产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
亮紫色650™抗人类CD11c
目录 :
301637
规格 :
25试验
价格 :
220美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
BV650
克隆名称 :
3.9
反应物种 :
人类
应用 :
流式细胞仪
更多信息或购买 :
BioLegend 产品网页
文章摘录数: 17
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 人类; 图 1c
Kelly A, Günaltay S, McEntee C, Shuttleworth E, Smedley C, Houston S, et al. Human monocytes and macrophages regulate immune tolerance via integrin αvβ8-mediated TGFβ activation. J Exp Med. 2018;215:2725-2736 pubmed 出版商
  • 流式细胞仪; 人类
Bendall S, Simonds E, Qiu P, Amir E, Krutzik P, Finck R, et al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science. 2011;332:687-96 pubmed 出版商
de Mingo Pulido Á, Hänggi K, Celias D, Gardner A, Li J, Batista Bittencourt B, et al. The inhibitory receptor TIM-3 limits activation of the cGAS-STING pathway in intra-tumoral dendritic cells by suppressing extracellular DNA uptake. Immunity. 2021;54:1154-1167.e7 pubmed 出版商
Camiolo M, Zhou X, Oriss T, Yan Q, Gorry M, Horne W, et al. High-dimensional profiling clusters asthma severity by lymphoid and non-lymphoid status. Cell Rep. 2021;35:108974 pubmed 出版商
Routhu N, Cheedarla N, Gangadhara S, Bollimpelli V, Boddapati A, Shiferaw A, et al. A modified vaccinia Ankara vector-based vaccine protects macaques from SARS-CoV-2 infection, immune pathology, and dysfunction in the lungs. Immunity. 2021;54:542-556.e9 pubmed 出版商
Laing A, Lorenc A, Del Molino Del Barrio I, Das A, Fish M, Monin L, et al. A dynamic COVID-19 immune signature includes associations with poor prognosis. Nat Med. 2020;26:1623-1635 pubmed 出版商
Abd Hamid M, Yao X, Waugh C, Rosendo Machado S, Li C, Rostron T, et al. Defective Interferon Gamma Production by Tumor-Specific CD8+ T Cells Is Associated With 5'Methylcytosine-Guanine Hypermethylation of Interferon Gamma Promoter. Front Immunol. 2020;11:310 pubmed 出版商
Abd Hamid M, Colin York H, Khalid Alham N, Browne M, Cerundolo L, Chen J, et al. Self-Maintaining CD103+ Cancer-Specific T Cells Are Highly Energetic with Rapid Cytotoxic and Effector Responses. Cancer Immunol Res. 2020;8:203-216 pubmed 出版商
Catapano M, Vergnano M, Romano M, Mahil S, Choon S, Burden A, et al. IL-36 Promotes Systemic IFN-I Responses in Severe Forms of Psoriasis. J Invest Dermatol. 2020;140:816-826.e3 pubmed 出版商
Hagan T, Cortese M, Rouphael N, Boudreau C, Linde C, Maddur M, et al. Antibiotics-Driven Gut Microbiome Perturbation Alters Immunity to Vaccines in Humans. Cell. 2019;178:1313-1328.e13 pubmed 出版商
Findlay E, Currie A, Zhang A, Ovciarikova J, Young L, Stevens H, et al. Exposure to the antimicrobial peptide LL-37 produces dendritic cells optimized for immunotherapy. Oncoimmunology. 2019;8:1608106 pubmed 出版商
Hunegnaw R, Mushtaq Z, Enyindah Asonye G, Hoang T, Robert Guroff M. Alveolar Macrophage Dysfunction and Increased PD-1 Expression During Chronic SIV Infection of Rhesus Macaques. Front Immunol. 2019;10:1537 pubmed 出版商
Ding L, Kim H, Wang Q, Kearns M, Jiang T, Ohlson C, et al. PARP Inhibition Elicits STING-Dependent Antitumor Immunity in Brca1-Deficient Ovarian Cancer. Cell Rep. 2018;25:2972-2980.e5 pubmed 出版商
de Mingo Pulido Á, Gardner A, Hiebler S, Soliman H, Rugo H, Krummel M, et al. TIM-3 Regulates CD103+ Dendritic Cell Function and Response to Chemotherapy in Breast Cancer. Cancer Cell. 2018;33:60-74.e6 pubmed 出版商
Asai A, Okajima F, Nakagawa K, Ibusuki D, Tanimura K, Nakajima Y, et al. Phosphatidylcholine hydroperoxide-induced THP-1 cell adhesion to intracellular adhesion molecule-1. J Lipid Res. 2009;50:957-65 pubmed 出版商
Gurer C, Strowig T, Brilot F, Pack M, Trumpfheller C, Arrey F, et al. Targeting the nuclear antigen 1 of Epstein-Barr virus to the human endocytic receptor DEC-205 stimulates protective T-cell responses. Blood. 2008;112:1231-9 pubmed 出版商
Sadhu C, Ting H, Lipsky B, Hensley K, Garcia Martinez L, Simon S, et al. CD11c/CD18: novel ligands and a role in delayed-type hypersensitivity. J Leukoc Biol. 2007;81:1395-403 pubmed
产品信息
抗原 :
CD11c
Apps. Abbrev. :
流式细胞仪
目录 :
301637
克隆 :
3.9
产品 :
亮紫色650™抗人类CD11c
抗体亚型 :
Mouse IgG1, κ
其他名称 :
整合素αX亚单位, CR4, p150, ITGAX
规格 :
25试验
价格(美元) :
220美元
反应物种 :
Human, Cynomolgus, Rhesus
克隆性 :
单克隆
宿主 :
小鼠
共轭标签/标签/标记 :
BV650
应用注释 :
Clone 3.9 preferentially binds the activated form of CD11c, is specific for the I domain of CD11c, and is able to partially block the binding of CD11c and ICAM-4. 3.9 binding is divalent cation dependent 12 . While analyzing blood, it is best to use heparin as the anti-coagulant and not EDTA. Since the ability of clone 3.9 to bind to its target is divalent cation dependent, the usage of EDTA as an anti-coagulant may be detrimental to staining due to its chelating properties. Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections 4 , and functional assays 5,6 . The LEAF purified antibody (Endotoxin 0.1 EU/ug, Azide-Free, 0.2 um filtered) is recommended for functional assays (Cat. No. 301616). For highly sensitive assays, we recommend Ultra-LEAF purified antibody (Cat. No. 301632) with a lower endotoxin limit than standard LEAF purified antibodies (Endotoxin 0.01 EU/ug).
更多信息或购买 :
BioLegend 产品网页
公司信息
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品，旨在加速生命科学领域的研发工作。