产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
Ultra-LEAF™ Purified anti-mouse IL-12/IL-23 p40
目录 :
505307
规格 :
100微克
价格 :
100美元
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
C17.8
反应物种 :
小鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 中和反应, 免疫沉淀, 抑制或激活实验
更多信息或购买 :
文章摘录数: 7
出版应用/物种/样本/稀释参考文献
  • 抑制或激活实验; 小鼠; 10 ug/ml
Contreras F, Prado C, Gonzalez H, Franz D, Osorio Barrios F, Osorio F, et al. Dopamine Receptor D3 Signaling on CD4+ T Cells Favors Th1- and Th17-Mediated Immunity. J Immunol. 2016;196:4143-9 pubmed 出版商
  • 酶联免疫吸附测定; 小鼠; 图 6
Li J, Liu D, Mou Z, Ihedioha O, Blanchard A, Jia P, et al. Deficiency of prolactin-inducible protein leads to impaired Th1 immune response and susceptibility to Leishmania major in mice. Eur J Immunol. 2015;45:1082-91 pubmed 出版商
  • 抑制或激活实验; 小鼠; 10 ug/ml
Koga T, Hedrich C, Mizui M, Yoshida N, Otomo K, Lieberman L, et al. CaMK4-dependent activation of AKT/mTOR and CREM-? underlies autoimmunity-associated Th17 imbalance. J Clin Invest. 2014;124:2234-45 pubmed 出版商
Imanishi T, Unno M, Kobayashi W, Yoneda N, Akira S, Saito T. mTORC1 Signaling Controls TLR2-Mediated T-Cell Activation by Inducing TIRAP Expression. Cell Rep. 2020;32:107911 pubmed 出版商
Price C, Jones S, Mihelcic M, Santic M, Abu Kwaik Y. Paradoxical Pro-inflammatory Responses by Human Macrophages to an Amoebae Host-Adapted Legionella Effector. Cell Host Microbe. 2020;27:571-584.e7 pubmed 出版商
Xu G, Liu D, Fan Y, Yang X, Korner H, Fu Y, et al. Lymphotoxin alpha beta 2 (membrane lymphotoxin) is critically important for resistance to Leishmania major infection in mice. J Immunol. 2007;179:5358-66 pubmed
Sugimoto K, Ogawa A, Shimomura Y, Nagahama K, Mizoguchi A, Bhan A. Inducible IL-12-producing B cells regulate Th2-mediated intestinal inflammation. Gastroenterology. 2007;133:124-36 pubmed
产品信息
抗原 :
IL-12 IL-23
Apps. Abbrev. :
ELISA, Neut, Intracellular Staining for Flow Cytometry, IP, Western Blotting
目录 :
505307
克隆 :
C17.8
产品 :
Ultra-LEAF™ Purified anti-mouse IL-12/IL-23 p40
抗体亚型 :
Rat IgG2a, κ
其他名称 :
Interleukin-12 p40, Interleukin-23 p40, Cytotoxic lymphocyte maturation factor (CLMF), Natural killer cell stimulatory factor (NKSF), CTL maturation factor (TcMF), T-cell stimulating factor (TSF)
规格 :
100微克
价格(美元) :
100美元
反应物种 :
Mouse, IL-12/IL-23 p40 subunit (monomer, homodimer and heterodimer IL-12 p35/p40 or IL-23 p19/p40)
克隆性 :
单克隆
宿主 :
大鼠
共轭标签/标签/标记 :
ULEAF
免疫原 :
CHO expressed, recombinant mouse IL-12 p70
应用注释 :
ELISA Detection 1,2,6-9 or ELISPOT Detection: The biotinylated C17.8 antibody is useful as a detection antibody for a sandwich ELISA or ELISPOT assay, when used in conjunction with the purified C15.6 antibody (Cat. No. 505202/505208) as capture antibody and recombinant mouse IL-12/IL-23 p40 (Cat. No. 576909) or recombinant mouse IL-12 p70 (Cat. No. 577009) as the standard. Neutralization 1,2,4,5,6,10 : The LEAF™ purified antibody (Endotoxin 0.1 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for neutralization of mouse IL-12 bioactivity in vivo and in vitro (Cat. No. 505304). For in vivo studies or highly sensitive assays, we recommend Ultra-LEAF™ purified antibody (Cat. No. 505308) with a lower endotoxin limit than standard LEAF™ purified antibodies (Endotoxin 0.01 EU/µg). Additional reported applications (for relevant formats of this clone) include: Western blotting 3 , immunoprecipitation 3 , and intracellular immunofluorescent staining and flow cytometric analysis. Note: For testing mouse IL-12 p40 (monomer, dimer, heterodimer) in serum or plasma, BioLegend s ELISA Max™ Sets (Cat. No. 431601 to 431606) are specially developed and recommended.
更多信息或购买 :
公司信息
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品,旨在加速生命科学领域的研发工作。