产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
纯化抗人类CD18
目录 :
302102
规格 :
100微克
价格 :
112美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
TS1/18
反应物种 :
人类, 小鼠
应用 :
中和反应, 流式细胞仪, 抑制或激活实验
更多信息或购买 :
文章摘录数: 22
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 人类; 图 s1
Matsumoto K, Kurasawa T, Yoshimoto K, Suzuki K, Takeuchi T. Identification of neutrophil β2-integrin LFA-1 as a potential mechanistic biomarker in ANCA-associated vasculitis via microarray and validation analyses. Arthritis Res Ther. 2021;23:136 pubmed 出版商
  • 流式细胞仪; 人类; 图 1b
Buffone A, Anderson N, Hammer D. Migration against the direction of flow is LFA-1-dependent in human hematopoietic stem and progenitor cells. J Cell Sci. 2018;131: pubmed 出版商
  • 流式细胞仪; 人类; 图 3a
Janesch P, Rouha H, Weber S, Malafa S, Gross K, Maierhofer B, et al. Selective sensitization of human neutrophils to LukGH mediated cytotoxicity by Staphylococcus aureus and IL-8. J Infect. 2017;74:473-483 pubmed 出版商
  • 抑制或激活实验; 人类; 图 s6b
Park R, Wang T, Koundakjian D, Hultquist J, Lamothe Molina P, Monel B, et al. A genome-wide CRISPR screen identifies a restricted set of HIV host dependency factors. Nat Genet. 2017;49:193-203 pubmed 出版商
  • 抑制或激活实验; 人类; 图 5c
Yeap W, Wong K, Shimasaki N, Teo E, Quek J, Yong H, et al. CD16 is indispensable for antibody-dependent cellular cytotoxicity by human monocytes. Sci Rep. 2016;6:34310 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 8a
Guo H, Cranert S, Lu Y, Zhong M, Zhang S, Chen J, et al. Deletion of Slam locus in mice reveals inhibitory role of SLAM family in NK cell responses regulated by cytokines and LFA-1. J Exp Med. 2016;213:2187-207 pubmed 出版商
  • 流式细胞仪; 人类; 图 2a
Curtis B, Roman A, Sullivan M, Raven C, Larison J, Weitekamp L. Two cases of maternal alloimmunization against human neutrophil alloantigen-4b, one causing severe alloimmune neonatal neutropenia. Transfusion. 2016;56:101-6 pubmed 出版商
  • 流式细胞仪; 人类; 图 5
Difranco K, Johnson Farley N, Bertino J, Elson D, Vega B, Belinka B, et al. LFA-1-targeting Leukotoxin (LtxA; Leukothera®) causes lymphoma tumor regression in a humanized mouse model and requires caspase-8 and Fas to kill malignant lymphocytes. Leuk Res. 2015;39:649-56 pubmed 出版商
  • 抑制或激活实验; 人类
Marinho C, Azeredo E, Torrentes Carvalho A, Marins Dos Santos A, Kubelka C, de Souza L, et al. Down-regulation of complement receptors on the surface of host monocyte even as in vitro complement pathway blocking interferes in dengue infection. PLoS ONE. 2014;9:e102014 pubmed 出版商
  • 流式细胞仪; 人类
Lozano Fernández T, Ballester Antxordoki L, Pérez Temprano N, Rojas E, Sanz D, Iglesias Gaspar M, et al. Potential impact of metal oxide nanoparticles on the immune system: The role of integrins, L-selectin and the chemokine receptor CXCR4. Nanomedicine. 2014;10:1301-10 pubmed 出版商
Chong D, Rebeyrol C, José R, Williams A, Brown J, Scotton C, et al. ICAM-1 and ICAM-2 Are Differentially Expressed and Up-Regulated on Inflamed Pulmonary Epithelium, but Neither ICAM-2 nor LFA-1: ICAM-1 Are Required for Neutrophil Migration Into the Airways In Vivo. Front Immunol. 2021;12:691957 pubmed 出版商
Myint P, Ito A, Appiah M, Obeng G, Darkwah S, Kawamoto E, et al. Irisin supports integrin-mediated cell adhesion of lymphocytes. Biochem Biophys Rep. 2021;26:100977 pubmed 出版商
Kolev M, West E, Kunz N, Chauss D, Moseman E, Rahman J, et al. Diapedesis-Induced Integrin Signaling via LFA-1 Facilitates Tissue Immunity by Inducing Intrinsic Complement C3 Expression in Immune Cells. Immunity. 2020;52:513-527.e8 pubmed 出版商
Ristow L, Tran V, Schwartz K, Pankratz L, Mehle A, Sauer J, et al. The Extracellular Domain of the β2 Integrin β Subunit (CD18) Is Sufficient for Escherichia coli Hemolysin and Aggregatibacter actinomycetemcomitans Leukotoxin Cytotoxic Activity. MBio. 2019;10: pubmed 出版商
Lee C, Zhang H, Singh S, Koo L, Kabat J, Tsang H, et al. C/EBPδ drives interactions between human MAIT cells and endothelial cells that are important for extravasation. elife. 2018;7: pubmed 出版商
Li N, Yang H, Wang M, Lü S, Zhang Y, Long M. Ligand-specific binding forces of LFA-1 and Mac-1 in neutrophil adhesion and crawling. Mol Biol Cell. 2018;29:408-418 pubmed 出版商
Hosoki K, Nakamura A, Nagao M, Hiraguchi Y, Tanida H, Tokuda R, et al. Staphylococcus aureus directly activates eosinophils via platelet-activating factor receptor. J Leukoc Biol. 2012;92:333-41 pubmed 出版商
Sommaggio R, Cohnen A, Watzl C, Costa C. Multiple receptors trigger human NK cell-mediated cytotoxicity against porcine chondrocytes. J Immunol. 2012;188:2075-83 pubmed 出版商
Chakrabarty S, Snyder J, Shen J, Azmi H, Hu P, Chen Q, et al. Human CD14hi monocytes and myeloid dendritic cells provide a cell contact-dependent costimulatory signal for early CD40 ligand expression. Blood. 2011;117:1585-94 pubmed 出版商
Tran D, Glass D, Uzel G, Darnell D, Spalding C, Holland S, et al. Analysis of adhesion molecules, target cells, and role of IL-2 in human FOXP3+ regulatory T cell suppressor function. J Immunol. 2009;182:2929-38 pubmed 出版商
Kanda H, Newton R, Klein R, Morita Y, Gunn M, Rosen S. Autotaxin, an ectoenzyme that produces lysophosphatidic acid, promotes the entry of lymphocytes into secondary lymphoid organs. Nat Immunol. 2008;9:415-23 pubmed 出版商
Nakayama H, Yoshizaki F, Prinetti A, Sonnino S, Mauri L, Takamori K, et al. Lyn-coupled LacCer-enriched lipid rafts are required for CD11b/CD18-mediated neutrophil phagocytosis of nonopsonized microorganisms. J Leukoc Biol. 2008;83:728-41 pubmed
产品信息
抗原 :
CD18
Apps. Abbrev. :
流式细胞仪, 中和
目录 :
302102
克隆 :
TS1/18
产品 :
纯化抗人类CD18
抗体亚型 :
Mouse IgG1, κ
其他名称 :
Integrin β2 subunit, LFA -1 β subunit, β2 integrin, ITGB2
规格 :
100微克
价格(美元) :
112美元
反应物种 :
人类
克隆性 :
单克隆
宿主 :
小鼠
共轭标签/标签/标记 :
PURE
应用注释 :
Additional reported applications (for the relevant formats) include: inhibition of cell adhesion and migration 3,4 . The Ultra-LEAF purified antibody (Endotoxin 0.01 EU/ug, Azide-Free, 0.2 um filtered) (Cat. No. 302116) is recommended for functional assays.
更多信息或购买 :
公司信息
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品,旨在加速生命科学领域的研发工作。