产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
Alexa Fluor系列荧光染料®647抗人类FOXP3
目录 :
320214
规格 :
100试验
价格 :
370美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
AF647
克隆名称 :
259D
反应物种 :
人类
应用 :
流式细胞仪
更多信息或购买 :
文章摘录数: 23
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 人类; 图 3a
Szabo P, Dogra P, Gray J, Wells S, Connors T, Weisberg S, et al. Longitudinal profiling of respiratory and systemic immune responses reveals myeloid cell-driven lung inflammation in severe COVID-19. Immunity. 2021;54:797-814.e6 pubmed 出版商
  • 流式细胞仪; 人类; 图 s8c
Wen Z, Jin K, Shen Y, Yang Z, Li Y, Wu B, et al. N-myristoyltransferase deficiency impairs activation of kinase AMPK and promotes synovial tissue inflammation. Nat Immunol. 2019;20:313-325 pubmed 出版商
  • 流式细胞仪; 人类; 图 5a
Richardson J, Armbruster N, Günter M, Henes J, Autenrieth S. Staphylococcus aureus PSM Peptides Modulate Human Monocyte-Derived Dendritic Cells to Prime Regulatory T Cells. Front Immunol. 2018;9:2603 pubmed 出版商
Laing A, Lorenc A, Del Molino Del Barrio I, Das A, Fish M, Monin L, et al. A dynamic COVID-19 immune signature includes associations with poor prognosis. Nat Med. 2020;26:1623-1635 pubmed 出版商
Woolsey C, Jankeel A, Matassov D, Geisbert J, Agans K, Borisevich V, et al. Immune correlates of postexposure vaccine protection against Marburg virus. Sci Rep. 2020;10:3071 pubmed 出版商
Leclerc M, Voilin E, Gros G, Corgnac S, de Montpreville V, Validire P, et al. Regulation of antitumour CD8 T-cell immunity and checkpoint blockade immunotherapy by Neuropilin-1. Nat Commun. 2019;10:3345 pubmed 出版商
Burbano Y, Paz A, Caldon C, Constain J, Gonzáles G, Hernández J, et al. Low Frequency Of Regulatory B-Cells And Increased CD4+ and CD8+ Interferon-γ-producing cells in patients with tropical spastic paraparesis associated with human T-cell lymphotropic virus type. Rev Soc Bras Med Trop. 2019;52:e20190101 pubmed 出版商
Santoni de Sio F, Passerini L, Restelli S, Valente M, Pramov A, Maccari M, et al. Role of human forkhead box P3 in early thymic maturation and peripheral T-cell homeostasis. J Allergy Clin Immunol. 2018;142:1909-1921.e9 pubmed 出版商
Mackroth M, Abel A, Steeg C, Schulze zur Wiesch J, Jacobs T. Acute Malaria Induces PD1+CTLA4+ Effector T Cells with Cell-Extrinsic Suppressor Function. PLoS Pathog. 2016;12:e1005909 pubmed 出版商
Demaret J, Dupont G, Venet F, Friggeri A, Lepape A, Rimmelé T, et al. STAT5 phosphorylation in T cell subsets from septic patients in response to recombinant human interleukin-7: a pilot study. J Leukoc Biol. 2015;97:791-6 pubmed 出版商
Dupont G, Demaret J, Venet F, Malergue F, Malcus C, Poitevin Later F, et al. Comparative dose-responses of recombinant human IL-2 and IL-7 on STAT5 phosphorylation in CD4+FOXP3- cells versus regulatory T cells: a whole blood perspective. Cytokine. 2014;69:146-9 pubmed 出版商
Vudattu N, Waldron Lynch F, Truman L, Deng S, Preston Hurlburt P, Torres R, et al. Humanized mice as a model for aberrant responses in human T cell immunotherapy. J Immunol. 2014;193:587-96 pubmed 出版商
Ferraro A, D Alise A, Raj T, Asinovski N, Phillips R, Ergun A, et al. Interindividual variation in human T regulatory cells. Proc Natl Acad Sci U S A. 2014;111:E1111-20 pubmed 出版商
Chen C, Huang D, Yao S, Halliday L, Zeng G, Wang R, et al. IL-2 simultaneously expands Foxp3+ T regulatory and T effector cells and confers resistance to severe tuberculosis (TB): implicative Treg-T effector cooperation in immunity to TB. J Immunol. 2012;188:4278-88 pubmed 出版商
Presicce P, Orsborn K, King E, Pratt J, Fichtenbaum C, Chougnet C. Frequency of circulating regulatory T cells increases during chronic HIV infection and is largely controlled by highly active antiretroviral therapy. PLoS ONE. 2011;6:e28118 pubmed 出版商
Long S, Cerosaletti K, Bollyky P, Tatum M, Shilling H, Zhang S, et al. Defects in IL-2R signaling contribute to diminished maintenance of FOXP3 expression in CD4(+)CD25(+) regulatory T-cells of type 1 diabetic subjects. Diabetes. 2010;59:407-15 pubmed 出版商
Long S, Walker M, Rieck M, James E, Kwok W, Sanda S, et al. Functional islet-specific Treg can be generated from CD4+CD25- T cells of healthy and type 1 diabetic subjects. Eur J Immunol. 2009;39:612-20 pubmed 出版商
Gong G, Shao L, Wang Y, Chen C, Huang D, Yao S, et al. Phosphoantigen-activated V gamma 2V delta 2 T cells antagonize IL-2-induced CD4+CD25+Foxp3+ T regulatory cells in mycobacterial infection. Blood. 2009;113:837-45 pubmed 出版商
Long S, Buckner J. Combination of rapamycin and IL-2 increases de novo induction of human CD4(+)CD25(+)FOXP3(+) T cells. J Autoimmun. 2008;30:293-302 pubmed 出版商
Tran D, Ramsey H, Shevach E. Induction of FOXP3 expression in naive human CD4+FOXP3 T cells by T-cell receptor stimulation is transforming growth factor-beta dependent but does not confer a regulatory phenotype. Blood. 2007;110:2983-90 pubmed
Groh V, Smythe K, Dai Z, Spies T. Fas-ligand-mediated paracrine T cell regulation by the receptor NKG2D in tumor immunity. Nat Immunol. 2006;7:755-62 pubmed
Gavin M, Torgerson T, Houston E, deRoos P, Ho W, Stray Pedersen A, et al. Single-cell analysis of normal and FOXP3-mutant human T cells: FOXP3 expression without regulatory T cell development. Proc Natl Acad Sci U S A. 2006;103:6659-64 pubmed
Yang Z, Novak A, Stenson M, Witzig T, Ansell S. Intratumoral CD4+CD25+ regulatory T-cell-mediated suppression of infiltrating CD4+ T cells in B-cell non-Hodgkin lymphoma. Blood. 2006;107:3639-46 pubmed
产品信息
抗原 :
FOXP3
Apps. Abbrev. :
流式细胞仪细胞内染色
目录 :
320214
克隆 :
259D
产品 :
Alexa Fluor系列荧光染料®647抗人类FOXP3
抗体亚型 :
Mouse IgG1, κ
其他名称 :
Forkhead box protein P3, Scurfin, JM2, IPEX, Zinc finger protein JM2
规格 :
100试验
价格(美元) :
370美元
反应物种 :
人类
克隆性 :
单克隆
宿主 :
小鼠
共轭标签/标签/标记 :
A647
免疫原 :
全长FOXP3蛋白
应用注释 :
Additional reported applications (for the relevant formats) include: Western blotting 1 , and immunohistochemical staining 1 of acetone-fixed frozen sections and formalin-fixed paraffin-embedded sections. The 259D antibody gives strong positivity on paraffin and frozen sections and the antibody stains some epithelial cells. The binding of 206D to FOXP3 can be partially blocked by 259D, but 206D does not show significant blocking effect on 259D binding. NOTE : For flow cytometric staining with this clone, True-Nuclear Transcription Factor Buffer Set (Cat. No. 424401 ) offers improved staining and is highly recommended.
更多信息或购买 :
公司信息
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品,旨在加速生命科学领域的研发工作。