产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
纯化抗小鼠IFN-γ
目录 :
505702
规格 :
500微克
价格 :
115美元
克隆性 :
单克隆
宿主 :
大鼠
共轭标签 :
未共轭
克隆名称 :
R4-6A2
反应物种 :
小鼠
应用 :
酶联免疫吸附测定, 免疫组化, 流式细胞仪, 抑制或激活实验
更多信息或购买 :
文章摘录数: 28
出版应用/物种/样本/稀释参考文献
  • 酶联免疫吸附测定; 小鼠; 图 2e
Strandt H, Pinheiro D, Kaplan D, Wirth D, GRATZ I, Hammerl P, et al. Neoantigen Expression in Steady-State Langerhans Cells Induces CTL Tolerance. J Immunol. 2017;199:1626-1634 pubmed 出版商
  • 流式细胞仪; 小鼠; 图 1c
Singh R, Miao T, Symonds A, Omodho B, Li S, Wang P. Egr2 and 3 Inhibit T-bet-Mediated IFN-? Production in T Cells. J Immunol. 2017;198:4394-4402 pubmed 出版商
  • 抑制或激活实验; 小鼠; 图 s4c
Angela M, Endo Y, Asou H, Yamamoto T, Tumes D, Tokuyama H, et al. Fatty acid metabolic reprogramming via mTOR-mediated inductions of PPAR? directs early activation of T cells. Nat Commun. 2016;7:13683 pubmed 出版商
Volpedo G, Pacheco Fernández T, Holcomb E, Zhang W, Lypaczewski P, Cox B, et al. Centrin-deficient Leishmania mexicana confers protection against New World cutaneous leishmaniasis. NPJ Vaccines. 2022;7:32 pubmed 出版商
Chen Y, Liu R, Cui Y, Hettinghouse A, Fu W, Zhang L, et al. Penfluridol targets acid sphingomyelinase to inhibit TNF signaling and is therapeutic against inflammatory autoimmune diseases. Arthritis Res Ther. 2022;24:27 pubmed 出版商
McCauley M, O Rourke J, Yáñez A, Markman J, Ho R, Wang X, et al. C9orf72 in myeloid cells suppresses STING-induced inflammation. Nature. 2020;585:96-101 pubmed 出版商
Wu J, Weisshaar N, Hotz Wagenblatt A, Madi A, Ma S, Mieg A, et al. Skeletal muscle antagonizes antiviral CD8+ T cell exhaustion. Sci Adv. 2020;6:eaba3458 pubmed 出版商
Lv Z, Zhang P, Li D, Qin M, Nie L, Wang X, et al. CD19-targeting fusion protein combined with PD1 antibody enhances anti-tumor immunity in mouse models. Oncoimmunology. 2020;9:1747688 pubmed 出版商
Baumann D, Hägele T, Mochayedi J, Drebant J, Vent C, Blobner S, et al. Proimmunogenic impact of MEK inhibition synergizes with agonist anti-CD40 immunostimulatory antibodies in tumor therapy. Nat Commun. 2020;11:2176 pubmed 出版商
Mohamed E, Sierra R, Trillo Tinoco J, Cao Y, Innamarato P, Payne K, et al. The Unfolded Protein Response Mediator PERK Governs Myeloid Cell-Driven Immunosuppression in Tumors through Inhibition of STING Signaling. Immunity. 2020;52:668-682.e7 pubmed 出版商
Steinmann S, Schoedsack M, Heinrich F, Breda P, Ochel A, Tiegs G, et al. Hepatic ILC2 activity is regulated by liver inflammation-induced cytokines and effector CD4+ T cells. Sci Rep. 2020;10:1071 pubmed 出版商
Zander R, SCHAUDER D, Xin G, Nguyen C, Wu X, ZAJAC A, et al. CD4+ T Cell Help Is Required for the Formation of a Cytolytic CD8+ T Cell Subset that Protects against Chronic Infection and Cancer. Immunity. 2019;51:1028-1042.e4 pubmed 出版商
Harel M, Ortenberg R, Varanasi S, Mangalhara K, Mardamshina M, Markovits E, et al. Proteomics of Melanoma Response to Immunotherapy Reveals Mitochondrial Dependence. Cell. 2019;179:236-250.e18 pubmed 出版商
Rauschenberger T, Schmitt V, Azeem M, Klein Hessling S, Murti K, Grän F, et al. T Cells Control Chemokine Secretion by Keratinocytes. Front Immunol. 2019;10:1917 pubmed 出版商
Fulham M, Ratna A, Gerstein R, Kurt Jones E, Mandrekar P. Alcohol-induced adipose tissue macrophage phenotypic switching is independent of myeloid Toll-like receptor 4 expression. Am J Physiol Cell Physiol. 2019;317:C687-C700 pubmed 出版商
Komuczki J, Tuzlak S, Friebel E, Hartwig T, Spath S, Rosenstiel P, et al. Fate-Mapping of GM-CSF Expression Identifies a Discrete Subset of Inflammation-Driving T Helper Cells Regulated by Cytokines IL-23 and IL-1β. Immunity. 2019;: pubmed 出版商
Mastroianni J, Stickel N, Andrlova H, Hanke K, Melchinger W, Duquesne S, et al. miR-146a Controls Immune Response in the Melanoma Microenvironment. Cancer Res. 2019;79:183-195 pubmed 出版商
Simula L, Pacella I, Colamatteo A, Procaccini C, Cancila V, Bordi M, et al. Drp1 Controls Effective T Cell Immune-Surveillance by Regulating T Cell Migration, Proliferation, and cMyc-Dependent Metabolic Reprogramming. Cell Rep. 2018;25:3059-3073.e10 pubmed 出版商
Deason K, Troutman T, Jain A, Challa D, Mandraju R, Brewer T, et al. BCAP links IL-1R to the PI3K-mTOR pathway and regulates pathogenic Th17 cell differentiation. J Exp Med. 2018;215:2413-2428 pubmed 出版商
Godoy Calderón M, Salazar V, González Marcano E, Convit A. Autologous tumor cells/bacillus Calmette-Guérin/formalin-based novel breast cancer vaccine induces an immune antitumor response. Oncotarget. 2018;9:20222-20238 pubmed 出版商
Meyer zu Horste G, Przybylski D, Schramm M, Wang C, Schnell A, Lee Y, et al. Fas Promotes T Helper 17 Cell Differentiation and Inhibits T Helper 1 Cell Development by Binding and Sequestering Transcription Factor STAT1. Immunity. 2018;48:556-569.e7 pubmed 出版商
Vaartjes D, Nandakumar K, Holmdahl R, Raposo B. Increased salt exposure affects both lymphoid and myeloid effector functions, influencing innate-associated disease but not T-cell-associated autoimmunity. Immunology. 2018;: pubmed 出版商
Liang D, Tian L, You R, Halpert M, Konduri V, Baig Y, et al. AIMp1 Potentiates TH1 Polarization and Is Critical for Effective Antitumor and Antiviral Immunity. Front Immunol. 2017;8:1801 pubmed 出版商
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产品信息
抗原 :
IFN丙
Apps. Abbrev. :
ELISA捕获, 免疫组化
目录 :
505702
克隆 :
R4-6A2
产品 :
纯化抗小鼠IFN-γ
抗体亚型 :
Rat IgG1, κ
其他名称 :
Interferon-γ, Immune interferon, Type II interferon, T cell interferon, Macrophage-activating factor (MAF), IFN-g, IFN-gamma
规格 :
500微克
价格(美元) :
115美元
反应物种 :
小鼠
克隆性 :
单克隆
宿主 :
大鼠
共轭标签/标签/标记 :
PURE
免疫原 :
Partially-purified, native mouse IFN-γ
应用注释 :
ELISA Capture 1-4,6,10,11 or ELISPOT Capture 5 : The purified R4-6A2 antibody is useful as the capture antibody in a sandwich ELISA or ELISPOT assay, when used in conjunction with the biotinylated XMG1.2 antibody (Cat. No. 505804) as the detecting antibody and recombinant mouse IFN-? (Cat. No. 575309) as the standard. The Ultra-LEAF™ purified antibody is suggested for ELISPOT capture. For ELISPOT Capture, the suggested use of this antibody is 1.0 - 4.0 µg/mL. ELISA or ELISPOT Detection: The biotinylated R4-6A2 antibody is useful as the detecting antibody in a sandwich ELISA or ELISPOT assay, when used in conjunction with the purified XMG1.2 antibody (Cat. Nos. 505802 505812) as the capture antibody and recombinant mouse IFN-? (Cat. No. 575309) as the standard. Neutralization 1,2,9 : The Ultra-LEAF™ purified antibody (Endotoxin 0.01 EU/µg, Azide-Free, 0.2 µm filtered) is recommended for neutralization of mouse IFN-? bioactivity in vivo and in vitro (Cat. Nos. 505708 - 505713). Additional reported applications (for the relevant formats) include: immunohistochemical staining 3,6,8 of acetone-fixed frozen tissue sections. Note: For testing mouse IFN-? in serum, plasma or supernatant, BioLegend s ELISA Max™ Sets (Cat. No. 430801 and 430804) are specially developed and recommended.
更多信息或购买 :
公司信息
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品,旨在加速生命科学领域的研发工作。