产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
PE抗人类HLA-A, B, C
目录 :
311406
规格 :
100试验
价格 :
216美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
PE
克隆名称 :
W6/32
反应物种 :
人类, 猕猴
应用 :
流式细胞仪
更多信息或购买 :
文章摘录数: 33
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 人类; 1:100; 图 s4b
Taniguchi H, Caeser R, Chavan S, Zhan Y, Chow A, Manoj P, et al. WEE1 inhibition enhances the antitumor immune response to PD-L1 blockade by the concomitant activation of STING and STAT1 pathways in SCLC. Cell Rep. 2022;39:110814 pubmed 出版商
  • 流式细胞仪; 人类; 1:100; 图 2c, 5f, s3e
Wolpaw A, Grossmann L, Dessau J, Dong M, Aaron B, Brafford P, et al. Epigenetic state determines inflammatory sensing in neuroblastoma. Proc Natl Acad Sci U S A. 2022;119: pubmed 出版商
  • 流式细胞仪; 人类; 1:75; 图 2b
Yamamoto K, Venida A, Yano J, Biancur D, Kakiuchi M, Gupta S, et al. Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I. Nature. 2020;581:100-105 pubmed 出版商
Lee P, Klaeger S, Le P, Korthauer K, Cheng J, Ananthapadmanabhan V, et al. Reversal of viral and epigenetic HLA class I repression in Merkel cell carcinoma. J Clin Invest. 2022;132: pubmed 出版商
Song C, Wang L, Li Q, Liao B, Qiao W, Li Q, et al. Generation of individualized immunocompatible endothelial cells from HLA-I-matched human pluripotent stem cells. Stem Cell Res Ther. 2022;13:48 pubmed 出版商
Feola S, Haapala M, Peltonen K, Capasso C, Martins B, Antignani G, et al. PeptiCHIP: A Microfluidic Platform for Tumor Antigen Landscape Identification. ACS Nano. 2021;15:15992-16010 pubmed 出版商
Chida K, Sakurai Y, Ohtani A, Masuda T, Ohtsuki S, Tanaka H, et al. Proteomics Analysis of Lymphatic Metastasis-Related Proteins Using Highly Metastatic Human Melanoma Cells Originated by Sequential in Vivo Implantation. Biol Pharm Bull. 2021;44:1551-1556 pubmed 出版商
Izumi K, Shindo T, Ngo H, Nakayama Hosoya K, Akahane K, Tamai M, et al. KIR3DL1 Allotype-Dependent Modulation of NK Cell Immunity against Chronic Myeloid Leukemia. Immunohorizons. 2021;5:687-702 pubmed 出版商
Portillo A, Hogg R, Poznanski S, Rojas E, Cashell N, Hammill J, et al. Expanded human NK cells armed with CAR uncouple potent anti-tumor activity from off-tumor toxicity against solid tumors. iScience. 2021;24:102619 pubmed 出版商
Zhu X, Chudnovskiy A, Baudrier L, Prizer B, Liu Y, Ostendorf B, et al. Functional Genomics In Vivo Reveal Metabolic Dependencies of Pancreatic Cancer Cells. Cell Metab. 2021;33:211-221.e6 pubmed 出版商
Nazari Shafti T, Neuber S, Duran A, Exarchos V, Beez C, Meyborg H, et al. MiRNA Profiles of Extracellular Vesicles Secreted by Mesenchymal Stromal Cells-Can They Predict Potential Off-Target Effects?. Biomolecules. 2020;10: pubmed 出版商
Leite N, Sintov E, Meissner T, Brehm M, Greiner D, Harlan D, et al. Modeling Type 1 Diabetes In Vitro Using Human Pluripotent Stem Cells. Cell Rep. 2020;32:107894 pubmed 出版商
Iraqi M, Edri A, Greenshpan Y, Kundu K, Bolel P, Cahana A, et al. N-Glycans Mediate the Ebola Virus-GP1 Shielding of Ligands to Immune Receptors and Immune Evasion. Front Cell Infect Microbiol. 2020;10:48 pubmed 出版商
Miller M, Douglass J, Hwang M, Skora A, Murphy M, Papadopoulos N, et al. An engineered antibody fragment targeting mutant β-catenin via major histocompatibility complex I neoantigen presentation. J Biol Chem. 2019;294:19322-19334 pubmed 出版商
Oshchepkova A, Neumestova A, Matveeva V, Artemyeva L, Morozova K, Kiseleva E, et al. Cytochalasin-B-Inducible Nanovesicle Mimics of Natural Extracellular Vesicles That Are Capable of Nucleic Acid Transfer. Micromachines (Basel). 2019;10: pubmed 出版商
Martufi M, Good R, Rapiteanu R, Schmidt T, Patili E, Tvermosegaard K, et al. Single-Step, High-Efficiency CRISPR-Cas9 Genome Editing in Primary Human Disease-Derived Fibroblasts. CRISPR J. 2019;2:31-40 pubmed 出版商
Javitt A, Barnea E, Kramer M, Wolf Levy H, Levin Y, Admon A, et al. Pro-inflammatory Cytokines Alter the Immunopeptidome Landscape by Modulation of HLA-B Expression. Front Immunol. 2019;10:141 pubmed 出版商
Poznanski S, Nham T, Chew M, Lee A, Hammill J, Fan I, et al. Expanded CD56superbrightCD16+ NK Cells from Ovarian Cancer Patients Are Cytotoxic against Autologous Tumor in a Patient-Derived Xenograft Murine Model. Cancer Immunol Res. 2018;6:1174-1185 pubmed 出版商
Mitchell K, Barreyro L, Todorova T, Taylor S, Antony Debré I, Narayanagari S, et al. IL1RAP potentiates multiple oncogenic signaling pathways in AML. J Exp Med. 2018;215:1709-1727 pubmed 出版商
Wang B, Lin Y, Hu Y, Shan W, Liu S, Xu Y, et al. mTOR inhibition improves the immunomodulatory properties of human bone marrow mesenchymal stem cells by inducing COX-2 and PGE2. Stem Cell Res Ther. 2017;8:292 pubmed 出版商
Herbring V, Bäucker A, Trowitzsch S, Tampe R. A dual inhibition mechanism of herpesviral ICP47 arresting a conformationally thermostable TAP complex. Sci Rep. 2016;6:36907 pubmed 出版商
Salzberger W, Garcia Beltran W, Dugan H, Gubbala S, Simoneau C, Gressens S, et al. Influence of Glycosylation Inhibition on the Binding of KIR3DL1 to HLA-B*57:01. PLoS ONE. 2015;10:e0145324 pubmed 出版商
Blees A, Reichel K, Trowitzsch S, Fisette O, Bock C, Abele R, et al. Assembly of the MHC I peptide-loading complex determined by a conserved ionic lock-switch. Sci Rep. 2015;5:17341 pubmed 出版商
Skora A, Douglass J, Hwang M, Tam A, Blosser R, Gabelli S, et al. Generation of MANAbodies specific to HLA-restricted epitopes encoded by somatically mutated genes. Proc Natl Acad Sci U S A. 2015;112:9967-72 pubmed 出版商
Grossmann N, Vakkasoglu A, Hulpke S, Abele R, Gaudet R, Tampé R. Mechanistic determinants of the directionality and energetics of active export by a heterodimeric ABC transporter. Nat Commun. 2014;5:5419 pubmed 出版商
Vantourout P, Willcox C, Turner A, Swanson C, Haque Y, Sobolev O, et al. Immunological visibility: posttranscriptional regulation of human NKG2D ligands by the EGF receptor pathway. Sci Transl Med. 2014;6:231ra49 pubmed 出版商
Hu W, Zheng R, Cui H, Yue D, Wang Y, Jiang Y. Effects of bortezomib in sensitizing human prostate cancer cell lines to NK-mediated cytotoxicity. Asian J Androl. 2012;14:695-702 pubmed 出版商
Meissner T, Li A, Liu Y, Gagnon E, Kobayashi K. The nucleotide-binding domain of NLRC5 is critical for nuclear import and transactivation activity. Biochem Biophys Res Commun. 2012;418:786-91 pubmed 出版商
Merlo A, Turrini R, Bobisse S, Zamarchi R, Alaggio R, Dolcetti R, et al. Virus-specific cytotoxic CD4+ T cells for the treatment of EBV-related tumors. J Immunol. 2010;184:5895-902 pubmed 出版商
Laing B, Ross D, Meyer S, Campbell P, Halpin A, West L, et al. Glutaraldehyde treatment of allograft tissue decreases allosensitization after the Norwood procedure. J Thorac Cardiovasc Surg. 2010;139:1402-8 pubmed 出版商
Lünemann A, Lunemann J, Roberts S, Messmer B, Barreira da Silva R, Raine C, et al. Human NK cells kill resting but not activated microglia via NKG2D- and NKp46-mediated recognition. J Immunol. 2008;181:6170-7 pubmed
McLoughlin R, Lee J, Kasper D, Tzianabos A. IFN-gamma regulated chemokine production determines the outcome of Staphylococcus aureus infection. J Immunol. 2008;181:1323-32 pubmed
Takahara M, Miyai M, Tomiyama M, Mutou M, Nicol A, Nieda M. Copulsing tumor antigen-pulsed dendritic cells with zoledronate efficiently enhance the expansion of tumor antigen-specific CD8+ T cells via Vgamma9gammadelta T cell activation. J Leukoc Biol. 2008;83:742-54 pubmed
产品信息
抗原 :
HLA-A
Apps. Abbrev. :
流式细胞仪
目录 :
311406
克隆 :
W6/32
产品 :
PE抗人类HLA-A, B, C
抗体亚型 :
Mouse IgG2a, κ
其他名称 :
Major Histocompatibility Class I, MHC class I
规格 :
100试验
价格(美元) :
216美元
反应物种 :
Human, Cynomolgus, Rhesus
克隆性 :
单克隆
宿主 :
小鼠
共轭标签/标签/标记 :
PE
应用注释 :
Clone W6/32 recognizes residues in the N terminus of the human 2-microglobulin molecule 21 . Additional reported applications (for the relevant formats) include: immunoprecipitaton 2 , Western blotting (non-reducing) 3 , immunohistochemical staining of acetone-fixed frozen tissue sections 4,5 , blocking 6,7 , inhibition of NK cell-mediated lysis 10 , and activation 8,9 . Clone W6/32 has been reported not to be suitable for immunohistochemistry on paraffin sections 17 . The LEAF purified antibody (Endotoxin 0.1 EU/ug, Azide-Free, 0.2 um filtered) is recommended for functional assays. For highly sensitive assays, we recommend Ultra-LEAF purified antibody (Cat. No. 311428) with a lower endotoxin limit than standard LEAF purified antibodies (Endotoxin 0.01 EU/ug).
更多信息或购买 :
公司信息
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品,旨在加速生命科学领域的研发工作。