产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
Alexa Fluor系列荧光染料®647抗人类HLA-A, B, C
目录 :
311414
规格 :
100试验
价格 :
242美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
AF647
克隆名称 :
W6/32
反应物种 :
人类, 猕猴
应用 :
流式细胞仪, 抑制或激活实验
更多信息或购买 :
BioLegend 产品网页
文章摘录数: 23
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 人类; 图 s1
Poletto E, Colella P, Pimentel Vera L, Khan S, Tomatsu S, Baldo G, et al. Improved engraftment and therapeutic efficacy by human genome-edited hematopoietic stem cells with Busulfan-based myeloablation. Mol Ther Methods Clin Dev. 2022;25:392-409 pubmed 出版商
  • 抑制或激活实验; 人类; 5 ug/ml; 图 2e
  • 流式细胞仪; 人类; 图 2b
Zhu Y, Xie J, Shi J. Rac1/ROCK-driven membrane dynamics promote natural killer cell cytotoxicity via granzyme-induced necroptosis. BMC Biol. 2021;19:140 pubmed 出版商
  • 流式细胞仪; 人类; 1:75; 图 2b
Yamamoto K, Venida A, Yano J, Biancur D, Kakiuchi M, Gupta S, et al. Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I. Nature. 2020;581:100-105 pubmed 出版商
  • 流式细胞仪; 人类
Merola J, Reschke M, Pierce R, Qin L, Spindler S, Baltazar T, et al. Progenitor-derived human endothelial cells evade alloimmunity by CRISPR/Cas9-mediated complete ablation of MHC expression. JCI Insight. 2019;4: pubmed 出版商
  • 流式细胞仪; 人类; 图 s8
Pavel Dinu M, Wiebking V, Dejene B, Srifa W, Mantri S, Nicolas C, et al. Gene correction for SCID-X1 in long-term hematopoietic stem cells. Nat Commun. 2019;10:1634 pubmed 出版商
  • 流式细胞仪; 人类; 图 s1
Liu R, Merola J, Manes T, Qin L, Tietjen G, Lopez Giraldez F, et al. Interferon-γ converts human microvascular pericytes into negative regulators of alloimmunity through induction of indoleamine 2,3-dioxygenase 1. JCI Insight. 2018;3: pubmed 出版商
  • 流式细胞仪; 人类; 1:50; 图 2a
Barkal A, Weiskopf K, Kao K, Gordon S, Rosental B, Yiu Y, et al. Engagement of MHC class I by the inhibitory receptor LILRB1 suppresses macrophages and is a target of cancer immunotherapy. Nat Immunol. 2018;19:76-84 pubmed 出版商
  • 流式细胞仪; 人类; 图 s1b
Burr M, Sparbier C, Chan Y, Williamson J, Woods K, Beavis P, et al. CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity. Nature. 2017;549:101-105 pubmed 出版商
  • 流式细胞仪; 人类; 图 3c
Reches A, Nachmani D, Berhani O, Duev Cohen A, Shreibman D, Ophir Y, et al. HNRNPR Regulates the Expression of Classical and Nonclassical MHC Class I Proteins. J Immunol. 2016;196:4967-76 pubmed 出版商
Ma A, Motyka B, Gutfreund K, Shi Y, George R. A dendritic cell receptor-targeted chimeric immunotherapeutic protein (C-HBV) for the treatment of chronic hepatitis B. Hum Vaccin Immunother. 2020;16:756-778 pubmed 出版商
Bernson E, Christenson K, Pesce S, Pasanen M, Marcenaro E, Sivori S, et al. Downregulation of HLA Class I Renders Inflammatory Neutrophils More Susceptible to NK Cell-Induced Apoptosis. Front Immunol. 2019;10:2444 pubmed 出版商
Gamage T, Schierding W, Tsai P, Ludgate J, Chamley L, Weeks R, et al. Human trophoblasts are primarily distinguished from somatic cells by differences in the pattern rather than the degree of global CpG methylation. Biol Open. 2018;7: pubmed 出版商
Siciliano V, DiAndreth B, Monel B, Beal J, Huh J, Clayton K, et al. Engineering modular intracellular protein sensor-actuator devices. Nat Commun. 2018;9:1881 pubmed 出版商
Cao J, Brouwer N, Jordanova E, Marinkovic M, van Duinen S, de Waard N, et al. HLA Class I Antigen Expression in Conjunctival Melanoma Is Not Associated With PD-L1/PD-1 Status. Invest Ophthalmol Vis Sci. 2018;59:1005-1015 pubmed 出版商
Turco M, Gardner L, Hughes J, Cindrova Davies T, Gomez M, Farrell L, et al. Long-term, hormone-responsive organoid cultures of human endometrium in a chemically defined medium. Nat Cell Biol. 2017;19:568-577 pubmed 出版商
Thomas L, Vitale L, O Neill T, Dolnick R, Wallace P, Minderman H, et al. Development of a Novel Antibody-Drug Conjugate for the Potential Treatment of Ovarian, Lung, and Renal Cell Carcinoma Expressing TIM-1. Mol Cancer Ther. 2016;15:2946-2954 pubmed
James J, Hurley D, Gamage T, Zhang T, Vather R, Pantham P, et al. Isolation and characterisation of a novel trophoblast side-population from first trimester placentae. Reproduction. 2015;150:449-62 pubmed 出版商
Reichel J, Chadburn A, Rubinstein P, Giulino Roth L, Tam W, Liu Y, et al. Flow sorting and exome sequencing reveal the oncogenome of primary Hodgkin and Reed-Sternberg cells. Blood. 2015;125:1061-72 pubmed 出版商
Porat Shliom N, Weigert R, Donaldson J. Endosomes derived from clathrin-independent endocytosis serve as precursors for endothelial lumen formation. PLoS ONE. 2013;8:e81987 pubmed 出版商
Laing B, Ross D, Meyer S, Campbell P, Halpin A, West L, et al. Glutaraldehyde treatment of allograft tissue decreases allosensitization after the Norwood procedure. J Thorac Cardiovasc Surg. 2010;139:1402-8 pubmed 出版商
Lünemann A, Lunemann J, Roberts S, Messmer B, Barreira da Silva R, Raine C, et al. Human NK cells kill resting but not activated microglia via NKG2D- and NKp46-mediated recognition. J Immunol. 2008;181:6170-7 pubmed
McLoughlin R, Lee J, Kasper D, Tzianabos A. IFN-gamma regulated chemokine production determines the outcome of Staphylococcus aureus infection. J Immunol. 2008;181:1323-32 pubmed
Takahara M, Miyai M, Tomiyama M, Mutou M, Nicol A, Nieda M. Copulsing tumor antigen-pulsed dendritic cells with zoledronate efficiently enhance the expansion of tumor antigen-specific CD8+ T cells via Vgamma9gammadelta T cell activation. J Leukoc Biol. 2008;83:742-54 pubmed
产品信息
抗原 :
HLA-A
Apps. Abbrev. :
流式细胞仪
目录 :
311414
克隆 :
W6/32
产品 :
Alexa Fluor系列荧光染料®647抗人类HLA-A, B, C
抗体亚型 :
Mouse IgG2a, κ
其他名称 :
Major Histocompatibility Class I, MHC class I
规格 :
100试验
价格(美元) :
242美元
反应物种 :
Human, Cynomolgus, Rhesus
克隆性 :
单克隆
宿主 :
小鼠
共轭标签/标签/标记 :
A647
应用注释 :
Clone W6/32 recognizes residues in the N terminus of the human 2-microglobulin molecule 21 . Additional reported applications (for the relevant formats) include: immunoprecipitaton 2 , Western blotting (non-reducing) 3 , immunohistochemical staining of acetone-fixed frozen tissue sections 4,5 , blocking 6,7 , inhibition of NK cell-mediated lysis 10 , and activation 8,9 . Clone W6/32 has been reported not to be suitable for immunohistochemistry on paraffin sections 17 . The LEAF purified antibody (Endotoxin 0.1 EU/ug, Azide-Free, 0.2 um filtered) is recommended for functional assays. For highly sensitive assays, we recommend Ultra-LEAF purified antibody (Cat. No. 311428) with a lower endotoxin limit than standard LEAF purified antibodies (Endotoxin 0.01 EU/ug).
更多信息或购买 :
BioLegend 产品网页
公司信息
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品，旨在加速生命科学领域的研发工作。