产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
PE抗人类CD262(DR5, TRAIL-R2)
目录 :
307405
规格 :
25试验
价格 :
134美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
PE
克隆名称 :
DJR2-4(7-8)
反应物种 :
人类, 小鼠
应用 :
流式细胞仪
更多信息或购买 :
文章摘录数: 15
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 1:200; 图 1h
Jeong D, Kim H, Kim H, Kang M, Jung H, Oh Y, et al. Soluble Fas ligand drives autoantibody-induced arthritis by binding to DR5/TRAIL-R2. elife. 2021;10: pubmed 出版商
  • 流式细胞仪; 人类; 图 s2g
Chollat Namy M, Ben Safta Saadoun T, Haferssas D, Meurice G, Chouaib S, Thiery J. The pharmalogical reactivation of p53 function improves breast tumor cell lysis by granzyme B and NK cells through induction of autophagy. Cell Death Dis. 2019;10:695 pubmed 出版商
  • 流式细胞仪; 人类; 图 4
Braun F, Mathur R, Sehgal L, Wilkie Grantham R, Chandra J, Berkova Z, et al. Inhibition of methyltransferases accelerates degradation of cFLIP and sensitizes B-cell lymphoma cells to TRAIL-induced apoptosis. PLoS ONE. 2015;10:e0117994 pubmed 出版商
Grayson K, Jyotsana N, Ortiz Otero N, King M. Overcoming TRAIL-resistance by sensitizing prostate cancer 3D spheroids with taxanes. PLoS ONE. 2021;16:e0246733 pubmed 出版商
Grayson K, Hope J, Wang W, Reinhart King C, King M. Taxanes Sensitize Prostate Cancer Cells to TRAIL-Induced Apoptotic Synergy via Endoplasmic Reticulum Stress. Mol Cancer Ther. 2021;20:833-845 pubmed 出版商
Ng W, Gong C, Yan X, Si G, Fang C, Wang L, et al. Targeting CD155 by rediocide-A overcomes tumour immuno-resistance to natural killer cells. Pharm Biol. 2021;59:47-53 pubmed 出版商
Wu Y, Kimura Y, Okamoto T, Matsuhisa K, Asada R, Saito A, et al. Inflammatory bowel disease-associated ubiquitin ligase RNF183 promotes lysosomal degradation of DR5 and TRAIL-induced caspase activation. Sci Rep. 2019;9:20301 pubmed 出版商
Brin E, Wu K, Dagostino E, Meng Chiang Kuo M, He Y, Shia W, et al. TRAIL stabilization and cancer cell sensitization to its pro-apoptotic activity achieved through genetic fusion with arginine deiminase. Oncotarget. 2018;9:36914-36928 pubmed 出版商
Yao C, Ni Z, Gong C, Zhu X, Wang L, Xu Z, et al. Rocaglamide enhances NK cell-mediated killing of non-small cell lung cancer cells by inhibiting autophagy. Autophagy. 2018;14:1831-1844 pubmed 出版商
Kolluri K, Alifrangis C, Kumar N, Ishii Y, Price S, Michaut M, et al. Loss of functional BAP1 augments sensitivity to TRAIL in cancer cells. elife. 2018;7: pubmed 出版商
Vunnam N, Campbell Bezat C, Lewis A, Sachs J. Death Receptor 5 Activation Is Energetically Coupled to Opening of the Transmembrane Domain Dimer. Biophys J. 2017;113:381-392 pubmed 出版商
Choi Y, Lee J, Lee H, Chang D, Sung P, Jung M, et al. Liver injury in acute hepatitis A is associated with decreased frequency of regulatory T cells caused by Fas-mediated apoptosis. Gut. 2015;64:1303-13 pubmed 出版商
Magnussen G, Ree Rosnes A, Shahzidi S, Dong H, Emilsen E, Engesæter B, et al. Synthetic retinoid CD437 induces apoptosis and acts synergistically with TRAIL receptor-2 agonist in malignant melanoma. Biochem Biophys Res Commun. 2012;420:516-22 pubmed 出版商
Stolfi C, Caruso R, Franzè E, Rizzo A, Rotondi A, Monteleone I, et al. 2-methoxy-5-amino-N-hydroxybenzamide sensitizes colon cancer cells to TRAIL-induced apoptosis by regulating death receptor 5 and survivin expression. Mol Cancer Ther. 2011;10:1969-81 pubmed 出版商
Canestraro M, Galimberti S, Savli H, Palumbo G, Tibullo D, Nagy B, et al. Synergistic antiproliferative effect of arsenic trioxide combined with bortezomib in HL60 cell line and primary blasts from patients affected by myeloproliferative disorders. Cancer Genet Cytogenet. 2010;199:110-20 pubmed 出版商
产品信息
抗原 :
CD262
Apps. Abbrev. :
流式细胞仪
目录 :
307405
克隆 :
DJR2-4(7-8)
产品 :
PE抗人类CD262(DR5, TRAIL-R2)
抗体亚型 :
Mouse IgG1, κ
其他名称 :
TRAIL-R2, KILLER, TRICK2, TNFRSF10B, Ly98, CD262
规格 :
25试验
价格(美元) :
134美元
反应物种 :
人类
克隆性 :
单克隆
宿主 :
小鼠
共轭标签/标签/标记 :
PE
免疫原 :
Extracellular domain of DR5-human IgG1 Fc fusion protein
应用注释 :
Additional reported applications (for the relevant formats) include: The DJR2-4 antibody is useful for immunofluorescent staining and flow cytometric analysis of DR5/TRAIL-R2 receptor expression. For most successful immunofluorescent staining results, it may be important to maximize signal over background by using a relatively bright fluorochrome-antibody conjugate (Cat. No. 307406) or by using a high sensitivity, three-layer staining technique (e.g., including a biotinylated antibody (Cat. No. 307404) or biotinylated anti-mouse IgG second step (Cat. No. 405303), followed by SAv-PE (Cat. No. 405204)).
更多信息或购买 :
公司信息
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品,旨在加速生命科学领域的研发工作。