产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
Alexa Fluor系列荧光染料®700抗人类HLA-A, B, C
目录 :
311438
规格 :
100试验
价格 :
265美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
AF700
克隆名称 :
W6/32
反应物种 :
人类, 猕猴
应用 :
流式细胞仪, 抑制或激活实验
更多信息或购买 :
BioLegend 产品网页
文章摘录数: 18
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 人类; 图 s1
Poletto E, Colella P, Pimentel Vera L, Khan S, Tomatsu S, Baldo G, et al. Improved engraftment and therapeutic efficacy by human genome-edited hematopoietic stem cells with Busulfan-based myeloablation. Mol Ther Methods Clin Dev. 2022;25:392-409 pubmed 出版商
  • 抑制或激活实验; 人类; 5 ug/ml; 图 2e
  • 流式细胞仪; 人类; 图 2b
Zhu Y, Xie J, Shi J. Rac1/ROCK-driven membrane dynamics promote natural killer cell cytotoxicity via granzyme-induced necroptosis. BMC Biol. 2021;19:140 pubmed 出版商
  • 流式细胞仪; 人类; 1:75; 图 2b
Yamamoto K, Venida A, Yano J, Biancur D, Kakiuchi M, Gupta S, et al. Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I. Nature. 2020;581:100-105 pubmed 出版商
  • 流式细胞仪; 人类
Merola J, Reschke M, Pierce R, Qin L, Spindler S, Baltazar T, et al. Progenitor-derived human endothelial cells evade alloimmunity by CRISPR/Cas9-mediated complete ablation of MHC expression. JCI Insight. 2019;4: pubmed 出版商
  • 流式细胞仪; 人类; 图 s8
Pavel Dinu M, Wiebking V, Dejene B, Srifa W, Mantri S, Nicolas C, et al. Gene correction for SCID-X1 in long-term hematopoietic stem cells. Nat Commun. 2019;10:1634 pubmed 出版商
  • 流式细胞仪; 人类; 图 s1
Liu R, Merola J, Manes T, Qin L, Tietjen G, Lopez Giraldez F, et al. Interferon-γ converts human microvascular pericytes into negative regulators of alloimmunity through induction of indoleamine 2,3-dioxygenase 1. JCI Insight. 2018;3: pubmed 出版商
  • 流式细胞仪; 人类; 1:50; 图 2a
Barkal A, Weiskopf K, Kao K, Gordon S, Rosental B, Yiu Y, et al. Engagement of MHC class I by the inhibitory receptor LILRB1 suppresses macrophages and is a target of cancer immunotherapy. Nat Immunol. 2018;19:76-84 pubmed 出版商
  • 流式细胞仪; 人类; 图 s1b
Burr M, Sparbier C, Chan Y, Williamson J, Woods K, Beavis P, et al. CMTM6 maintains the expression of PD-L1 and regulates anti-tumour immunity. Nature. 2017;549:101-105 pubmed 出版商
  • 流式细胞仪; 人类; 图 3c
Reches A, Nachmani D, Berhani O, Duev Cohen A, Shreibman D, Ophir Y, et al. HNRNPR Regulates the Expression of Classical and Nonclassical MHC Class I Proteins. J Immunol. 2016;196:4967-76 pubmed 出版商
Lim S, Alavi S, Ming Z, Shklovskaya E, Fung C, Stewart A, et al. Melanoma Cell State-Specific Responses to TNFα. Biomedicines. 2021;9: pubmed 出版商
Weisberg S, Carpenter D, Chait M, Dogra P, Gartrell Corrado R, Chen A, et al. Tissue-Resident Memory T Cells Mediate Immune Homeostasis in the Human Pancreas through the PD-1/PD-L1 Pathway. Cell Rep. 2019;29:3916-3932.e5 pubmed 出版商
Koutsakos M, McWilliam H, Aktepe T, Fritzlar S, Illing P, Mifsud N, et al. Downregulation of MHC Class I Expression by Influenza A and B Viruses. Front Immunol. 2019;10:1158 pubmed 出版商
Jung Y, Wang J, Lee E, McGee S, Berry J, Yumoto K, et al. Annexin 2-CXCL12 interactions regulate metastatic cell targeting and growth in the bone marrow. Mol Cancer Res. 2015;13:197-207 pubmed 出版商
Crivello P, Lauterbach N, Zito L, Sizzano F, Toffalori C, Marcon J, et al. Effects of transmembrane region variability on cell surface expression and allorecognition of HLA-DP3. Hum Immunol. 2013;74:970-7 pubmed 出版商
Laing B, Ross D, Meyer S, Campbell P, Halpin A, West L, et al. Glutaraldehyde treatment of allograft tissue decreases allosensitization after the Norwood procedure. J Thorac Cardiovasc Surg. 2010;139:1402-8 pubmed 出版商
Lünemann A, Lunemann J, Roberts S, Messmer B, Barreira da Silva R, Raine C, et al. Human NK cells kill resting but not activated microglia via NKG2D- and NKp46-mediated recognition. J Immunol. 2008;181:6170-7 pubmed
McLoughlin R, Lee J, Kasper D, Tzianabos A. IFN-gamma regulated chemokine production determines the outcome of Staphylococcus aureus infection. J Immunol. 2008;181:1323-32 pubmed
Takahara M, Miyai M, Tomiyama M, Mutou M, Nicol A, Nieda M. Copulsing tumor antigen-pulsed dendritic cells with zoledronate efficiently enhance the expansion of tumor antigen-specific CD8+ T cells via Vgamma9gammadelta T cell activation. J Leukoc Biol. 2008;83:742-54 pubmed
产品信息
抗原 :
HLA-A
Apps. Abbrev. :
流式细胞仪
目录 :
311438
克隆 :
W6/32
产品 :
Alexa Fluor系列荧光染料®700抗人类HLA-A, B, C
抗体亚型 :
Mouse IgG2a, κ
其他名称 :
Major Histocompatibility Class I, MHC class I
规格 :
100试验
价格(美元) :
265美元
反应物种 :
Human, Cynomolgus, Rhesus
克隆性 :
单克隆
宿主 :
小鼠
共轭标签/标签/标记 :
A700
应用注释 :
Clone W6/32 recognizes residues in the N terminus of the human 2-microglobulin molecule 21 . Additional reported applications (for the relevant formats) include: immunoprecipitaton 2 , Western blotting (non-reducing) 3 , immunohistochemical staining of acetone-fixed frozen tissue sections 4,5 , blocking 6,7 , inhibition of NK cell-mediated lysis 10 , and activation 8,9 . Clone W6/32 has been reported not to be suitable for immunohistochemistry on paraffin sections 17 . The LEAF purified antibody (Endotoxin 0.1 EU/ug, Azide-Free, 0.2 um filtered) is recommended for functional assays. For highly sensitive assays, we recommend Ultra-LEAF purified antibody (Cat. No. 311428) with a lower endotoxin limit than standard LEAF purified antibodies (Endotoxin 0.01 EU/ug).
更多信息或购买 :
BioLegend 产品网页
公司信息
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品，旨在加速生命科学领域的研发工作。