产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
纯化抗人类CD284(Toll样受体4)
目录 :
312802
规格 :
100微克
价格 :
197美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
HTA125
反应物种 :
人类
应用 :
免疫印迹, 免疫细胞化学, 中和反应, 流式细胞仪, 免疫组化-冰冻切片, 抑制或激活实验
更多信息或购买 :
文章摘录数: 14
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 人类; 图 2d
Kim J, Jeong J, Jung J, Jeon H, Lee S, Lim J, et al. Immunological characteristics and possible pathogenic role of urinary CD11c+ macrophages in lupus nephritis. Rheumatology (Oxford). 2020;: pubmed 出版商
  • 免疫印迹; 人类; 图 1a
Hally K, La Flamme A, Larsen P, Harding S. Platelet Toll-like receptor (TLR) expression and TLR-mediated platelet activation in acute myocardial infarction. Thromb Res. 2017;158:8-15 pubmed 出版商
  • 流式细胞仪; 人类; 图 4a
Hadadi E, Zhang B, Baidžajevas K, Yusof N, Puan K, Ong S, et al. Differential IL-1? secretion by monocyte subsets is regulated by Hsp27 through modulating mRNA stability. Sci Rep. 2016;6:39035 pubmed 出版商
  • 抑制或激活实验; 人类; 图 2a
An L, Gorman J, Stephens G, Swerdlow B, Warrener P, Bonnell J, et al. Complement C5a induces PD-L1 expression and acts in synergy with LPS through Erk1/2 and JNK signaling pathways. Sci Rep. 2016;6:33346 pubmed 出版商
  • 抑制或激活实验; 人类; 图 3
Pagano S, Carbone F, Burger F, Roth A, Bertolotto M, Pane B, et al. Anti-apolipoprotein A-1 auto-antibodies as active modulators of atherothrombosis. Thromb Haemost. 2016;116:554-64 pubmed 出版商
  • 抑制或激活实验; 人类; 图 3a
Cheng W, van Asten S, Burns L, Evans H, Walter G, Hashim A, et al. Periodontitis-associated pathogens P. gingivalis and A. actinomycetemcomitans activate human CD14(+) monocytes leading to enhanced Th17/IL-17 responses. Eur J Immunol. 2016;46:2211-21 pubmed 出版商
Stephens M, Liao S, von der Weid P. Ultra-purification of Lipopolysaccharides reveals species-specific signalling bias of TLR4: importance in macrophage function. Sci Rep. 2021;11:1335 pubmed 出版商
Bennstein S, Weinhold S, Manser A, Scherenschlich N, Noll A, Raba K, et al. Umbilical cord blood-derived ILC1-like cells constitute a novel precursor for mature KIR+NKG2A- NK cells. elife. 2020;9: pubmed 出版商
Yoon J, Um H, Jang J, Bae Y, Park W, Kim H, et al. Eosinophil Activation by Toll-Like Receptor 4 Ligands Regulates Macrophage Polarization. Front Cell Dev Biol. 2019;7:329 pubmed 出版商
Poznanski S, Nham T, Chew M, Lee A, Hammill J, Fan I, et al. Expanded CD56superbrightCD16+ NK Cells from Ovarian Cancer Patients Are Cytotoxic against Autologous Tumor in a Patient-Derived Xenograft Murine Model. Cancer Immunol Res. 2018;6:1174-1185 pubmed 出版商
Alcántara Hernández M, Leylek R, Wagar L, Engleman E, Keler T, Marinkovich M, et al. High-Dimensional Phenotypic Mapping of Human Dendritic Cells Reveals Interindividual Variation and Tissue Specialization. Immunity. 2017;47:1037-1050.e6 pubmed 出版商
Manukyan G, Papajik T, Gajdos P, Mikulkova Z, Urbanová R, Gabcova G, et al. Neutrophils in chronic lymphocytic leukemia are permanently activated and have functional defects. Oncotarget. 2017;8:84889-84901 pubmed 出版商
Bhattacharyya S, Gill R, Chen M, Zhang F, Linhardt R, Dudeja P, et al. Toll-like receptor 4 mediates induction of the Bcl10-NFkappaB-interleukin-8 inflammatory pathway by carrageenan in human intestinal epithelial cells. J Biol Chem. 2008;283:10550-8 pubmed 出版商
Chavakis E, Hain A, Vinci M, Carmona G, Bianchi M, Vajkoczy P, et al. High-mobility group box 1 activates integrin-dependent homing of endothelial progenitor cells. Circ Res. 2007;100:204-12 pubmed
产品信息
抗原 :
CD284
Apps. Abbrev. :
流式细胞仪, 免疫组化-F, 免疫细胞化学, 西方墨点法, 中和
目录 :
312802
克隆 :
HTA125
产品 :
纯化抗人类CD284(Toll样受体4)
抗体亚型 :
Mouse IgG2a, κ
其他名称 :
Toll样受体4, Toll样受体4, TLR-4, CD284
规格 :
100微克
价格(美元) :
197美元
反应物种 :
人类
克隆性 :
单克隆
宿主 :
小鼠
共轭标签/标签/标记 :
PURE
免疫原 :
Ba/F3 cell line expressing human TLR4
应用注释 :
Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen sections 4 , immunofluorescence microscopy 6 , Western blotting 10 , and in vitro blocking of LPS-induced cytokine production 2,3,7,9 . This clone was tested in-house and does not work on formalin fixed paraffin-embedded (FFPE) tissue. For most successful immunofluorescent staining results, it may be important to maximize signal over background by using a relatively bright fluorochrome-antibody conjugate (Cat. No. 312806) or by using a high sensitivity, three-layer staining technique (e.g., including a biotinylated antibody (Cat. No. 312804) or biotinylated anti-mouse IgG second step (Cat. No. 405303), followed by SAv-PE (Cat. No. 405204). The Ultra-LEAF purified antibody (Endotoxin 0.01 EU/ug, Azide-Free, 0.2 um filtered) is recommended for functional assays (Cat. No. 312813 312814).
更多信息或购买 :
公司信息
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品,旨在加速生命科学领域的研发工作。