产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
纯化(无叠氮物)抗RNA聚合酶II RPB1
目录 :
664906
规格 :
100微克
价格 :
323美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
8WG16
反应物种 :
酵母菌目, fission yeast, 人类, 小鼠, 大鼠, brewer's yeast, roundworm
应用 :
免疫印迹, 免疫细胞化学, 免疫沉淀, 染色质免疫沉淀 , ChIP-Seq
更多信息或购买 :
文章摘录数: 63
出版应用/物种/样本/稀释参考文献
  • 染色质免疫沉淀 ; roundworm ; ; 图 4a
Das S, Ooi F, Cruz Corchado J, Fuller L, Weiner J, Prahlad V. Serotonin signaling by maternal neurons upon stress ensures progeny survival. elife. 2020;9: pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:200; 图 5a
  • 免疫印迹; 小鼠; 1:500; 图 3f
Hartenian E, Gilbertson S, Federspiel J, Cristea I, Glaunsinger B. RNA decay during gammaherpesvirus infection reduces RNA polymerase II occupancy of host promoters but spares viral promoters. PLoS Pathog. 2020;16:e1008269 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1g
Nishioka K, Miyazaki H, Soejima H. Unbiased shRNA screening, using a combination of FACS and high-throughput sequencing, enables identification of novel modifiers of Polycomb silencing. Sci Rep. 2018;8:12128 pubmed 出版商
  • 免疫印迹; brewer's yeast; 图 1c
Sdano M, Fulcher J, Palani S, Chandrasekharan M, Parnell T, Whitby F, et al. A novel SH2 recognition mechanism recruits Spt6 to the doubly phosphorylated RNA polymerase II linker at sites of transcription. elife. 2017;6: pubmed 出版商
  • 免疫印迹; brewer's yeast; 图 3c
Garavís M, González Polo N, Allepuz Fuster P, Louro J, Fernández Tornero C, Calvo O. Sub1 contacts the RNA polymerase II stalk to modulate mRNA synthesis. Nucleic Acids Res. 2017;45:2458-2471 pubmed 出版商
  • 免疫印迹; 人类; 图 3
Steingruber M, Kraut A, Socher E, Sticht H, Reichel A, Stamminger T, et al. Proteomic Interaction Patterns between Human Cyclins, the Cyclin-Dependent Kinase Ortholog pUL97 and Additional Cytomegalovirus Proteins. Viruses. 2016;8: pubmed 出版商
  • ChIP-Seq; 人类; 图 2
Rialdi A, Campisi L, Zhao N, Lagda A, Pietzsch C, Ho J, et al. Topoisomerase 1 inhibition suppresses inflammatory genes and protects from death by inflammation. Science. 2016;352:aad7993 pubmed 出版商
  • 染色质免疫沉淀 ; 小鼠; 图 1d
Bailus B, Pyles B, McAlister M, O Geen H, Lockwood S, Adams A, et al. Protein Delivery of an Artificial Transcription Factor Restores Widespread Ube3a Expression in an Angelman Syndrome Mouse Brain. Mol Ther. 2016;24:548-55 pubmed 出版商
  • ChIP-Seq; 人类; 图 2
Mannini L, C Lamaze F, Cucco F, Amato C, Quarantotti V, Rizzo I, et al. Mutant cohesin affects RNA polymerase II regulation in Cornelia de Lange syndrome. Sci Rep. 2015;5:16803 pubmed 出版商
  • ChIP-Seq; 小鼠; 图 2
  • 免疫沉淀; 小鼠; 图 s5
Masuda A, Takeda J, Okuno T, Okamoto T, Ohkawara B, Ito M, et al. Position-specific binding of FUS to nascent RNA regulates mRNA length. Genes Dev. 2015;29:1045-57 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2
Ide S, Déjardin J. End-targeting proteomics of isolated chromatin segments of a mammalian ribosomal RNA gene promoter. Nat Commun. 2015;6:6674 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Lama L, Seidl C, Ryan K. New insights into the promoterless transcription of DNA coligo templates by RNA polymerase III. Transcription. 2014;5:e27913 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Liang K, Gao X, Gilmore J, Florens L, Washburn M, Smith E, et al. Characterization of human cyclin-dependent kinase 12 (CDK12) and CDK13 complexes in C-terminal domain phosphorylation, gene transcription, and RNA processing. Mol Cell Biol. 2015;35:928-38 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
Stubbs S, Conrad N. Depletion of REF/Aly alters gene expression and reduces RNA polymerase II occupancy. Nucleic Acids Res. 2015;43:504-19 pubmed 出版商
  • 染色质免疫沉淀 ; 酵母菌目
Rosado Lugo J, Hampsey M. The Ssu72 phosphatase mediates the RNA polymerase II initiation-elongation transition. J Biol Chem. 2014;289:33916-26 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
Moquet Torcy G, Tolza C, Piechaczyk M, Jariel Encontre I. Transcriptional complexity and roles of Fra-1/AP-1 at the uPA/Plau locus in aggressive breast cancer. Nucleic Acids Res. 2014;42:11011-24 pubmed 出版商
  • 免疫印迹; fission yeast
Karakasili E, Burkert Kautzsch C, Kieser A, Sträßer K. Degradation of DNA damage-independently stalled RNA polymerase II is independent of the E3 ligase Elc1. Nucleic Acids Res. 2014;42:10503-15 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
  • 染色质免疫沉淀 ; 酵母菌目
  • 免疫沉淀; 酵母菌目
Mirón García M, Garrido Godino A, Martínez Fernández V, Fernández Pévida A, Cuevas Bermúdez A, Martín Expósito M, et al. The yeast prefoldin-like URI-orthologue Bud27 associates with the RSC nucleosome remodeler and modulates transcription. Nucleic Acids Res. 2014;42:9666-76 pubmed 出版商
  • 免疫印迹; 人类
Lodhi N, Kossenkov A, Tulin A. Bookmarking promoters in mitotic chromatin: poly(ADP-ribose)polymerase-1 as an epigenetic mark. Nucleic Acids Res. 2014;42:7028-38 pubmed 出版商
  • 免疫印迹; brewer's yeast
Gaillard H, Aguilera A. Cleavage factor I links transcription termination to DNA damage response and genome integrity maintenance in Saccharomyces cerevisiae. PLoS Genet. 2014;10:e1004203 pubmed 出版商
  • 染色质免疫沉淀 ; 小鼠; 5 ug/time
Konsavage W, Yochum G. The myc 3' wnt-responsive element suppresses colonic tumorigenesis. Mol Cell Biol. 2014;34:1659-69 pubmed 出版商
  • 染色质免疫沉淀 ; fission yeast
DeGennaro C, Alver B, Marguerat S, Stepanova E, Davis C, Bähler J, et al. Spt6 regulates intragenic and antisense transcription, nucleosome positioning, and histone modifications genome-wide in fission yeast. Mol Cell Biol. 2013;33:4779-92 pubmed 出版商
  • 染色质免疫沉淀 ; 人类
Kuwahara Y, Wei D, Durand J, Weissman B. SNF5 reexpression in malignant rhabdoid tumors regulates transcription of target genes by recruitment of SWI/SNF complexes and RNAPII to the transcription start site of their promoters. Mol Cancer Res. 2013;11:251-60 pubmed 出版商
  • 免疫印迹; 人类; 1:1,000
Medina R, Ghule P, Cruzat F, Barutcu A, Montecino M, Stein J, et al. Epigenetic control of cell cycle-dependent histone gene expression is a principal component of the abbreviated pluripotent cell cycle. Mol Cell Biol. 2012;32:3860-71 pubmed 出版商
  • 染色质免疫沉淀 ; 大鼠
DiNieri J, Wang X, Szutorisz H, Spano S, Kaur J, CASACCIA P, et al. Maternal cannabis use alters ventral striatal dopamine D2 gene regulation in the offspring. Biol Psychiatry. 2011;70:763-9 pubmed 出版商
See Y, Chen K, Fullwood M. MYC overexpression leads to increased chromatin interactions at super-enhancers and MYC binding sites. Genome Res. 2022;32:629-642 pubmed 出版商
Huang Z, Liang N, Goñi S, Damdimopoulos A, Wang C, Ballaire R, et al. The corepressors GPS2 and SMRT control enhancer and silencer remodeling via eRNA transcription during inflammatory activation of macrophages. Mol Cell. 2021;: pubmed 出版商
Vadivel C, Gluud M, Torres Rusillo S, Boding L, Willerslev Olsen A, Buus T, et al. JAK3 Is Expressed in the Nucleus of Malignant T Cells in Cutaneous T Cell Lymphoma (CTCL). Cancers (Basel). 2021;13: pubmed 出版商
Onishi R, Sato K, Murano K, Negishi L, Siomi H, Siomi M. Piwi suppresses transcription of Brahma-dependent transposons via Maelstrom in ovarian somatic cells. Sci Adv. 2020;6: pubmed 出版商
Cardoso da Silva R, Villar Fernández M, Vader G. Active transcription and Orc1 drive chromatin association of the AAA+ ATPase Pch2 during meiotic G2/prophase. PLoS Genet. 2020;16:e1008905 pubmed 出版商
Joo Y, Xue Y, Wang Y, McDevitt R, Sah N, Bossi S, et al. Topoisomerase 3β knockout mice show transcriptional and behavioural impairments associated with neurogenesis and synaptic plasticity. Nat Commun. 2020;11:3143 pubmed 出版商
Sen I, Zhou X, Chernobrovkin A, Puerta Cavanzo N, Kanno T, Salignon J, et al. DAF-16/FOXO requires Protein Phosphatase 4 to initiate transcription of stress resistance and longevity promoting genes. Nat Commun. 2020;11:138 pubmed 出版商
Calvanese V, Nguyen A, Bolan T, Vavilina A, Su T, Lee L, et al. MLLT3 governs human haematopoietic stem-cell self-renewal and engraftment. Nature. 2019;576:281-286 pubmed 出版商
Legrand N, Bretscher C, Zielke S, Wilke B, Daude M, Fritz B, et al. PPARβ/δ recruits NCOR and regulates transcription reinitiation of ANGPTL4. Nucleic Acids Res. 2019;47:9573-9591 pubmed 出版商
Wu S, Naar A. SREBP1-dependent de novo fatty acid synthesis gene expression is elevated in malignant melanoma and represents a cellular survival trait. Sci Rep. 2019;9:10369 pubmed 出版商
Catala M, Abou Elela S. Promoter-dependent nuclear RNA degradation ensures cell cycle-specific gene expression. Commun Biol. 2019;2:211 pubmed 出版商
Wu T, Shi L, Lowe A, Nicolls M, Kao P. Inducible expression of immediate early genes is regulated through dynamic chromatin association by NF45/ILF2 and NF90/NF110/ILF3. PLoS ONE. 2019;14:e0216042 pubmed 出版商
Rowley M, Lyu X, Rana V, Ando Kuri M, Karns R, Bosco G, et al. Condensin II Counteracts Cohesin and RNA Polymerase II in the Establishment of 3D Chromatin Organization. Cell Rep. 2019;26:2890-2903.e3 pubmed 出版商
Chi B, O Connell J, Iocolano A, Coady J, Yu Y, Gangopadhyay J, et al. The neurodegenerative diseases ALS and SMA are linked at the molecular level via the ASC-1 complex. Nucleic Acids Res. 2018;46:11939-11951 pubmed 出版商
Krause M, Love D, Ghosh S, Wang P, Yun S, Fukushige T, et al. Nutrient-Driven O-GlcNAcylation at Promoters Impacts Genome-Wide RNA Pol II Distribution. Front Endocrinol (Lausanne). 2018;9:521 pubmed 出版商
Akhrymuk I, Frolov I, Frolova E. Sindbis Virus Infection Causes Cell Death by nsP2-Induced Transcriptional Shutoff or by nsP3-Dependent Translational Shutoff. J Virol. 2018;92: pubmed 出版商
Kamada R, Yang W, Zhang Y, Patel M, Yang Y, Ouda R, et al. Interferon stimulation creates chromatin marks and establishes transcriptional memory. Proc Natl Acad Sci U S A. 2018;115:E9162-E9171 pubmed 出版商
Fuentes D, Swigut T, Wysocka J. Systematic perturbation of retroviral LTRs reveals widespread long-range effects on human gene regulation. elife. 2018;7: pubmed 出版商
Minocha R, Popova V, Kopytova D, Misiak D, Huttelmaier S, Georgieva S, et al. Mud2 functions in transcription by recruiting the Prp19 and TREX complexes to transcribed genes. Nucleic Acids Res. 2018;46:9749-9763 pubmed 出版商
Yu R, Wang X, Moazed D. Epigenetic inheritance mediated by coupling of RNAi and histone H3K9 methylation. Nature. 2018;558:615-619 pubmed 出版商
Gouot E, Bhat W, Rufiange A, Fournier E, Paquet E, Nourani A. Casein kinase 2 mediated phosphorylation of Spt6 modulates histone dynamics and regulates spurious transcription. Nucleic Acids Res. 2018;46:7612-7630 pubmed 出版商
Lee J, Shao N, Paik D, Wu H, Guo H, Termglinchan V, et al. SETD7 Drives Cardiac Lineage Commitment through Stage-Specific Transcriptional Activation. Cell Stem Cell. 2018;22:428-444.e5 pubmed 出版商
Rhie S, Yao L, Luo Z, Witt H, Schreiner S, Guo Y, et al. ZFX acts as a transcriptional activator in multiple types of human tumors by binding downstream of transcription start sites at the majority of CpG island promoters. Genome Res. 2018;: pubmed 出版商
Li S, Almeida A, Radebaugh C, Zhang L, Chen X, Huang L, et al. The elongation factor Spn1 is a multi-functional chromatin binding protein. Nucleic Acids Res. 2018;46:2321-2334 pubmed 出版商
Li P, Mitra S, Spolski R, Oh J, Liao W, Tang Z, et al. STAT5-mediated chromatin interactions in superenhancers activate IL-2 highly inducible genes: Functional dissection of the Il2ra gene locus. Proc Natl Acad Sci U S A. 2017;114:12111-12119 pubmed 出版商
García Benítez F, Gaillard H, Aguilera A. Physical proximity of chromatin to nuclear pores prevents harmful R loop accumulation contributing to maintain genome stability. Proc Natl Acad Sci U S A. 2017;114:10942-10947 pubmed 出版商
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Sood V, Cajigas I, D Urso A, Light W, Brickner J. Epigenetic Transcriptional Memory of GAL Genes Depends on Growth in Glucose and the Tup1 Transcription Factor in Saccharomyces cerevisiae. Genetics. 2017;206:1895-1907 pubmed 出版商
Dorighi K, Swigut T, Henriques T, Bhanu N, Scruggs B, Nady N, et al. Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation. Mol Cell. 2017;66:568-576.e4 pubmed 出版商
Crickard J, Lee J, Lee T, Reese J. The elongation factor Spt4/5 regulates RNA polymerase II transcription through the nucleosome. Nucleic Acids Res. 2017;45:6362-6374 pubmed 出版商
Cruz Molina S, Respuela P, Tebartz C, Kolovos P, Nikolic M, Fueyo R, et al. PRC2 Facilitates the Regulatory Topology Required for Poised Enhancer Function during Pluripotent Stem Cell Differentiation. Cell Stem Cell. 2017;20:689-705.e9 pubmed 出版商
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产品信息
抗原 :
RNA聚合酶II RPB1
Apps. Abbrev. :
西方墨点法, 免疫细胞化学, ChIP, FA, 免疫沉淀
目录 :
664906
克隆 :
8WG16
产品 :
纯化(无叠氮物)抗RNA聚合酶II RPB1
抗体亚型 :
小鼠IgG2a
其他名称 :
RNA polymerase II sub-unit 1, RPB1, CTD repeat YSPTSPS, C- terminal domain repeat YSPTSPS, DNA-directed RNA polymerase II subunit A, RNA-directed RNA polymerase II subunit RPB1, POLR2A, POLR2
规格 :
100微克
价格(美元) :
323美元
反应物种 :
人类, 小鼠
克隆性 :
单克隆
宿主 :
小鼠
共轭标签/标签/标记 :
PUREAF
免疫原 :
Wheat germ RNA Polymerase II
应用注释 :
Clone 8WG16 recognizes YSPTSPS in the C-terminal domain. The antibody cross-reacts with wheat, yeast, mouse, c. elegans, x. laevis , and most eukaryotic RNAPII. Additional reported applications (for the relevant formats) include: chromatin immunoprecipitation, functional assay, and immunoprecipatation.
更多信息或购买 :
公司信息
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品,旨在加速生命科学领域的研发工作。