产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
Purified anti-mouse IL-6 (Maxpar® Ready)
目录 :
504509
规格 :
100微克
价格 :
141美元
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
MP5-20F3
反应物种 :
小鼠
应用 :
酶联免疫吸附测定, 流式细胞仪, 抑制或激活实验
更多信息或购买 :
BioLegend 产品网页
文章摘录数: 18
出版应用/物种/样本/稀释参考文献
  • 流式细胞仪; 小鼠; 图 4c, 4d
Meryk A, Grasse M, Balasco L, Kapferer W, Grubeck Loebenstein B, Pangrazzi L. Antioxidants N-Acetylcysteine and Vitamin C Improve T Cell Commitment to Memory and Long-Term Maintenance of Immunological Memory in Old Mice. Antioxidants (Basel). 2020;9: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 2d
Forbester J, Clement M, Wellington D, Yeung A, Dimonte S, Marsden M, et al. IRF5 Promotes Influenza Virus-Induced Inflammatory Responses in Human Induced Pluripotent Stem Cell-Derived Myeloid Cells and Murine Models. J Virol. 2020;94: pubmed 出版商
  • 流式细胞仪; 小鼠; 图 4c
Stacey M, Clare S, Clement M, Marsden M, Abdul Karim J, Kane L, et al. The antiviral restriction factor IFN-induced transmembrane protein 3 prevents cytokine-driven CMV pathogenesis. J Clin Invest. 2017;127:1463-1474 pubmed 出版商
  • 流式细胞仪; 小鼠; 1:100; 图 7A
Li C, Bi Y, Li Y, Yang H, Yu Q, Wang J, et al. Dendritic cell MST1 inhibits Th17 differentiation. Nat Commun. 2017;8:14275 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 5
Lasigliè D, Boero S, Bauer I, Morando S, Damonte P, Cea M, et al. Sirt6 regulates dendritic cell differentiation, maturation, and function. Aging (Albany NY). 2016;8:34-49 pubmed
  • 酶联免疫吸附测定; 小鼠; 图 5
Lee J, Park K, Han D, Bang N, Kim D, Na H, et al. PharmDB-K: Integrated Bio-Pharmacological Network Database for Traditional Korean Medicine. PLoS ONE. 2015;10:e0142624 pubmed 出版商
  • 抑制或激活实验; 小鼠; 50 ug/mice
Chuang H, Sheu W, Lin Y, Tsai C, Yang C, Cheng Y, et al. HGK/MAP4K4 deficiency induces TRAF2 stabilization and Th17 differentiation leading to insulin resistance. Nat Commun. 2014;5:4602 pubmed 出版商
Gruber C, Patel R, Trachtman R, Lepow L, Amanat F, Krammer F, et al. Mapping Systemic Inflammation and Antibody Responses in Multisystem Inflammatory Syndrome in Children (MIS-C). Cell. 2020;183:982-995.e14 pubmed 出版商
Stras S, Werner L, Toothaker J, Olaloye O, Oldham A, McCourt C, et al. Maturation of the Human Intestinal Immune System Occurs Early in Fetal Development. Dev Cell. 2019;51:357-373.e5 pubmed 出版商
Malara A, Gruppi C, Abbonante V, Cattaneo D, De Marco L, Massa M, et al. EDA fibronectin-TLR4 axis sustains megakaryocyte expansion and inflammation in bone marrow fibrosis. J Exp Med. 2019;216:587-604 pubmed 出版商
Tanaka S, Suto A, Iwamoto T, Kageyama T, Tamachi T, Takatori H, et al. Sox12 promotes T reg differentiation in the periphery during colitis. J Exp Med. 2018;215:2509-2519 pubmed 出版商
St Leger A, Hansen A, Karauzum H, Horai R, Yu C, Laurence A, et al. STAT-3-independent production of IL-17 by mouse innate-like αβ T cells controls ocular infection. J Exp Med. 2018;215:1079-1090 pubmed 出版商
Meier L, Auger J, Engelson B, Cowan H, Breed E, Gonzalez Torres M, et al. CD301b/MGL2+ Mononuclear Phagocytes Orchestrate Autoimmune Cardiac Valve Inflammation and Fibrosis. Circulation. 2018;137:2478-2493 pubmed 出版商
Li B, Wang X, Choi I, Wang Y, Liu S, Pham A, et al. miR-146a modulates autoreactive Th17 cell differentiation and regulates organ-specific autoimmunity. J Clin Invest. 2017;127:3702-3716 pubmed 出版商
Peterson L, Philip N, DeLaney A, Wynosky Dolfi M, Asklof K, Gray F, et al. RIPK1-dependent apoptosis bypasses pathogen blockade of innate signaling to promote immune defense. J Exp Med. 2017;214:3171-3182 pubmed 出版商
Burbage M, Keppler S, Montaner B, Mattila P, Batista F. The Small Rho GTPase TC10 Modulates B Cell Immune Responses. J Immunol. 2017;199:1682-1695 pubmed 出版商
Ohlund D, Handly Santana A, Biffi G, Elyada E, Almeida A, Ponz Sarvisé M, et al. Distinct populations of inflammatory fibroblasts and myofibroblasts in pancreatic cancer. J Exp Med. 2017;214:579-596 pubmed 出版商
Ozeki Y, Sugawara I, Udagawa T, Aoki T, Osada Oka M, Tateishi Y, et al. Transient role of CD4+CD25+ regulatory T cells in mycobacterial infection in mice. Int Immunol. 2010;22:179-89 pubmed 出版商
产品信息
抗原 :
IL-6
Apps. Abbrev. :
ELISA捕获, CyTOF®
目录 :
504509
克隆 :
MP5-20F3
产品 :
Purified anti-mouse IL-6 (Maxpar® Ready)
抗体亚型 :
Rat IgG1, κ
其他名称 :
Interleukin-6, B cell stimulating factor-2 (BSF-2), Cytotoxic T cell differentiation factor (CDF), Hepatocyte stimulating factor (HSF), Hybridoma/plasmacytoma growth factor (HPGF)
规格 :
100微克
价格(美元) :
141美元
反应物种 :
小鼠
克隆性 :
单克隆
宿主 :
大鼠
共轭标签/标签/标记 :
PUREMAX
免疫原 :
COS-7-expressed, 重组小鼠IL-6
应用注释 :
ELISA Capture 1-3,11 or ELISPOT Capture 4,5 : The purified MP5-20F3 antibody is useful as the capture antibody in a sandwich ELISA or ELISPOT assay, when used in conjunction with the biotinylated MP5-32C11 antibody (Cat. No. 504602) as the detecting antibody and recombinant mouse IL-6 (Cat. No. 575709) as the standard. The Ultra-LEAF purified antibody is suggested for ELISPOT capture. Flow Cytometry: The fluorochrome-labeled MP5-20F3 antibody is useful for intracellular immunofluorescent staining and flow cytometric analysis to identify IL-6 -producing cells within mixed cell populations. For intracellular cytokine staining protocol, please visit www.biolegend.com and click on the support section. Neutralization 1-2,8-10 : The Ultra-LEAF purified antibody (Endotoxin 0.1 EU/ug, Azide-Free, 0.2 um filtered) is recommended for neutralization of mouse IL-6 bioactivity in vivo and in vitro (Cat. No. 504506). Additional reported applications (for relevant formats of this clone) include: In Vivo Capture 7 , and immunohistochemical staining (paraformaldehyde-fixed/saponin-treated 6 , and acetone-fixed frozen tissue sections 13, 14 ). Note: For testing mouse IL-6 in serum, plasma or supernatant, BioLegend s ELISA Max Sets (Cat. No. 431301 to 431306) are specially developed and recommended.
更多信息或购买 :
BioLegend 产品网页
公司信息
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品，旨在加速生命科学领域的研发工作。