产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
纯化抗人类CD3
目录 :
317301
规格 :
25微克
价格 :
30美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
鼠单克隆抗体-CD3
反应物种 :
人类, 小鼠
应用 :
流式细胞仪, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 抑制或激活实验, 其他
更多信息或购买 :
文章摘录数: 119
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠
Jin Y, Lorvik K, Jin Y, Beck C, Sike A, Persiconi I, et al. Development of STEAP1 targeting chimeric antigen receptor for adoptive cell therapy against cancer. Mol Ther Oncolytics. 2022;26:189-206 pubmed 出版商
  • 流式细胞仪; 人类; 图 2b
Hickman T, Choi E, Whiteman K, Muralidharan S, Pai T, Johnson T, et al. BOXR1030, an anti-GPC3 CAR with exogenous GOT2 expression, shows enhanced T cell metabolism and improved anti-cell line derived tumor xenograft activity. PLoS ONE. 2022;17:e0266980 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s1a
Wang Z, He L, Li W, Xu C, Zhang J, Wang D, et al. GDF15 induces immunosuppression via CD48 on regulatory T cells in hepatocellular carcinoma. J Immunother Cancer. 2021;9: pubmed 出版商
  • 流式细胞仪; 人类
Chiou S, Tseng D, Reuben A, Mallajosyula V, Molina I, Conley S, et al. Global analysis of shared T cell specificities in human non-small cell lung cancer enables HLA inference and antigen discovery. Immunity. 2021;54:586-602.e8 pubmed 出版商
  • 流式细胞仪; 人类; 图 5a, 5c
Harro C, Perez Sanz J, Costich T, Payne K, Anadon C, Chaurio R, et al. Methyltransferase inhibitors restore SATB1 protective activity against cutaneous T cell lymphoma in mice. J Clin Invest. 2021;131: pubmed 出版商
  • 其他; 小鼠
Tseng H, Xiong W, Badeti S, Yang Y, Ma M, Liu T, et al. Efficacy of anti-CD147 chimeric antigen receptors targeting hepatocellular carcinoma. Nat Commun. 2020;11:4810 pubmed 出版商
  • 流式细胞仪; 人类; 图 s3a
Fischer M, Ruhnau J, Schulze J, Obst D, Floel A, Vogelgesang A. Spermine and spermidine modulate T-cell function in older adults with and without cognitive decline ex vivo. Aging (Albany NY). 2020;12:13716-13739 pubmed 出版商
  • 流式细胞仪; 人类; 图 1a
Pecher A, Kettemann F, Asteriti E, Schmid H, Duerr Stoerzer S, Keppeler H, et al. Invariant natural killer T cells are functionally impaired in patients with systemic sclerosis. Arthritis Res Ther. 2019;21:212 pubmed 出版商
  • 流式细胞仪; 人类; 图 1a
Lim S, Kim J, Jeon S, Shin M, Kwon J, Kim T, et al. Defective Localization With Impaired Tumor Cytotoxicity Contributes to the Immune Escape of NK Cells in Pancreatic Cancer Patients. Front Immunol. 2019;10:496 pubmed 出版商
  • 抑制或激活实验; 人类; 5 ug/ml; 图 s10e
Lodygin D, Hermann M, Schweingruber N, Flügel Koch C, Watanabe T, Schlosser C, et al. β-Synuclein-reactive T cells induce autoimmune CNS grey matter degeneration. Nature. 2019;566:503-508 pubmed 出版商
  • 流式细胞仪; 人类; 图 s1a
Muller Durovic B, Grählert J, Devine O, Akbar A, Hess C. CD56-negative NK cells with impaired effector function expand in CMV and EBV co-infected healthy donors with age. Aging (Albany NY). 2019;11:724-740 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 s14a
Tan H, Jegaskanda S, Juno J, Esterbauer R, Wong J, Kelly H, et al. Subdominance and poor intrinsic immunogenicity limit humoral immunity targeting influenza HA stem. J Clin Invest. 2019;129:850-862 pubmed 出版商
  • 流式细胞仪; 人类; 图 s3c
Wiedemann G, Aithal C, Kraechan A, Heise C, Cadilha B, Zhang J, et al. Microphthalmia-Associated Transcription Factor (MITF) Regulates Immune Cell Migration into Melanoma. Transl Oncol. 2019;12:350-360 pubmed 出版商
  • 抑制或激活实验; 人类; 1 ug/ml; 图 8f
Klement J, Paschall A, Redd P, Ibrahim M, Lu C, Yang D, et al. An osteopontin/CD44 immune checkpoint controls CD8+ T cell activation and tumor immune evasion. J Clin Invest. 2018;128:5549-5560 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 图 6d
Jung I, Kim Y, Yu H, Lee M, Kim S, Lee J. CRISPR/Cas9-Mediated Knockout of DGK Improves Antitumor Activities of Human T Cells. Cancer Res. 2018;78:4692-4703 pubmed 出版商
  • 抑制或激活实验; 人类; 图 6a
Yang C, Chiu L, Chang C, Chuang H, Tan T. Induction of DUSP14 ubiquitination by PRMT5-mediated arginine methylation. FASEB J. 2018;:fj201800244RR pubmed 出版商
  • 流式细胞仪; 人类; 图 s4a
Yeo L, Woodwyk A, Sood S, Lorenc A, Eichmann M, Pujol Autonell I, et al. Autoreactive T effector memory differentiation mirrors β cell function in type 1 diabetes. J Clin Invest. 2018;128:3460-3474 pubmed 出版商
  • 流式细胞仪; 人类; 图 2a
Kiani Z, Dupuy F, Bruneau J, Lebouché B, Zhang C, Jackson E, et al. HLA-F on HLA-Null 721.221 Cells Activates Primary NK Cells Expressing the Activating Killer Ig-like Receptor KIR3DS1. J Immunol. 2018;201:113-123 pubmed 出版商
  • 流式细胞仪; 人类; 图 1a
Provine N, Binder B, FitzPatrick M, Schuch A, Garner L, Williamson K, et al. Unique and Common Features of Innate-Like Human Vδ2+ γδT Cells and Mucosal-Associated Invariant T Cells. Front Immunol. 2018;9:756 pubmed 出版商
  • 流式细胞仪; 人类; 图 4a
Jackson E, Zhang C, Kiani Z, Lisovsky I, Tallon B, Del Corpo A, et al. HIV exposed seronegative (HESN) compared to HIV infected individuals have higher frequencies of telomeric Killer Immunoglobulin-like Receptor (KIR) B motifs; Contribution of KIR B motif encoded genes to NK cell responsiveness. PLoS ONE. 2017;12:e0185160 pubmed 出版商
  • 流式细胞仪; 人类
Gaggianesi M, Turdo A, Chinnici A, Lipari E, Apuzzo T, Benfante A, et al. IL4 Primes the Dynamics of Breast Cancer Progression via DUSP4 Inhibition. Cancer Res. 2017;77:3268-3279 pubmed 出版商
  • 流式细胞仪; 人类; 图 3d
Jeffery H, Jeffery L, Lutz P, Corrigan M, Webb G, Hirschfield G, et al. Low-dose interleukin-2 promotes STAT-5 phosphorylation, Treg survival and CTLA-4-dependent function in autoimmune liver diseases. Clin Exp Immunol. 2017;188:394-411 pubmed 出版商
  • 流式细胞仪; 人类; 图 s1a
Martin Gayo E, Cronin J, Hickman T, Ouyang Z, Lindqvist M, Kolb K, et al. Circulating CXCR5+CXCR3+PD-1lo Tfh-like cells in HIV-1 controllers with neutralizing antibody breadth. JCI Insight. 2017;2:e89574 pubmed 出版商
  • 流式细胞仪; 人类; 图 s3a
Aagaard K, Lahon A, Suter M, Arya R, Seferovic M, Vogt M, et al. Primary Human Placental Trophoblasts are Permissive for Zika Virus (ZIKV) Replication. Sci Rep. 2017;7:41389 pubmed 出版商
  • 抑制或激活实验; 人类; 图 2a
  • 流式细胞仪; 人类; 图 2a
Ribeiro S, Tesio M, Ribot J, Macintyre E, Barata J, Silva Santos B. Casein kinase 2 controls the survival of normal thymic and leukemic ?? T cells via promotion of AKT signaling. Leukemia. 2017;31:1603-1610 pubmed 出版商
  • 流式细胞仪; 人类; 图 4b
Ye C, Wang W, Cheng L, Li G, Wen M, Wang Q, et al. Glycosylphosphatidylinositol-Anchored Anti-HIV scFv Efficiently Protects CD4 T Cells from HIV-1 Infection and Deletion in hu-PBL Mice. J Virol. 2017;91: pubmed 出版商
  • 抑制或激活实验; 人类; 图 s4a
Serr I, Fürst R, Ott V, Scherm M, Nikolaev A, Gökmen F, et al. miRNA92a targets KLF2 and the phosphatase PTEN signaling to promote human T follicular helper precursors in T1D islet autoimmunity. Proc Natl Acad Sci U S A. 2016;113:E6659-E6668 pubmed
  • 流式细胞仪; 人类; 图 s1
Isitman G, Tremblay McLean A, Lisovsky I, Bruneau J, Lebouché B, Routy J, et al. NK Cells Expressing the Inhibitory Killer Immunoglobulin-Like Receptors (iKIR) KIR2DL1, KIR2DL3 and KIR3DL1 Are Less Likely to Be CD16+ than Their iKIR Negative Counterparts. PLoS ONE. 2016;11:e0164517 pubmed 出版商
  • 抑制或激活实验; 人类
Jung Y, Riven I, Feigelson S, Kartvelishvily E, Tohya K, Miyasaka M, et al. Three-dimensional localization of T-cell receptors in relation to microvilli using a combination of superresolution microscopies. Proc Natl Acad Sci U S A. 2016;113:E5916-E5924 pubmed
  • 流式细胞仪; 人类; 图 5a
Wahid R, Fresnay S, Levine M, Sztein M. Cross-reactive multifunctional CD4+ T cell responses against Salmonella enterica serovars Typhi, Paratyphi A and Paratyphi B in humans following immunization with live oral typhoid vaccine Ty21a. Clin Immunol. 2016;173:87-95 pubmed 出版商
  • 流式细胞仪; 人类; 图 s6a
Landtwing V, Raykova A, Pezzino G, Beziat V, Marcenaro E, Graf C, et al. Cognate HLA absence in trans diminishes human NK cell education. J Clin Invest. 2016;126:3772-3782 pubmed 出版商
  • 流式细胞仪; 人类; 图 2
Theorell J, Bryceson Y. Analysis of Intracellular Ca(2+) Mobilization in Human NK Cell Subsets by Flow Cytometry. Methods Mol Biol. 2016;1441:117-30 pubmed 出版商
  • 流式细胞仪; 人类; 图 1a
Bal S, Bernink J, Nagasawa M, Groot J, Shikhagaie M, Golebski K, et al. IL-1?, IL-4 and IL-12 control the fate of group 2 innate lymphoid cells in human airway inflammation in the lungs. Nat Immunol. 2016;17:636-45 pubmed 出版商
  • 流式细胞仪; 小鼠
Akhmetzyanova I, Drabczyk M, Neff C, Gibbert K, Dietze K, Werner T, et al. PD-L1 Expression on Retrovirus-Infected Cells Mediates Immune Escape from CD8+ T Cell Killing. PLoS Pathog. 2015;11:e1005224 pubmed 出版商
  • 流式细胞仪; 人类; 图 4
Cichocki F, Cooley S, Davis Z, DeFor T, Schlums H, Zhang B, et al. CD56dimCD57+NKG2C+ NK cell expansion is associated with reduced leukemia relapse after reduced intensity HCT. Leukemia. 2016;30:456-63 pubmed 出版商
  • 流式细胞仪; 人类; 图 2
Leeansyah E, Svärd J, Dias J, Buggert M, Nyström J, Quigley M, et al. Arming of MAIT Cell Cytolytic Antimicrobial Activity Is Induced by IL-7 and Defective in HIV-1 Infection. PLoS Pathog. 2015;11:e1005072 pubmed 出版商
  • 流式细胞仪; 人类; 1:200; 图 s3
Adoro S, Cubillos Ruiz J, Chen X, Deruaz M, Vrbanac V, Song M, et al. IL-21 induces antiviral microRNA-29 in CD4 T cells to limit HIV-1 infection. Nat Commun. 2015;6:7562 pubmed 出版商
  • 流式细胞仪; 人类; 1:200
Lee J, Breton G, Aljoufi A, Zhou Y, PUHR S, Nussenzweig M, et al. Clonal analysis of human dendritic cell progenitor using a stromal cell culture. J Immunol Methods. 2015;425:21-6 pubmed 出版商
  • 抑制或激活实验; 人类; 图 s7
Campia I, Buondonno I, Castella B, Rolando B, Kopecka J, Gazzano E, et al. An Autocrine Cytokine/JAK/STAT-Signaling Induces Kynurenine Synthesis in Multidrug Resistant Human Cancer Cells. PLoS ONE. 2015;10:e0126159 pubmed 出版商
  • 流式细胞仪; 人类; 图 4
Lee J, Breton G, Oliveira T, Zhou Y, Aljoufi A, PUHR S, et al. Restricted dendritic cell and monocyte progenitors in human cord blood and bone marrow. J Exp Med. 2015;212:385-99 pubmed 出版商
  • 流式细胞仪; 人类
Prinz P, Mendler A, Brech D, Masouris I, Oberneder R, Noessner E. NK-cell dysfunction in human renal carcinoma reveals diacylglycerol kinase as key regulator and target for therapeutic intervention. Int J Cancer. 2014;135:1832-41 pubmed 出版商
Naranbhai V, Nathan A, Kaseke C, Berríos C, Khatri A, Choi S, et al. T cell reactivity to the SARS-CoV-2 Omicron variant is preserved in most but not all individuals. Cell. 2022;185:1041-1051.e6 pubmed 出版商
Guo J, Luo N, Ai G, Yang W, Zhu J, Li C, et al. Eradicating tumor in a recurrent cervical cancer patient with autologous tumor-infiltrating lymphocytes and a modified lymphodepleting regimen. J Immunother Cancer. 2022;10: pubmed 出版商
Wilson A, Randall K, Pettitt J, Ellyard J, Blumenthal A, Enders A, et al. Neutrophil extracellular traps and their histones promote Th17 cell differentiation directly via TLR2. Nat Commun. 2022;13:528 pubmed 出版商
Moosmann C, Müller T, Busch D, Schober K. Orthotopic T-cell receptor replacement in primary human T cells using CRISPR-Cas9-mediated homology-directed repair. STAR Protoc. 2022;3:101031 pubmed 出版商
Fu Z, Liu H, Wang L, Yu C, Yang Y, Feng M, et al. A reporter gene assay for determining the biological activity of therapeutic antibodies targeting TIGIT. Acta Pharm Sin B. 2021;11:3925-3934 pubmed 出版商
Malenica I, Adam J, Corgnac S, Mezquita L, Auclin E, Damei I, et al. Integrin-αV-mediated activation of TGF-β regulates anti-tumour CD8 T cell immunity and response to PD-1 blockade. Nat Commun. 2021;12:5209 pubmed 出版商
Cassioli C, Balint S, Compeer E, Felce J, Gamberucci A, Della Bella C, et al. Increasing LFA-1 Expression Enhances Immune Synapse Architecture and T Cell Receptor Signaling in Jurkat E6.1 Cells. Front Cell Dev Biol. 2021;9:673446 pubmed 出版商
Henrick B, Rodriguez L, Lakshmikanth T, Pou C, Henckel E, Arzoomand A, et al. Bifidobacteria-mediated immune system imprinting early in life. Cell. 2021;184:3884-3898.e11 pubmed 出版商
He Y, Yang Z, Zhao C, Xiao Z, Gong Y, Li Y, et al. T-cell receptor (TCR) signaling promotes the assembly of RanBP2/RanGAP1-SUMO1/Ubc9 nuclear pore subcomplex via PKC-θ-mediated phosphorylation of RanGAP1. elife. 2021;10: pubmed 出版商
Herati R, Silva L, Vella L, Muselman A, Alanio C, Bengsch B, et al. Vaccine-induced ICOS+CD38+ circulating Tfh are sensitive biosensors of age-related changes in inflammatory pathways. Cell Rep Med. 2021;2:100262 pubmed 出版商
Willimsky G, Beier C, Immisch L, Papafotiou G, Scheuplein V, Goede A, et al. In vitro proteasome processing of neo-splicetopes does not predict their presentation in vivo. elife. 2021;10: pubmed 出版商
Garcia de Moura R, Covre L, Fantecelle C, Gajardo V, Cunha C, Stringari L, et al. PD-1 Blockade Modulates Functional Activities of Exhausted-Like T Cell in Patients With Cutaneous Leishmaniasis. Front Immunol. 2021;12:632667 pubmed 出版商
Kaufmann M, Evans H, Schaupp A, Engler J, Kaur G, Willing A, et al. Identifying CNS-colonizing T cells as potential therapeutic targets to prevent progression of multiple sclerosis. Med (N Y). 2021;2:296-312.e8 pubmed 出版商
Chevrier S, Zurbuchen Y, Cervia C, Adamo S, Raeber M, de Souza N, et al. A distinct innate immune signature marks progression from mild to severe COVID-19. Cell Rep Med. 2021;2:100166 pubmed 出版商
Hu X, Qie C, Jiang J, Xie X, Chen W, Liu W, et al. M351-0056 is a novel low MW compound modulating the actions of the immune-checkpoint protein VISTA. Br J Pharmacol. 2021;178:1445-1458 pubmed 出版商
Srivastava S, Furlan S, Jaeger Ruckstuhl C, Sarvothama M, Berger C, Smythe K, et al. Immunogenic Chemotherapy Enhances Recruitment of CAR-T Cells to Lung Tumors and Improves Antitumor Efficacy when Combined with Checkpoint Blockade. Cancer Cell. 2021;39:193-208.e10 pubmed 出版商
Carriche G, Almeida L, Stüve P, Velasquez L, Dhillon LaBrooy A, Roy U, et al. Regulating T-cell differentiation through the polyamine spermidine. J Allergy Clin Immunol. 2021;147:335-348.e11 pubmed 出版商
Zavidij O, Haradhvala N, Mouhieddine T, Sklavenitis Pistofidis R, Cai S, Reidy M, et al. Single-cell RNA sequencing reveals compromised immune microenvironment in precursor stages of multiple myeloma. Nat Cancer. 2020;1:493-506 pubmed 出版商
Hsu C, Lin Y, Chang L, Huang S, Huang C, Yang C, et al. Therapeutic Role of Inducible Nitric Oxide Synthase Expressing Myeloid-Derived Suppressor Cells in Acetaminophen-Induced Murine Liver Failure. Front Immunol. 2020;11:574839 pubmed 出版商
Li H, Wu H, Guo Q, Yu H, Xu Y, Yu J, et al. Myeloid-Derived Suppressor Cells Promote the Progression of Primary Membranous Nephropathy by Enhancing Th17 Response. Front Immunol. 2020;11:1777 pubmed 出版商
Leylek R, Alcántara Hernández M, Granja J, Chavez M, Perez K, Diaz O, et al. Chromatin Landscape Underpinning Human Dendritic Cell Heterogeneity. Cell Rep. 2020;32:108180 pubmed 出版商
Mehta N, Maddineni S, Kelly R, Lee R, Hunter S, Silberstein J, et al. An engineered antibody binds a distinct epitope and is a potent inhibitor of murine and human VISTA. Sci Rep. 2020;10:15171 pubmed 出版商
Siegers G, Dutta I, Kang E, Huang J, Köbel M, Postovit L. Aberrantly Expressed Embryonic Protein NODAL Alters Breast Cancer Cell Susceptibility to γδ T Cell Cytotoxicity. Front Immunol. 2020;11:1287 pubmed 出版商
Ghosh S, Di Bartolo V, Tubul L, Shimoni E, Kartvelishvily E, Dadosh T, et al. ERM-Dependent Assembly of T Cell Receptor Signaling and Co-stimulatory Molecules on Microvilli prior to Activation. Cell Rep. 2020;30:3434-3447.e6 pubmed 出版商
Levin S, Evans L, Bort S, Rickel E, Lewis K, Wu R, et al. Novel Immunomodulatory Proteins Generated via Directed Evolution of Variant IgSF Domains. Front Immunol. 2019;10:3086 pubmed 出版商
Sneddon S, Rive C, Ma S, Dick I, Allcock R, Brown S, et al. Identification of a CD8+ T-cell response to a predicted neoantigen in malignant mesothelioma. Oncoimmunology. 2020;9:1684713 pubmed 出版商
Walk J, Sauerwein R. Activatory Receptor NKp30 Predicts NK Cell Activation During Controlled Human Malaria Infection. Front Immunol. 2019;10:2864 pubmed 出版商
Auladell M, Nguyen T, Garcillán B, Mackay F, Kedzierska K, Fox A. Distinguishing naive- from memory-derived human B cells during acute responses. Clin Transl Immunology. 2019;8:e01090 pubmed 出版商
Terzuoli E, Bellan C, Aversa S, Ciccone V, Morbidelli L, Giachetti A, et al. ALDH3A1 Overexpression in Melanoma and Lung Tumors Drives Cancer Stem Cell Expansion, Impairing Immune Surveillance through Enhanced PD-L1 Output. Cancers (Basel). 2019;11: pubmed 出版商
Benabdallah B, Désaulniers Langevin C, Colas C, Li Y, Rousseau G, Guimond J, et al. Natural Killer Cells Prevent the Formation of Teratomas Derived From Human Induced Pluripotent Stem Cells. Front Immunol. 2019;10:2580 pubmed 出版商
Xiong Y, Yi Y, Wang Y, Yang N, Rudd C, Liu H. Ubc9 Interacts with and SUMOylates the TCR Adaptor SLP-76 for NFAT Transcription in T Cells. J Immunol. 2019;203:3023-3036 pubmed 出版商
Welch J, Kaufman T, Stapleton J, Okeoma C. Semen exosomes inhibit HIV infection and HIV-induced proinflammatory cytokine production independent of the activation state of primary lymphocytes. FEBS Lett. 2020;594:695-709 pubmed 出版商
Holbrook A, Peterson H, Bianchi S, Macdonald B, Bredahl E, Belshan M, et al. CD4+ T cell activation and associated susceptibility to HIV-1 infection in vitro increased following acute resistance exercise in human subjects. Physiol Rep. 2019;7:e14234 pubmed 出版商
Escudero Pérez B, Ruibal P, Rottstegge M, Lüdtke A, Port J, Hartmann K, et al. Comparative pathogenesis of Ebola virus and Reston virus infection in humanized mice. JCI Insight. 2019;4: pubmed 出版商
Kujawski M, Li L, Bhattacharya S, Wong P, Lee W, Williams L, et al. Generation of dual specific bivalent BiTEs (dbBIspecific T-cell engaging antibodies) for cellular immunotherapy. BMC Cancer. 2019;19:882 pubmed 出版商
Dutertre C, Becht E, Irac S, Khalilnezhad A, Narang V, Khalilnezhad S, et al. Single-Cell Analysis of Human Mononuclear Phagocytes Reveals Subset-Defining Markers and Identifies Circulating Inflammatory Dendritic Cells. Immunity. 2019;51:573-589.e8 pubmed 出版商
Bertino P, Premeaux T, Fujita T, Haun B, Marciel M, Hoffmann F, et al. Targeting the C-terminus of galectin-9 induces mesothelioma apoptosis and M2 macrophage depletion. Oncoimmunology. 2019;8:1601482 pubmed 出版商
Tripathi T, Yin W, Xue Y, Zurawski S, Fujita H, Hanabuchi S, et al. Central Roles of OX40L-OX40 Interaction in the Induction and Progression of Human T Cell-Driven Acute Graft-versus-Host Disease. Immunohorizons. 2019;3:110-120 pubmed 出版商
Broos K, Lecocq Q, Xavier C, Bridoux J, Nguyen T, Corthals J, et al. Evaluating a Single Domain Antibody Targeting Human PD-L1 as a Nuclear Imaging and Therapeutic Agent. Cancers (Basel). 2019;11: pubmed 出版商
Ardain A, Domingo Gonzalez R, Das S, Kazer S, Howard N, Singh A, et al. Group 3 innate lymphoid cells mediate early protective immunity against tuberculosis. Nature. 2019;: pubmed 出版商
Mayer K, Mall S, Yusufi N, Gosmann D, Steiger K, Russelli L, et al. T-cell functionality testing is highly relevant to developing novel immuno-tracers monitoring T cells in the context of immunotherapies and revealed CD7 as an attractive target. Theranostics. 2018;8:6070-6087 pubmed 出版商
Zhao R, Cheng L, Jiang Z, Wei X, Li B, Wu Q, et al. DNAX-activating protein 10 co-stimulation enhances the anti-tumor efficacy of chimeric antigen receptor T cells. Oncoimmunology. 2019;8:e1509173 pubmed 出版商
Caielli S, Veiga D, Balasubramanian P, Athale S, Domic B, Murat E, et al. A CD4+ T cell population expanded in lupus blood provides B cell help through interleukin-10 and succinate. Nat Med. 2019;25:75-81 pubmed 出版商
Meng Q, Valentini D, Rao M, Dodoo E, Maeurer M. CMV and EBV targets recognized by tumor-infiltrating B lymphocytes in pancreatic cancer and brain tumors. Sci Rep. 2018;8:17079 pubmed 出版商
Mousset C, Hobo W, Ji Y, Fredrix H, De Giorgi V, Allison R, et al. Ex vivo AKT-inhibition facilitates generation of polyfunctional stem cell memory-like CD8+ T cells for adoptive immunotherapy. Oncoimmunology. 2018;7:e1488565 pubmed 出版商
Bluhm J, Kieback E, Marino S, Oden F, Westermann J, Chmielewski M, et al. CAR T Cells with Enhanced Sensitivity to B Cell Maturation Antigen for the Targeting of B Cell Non-Hodgkin's Lymphoma and Multiple Myeloma. Mol Ther. 2018;26:1906-1920 pubmed 出版商
Bae E, Seo H, Kim B, Choi J, Jeon I, Shin K, et al. Activation of NKT Cells in an Anti-PD-1-Resistant Tumor Model Enhances Antitumor Immunity by Reinvigorating Exhausted CD8 T Cells. Cancer Res. 2018;78:5315-5326 pubmed 出版商
Yarzabek B, Zaitouna A, Olson E, Silva G, Geng J, Geretz A, et al. Variations in HLA-B cell surface expression, half-life and extracellular antigen receptivity. elife. 2018;7: pubmed 出版商
Boutboul D, Kuehn H, Van de Wyngaert Z, Niemela J, Callebaut I, Stoddard J, et al. Dominant-negative IKZF1 mutations cause a T, B, and myeloid cell combined immunodeficiency. J Clin Invest. 2018;128:3071-3087 pubmed 出版商
Seo N, Shirakura Y, Tahara Y, Momose F, Harada N, Ikeda H, et al. Activated CD8+ T cell extracellular vesicles prevent tumour progression by targeting of lesional mesenchymal cells. Nat Commun. 2018;9:435 pubmed 出版商
Johnston H, Carter M, Larrayoz M, Clarke J, Garbis S, Oscier D, et al. Proteomics Profiling of CLL Versus Healthy B-cells Identifies Putative Therapeutic Targets and a Subtype-independent Signature of Spliceosome Dysregulation. Mol Cell Proteomics. 2018;17:776-791 pubmed 出版商
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产品信息
抗原 :
CD3
Apps. Abbrev. :
流式细胞仪, 免疫组化-F
目录 :
317301
克隆 :
鼠单克隆抗体-CD3
产品 :
纯化抗人类CD3
抗体亚型 :
Mouse IgG2a, κ
其他名称 :
T3, CD3ε
规格 :
25微克
价格(美元) :
30美元
反应物种 :
人类
克隆性 :
单克隆
宿主 :
小鼠
共轭标签/标签/标记 :
PURE
应用注释 :
The OKT3 monoclonal antibody reacts with an epitope on the epsilon-subunit within the human CD3 complex. Clone OKT3 can block the binding of clones SK7 and UCHT1. 4 The OKT3 antibody is able to induce T cell activation. Additional reported applications (for the relevant formats) include: immunohistochemical staining of acetone-fixed frozen sections and activation of T cells. The LEAF purified antibody (Endotoxin 0.1 EU/ug, Azide-Free, 0.2 um filtered) is recommended for functional assays (Cat. No. 317304). For highly sensitive assays, we recommend Ultra-LEAF purified antibody (Cat. No. 317326) with a lower endotoxin limit than standard LEAF purified antibodies (Endotoxin 0.01 EU/ug).
更多信息或购买 :
公司信息
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品,旨在加速生命科学领域的研发工作。