产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
纯化抗人类CD117(C-kit)
目录 :
313202
规格 :
100微克
价格 :
176美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
104D2
反应物种 :
African green monkey, 人类, 小鼠
应用 :
免疫细胞化学, 免疫沉淀, 流式细胞仪, 其他, mass cytometry
更多信息或购买 :
文章摘录数: 36
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 人类; 图 1b, 1d
Ryu S, Lee E, Kim D, Kim Y, Chung D, Kim J, et al. Reduction of circulating innate lymphoid cell progenitors results in impaired cytokine production by innate lymphoid cells in patients with lupus nephritis. Arthritis Res Ther. 2020;22:63 pubmed 出版商
  • mass cytometry; 人类; 图 1b, 1d, s2
Leylek R, Alcántara Hernández M, Lanzar Z, Lüdtke A, Perez O, Reizis B, et al. Integrated Cross-Species Analysis Identifies a Conserved Transitional Dendritic Cell Population. Cell Rep. 2019;29:3736-3750.e8 pubmed 出版商
  • 流式细胞仪; 人类; 图 ex1
Ardain A, Domingo Gonzalez R, Das S, Kazer S, Howard N, Singh A, et al. Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis. Nature. 2019;: pubmed 出版商
  • 流式细胞仪; 人类; 1 ug/ml; 图 6a
Duan S, Koziol White C, Jester W, Nycholat C, Macauley M, Panettieri R, et al. CD33 recruitment inhibits IgE-mediated anaphylaxis and desensitizes mast cells to allergen. J Clin Invest. 2019;129:1387-1401 pubmed 出版商
  • 流式细胞仪; 人类; 图 1a
Jeffery H, McDowell P, Lutz P, Wawman R, Roberts S, Bagnall C, et al. Human intrahepatic ILC2 are IL-13positive amphiregulinpositive and their frequency correlates with model of end stage liver disease score. PLoS ONE. 2017;12:e0188649 pubmed 出版商
  • 流式细胞仪; 人类; 图 3a
Herndler Brandstetter D, Shan L, Yao Y, Stecher C, Plajer V, Lietzenmayer M, et al. Humanized mouse model supports development, function, and tissue residency of human natural killer cells. Proc Natl Acad Sci U S A. 2017;114:E9626-E9634 pubmed 出版商
  • 流式细胞仪; 人类; 1:20; 图 ED7c
Britschgi A, Duss S, Kim S, Couto J, Brinkhaus H, Koren S, et al. The Hippo kinases LATS1 and 2 control human breast cell fate via crosstalk with ERα. Nature. 2017;541:541-545 pubmed 出版商
  • 流式细胞仪; African green monkey; 1:100; 图 1
Williams J, Dean A, Lankford S, Criswell T, Badlani G, Andersson K. Determinates of muscle precursor cell therapy efficacy in a nonhuman primate model of intrinsic urinary sphincter deficiency. Stem Cell Res Ther. 2017;8:1 pubmed 出版商
  • 其他; 人类; 图 2
  • 流式细胞仪; 人类; 图 2
Jackson J, Taylor J, Witek M, Hunsucker S, Waugh J, Fedoriw Y, et al. Microfluidics for the detection of minimal residual disease in acute myeloid leukemia patients using circulating leukemic cells selected from blood. Analyst. 2016;141:640-51 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s2d
Okoye Okafor U, Bartholdy B, Cartier J, Gao E, Pietrak B, Rendina A, et al. New IDH1 mutant inhibitors for treatment of acute myeloid leukemia. Nat Chem Biol. 2015;11:878-86 pubmed 出版商
  • 流式细胞仪; 人类; 图 2c
Bai H, Liu Y, Xie Y, Hoyle D, Brodsky R, Cheng L, et al. Definitive Hematopoietic Multipotent Progenitor Cells Are Transiently Generated From Hemogenic Endothelial Cells in Human Pluripotent Stem Cells. J Cell Physiol. 2016;231:1065-76 pubmed 出版商
  • 流式细胞仪; 人类; 图 1
Hines W, Yaswen P, Bissell M. Modelling breast cancer requires identification and correction of a critical cell lineage-dependent transduction bias. Nat Commun. 2015;6:6927 pubmed 出版商
  • 流式细胞仪; 人类
Axelsson Robertson R, Ju J, Kim H, Zumla A, Maeurer M. Mycobacterium tuberculosis-specific and MHC class I-restricted CD8+ T-cells exhibit a stem cell precursor-like phenotype in patients with active pulmonary tuberculosis. Int J Infect Dis. 2015;32:13-22 pubmed 出版商
  • 流式细胞仪; 人类
Cruse G, Beaven M, Music S, Bradding P, Gilfillan A, Metcalfe D. The CD20 homologue MS4A4 directs trafficking of KIT toward clathrin-independent endocytosis pathways and thus regulates receptor signaling and recycling. Mol Biol Cell. 2015;26:1711-27 pubmed 出版商
  • 流式细胞仪; 人类
Mandl M, Schmitz S, Weber C, Hristov M. Characterization of the CD14++CD16+ monocyte population in human bone marrow. PLoS ONE. 2014;9:e112140 pubmed 出版商
  • 流式细胞仪; 人类
Bendall S, Simonds E, Qiu P, Amir E, Krutzik P, Finck R, et al. Single-cell mass cytometry of differential immune and drug responses across a human hematopoietic continuum. Science. 2011;332:687-96 pubmed 出版商
Ganan Gomez I, Yang H, Ma F, Montalban Bravo G, Thongon N, Marchica V, et al. Stem cell architecture drives myelodysplastic syndrome progression and predicts response to venetoclax-based therapy. Nat Med. 2022;28:557-567 pubmed 出版商
Leylek R, Alcántara Hernández M, Granja J, Chavez M, Perez K, Diaz O, et al. Chromatin Landscape Underpinning Human Dendritic Cell Heterogeneity. Cell Rep. 2020;32:108180 pubmed 出版商
Dinh H, Eggert T, Meyer M, Zhu Y, Olingy C, Llewellyn R, et al. Coexpression of CD71 and CD117 Identifies an Early Unipotent Neutrophil Progenitor Population in Human Bone Marrow. Immunity. 2020;53:319-334.e6 pubmed 出版商
Cytlak U, Resteu A, Pagan S, Green K, Milne P, Maisuria S, et al. Differential IRF8 Transcription Factor Requirement Defines Two Pathways of Dendritic Cell Development in Humans. Immunity. 2020;53:353-370.e8 pubmed 出版商
Ma W, Lee J, Backenroth D, Zhou Y, Bush E, Sims P, et al. Single cell RNA-Seq reveals pre-cDCs fate determined by transcription factor combinatorial dose. BMC Mol Cell Biol. 2019;20:20 pubmed 出版商
Lowinus T, Heidel F, Bose T, Nimmagadda S, Schnöder T, Cammann C, et al. Memantine potentiates cytarabine-induced cell death of acute leukemia correlating with inhibition of Kv1.3 potassium channels, AKT and ERK1/2 signaling. Cell Commun Signal. 2019;17:5 pubmed 出版商
Blake L, Thomas S, Blischak J, Hsiao C, Chavarria C, Myrthil M, et al. A comparative study of endoderm differentiation in humans and chimpanzees. Genome Biol. 2018;19:162 pubmed 出版商
Ortiz A, Flynn J, DiNapoli S, Vujkovic Cvijin I, Starke C, Lai S, et al. Experimental microbial dysbiosis does not promote disease progression in SIV-infected macaques. Nat Med. 2018;24:1313-1316 pubmed 出版商
Jokela T, Engelsen A, Rybicka A, Pelissier Vatter F, Garbe J, Miyano M, et al. Microenvironment-Induced Non-sporadic Expression of the AXL and cKIT Receptors Are Related to Epithelial Plasticity and Drug Resistance. Front Cell Dev Biol. 2018;6:41 pubmed 出版商
Vigneault P, Naud P, Qi X, Xiao J, Villeneuve L, Davis D, et al. Calcium-dependent potassium channels control proliferation of cardiac progenitor cells and bone marrow-derived mesenchymal stem cells. J Physiol. 2018;596:2359-2379 pubmed 出版商
Evrard M, Kwok I, Chong S, Teng K, Becht E, Chen J, et al. Developmental Analysis of Bone Marrow Neutrophils Reveals Populations Specialized in Expansion, Trafficking, and Effector Functions. Immunity. 2018;48:364-379.e8 pubmed 出版商
Vargas Hernandez A, Mace E, Zimmerman O, Zerbe C, Freeman A, Rosenzweig S, et al. Ruxolitinib partially reverses functional natural killer cell deficiency in patients with signal transducer and activator of transcription 1 (STAT1) gain-of-function mutations. J Allergy Clin Immunol. 2018;141:2142-2155.e5 pubmed 出版商
Lee B, Mace E. Acquisition of cell migration defines NK cell differentiation from hematopoietic stem cell precursors. Mol Biol Cell. 2017;28:3573-3581 pubmed 出版商
Kyoizumi S, Kubo Y, Kajimura J, Yoshida K, Hayashi T, Nakachi K, et al. Fate Decision Between Group 3 Innate Lymphoid and Conventional NK Cell Lineages by Notch Signaling in Human Circulating Hematopoietic Progenitors. J Immunol. 2017;199:2777-2793 pubmed 出版商
Abud E, Ramirez R, Martinez E, Healy L, Nguyen C, Newman S, et al. iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases. Neuron. 2017;94:278-293.e9 pubmed 出版商
Obata Y, Horikawa K, Takahashi T, Akieda Y, Tsujimoto M, Fletcher J, et al. Oncogenic signaling by Kit tyrosine kinase occurs selectively on the Golgi apparatus in gastrointestinal stromal tumors. Oncogene. 2017;36:3661-3672 pubmed 出版商
Guo M, Nandakumar S, Ulirsch J, Zekavat S, Buenrostro J, Natarajan P, et al. Comprehensive population-based genome sequencing provides insight into hematopoietic regulatory mechanisms. Proc Natl Acad Sci U S A. 2017;114:E327-E336 pubmed 出版商
Oeztuerk Winder F, Guinot A, Ochalek A, Ventura J. Regulation of human lung alveolar multipotent cells by a novel p38α MAPK/miR-17-92 axis. EMBO J. 2012;31:3431-41 pubmed 出版商
Guo A, Janic B, Sheng J, Falck J, Roman R, Edwards P, et al. The cytochrome P450 4A/F-20-hydroxyeicosatetraenoic acid system: a regulator of endothelial precursor cells derived from human umbilical cord blood. J Pharmacol Exp Ther. 2011;338:421-9 pubmed 出版商
Nagano M, Yamashita T, Hamada H, Ohneda K, Kimura K, Nakagawa T, et al. Identification of functional endothelial progenitor cells suitable for the treatment of ischemic tissue using human umbilical cord blood. Blood. 2007;110:151-60 pubmed
产品信息
抗原 :
CD117
Apps. Abbrev. :
流式细胞仪, CyTOF®, 免疫细胞化学, 免疫沉淀
目录 :
313202
克隆 :
104D2
产品 :
纯化抗人类CD117(C-kit)
抗体亚型 :
Mouse IgG1, κ
其他名称 :
Stem cell factor receptor, c-kit, mast cell growth factor receptor, steel factor receptor
规格 :
100微克
价格(美元) :
176美元
反应物种 :
人类
克隆性 :
单克隆
宿主 :
小鼠
共轭标签/标签/标记 :
PURE
免疫原 :
MOLM-1 megakaryocytic cell line
应用注释 :
The 104D2 antibody does not block binding of c-Kit ligand. Additional reported applications (for the relevant formats) include: immunoprecipitation 1 , immunofluorescence microscopy 1 , and spatial biology (IBEX) 4,5 .
更多信息或购买 :
公司信息
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品,旨在加速生命科学领域的研发工作。