产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
Alexa Fluor系列荧光染料®647抗人类CD45
目录 :
304018
规格 :
100试验
价格 :
265美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
AF647
克隆名称 :
HI30
反应物种 :
人类, 小鼠
应用 :
免疫细胞化学, 流式细胞仪, 免疫组化-冰冻切片, mass cytometry
更多信息或购买 :
文章摘录数: 62
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 人类; 图 1f, s1b
Wu X, Xia T, Shin W, Yu K, Jung W, Herrmann A, et al. Viral Mimicry of Interleukin-17A by SARS-CoV-2 ORF8. MBio. 2022;13:e0040222 pubmed 出版商
  • mass cytometry; 人类; 图 4e
Ingelfinger F, Krishnarajah S, Kramer M, Utz S, Galli E, Lutz M, et al. Single-cell profiling of myasthenia gravis identifies a pathogenic T cell signature. Acta Neuropathol. 2021;141:901-915 pubmed 出版商
  • 流式细胞仪; 人类
Vavassori V, Mercuri E, Marcovecchio G, Castiello M, Schiroli G, Albano L, et al. Modeling, optimization, and comparable efficacy of T cell and hematopoietic stem cell gene editing for treating hyper-IgM syndrome. EMBO Mol Med. 2021;13:e13545 pubmed 出版商
  • 流式细胞仪; 人类; 图 5a
Harro C, Perez Sanz J, Costich T, Payne K, Anadon C, Chaurio R, et al. Methyltransferase inhibitors restore SATB1 protective activity against cutaneous T cell lymphoma in mice. J Clin Invest. 2021;131: pubmed 出版商
  • 流式细胞仪; 人类; 图 s1
Katano I, Ito R, Kawai K, Takahashi T. Improved Detection of in vivo Human NK Cell-Mediated Antibody-Dependent Cellular Cytotoxicity Using a Novel NOG-FcγR-Deficient Human IL-15 Transgenic Mouse. Front Immunol. 2020;11:532684 pubmed 出版商
  • 免疫细胞化学; 人类; 10 ug/ml; 图 2b
Ortiz Otero N, Marshall J, Lash B, King M. Chemotherapy-induced release of circulating-tumor cells into the bloodstream in collective migration units with cancer-associated fibroblasts in metastatic cancer patients. BMC Cancer. 2020;20:873 pubmed 出版商
  • 流式细胞仪; 人类; 图 1b
Stary V, Wolf B, Unterleuthner D, List J, Talic M, Laengle J, et al. Short-course radiotherapy promotes pro-inflammatory macrophages via extracellular vesicles in human rectal cancer. J Immunother Cancer. 2020;8: pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 图 9a
Kaaij M, van Tok M, Blijdorp I, Ambarus C, Stock M, Pots D, et al. Transmembrane TNF drives osteoproliferative joint inflammation reminiscent of human spondyloarthritis. J Exp Med. 2020;217: pubmed 出版商
  • 流式细胞仪; 人类
Wong S, Lenzini S, Cooper M, Mooney D, Shin J. Soft extracellular matrix enhances inflammatory activation of mesenchymal stromal cells to induce monocyte production and trafficking. Sci Adv. 2020;6:eaaw0158 pubmed 出版商
  • mass cytometry; 人类; 图 1b, 1d, s2
Leylek R, Alcántara Hernández M, Lanzar Z, Lüdtke A, Perez O, Reizis B, et al. Integrated Cross-Species Analysis Identifies a Conserved Transitional Dendritic Cell Population. Cell Rep. 2019;29:3736-3750.e8 pubmed 出版商
  • 免疫细胞化学; 人类; 1:250; 图 2a
Bokun V, Moore J, Moore R, Smallcombe C, Harford T, Rezaee F, et al. Respiratory syncytial virus exhibits differential tropism for distinct human placental cell types with Hofbauer cells acting as a permissive reservoir for infection. PLoS ONE. 2019;14:e0225767 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s19b
  • 流式细胞仪; 人类; 图 s14b
Stewart B, Ferdinand J, Young M, Mitchell T, Loudon K, Riding A, et al. Spatiotemporal immune zonation of the human kidney. Science. 2019;365:1461-1466 pubmed 出版商
  • 流式细胞仪; 人类; 图 1a
Allden S, Ogger P, Ghai P, McErlean P, Hewitt R, Toshner R, et al. The Transferrin Receptor CD71 Delineates Functionally Distinct Airway Macrophage Subsets during Idiopathic Pulmonary Fibrosis. Am J Respir Crit Care Med. 2019;: pubmed 出版商
  • mass cytometry; 人类; 图 s1
Fernandez I, Baxter R, Garcia Perez J, Vendrame E, Ranganath T, Kong D, et al. A novel human IL2RB mutation results in T and NK cell-driven immune dysregulation. J Exp Med. 2019;216:1255-1267 pubmed 出版商
  • 流式细胞仪; 人类; 图 s3
Lim S, Kim J, Jeon S, Shin M, Kwon J, Kim T, et al. Defective Localization With Impaired Tumor Cytotoxicity Contributes to the Immune Escape of NK Cells in Pancreatic Cancer Patients. Front Immunol. 2019;10:496 pubmed 出版商
  • 流式细胞仪; 人类; 图 1c
Montel Hagen A, Seet C, Li S, Chick B, Zhu Y, Chang P, et al. Organoid-Induced Differentiation of Conventional T Cells from Human Pluripotent Stem Cells. Cell Stem Cell. 2019;24:376-389.e8 pubmed 出版商
  • 流式细胞仪; 人类; 表 s1
Dias J, Boulouis C, Gorin J, van den Biggelaar R, Lal K, Gibbs A, et al. The CD4-CD8- MAIT cell subpopulation is a functionally distinct subset developmentally related to the main CD8+ MAIT cell pool. Proc Natl Acad Sci U S A. 2018;115:E11513-E11522 pubmed 出版商
  • 流式细胞仪; 人类; 图 s3b
Arnold I, Artola Borán M, Tallón de Lara P, Kyburz A, Taube C, OTTEMANN K, et al. Eosinophils suppress Th1 responses and restrict bacterially induced gastrointestinal inflammation. J Exp Med. 2018;215:2055-2072 pubmed 出版商
  • 流式细胞仪; 人类; 图 9b
Casey A, Sinha A, Singhania R, Livingstone J, Waterhouse P, Tharmapalan P, et al. Mammary molecular portraits reveal lineage-specific features and progenitor cell vulnerabilities. J Cell Biol. 2018;217:2951-2974 pubmed 出版商
  • 流式细胞仪; 人类; 图 1a
Bujko A, Atlasy N, Landsverk O, Richter L, Yaqub S, Horneland R, et al. Transcriptional and functional profiling defines human small intestinal macrophage subsets. J Exp Med. 2018;215:441-458 pubmed 出版商
  • 流式细胞仪; 人类; 图 1c
Herndler Brandstetter D, Shan L, Yao Y, Stecher C, Plajer V, Lietzenmayer M, et al. Humanized mouse model supports development, function, and tissue residency of human natural killer cells. Proc Natl Acad Sci U S A. 2017;114:E9626-E9634 pubmed 出版商
  • 流式细胞仪; 人类; 图 6c
Daley D, Mani V, Mohan N, Akkad N, Ochi A, Heindel D, et al. Dectin 1 activation on macrophages by galectin 9 promotes pancreatic carcinoma and peritumoral immune tolerance. Nat Med. 2017;23:556-567 pubmed 出版商
  • 流式细胞仪; 人类; 图 1a
Wei C, Mei J, Tang L, Liu Y, Li D, Li M, et al. 1-Methyl-tryptophan attenuates regulatory T cells differentiation due to the inhibition of estrogen-IDO1-MRC2 axis in endometriosis. Cell Death Dis. 2016;7:e2489 pubmed 出版商
  • 流式细胞仪; 人类; 图 3a
Faivre V, Lukaszewicz A, Payen D. Downregulation of Blood Monocyte HLA-DR in ICU Patients Is Also Present in Bone Marrow Cells. PLoS ONE. 2016;11:e0164489 pubmed 出版商
  • 免疫细胞化学; 人类; 图 s7
Jung Y, Riven I, Feigelson S, Kartvelishvily E, Tohya K, Miyasaka M, et al. Three-dimensional localization of T-cell receptors in relation to microvilli using a combination of superresolution microscopies. Proc Natl Acad Sci U S A. 2016;113:E5916-E5924 pubmed
  • 流式细胞仪; 人类; 图 s1
Landtwing V, Raykova A, Pezzino G, Beziat V, Marcenaro E, Graf C, et al. Cognate HLA absence in trans diminishes human NK cell education. J Clin Invest. 2016;126:3772-3782 pubmed 出版商
  • 流式细胞仪; 人类; 图 1a
Bal S, Bernink J, Nagasawa M, Groot J, Shikhagaie M, Golebski K, et al. IL-1?, IL-4 and IL-12 control the fate of group 2 innate lymphoid cells in human airway inflammation in the lungs. Nat Immunol. 2016;17:636-45 pubmed 出版商
  • 流式细胞仪; 人类; 图 4
Jackson J, Taylor J, Witek M, Hunsucker S, Waugh J, Fedoriw Y, et al. Microfluidics for the detection of minimal residual disease in acute myeloid leukemia patients using circulating leukemic cells selected from blood. Analyst. 2016;141:640-51 pubmed 出版商
  • 流式细胞仪; 人类
Bendall S, Simonds E, Qiu P, Amir E, Krutzik P, Finck R, et al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science. 2011;332:687-96 pubmed 出版商
Wang H, Chen L, Qi L, Jiang N, Zhang Z, Guo H, et al. A Single-Cell Atlas of Tumor-Infiltrating Immune Cells in Pancreatic Ductal Adenocarcinoma. Mol Cell Proteomics. 2022;21:100258 pubmed 出版商
Frensch M, Jäger C, Müller P, Tadić A, Wilhelm I, Wehrum S, et al. Bacterial lectin BambL acts as a B cell superantigen. Cell Mol Life Sci. 2021;78:8165-8186 pubmed 出版商
Mehta A, Cheney E, Hartl C, Pantelidou C, Oliwa M, Castrillon J, et al. Targeting immunosuppressive macrophages overcomes PARP inhibitor resistance in BRCA1-associated triple-negative breast cancer. Nat Cancer. 2021;2:66-82 pubmed 出版商
Bade R, Schehr J, Emamekhoo H, Gibbs B, Rodems T, Mannino M, et al. Development and initial clinical testing of a multiplexed circulating tumor cell assay in patients with clear cell renal cell carcinoma. Mol Oncol. 2021;15:2330-2344 pubmed 出版商
Olah M, Menon V, Habib N, Taga M, Ma Y, Yung C, et al. Single cell RNA sequencing of human microglia uncovers a subset associated with Alzheimer's disease. Nat Commun. 2020;11:6129 pubmed 出版商
Raimondi L, Raimondi F, Di Benedetto L, Cimino G, Spinelli G. PD-L1 Expression on Circulating Tumour Cells May Be Predictive of Response to Regorafenib in Patients Diagnosed with Chemorefractory Metastatic Colorectal Cancer. Int J Mol Sci. 2020;21: pubmed 出版商
Yee de León J, Soto García B, Aráiz Hernández D, Delgado Balderas J, Esparza M, Aguilar Avelar C, et al. Characterization of a novel automated microfiltration device for the efficient isolation and analysis of circulating tumor cells from clinical blood samples. Sci Rep. 2020;10:7543 pubmed 出版商
Razvag Y, Neve Oz Y, Sajman J, Yakovian O, Reches M, Sherman E. T Cell Activation through Isolated Tight Contacts. Cell Rep. 2019;29:3506-3521.e6 pubmed 出版商
Sakamoto S, Kagawa S, Kuwada K, Ito A, Kajioka H, Kakiuchi Y, et al. Intraperitoneal cancer-immune microenvironment promotes peritoneal dissemination of gastric cancer. Oncoimmunology. 2019;8:e1671760 pubmed 出版商
Aguilar Avelar C, Soto García B, Aráiz Hernández D, Yee de León J, Esparza M, Chacón F, et al. High-Throughput Automated Microscopy of Circulating Tumor Cells. Sci Rep. 2019;9:13766 pubmed 出版商
Koyama M, Mukhopadhyay P, Schuster I, Henden A, Hülsdünker J, Varelias A, et al. MHC Class II Antigen Presentation by the Intestinal Epithelium Initiates Graft-versus-Host Disease and Is Influenced by the Microbiota. Immunity. 2019;51:885-898.e7 pubmed 出版商
Bravo San Pedro J, Sica V, Martins I, Pol J, Loos F, Maiuri M, et al. Acyl-CoA-Binding Protein Is a Lipogenic Factor that Triggers Food Intake and Obesity. Cell Metab. 2019;30:754-767.e9 pubmed 出版商
Janning M, Kobus F, Babayan A, Wikman H, Velthaus J, Bergmann S, et al. Determination of PD-L1 Expression in Circulating Tumor Cells of NSCLC Patients and Correlation with Response to PD-1/PD-L1 Inhibitors. Cancers (Basel). 2019;11: pubmed 出版商
Garcia J, Wozny A, Geiguer F, Delherme A, Barthelemy D, Merle P, et al. Profiling of circulating tumor DNA in plasma of non-small cell lung cancer patients, monitoring of epidermal growth factor receptor p.T790M mutated allelic fraction using beads, emulsion, amplification, and magnetics companion assay and evaluation in. Cancer Med. 2019;8:3685-3697 pubmed 出版商
Luong Gardiol N, Siddiqui I, Pizzitola I, Jeevan Raj B, Charmoy M, Huang Y, et al. γ-Catenin-Dependent Signals Maintain BCR-ABL1+ B Cell Acute Lymphoblastic Leukemia. Cancer Cell. 2019;35:649-663.e10 pubmed 出版商
Gonzales Aloy E, Connerty P, Salik B, Liu B, Woo A, Haber M, et al. miR-101 suppresses the development of MLL-rearranged acute myeloid leukemia. Haematologica. 2019;104:e296-e299 pubmed 出版商
Lin J, Izar B, Wang S, Yapp C, Mei S, Shah P, et al. Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes. elife. 2018;7: pubmed 出版商
Olah M, Patrick E, Villani A, Xu J, White C, Ryan K, et al. A transcriptomic atlas of aged human microglia. Nat Commun. 2018;9:539 pubmed 出版商
Chen S, Sun Y, Neoh K, Chen A, Li W, Yang X, et al. Microfluidic assay of circulating endothelial cells in coronary artery disease patients with angina pectoris. PLoS ONE. 2017;12:e0181249 pubmed 出版商
Futia G, Schlaepfer I, Qamar L, Behbakht K, Gibson E. Statistical performance of image cytometry for DNA, lipids, cytokeratin, & CD45 in a model system for circulation tumor cell detection. Cytometry A. 2017;91:662-674 pubmed 出版商
Gierahn T, Wadsworth M, Hughes T, Bryson B, Butler A, Satija R, et al. Seq-Well: portable, low-cost RNA sequencing of single cells at high throughput. Nat Methods. 2017;14:395-398 pubmed 出版商
Zhong W, Yi Q, Xu B, Li S, Wang T, Liu F, et al. ORP4L is essential for T-cell acute lymphoblastic leukemia cell survival. Nat Commun. 2016;7:12702 pubmed 出版商
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Bushway M, Gerber S, Fenton B, Miller R, Lord E, Murphy S. Morphological and phenotypic analyses of the human placenta using whole mount immunofluorescence. Biol Reprod. 2014;90:110 pubmed 出版商
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产品信息
抗原 :
CD45
Apps. Abbrev. :
流式细胞仪
目录 :
304018
克隆 :
HI30
产品 :
Alexa Fluor系列荧光染料®647抗人类CD45
抗体亚型 :
Mouse IgG1, κ
其他名称 :
LCA, T200
规格 :
100试验
价格(美元) :
265美元
反应物种 :
人类
克隆性 :
单克隆
宿主 :
小鼠
共轭标签/标签/标记 :
A647
应用注释 :
Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen tissue sections and formalin-fixed paraffin-embedded tissue sections 9 , inhibition of CD45 functions 4 , immunofluorescence 11 , Western blotting 3 , and spatial biology (IBEX) 16,17 . It was found that the HI30 clone and the 2D1 clone can cross block each other s binding.
更多信息或购买 :
公司信息
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品,旨在加速生命科学领域的研发工作。