产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
Purified anti-human TNF-α (Maxpar® Ready)
目录 :
502941
规格 :
100微克
价格 :
120美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
MAb11
反应物种 :
African green monkey, 人类, , 猕猴
应用 :
酶联免疫吸附测定, 免疫细胞化学, 流式细胞仪
更多信息或购买 :
文章摘录数: 19
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 人类; 图 8d
Aulicino A, Rue Albrecht K, Preciado Llanes L, Napolitani G, Ashley N, Cribbs A, et al. Invasive Salmonella exploits divergent immune evasion strategies in infected and bystander dendritic cell subsets. Nat Commun. 2018;9:4883 pubmed 出版商
  • 流式细胞仪; 人类; 图 2h
Pizzolla A, Nguyen T, Sant S, Jaffar J, Loudovaris T, Mannering S, et al. Influenza-specific lung-resident memory T cells are proliferative and polyfunctional and maintain diverse TCR profiles. J Clin Invest. 2018;128:721-733 pubmed 出版商
  • 流式细胞仪; 猕猴
Roberts E, Carnathan D, Li H, Shaw G, Silvestri G, Betts M. Collapse of Cytolytic Potential in SIV-Specific CD8+ T Cells Following Acute SIV Infection in Rhesus Macaques. PLoS Pathog. 2016;12:e1006135 pubmed 出版商
  • 流式细胞仪; 人类; 图 s1e
Cheng W, van Asten S, Burns L, Evans H, Walter G, Hashim A, et al. Periodontitis-associated pathogens P. gingivalis and A. actinomycetemcomitans activate human CD14(+) monocytes leading to enhanced Th17/IL-17 responses. Eur J Immunol. 2016;46:2211-21 pubmed 出版商
  • 流式细胞仪; 人类; 图 6a
Gadd V, Patel P, Jose S, Horsfall L, Powell E, Irvine K. Altered Peripheral Blood Monocyte Phenotype and Function in Chronic Liver Disease: Implications for Hepatic Recruitment and Systemic Inflammation. PLoS ONE. 2016;11:e0157771 pubmed 出版商
  • 流式细胞仪; African green monkey; 图 1b
Neumann B, Shi T, Gan L, Klippert A, Daskalaki M, Stolte Leeb N, et al. Comprehensive panel of cross-reacting monoclonal antibodies for analysis of different immune cells and their distribution in the common marmoset (Callithrix jacchus). J Med Primatol. 2016;45:139-46 pubmed 出版商
  • 流式细胞仪; 猪; 图 7d
Bähr A, Käser T, Kemter E, Gerner W, Kurome M, Baars W, et al. Ubiquitous LEA29Y Expression Blocks T Cell Co-Stimulation but Permits Sexual Reproduction in Genetically Modified Pigs. PLoS ONE. 2016;11:e0155676 pubmed 出版商
  • 流式细胞仪; 人类; 图 1
Lee Chang C, Bodogai M, Moritoh K, Chen X, Wersto R, Sen R, et al. Aging Converts Innate B1a Cells into Potent CD8+ T Cell Inducers. J Immunol. 2016;196:3385-97 pubmed 出版商
  • 流式细胞仪; 人类; 图 4b
Vallera D, Felices M, McElmurry R, McCullar V, Zhou X, Schmohl J, et al. IL15 Trispecific Killer Engagers (TriKE) Make Natural Killer Cells Specific to CD33+ Targets While Also Inducing Persistence, In Vivo Expansion, and Enhanced Function. Clin Cancer Res. 2016;22:3440-50 pubmed 出版商
  • 流式细胞仪; 人类; 图 1
Yawata N, Selva K, Liu Y, Tan K, Lee A, Siak J, et al. Dynamic change in natural killer cell type in the human ocular mucosa in situ as means of immune evasion by adenovirus infection. Mucosal Immunol. 2016;9:159-70 pubmed 出版商
  • 免疫细胞化学; 人类; 图 6
Schnorfeil F, Lichtenegger F, Emmerig K, Schlueter M, Neitz J, Draenert R, et al. T cells are functionally not impaired in AML: increased PD-1 expression is only seen at time of relapse and correlates with a shift towards the memory T cell compartment. J Hematol Oncol. 2015;8:93 pubmed 出版商
  • 流式细胞仪; 猪
Talker S, Koinig H, Stadler M, Graage R, Klingler E, Ladinig A, et al. Magnitude and kinetics of multifunctional CD4+ and CD8β+ T cells in pigs infected with swine influenza A virus. Vet Res. 2015;46:52 pubmed 出版商
  • 流式细胞仪; 人类; 图 1
Boyle M, Jagannathan P, Bowen K, McIntyre T, Vance H, Farrington L, et al. Effector Phenotype of Plasmodium falciparum-Specific CD4+ T Cells Is Influenced by Both Age and Transmission Intensity in Naturally Exposed Populations. J Infect Dis. 2015;212:416-25 pubmed 出版商
  • 流式细胞仪; 猪
Gerner W, Talker S, Koinig H, Sedlak C, Mair K, Saalmüller A. Phenotypic and functional differentiation of porcine αβ T cells: current knowledge and available tools. Mol Immunol. 2015;66:3-13 pubmed 出版商
  • 流式细胞仪; 人类
Sueur C, Lupo J, Mas P, Morand P, Boyer V. Difference in cytokine production and cell cycle progression induced by Epstein-Barr virus Lmp1 deletion variants in Kmh2, a Hodgkin lymphoma cell line. Virol J. 2014;11:94 pubmed 出版商
  • 流式细胞仪; 人类; 图 3a
Duggal N, Beswetherick A, Upton J, Hampson P, Phillips A, Lord J. Depressive symptoms in hip fracture patients are associated with reduced monocyte superoxide production. Exp Gerontol. 2014;54:27-34 pubmed 出版商
  • 流式细胞仪; 人类; 表 2
Krishnan S, Wilson E, Sheikh V, Rupert A, Mendoza D, Yang J, et al. Evidence for innate immune system activation in HIV type 1-infected elite controllers. J Infect Dis. 2014;209:931-9 pubmed 出版商
  • 流式细胞仪; 人类
Marin N, Paris S, Rojas M, Garcia L. Functional profile of CD4+ and CD8+ T cells in latently infected individuals and patients with active TB. Tuberculosis (Edinb). 2013;93:155-66 pubmed 出版商
Iwamoto S, Iwai S, Tsujiyama K, Kurahashi C, Takeshita K, Naoe M, et al. TNF-alpha drives human CD14+ monocytes to differentiate into CD70+ dendritic cells evoking Th1 and Th17 responses. J Immunol. 2007;179:1449-57 pubmed
产品信息
抗原 :
肿瘤坏死因子-a
Apps. Abbrev. :
酶联免疫吸附测定, CyTOF®
目录 :
502941
克隆 :
MAb11
产品 :
Purified anti-human TNF-α (Maxpar® Ready)
抗体亚型 :
Mouse IgG1, κ
其他名称 :
Tumor necrosis factor-α, Cachectin, Necrosin, Macrophage cytotoxic factor (MCF), Differentiation inducing factor (DIF), TNFSF2
规格 :
100微克
价格(美元) :
120美元
反应物种 :
Human, Cat (Feline), Cross-Reactivity: Chimpanzee, Baboon, Cynomolgus, Rhesus, Swine (Pig, Porcine), Pigtailed Macaque, Sooty Mangabey
克隆性 :
单克隆
宿主 :
小鼠
共轭标签/标签/标记 :
PUREMAX
免疫原 :
E. coli -expressed, recombinant human TNF-α
应用注释 :
ELISA or ELISPOT Detection: The biotinylated MAb11 antibody is useful as the detection antibody in a sandwich ELISA or ELISPOT, when used in conjunction with the purified MAb1 antibody (Cat. No. 502802/502804) as the capture antibody. Flow Cytometry 3,5,6,10 : The fluorochrome-labeled MAb11 antibody is useful for intracellular and membrane-bound immunofluorescent staining and flow cytometric analysis to identify TNF- -producing cells within mixed cell populations. Additional reported applications (for the relevant formats) include: neutralization 1,2 , immunohistochemical staining of paraformaldehyde-fixed, saponin-treated frozen tissue sections 4 and acetone-fixed frozen tissue sections 8 , immunocytochemistry 7 , and immunofluorescence 9 . The MAb11 antibody can neutralize the bioactivity of natural or recombinant TNF- . Note: For testing human TNF- in serum or plasma, BioLegend s ELISA Max™ Sets (Cat. No. 430201 to 430206) are specially developed and recommended. The LEAF™ purified antibody (Endotoxin 0.1 EU/ug, Azide-Free, 0.2 µm filtered) is recommended for neutralization of human TNF- bioactivity (Cat. No. 502922). The Purified MAb1 antibody is useful in neutralization 2 and as the capture antibody in a sandwich ELISA or ELISPOT assay, when used in conjunction with the biotinylated MAb11 antibody (Cat. No. 502904/502914) as the detecting antibody.
更多信息或购买 :
公司信息
BioLegend
9727 Pacific Heights Blvd.
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品,旨在加速生命科学领域的研发工作。