产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
纯化抗人类IL-4
目录 :
500802
规格 :
500微克
价格 :
136美元
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
MP4-25D2
反应物种 :
人类, 小鼠
应用 :
酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 中和反应, 流式细胞仪, dot blot, 抑制或激活实验, mass cytometry
更多信息或购买 :
文章摘录数: 26
出版应用/物种/样本/稀释参考文献
  • mass cytometry; 人类; 图 s1a
Ingelfinger F, Krishnarajah S, Kramer M, Utz S, Galli E, Lutz M, et al. Single-cell profiling of myasthenia gravis identifies a pathogenic T cell signature. Acta Neuropathol. 2021;141:901-915 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5a
Gowthaman U, Chen J, Zhang B, Flynn W, Lu Y, Song W, et al. Identification of a T follicular helper cell subset that drives anaphylactic IgE. Science. 2019;365: pubmed 出版商
  • 流式细胞仪; 人类; 表 1
Sumatoh H, Teng K, Cheng Y, Newell E. Optimization of mass cytometry sample cryopreservation after staining. Cytometry A. 2017;91:48-61 pubmed 出版商
  • 抑制或激活实验; 人类
Kobayashi S, Watanabe T, Suzuki R, Furu M, Ito H, Ito J, et al. TGF-β induces the differentiation of human CXCL13-producing CD4(+) T cells. Eur J Immunol. 2016;46:360-71 pubmed 出版商
  • dot blot; 人类; 表 s1
Lu Y, Xue Q, Eisele M, Sulistijo E, Brower K, Han L, et al. Highly multiplexed profiling of single-cell effector functions reveals deep functional heterogeneity in response to pathogenic ligands. Proc Natl Acad Sci U S A. 2015;112:E607-15 pubmed 出版商
  • 免疫细胞化学; 人类
Yu C, Becker C, Metang P, Marches F, Wang Y, Toshiyuki H, et al. Human CD141+ dendritic cells induce CD4+ T cells to produce type 2 cytokines. J Immunol. 2014;193:4335-43 pubmed 出版商
  • 流式细胞仪; 人类
Weist B, Schmueck M, Fuehrer H, Sattler A, Reinke P, Babel N. The role of CD4(+) T cells in BKV-specific T cell immunity. Med Microbiol Immunol. 2014;203:395-408 pubmed 出版商
Singh A, Kazer S, Roider J, Krista K, Millar J, Asowata O, et al. Innate Lymphoid Cell Activation and Sustained Depletion in Blood and Tissue of Children Infected with HIV from Birth Despite Antiretroviral Therapy. Cell Rep. 2020;32:108153 pubmed 出版商
Katsuyama E, Suárez Fueyo A, Bradley S, Mizui M, Marin A, Mulki L, et al. The CD38/NAD/SIRTUIN1/EZH2 Axis Mitigates Cytotoxic CD8 T Cell Function and Identifies Patients with SLE Prone to Infections. Cell Rep. 2020;30:112-123.e4 pubmed 出版商
van de Garde M, van Westen E, Poelen M, Rots N, van Els C. Prediction and Validation of Immunogenic Domains of Pneumococcal Proteins Recognized by Human CD4+ T Cells. Infect Immun. 2019;87: pubmed 出版商
Logtenberg M, Jansen J, Raaben M, Toebes M, Franke K, Brandsma A, et al. Glutaminyl cyclase is an enzymatic modifier of the CD47- SIRPα axis and a target for cancer immunotherapy. Nat Med. 2019;25:612-619 pubmed 出版商
Schlenner S, Pasciuto E, Lagou V, Burton O, Prezzemolo T, Junius S, et al. NFIL3 mutations alter immune homeostasis and sensitise for arthritis pathology. Ann Rheum Dis. 2019;78:342-349 pubmed 出版商
Yugo D, Heffron C, Ryu J, Uh K, Subramaniam S, Matzinger S, et al. Infection Dynamics of Hepatitis E Virus in Wild-Type and Immunoglobulin Heavy Chain Knockout JH -/- Gnotobiotic Piglets. J Virol. 2018;92: pubmed 出版商
Ma F, Zhang Y, Xing J, Song X, Huang L, Weng H, et al. Fecal bacteria from treatment-naive Crohn's disease patients can skew helper T cell responses. Exp Cell Res. 2017;361:135-140 pubmed 出版商
Na H, Lim H, Choi G, Kim B, Kim S, Chang Y, et al. Concomitant suppression of TH2 and TH17 cell responses in allergic asthma by targeting retinoic acid receptor-related orphan receptor ?t. J Allergy Clin Immunol. 2018;141:2061-2073.e5 pubmed 出版商
Das A, Rouault Pierre K, Kamdar S, Gomez Tourino I, Wood K, Donaldson I, et al. Adaptive from Innate: Human IFN-γ+CD4+ T Cells Can Arise Directly from CXCL8-Producing Recent Thymic Emigrants in Babies and Adults. J Immunol. 2017;199:1696-1705 pubmed 出版商
Mou W, Han W, Ma X, Wang X, Qin H, Zhao W, et al. γδTFH cells promote B cell maturation and antibody production in neuroblastoma. BMC Immunol. 2017;18:36 pubmed 出版商
Sulzer D, Alcalay R, Garretti F, Cote L, Kanter E, Agin Liebes J, et al. T cells from patients with Parkinson's disease recognize α-synuclein peptides. Nature. 2017;546:656-661 pubmed 出版商
Cao D, Cao Q, Subramaniam S, Yugo D, Heffron C, Rogers A, et al. Pig model mimicking chronic hepatitis E virus infection in immunocompromised patients to assess immune correlates during chronicity. Proc Natl Acad Sci U S A. 2017;114:6914-6923 pubmed 出版商
Buranapraditkun S, Pissani F, Teigler J, Schultz B, Alter G, Marovich M, et al. Preservation of Peripheral T Follicular Helper Cell Function in HIV Controllers. J Virol. 2017;91: pubmed 出版商
Jiang J, Liu C, Liu M, Shen Y, Hu X, Wang Q, et al. OX40 signaling is involved in the autoactivation of CD4+CD28- T cells and contributes to the pathogenesis of autoimmune arthritis. Arthritis Res Ther. 2017;19:67 pubmed 出版商
Aravena O, Ferrier A, Menon M, Mauri C, Aguillon J, Soto L, et al. TIM-1 defines a human regulatory B cell population that is altered in frequency and function in systemic sclerosis patients. Arthritis Res Ther. 2017;19:8 pubmed 出版商
Kroenke M, Eto D, Locci M, Cho M, Davidson T, Haddad E, et al. Bcl6 and Maf cooperate to instruct human follicular helper CD4 T cell differentiation. J Immunol. 2012;188:3734-44 pubmed 出版商
Lee J, Ulrich B, Cho J, Park J, Kim C. Progesterone promotes differentiation of human cord blood fetal T cells into T regulatory cells but suppresses their differentiation into Th17 cells. J Immunol. 2011;187:1778-87 pubmed 出版商
Iwamoto S, Iwai S, Tsujiyama K, Kurahashi C, Takeshita K, Naoe M, et al. TNF-alpha drives human CD14+ monocytes to differentiate into CD70+ dendritic cells evoking Th1 and Th17 responses. J Immunol. 2007;179:1449-57 pubmed
Dzhagalov I, Chambon P, He Y. Regulation of CD8+ T lymphocyte effector function and macrophage inflammatory cytokine production by retinoic acid receptor gamma. J Immunol. 2007;178:2113-21 pubmed
产品信息
抗原 :
IL-4
Apps. Abbrev. :
ELISA, CyTOF®, Neut, Intracellular Staining for Flow Cytometry, IHC
目录 :
500802
克隆 :
MP4-25D2
产品 :
纯化抗人类IL-4
抗体亚型 :
Rat IgG1, κ
其他名称 :
Interleukin-4, Ia inducing factor (IaIF), B-cell stimulating factor-1 (BSF-1), Hodgkin's cell growth factor (HCGF), Mast cell growth factor-2 (MCGF-2), Macrophage fusion factor (MFF), T cell growth factor-2 (TCGF-2)
规格 :
500微克
价格(美元) :
136美元
反应物种 :
人类
克隆性 :
单克隆
宿主 :
大鼠
共轭标签/标签/标记 :
PURE
免疫原 :
CHO-expressed, recombinant human IL-4
应用注释 :
ELISA Detection 1,3 or ELISPOT Detection 4,5 : The biotinylated MP4-25D2 antibody is useful as a detection antibody for a sandwich ELISA or ELISPOT assay, when used in conjunction with purified 8D4-8 antibody (Cat. No. 500702/500707) as the capture antibody. Flow Cytometry 6,9 : The fluorochrome-labeled MP4-25D2 antibody is useful for intracellular immunofluorescent staining and flow cytometric analysis to identify IL-4 -producing cells within mixed cell populations. Neutralization 1-3 : The LEAF purified antibody (Endotoxin 0.1 EU/ug, Azide-Free, 0.2 um filtered) is recommended for neutralization of human IL-4 bioactivity (Cat. No. 500815). The MP4-25D2 antibody can neutralize the bioactivity of natural or recombinant IL-4.
更多信息或购买 :
公司信息
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品,旨在加速生命科学领域的研发工作。