产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
LEAF™纯化抗人类CD282(Toll样受体2)
目录 :
309709
规格 :
100微克
价格 :
230美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
TL2.1
反应物种 :
人类
应用 :
免疫印迹, 中和反应, 免疫沉淀, 流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 抑制或激活实验
更多信息或购买 :
BioLegend 产品网页
文章摘录数: 8
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 1a
Hally K, La Flamme A, Larsen P, Harding S. Platelet Toll-like receptor (TLR) expression and TLR-mediated platelet activation in acute myocardial infarction. Thromb Res. 2017;158:8-15 pubmed 出版商
  • 抑制或激活实验; 人类; 图 3a
Cheng W, van Asten S, Burns L, Evans H, Walter G, Hashim A, et al. Periodontitis-associated pathogens P. gingivalis and A. actinomycetemcomitans activate human CD14(+) monocytes leading to enhanced Th17/IL-17 responses. Eur J Immunol. 2016;46:2211-21 pubmed 出版商
Miani M, Le Naour J, Waeckel Enée E, Verma S, Straube M, Emond P, et al. Gut Microbiota-Stimulated Innate Lymphoid Cells Support ?-Defensin 14 Expression in Pancreatic Endocrine Cells, Preventing Autoimmune Diabetes. Cell Metab. 2018;: pubmed 出版商
Shen Y, Guo D, Weng L, Wang S, Ma Z, Yang Y, et al. Tumor-derived exosomes educate dendritic cells to promote tumor metastasis via HSP72/HSP105-TLR2/TLR4 pathway. Oncoimmunology. 2017;6:e1362527 pubmed 出版商
Chu C, Yu Y, Kung Y, Liao P, Liu K, Tseng Y, et al. The immunomodulatory activity of meningococcal lipoprotein Ag473 depends on the conformation made up of the lipid and protein moieties. PLoS ONE. 2012;7:e40873 pubmed 出版商
Pagano S, Satta N, Werling D, Offord V, de Moerloose P, Charbonney E, et al. Anti-apolipoprotein A-1 IgG in patients with myocardial infarction promotes inflammation through TLR2/CD14 complex. J Intern Med. 2012;272:344-57 pubmed 出版商
West X, Malinin N, Merkulova A, Tischenko M, Kerr B, Borden E, et al. Oxidative stress induces angiogenesis by activating TLR2 with novel endogenous ligands. Nature. 2010;467:972-6 pubmed 出版商
Chambers M, Whelan A, Spallek R, Singh M, Coddeville B, Guerardel Y, et al. Non-acylated Mycobacterium bovis glycoprotein MPB83 binds to TLR1/2 and stimulates production of matrix metalloproteinase 9. Biochem Biophys Res Commun. 2010;400:403-8 pubmed 出版商
产品信息
抗原 :
CD282
Apps. Abbrev. :
流式细胞仪, 中和, 免疫组化-P, 免疫组化-F, 免疫沉淀, 西方墨点法
目录 :
309709
克隆 :
TL2.1
产品 :
LEAF™纯化抗人类CD282(Toll样受体2)
抗体亚型 :
Mouse IgG2a, κ
其他名称 :
Toll样受体2, TIL4, CD282
规格 :
100微克
价格(美元) :
230美元
反应物种 :
人类
克隆性 :
单克隆
宿主 :
小鼠
共轭标签/标签/标记 :
LEAF
免疫原 :
Human TLR2-transfected CHO cells
应用注释 :
The TL2.1 antibody is useful for blocking studies. It has been reported to block TLR2 agonist-induced cellular activation. Additional reported applications (for the relevant formats) include: inhibition of PGP activity and blocking of cytokine production 1,3,7 , immunoprecipitation 1 , immunohistochemistry of 4% paraformaldehyde-fixed frozen sections 2 and immunohistochemistry of HOPE-fixed (HEPES-glutamic acid buffer-mediated organic solvent protection effect) paraffin-embedded sections 4 , and Western blotting 2 . The LEAF™ purified antibody (Endotoxin 0.1 EU/μg, Azide-Free, 0.2 μm filtered) is recommended for functional assays (Cat. No. 309709). For highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 309716) with a lower endotoxin limit than standard LEAF™ purified antibodies (Endotoxin 0.01 EU/µg).
更多信息或购买 :
BioLegend 产品网页
公司信息
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品，旨在加速生命科学领域的研发工作。