S, Cohen K, Farkash I, Gruber S, Maharshak N, et al. Impaired COMMD10-Mediated Regulation of Ly6Chi Monocyte-Driven Inflammation Disrupts Gut Barrier Function. Front Immunol. 2018;9:2623 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3d
Klement J, Paschall A, Redd P, Ibrahim M, Lu C, Yang D, et al. An osteopontin/CD44 immune checkpoint controls CD8+ T cell activation and tumor immune evasion. J Clin Invest. 2018;128:5549-5560 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s2a
Meyer I, Goetzke C, Kespohl M, Sauter M, Heuser A, Eckstein V, et al. Silencing the CSF-1 Axis Using Nanoparticle Encapsulated siRNA Mitigates Viral and Autoimmune Myocarditis. Front Immunol. 2018;9:2303 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2a
Arnold I, Artola Borán M, Tallón de Lara P, Kyburz A, Taube C, OTTEMANN K, et al. Eosinophils suppress Th1 responses and restrict bacterially induced gastrointestinal inflammation. J Exp Med. 2018;215:2055-2072 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5b
Quenum Zangbede F, Chauhan A, Sharma J, Mishra B. Galectin-3 in M2 Macrophages Plays a Protective Role in Resolution of Neuropathology in Brain Parasitic Infection by Regulating Neutrophil Turnover. J Neurosci. 2018;38:6737-6750 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s3b
Napolitano A, van der Veen A, Bunyan M, Borg A, Frith D, Howell S, et al. Cysteine-Reactive Free ISG15 Generates IL-1β-Producing CD8α+ Dendritic Cells at the Site of Infection. J Immunol. 2018;201:604-614 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2c
Lau A, Chung H, Komada T, Platnich J, Sandall C, Choudhury S, et al. Renal immune surveillance and dipeptidase-1 contribute to contrast-induced acute kidney injury. J Clin Invest. 2018;128:2894-2913 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:1000; 图 s3e
Tsiantoulas D, Sage A, Göderle L, Ozsvar Kozma M, Murphy D, Porsch F, et al. BAFF Neutralization Aggravates Atherosclerosis. Circulation. 2018;: pubmed 出版商
  • 流式细胞仪; 小鼠; 1:200; 图 s2a
Huynh J, Lin C, Kimmey J, Jarjour N, Schwarzkopf E, Bradstreet T, et al. Bhlhe40 is an essential repressor of IL-10 during Mycobacterium tuberculosis infection. J Exp Med. 2018;215:1823-1838 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1s1a
Thompson T, Jackson B, Li P, Wang J, Kim A, Huang K, et al. Tumor-derived CSF-1 induces the NKG2D ligand RAE-1δ on tumor-infiltrating macrophages. elife. 2018;7: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1b
Crosby E, Wei J, Yang X, Lei G, Wang T, Liu C, et al. Complimentary mechanisms of dual checkpoint blockade expand unique T-cell repertoires and activate adaptive anti-tumor immunity in triple-negative breast tumors. Oncoimmunology. 2018;7:e1421891 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:200; 图 s1a
Chen W, Yang J, Wu Y, Li L, Li R, Chang Y, et al. IL-33/ST2 axis mediates hyperplasia of intrarenal urothelium in obstructive renal injury. Exp Mol Med. 2018;50:36 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s2c
Kobayashi Y, Inagawa H, Kohchi C, Kazumura K, Tsuchiya H, Miwa T, et al. Oral administration of Pantoea agglomerans-derived lipopolysaccharide prevents development of atherosclerosis in high-fat diet-fed apoE-deficient mice via ameliorating hyperlipidemia, pro-inflammatory mediators and oxidative responses. PLoS ONE. 2018;13:e0195008 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:200; 图 1b
Tsubaki T, Kadonosono T, Sakurai S, Shiozawa T, Goto T, Sakai S, et al. Novel adherent CD11b+ Gr-1+ tumor-infiltrating cells initiate an immunosuppressive tumor microenvironment. Oncotarget. 2018;9:11209-11226 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1a
Panduro M, Benoist C, Mathis D. Treg cells limit IFN-? production to control macrophage accrual and phenotype during skeletal muscle regeneration. Proc Natl Acad Sci U S A. 2018;115:E2585-E2593 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3a
Pitts M, Combs T, D Orazio S. Neutrophils from Both Susceptible and Resistant Mice Efficiently Kill Opsonized Listeria monocytogenes. Infect Immun. 2018;86: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1c
  • 免疫组化; 小鼠
Bogoslowski A, Butcher E, Kubes P. Neutrophils recruited through high endothelial venules of the lymph nodes via PNAd intercept disseminating Staphylococcus aureus. Proc Natl Acad Sci U S A. 2018;115:2449-2454 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:20; 图 3c
Yoshida S, Hagiwara Y, Tsuchiya M, Shinoda M, Koide M, Hatakeyama H, et al. Involvement of neutrophils and interleukin-18 in nociception in a mouse model of muscle pain. Mol Pain. 2018;14:1744806918757286 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:200; 图 5h, 5i
Campana L, Starkey Lewis P, Pellicoro A, Aucott R, Man J, O Duibhir E, et al. The STAT3-IL-10-IL-6 Pathway Is a Novel Regulator of Macrophage Efferocytosis and Phenotypic Conversion in Sterile Liver Injury. J Immunol. 2018;200:1169-1187 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 3a
Zhang Y, Khairallah C, Sheridan B, van der Velden A, Bliska J. CCR2+ Inflammatory Monocytes Are Recruited to Yersinia pseudotuberculosis Pyogranulomas and Dictate Adaptive Responses at the Expense of Innate Immunity during Oral Infection. Infect Immun. 2018;86: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4a
Akiel M, Guo C, Li X, Rajasekaran D, Mendoza R, Robertson C, et al. IGFBP7 Deletion Promotes Hepatocellular Carcinoma. Cancer Res. 2017;77:4014-4025 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5a
Kwan B, Zhu E, Tzeng A, Sugito H, Eltahir A, Ma B, et al. Integrin-targeted cancer immunotherapy elicits protective adaptive immune responses. J Exp Med. 2017;214:1679-1690 pubmed 出版商
  • 免疫组化; 小鼠; 2.5 ug/ml; 图 5f
Kretschmer S, Pieper M, Hüttmann G, Bölke T, Wollenberg B, Marsh L, et al. Autofluorescence multiphoton microscopy for visualization of tissue morphology and cellular dynamics in murine and human airways. Lab Invest. 2016;96:918-31 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2b
Lo T, Silveira P, Fromm P, Verma N, Vu P, Kupresanin F, et al. Characterization of the Expression and Function of the C-Type Lectin Receptor CD302 in Mice and Humans Reveals a Role in Dendritic Cell Migration. J Immunol. 2016;197:885-98 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 图 6b
Quirino G, Nascimento M, Davoli Ferreira M, Sacramento L, Lima M, Almeida R, et al. Interleukin-27 (IL-27) Mediates Susceptibility to Visceral Leishmaniasis by Suppressing the IL-17-Neutrophil Response. Infect Immun. 2016;84:2289-2298 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 4i
Spiegel A, Brooks M, Houshyar S, Reinhardt F, Ardolino M, Fessler E, et al. Neutrophils Suppress Intraluminal NK Cell-Mediated Tumor Cell Clearance and Enhance Extravasation of Disseminated Carcinoma Cells. Cancer Discov. 2016;6:630-49 pubmed 出版商
Adrover J, Carrau L, Daßler Plenker J, Bram Y, Chandar V, Houghton S, et al. Disulfiram inhibits neutrophil extracellular trap formation and protects rodents from acute lung injury and SARS-CoV-2 infection. JCI Insight. 2022;7: pubmed 出版商
Li H, Zhang Y, Liu M, Fan C, Feng C, Lu Q, et al. Targeting PDE4 as a promising therapeutic strategy in chronic ulcerative colitis through modulating mucosal homeostasis. Acta Pharm Sin B. 2022;12:228-245 pubmed 出版商
Pizzurro G, Liu C, Bridges K, Alexander A, Huang A, Baskaran J, et al. 3D Model of the Early Melanoma Microenvironment Captures Macrophage Transition into a Tumor-Promoting Phenotype. Cancers (Basel). 2021;13: pubmed 出版商
Jiao H, Jiang D, Du W, Ji L, Yang Y, Li X, et al. Mitocytosis, a migrasome-mediated mitochondrial quality-control process. Cell. 2021;184:2896-2910.e13 pubmed 出版商
Barkaway A, Rolas L, Joulia R, Bodkin J, Lenn T, Owen Woods C, et al. Age-related changes in the local milieu of inflamed tissues cause aberrant neutrophil trafficking and subsequent remote organ damage. Immunity. 2021;54:1494-1510.e7 pubmed 出版商
Friščić J, Böttcher M, Reinwald C, Bruns H, Wirth B, Popp S, et al. The complement system drives local inflammatory tissue priming by metabolic reprogramming of synovial fibroblasts. Immunity. 2021;54:1002-1021.e10 pubmed 出版商
Tummala G, CRAIN A, Rowlan J, Pepple K. Characterization of Gene Therapy Associated Uveitis Following Intravitreal Adeno-Associated Virus Injection in Mice. Invest Ophthalmol Vis Sci. 2021;62:41 pubmed 出版商
Ringel A, Drijvers J, Baker G, Catozzi A, García Cañaveras J, Gassaway B, et al. Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity. Cell. 2020;183:1848-1866.e26 pubmed 出版商
Joseph A, Chu C, Feng G, Dholakia K, Schallek J. Label-free imaging of immune cell dynamics in the living retina using adaptive optics. elife. 2020;9: pubmed 出版商
Lin R, Zhang Y, Pradhan K, Li L. TICAM2-related pathway mediates neutrophil exhaustion. Sci Rep. 2020;10:14397 pubmed 出版商
John S, Rolnick K, Wilson L, Wong S, Van Gelder R, Pepple K. Bioluminescence for in vivo detection of cell-type-specific inflammation in a mouse model of uveitis. Sci Rep. 2020;10:11377 pubmed 出版商
Tsourouktsoglou T, Warnatsch A, Ioannou M, Hoving D, Wang Q, Papayannopoulos V. Histones, DNA, and Citrullination Promote Neutrophil Extracellular Trap Inflammation by Regulating the Localization and Activation of TLR4. Cell Rep. 2020;31:107602 pubmed 出版商
Shin J, Kwon M, Hwang J, Lee S, Lee J, Kim H, et al. Keratinocyte transglutaminase 2 promotes CCR6+ γδT-cell recruitment by upregulating CCL20 in psoriatic inflammation. Cell Death Dis. 2020;11:301 pubmed 出版商
Madenspacher J, Morrell E, Gowdy K, McDonald J, Thompson B, Muse G, et al. Cholesterol 25-hydroxylase promotes efferocytosis and resolution of lung inflammation. JCI Insight. 2020;5: pubmed 出版商
Jackson Jones L, Smith P, Portman J, Magalhaes M, Mylonas K, Vermeren M, et al. Stromal Cells Covering Omental Fat-Associated Lymphoid Clusters Trigger Formation of Neutrophil Aggregates to Capture Peritoneal Contaminants. Immunity. 2020;52:700-715.e6 pubmed 出版商
Shahid M, Cavalcante P, Knight C, Barkema H, Han B, Gao J, et al. Murine and Human Cathelicidins Contribute Differently to Hallmarks of Mastitis Induced by Pathogenic Prototheca bovis Algae. Front Cell Infect Microbiol. 2020;10:31 pubmed 出版商
Ueki H, Wang I, Zhao D, Gunzer M, Kawaoka Y. Multicolor two-photon imaging of in vivo cellular pathophysiology upon influenza virus infection using the two-photon IMPRESS. Nat Protoc. 2020;15:1041-1065 pubmed 出版商
Wu N, Cernysiov V, Davidson D, Song H, Tang J, Luo S, et al. Critical Role of Lipid Scramblase TMEM16F in Phosphatidylserine Exposure and Repair of Plasma Membrane after Pore Formation. Cell Rep. 2020;30:1129-1140.e5 pubmed 出版商
Shahid M, Cobo E, Chen L, Cavalcante P, Barkema H, Gao J, et al. Prototheca zopfii genotype II induces mitochondrial apoptosis in models of bovine mastitis. Sci Rep. 2020;10:698 pubmed 出版商
Ge C, Monk I, Pizzolla A, Wang N, Bedford J, Stinear T, et al. Bystander Activation of Pulmonary Trm Cells Attenuates the Severity of Bacterial Pneumonia by Enhancing Neutrophil Recruitment. Cell Rep. 2019;29:4236-4244.e3 pubmed 出版商
Li S, Lu X, Shao Q, Chen Z, Huang Q, Jiao Z, et al. Early Histone Deacetylase Inhibition Mitigates Ischemia/Reperfusion Brain Injury by Reducing Microglia Activation and Modulating Their Phenotype. Front Neurol. 2019;10:893 pubmed 出版商
Merz S, Korste S, Bornemann L, Michel L, Stock P, Squire A, et al. Contemporaneous 3D characterization of acute and chronic myocardial I/R injury and response. Nat Commun. 2019;10:2312 pubmed 出版商
Chojnacki A, Wójcik K, Petri B, Aulakh G, Jacobsen E, Lesuer W, et al. Intravital imaging allows real-time characterization of tissue resident eosinophils. Commun Biol. 2019;2:181 pubmed 出版商
Gall M, Zhang H, Lee Q, Jolly C, McCaughan G, Cook A, et al. Immune regeneration in irradiated mice is not impaired by the absence of DPP9 enzymatic activity. Sci Rep. 2019;9:7292 pubmed 出版商
Komuczki J, Tuzlak S, Friebel E, Hartwig T, Spath S, Rosenstiel P, et al. Fate-Mapping of GM-CSF Expression Identifies a Discrete Subset of Inflammation-Driving T Helper Cells Regulated by Cytokines IL-23 and IL-1β. Immunity. 2019;: pubmed 出版商
Thanabalasuriar A, Scott B, Peiseler M, Willson M, Zeng Z, Warrener P, et al. Neutrophil Extracellular Traps Confine Pseudomonas aeruginosa Ocular Biofilms and Restrict Brain Invasion. Cell Host Microbe. 2019;25:526-536.e4 pubmed 出版商
Li H, Fan C, Feng C, Wu Y, Lu H, He P, et al. Inhibition of phosphodiesterase-4 attenuates murine ulcerative colitis through interference with mucosal immunity. Br J Pharmacol. 2019;176:2209-2226 pubmed 出版商
Geng S, Zhang Y, Lee C, Li L. Novel reprogramming of neutrophils modulates inflammation resolution during atherosclerosis. Sci Adv. 2019;5:eaav2309 pubmed 出版商
Girbl T, Lenn T, Pérez L, Rolas L, Barkaway A, Thiriot A, et al. Distinct Compartmentalization of the Chemokines CXCL1 and CXCL2 and the Atypical Receptor ACKR1 Determine Discrete Stages of Neutrophil Diapedesis. Immunity. 2018;49:1062-1076.e6 pubmed 出版商
Miyatake Y, Yamano T, Hanayama R. Myoferlin-Mediated Lysosomal Exocytosis Regulates Cytotoxicity by Phagocytes. J Immunol. 2018;201:3051-3057 pubmed 出版商
Li S, Herrera G, Tam K, Lizarraga J, Beedle M, Winuthayanon W. Estrogen Action in the Epithelial Cells of the Mouse Vagina Regulates Neutrophil Infiltration and Vaginal Tissue Integrity. Sci Rep. 2018;8:11247 pubmed 出版商
Chung L, Thiele Orberg E, Geis A, Chan J, Fu K, Destefano Shields C, et al. Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells. Cell Host Microbe. 2018;23:203-214.e5 pubmed 出版商
Chang T, Huang J, Lin H, Chen W, Lee Y, Hsu L, et al. Dectin-2 is a primary receptor for NLRP3 inflammasome activation in dendritic cell response to Histoplasma capsulatum. PLoS Pathog. 2017;13:e1006485 pubmed 出版商
Furuhashi K, Chua Y, Wong K, Zhou Q, Lee D, Liong K, et al. Priming with high and low respiratory allergen dose induces differential CD4+ T helper type 2 cells and IgE/IgG1 antibody responses in mice. Immunology. 2017;151:227-238 pubmed 出版商
Hor J, Heath W, Mueller S. Neutrophils are dispensable in the modulation of T cell immunity against cutaneous HSV-1 infection. Sci Rep. 2017;7:41091 pubmed 出版商
Geng S, Chen K, Yuan R, Peng L, Maitra U, Diao N, et al. The persistence of low-grade inflammatory monocytes contributes to aggravated atherosclerosis. Nat Commun. 2016;7:13436 pubmed 出版商
Kim K, Li J, Barazia A, Tseng A, Youn S, Abbadessa G, et al. ARQ 092, an orally-available, selective AKT inhibitor, attenuates neutrophil-platelet interactions in sickle cell disease. Haematologica. 2017;102:246-259 pubmed 出版商
Rossnagl S, Altrock E, Sens C, Kraft S, Rau K, Milsom M, et al. EDA-Fibronectin Originating from Osteoblasts Inhibits the Immune Response against Cancer. PLoS Biol. 2016;14:e1002562 pubmed 出版商
Bossaller L, Christ A, Pelka K, Nündel K, Chiang P, Pang C, et al. TLR9 Deficiency Leads to Accelerated Renal Disease and Myeloid Lineage Abnormalities in Pristane-Induced Murine Lupus. J Immunol. 2016;197:1044-53 pubmed 出版商
Thiele Orberg E, Fan H, Tam A, Dejea C, Destefano Shields C, Wu S, et al. The myeloid immune signature of enterotoxigenic Bacteroides fragilis-induced murine colon tumorigenesis. Mucosal Immunol. 2017;10:421-433 pubmed 出版商
Katkar G, Sundaram M, NaveenKumar S, Swethakumar B, Sharma R, Paul M, et al. NETosis and lack of DNase activity are key factors in Echis carinatus venom-induced tissue destruction. Nat Commun. 2016;7:11361 pubmed 出版商
Velázquez F, Grodecki Pena A, Knapp A, Salvador A, NEVERS T, Croce K, et al. CD43 Functions as an E-Selectin Ligand for Th17 Cells In Vitro and Is Required for Rolling on the Vascular Endothelium and Th17 Cell Recruitment during Inflammation In Vivo. J Immunol. 2016;196:1305-1316 pubmed 出版商
Kolawole A, Gonzalez Hernandez M, Turula H, Yu C, Elftman M, Wobus C. Oral Norovirus Infection Is Blocked in Mice Lacking Peyer's Patches and Mature M Cells. J Virol. 2016;90:1499-506 pubmed 出版商
Meunier I, Morisseau O, Garneau E, Marois I, Cloutier A, Richter M. Infection with a Mouse-Adapted Strain of the 2009 Pandemic Virus Causes a Highly Severe Disease Associated with an Impaired T Cell Response. PLoS ONE. 2015;10:e0138055 pubmed 出版商
Jhunjhunwala S, Aresta DaSilva S, Tang K, Alvarez D, Webber M, Tang B, et al. Neutrophil Responses to Sterile Implant Materials. PLoS ONE. 2015;10:e0137550 pubmed 出版商
Traboulsi H, Cloutier A, Boyapelly K, Bonin M, Marsault Ã, Cantin A, et al. The Flavonoid Isoliquiritigenin Reduces Lung Inflammation and Mouse Morbidity during Influenza Virus Infection. Antimicrob Agents Chemother. 2015;59:6317-27 pubmed 出版商
Martinod K, Fuchs T, Zitomersky N, Wong S, Demers M, Gallant M, et al. PAD4-deficiency does not affect bacteremia in polymicrobial sepsis and ameliorates endotoxemic shock. Blood. 2015;125:1948-56 pubmed 出版商
Her Z, Teng T, Tan J, Teo T, Kam Y, Lum F, et al. Loss of TLR3 aggravates CHIKV replication and pathology due to an altered virus-specific neutralizing antibody response. EMBO Mol Med. 2015;7:24-41 pubmed 出版商
McCartney Francis N, Jin W, Belkaid Y, McGrady G, Wahl S. Aberrant host defense against Leishmania major in the absence of SLPI. J Leukoc Biol. 2014;96:917-29 pubmed 出版商
Li J, Liu G, Feng W, Zhou Y, Liu M, Wiley J, et al. Neutrophils select hypervirulent CovRS mutants of M1T1 group A Streptococcus during subcutaneous infection of mice. Infect Immun. 2014;82:1579-90 pubmed 出版商
Ng L, Qin J, Roediger B, Wang Y, Jain R, Cavanagh L, et al. Visualizing the neutrophil response to sterile tissue injury in mouse dermis reveals a three-phase cascade of events. J Invest Dermatol. 2011;131:2058-68 pubmed 出版商
Prates D, Araújo Santos T, Luz N, Andrade B, França Costa J, Afonso L, et al. Lutzomyia longipalpis saliva drives apoptosis and enhances parasite burden in neutrophils. J Leukoc Biol. 2011;90:575-82 pubmed 出版商
Fujita M, Kohanbash G, Fellows Mayle W, Hamilton R, Komohara Y, Decker S, et al. COX-2 blockade suppresses gliomagenesis by inhibiting myeloid-derived suppressor cells. Cancer Res. 2011;71:2664-74 pubmed 出版商
Guiducci C, Tripodo C, Gong M, Sangaletti S, Colombo M, Coffman R, et al. Autoimmune skin inflammation is dependent on plasmacytoid dendritic cell activation by nucleic acids via TLR7 and TLR9. J Exp Med. 2010;207:2931-42 pubmed 出版商
Sumagin R, Prizant H, Lomakina E, Waugh R, Sarelius I. LFA-1 and Mac-1 define characteristically different intralumenal crawling and emigration patterns for monocytes and neutrophils in situ. J Immunol. 2010;185:7057-66 pubmed 出版商
Tadagavadi R, REEVES W. Endogenous IL-10 attenuates cisplatin nephrotoxicity: role of dendritic cells. J Immunol. 2010;185:4904-11 pubmed 出版商
Daley J, Thomay A, Connolly M, Reichner J, Albina J. Use of Ly6G-specific monoclonal antibody to deplete neutrophils in mice. J Leukoc Biol. 2008;83:64-70 pubmed
产品信息
抗原 :
Ly-6G
Apps. Abbrev. :
流式细胞仪, 免疫组化-F
目录 :
127610
克隆 :
1A8
产品 :
Alexa Fluor® 647 anti-mouse Ly-6G
抗体亚型 :
Rat IgG2a, κ
其他名称 :
Lymphocyte antigen 6 complex, locus G
规格 :
100微克
价格(美元) :
265美元
反应物种 :
小鼠
克隆性 :
单克隆
宿主 :
大鼠
共轭标签/标签/标记 :
A647
免疫原 :
Ly-6G transfected EL-4J cell line.
应用注释 :
While 1A8 recognizes only Ly-6G, clone RB6-8C5 recognizes both Ly-6G and Ly-6C. Clone RB6-8C5 binds with high affinity to mouse Ly-6G molecules and to a lower extent to Ly-6C 15 . Clone RB6-8C5 impairs the binding of anti-mouse Ly-6G clone 1A8 15 . However, clone RB6-8C5 is able to stain in the presence of anti-mouse Ly-6C clone HK1.4 16 . Additional reported applications (for the relevant formats) include: immunohistochemistry 9 of frozen sections 10 and paraffin-embedded sections 11 , depletion 4, 12-14 , and spatial biology (IBEX) 20,21 . The Ultra-LEAF purified antibody (Endotoxin 0.01 EU/ug, Azide-Free, 0.2 um filtered) is recommended for in vivo studies or highly sensitive assays (Cat. No. 127632, 127649, 127650, 127661 and 127662).
更多信息或购买 :
公司信息
BioLegend
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San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品,旨在加速生命科学领域的研发工作。