产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
Go-ChIP-Grade™ Purified anti-RNA Polymerase II RPB1
目录 :
664911
规格 :
25微克
价格 :
75美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
8WG16
反应物种 :
fission yeast, 人类, 小鼠, brewer's yeast, roundworm
应用 :
免疫印迹, 免疫细胞化学, 染色质免疫沉淀
更多信息或购买 :
文章摘录数: 34
出版应用/物种/样本/稀释参考文献
  • 免疫细胞化学; 小鼠; 1:200; 图 5a
  • 免疫印迹; 小鼠; 1:500; 图 3f
Hartenian E, Gilbertson S, Federspiel J, Cristea I, Glaunsinger B. RNA decay during gammaherpesvirus infection reduces RNA polymerase II occupancy of host promoters but spares viral promoters. PLoS Pathog. 2020;16:e1008269 pubmed 出版商
  • 免疫印迹; 小鼠; 图 1g
Nishioka K, Miyazaki H, Soejima H. Unbiased shRNA screening, using a combination of FACS and high-throughput sequencing, enables identification of novel modifiers of Polycomb silencing. Sci Rep. 2018;8:12128 pubmed 出版商
  • 免疫印迹; brewer's yeast; 图 1c
Sdano M, Fulcher J, Palani S, Chandrasekharan M, Parnell T, Whitby F, et al. A novel SH2 recognition mechanism recruits Spt6 to the doubly phosphorylated RNA polymerase II linker at sites of transcription. elife. 2017;6: pubmed 出版商
Bi L, Xie C, Jiao L, Jin S, Hnit S, Mu Y, et al. CPF impedes cell cycle re-entry of quiescent lung cancer cells through transcriptional suppression of FACT and c-MYC. J Cell Mol Med. 2020;24:2229-2239 pubmed 出版商
Sen I, Zhou X, Chernobrovkin A, Puerta Cavanzo N, Kanno T, Salignon J, et al. DAF-16/FOXO requires Protein Phosphatase 4 to initiate transcription of stress resistance and longevity promoting genes. Nat Commun. 2020;11:138 pubmed 出版商
Serbyn N, Noireterre A, Bagdiul I, Plank M, Michel A, Loewith R, et al. The Aspartic Protease Ddi1 Contributes to DNA-Protein Crosslink Repair in Yeast. Mol Cell. 2020;77:1066-1079.e9 pubmed 出版商
Calvanese V, Nguyen A, Bolan T, Vavilina A, Su T, Lee L, et al. MLLT3 governs human haematopoietic stem-cell self-renewal and engraftment. Nature. 2019;576:281-286 pubmed 出版商
Bayles I, Krajewska M, Pontius W, Saiakhova A, Morrow J, Bartels C, et al. Ex vivo screen identifies CDK12 as a metastatic vulnerability in osteosarcoma. J Clin Invest. 2019;129:4377-4392 pubmed 出版商
Zhou K, Shi H, Lyu R, Wylder A, Matuszek Ż, Pan J, et al. Regulation of Co-transcriptional Pre-mRNA Splicing by m6A through the Low-Complexity Protein hnRNPG. Mol Cell. 2019;76:70-81.e9 pubmed 出版商
Wu S, Naar A. SREBP1-dependent de novo fatty acid synthesis gene expression is elevated in malignant melanoma and represents a cellular survival trait. Sci Rep. 2019;9:10369 pubmed 出版商
Wu T, Shi L, Lowe A, Nicolls M, Kao P. Inducible expression of immediate early genes is regulated through dynamic chromatin association by NF45/ILF2 and NF90/NF110/ILF3. PLoS ONE. 2019;14:e0216042 pubmed 出版商
Dronamraju R, Kerschner J, Peck S, Hepperla A, Adams A, Hughes K, et al. Casein Kinase II Phosphorylation of Spt6 Enforces Transcriptional Fidelity by Maintaining Spn1-Spt6 Interaction. Cell Rep. 2018;25:3476-3489.e5 pubmed 出版商
Chi B, O Connell J, Iocolano A, Coady J, Yu Y, Gangopadhyay J, et al. The neurodegenerative diseases ALS and SMA are linked at the molecular level via the ASC-1 complex. Nucleic Acids Res. 2018;46:11939-11951 pubmed 出版商
Krause M, Love D, Ghosh S, Wang P, Yun S, Fukushige T, et al. Nutrient-Driven O-GlcNAcylation at Promoters Impacts Genome-Wide RNA Pol II Distribution. Front Endocrinol (Lausanne). 2018;9:521 pubmed 出版商
Akhrymuk I, Frolov I, Frolova E. Sindbis Virus Infection Causes Cell Death by nsP2-Induced Transcriptional Shutoff or by nsP3-Dependent Translational Shutoff. J Virol. 2018;92: pubmed 出版商
Kamada R, Yang W, Zhang Y, Patel M, Yang Y, Ouda R, et al. Interferon stimulation creates chromatin marks and establishes transcriptional memory. Proc Natl Acad Sci U S A. 2018;115:E9162-E9171 pubmed 出版商
Fuentes D, Swigut T, Wysocka J. Systematic perturbation of retroviral LTRs reveals widespread long-range effects on human gene regulation. elife. 2018;7: pubmed 出版商
Minocha R, Popova V, Kopytova D, Misiak D, Huttelmaier S, Georgieva S, et al. Mud2 functions in transcription by recruiting the Prp19 and TREX complexes to transcribed genes. Nucleic Acids Res. 2018;46:9749-9763 pubmed 出版商
Dronamraju R, Hepperla A, Shibata Y, Adams A, Magnuson T, Davis I, et al. Spt6 Association with RNA Polymerase II Directs mRNA Turnover During Transcription. Mol Cell. 2018;70:1054-1066.e4 pubmed 出版商
Yu R, Wang X, Moazed D. Epigenetic inheritance mediated by coupling of RNAi and histone H3K9 methylation. Nature. 2018;558:615-619 pubmed 出版商
Gouot E, Bhat W, Rufiange A, Fournier E, Paquet E, Nourani A. Casein kinase 2 mediated phosphorylation of Spt6 modulates histone dynamics and regulates spurious transcription. Nucleic Acids Res. 2018;46:7612-7630 pubmed 出版商
Li P, Mitra S, Spolski R, Oh J, Liao W, Tang Z, et al. STAT5-mediated chromatin interactions in superenhancers activate IL-2 highly inducible genes: Functional dissection of the Il2ra gene locus. Proc Natl Acad Sci U S A. 2017;114:12111-12119 pubmed 出版商
García Benítez F, Gaillard H, Aguilera A. Physical proximity of chromatin to nuclear pores prevents harmful R loop accumulation contributing to maintain genome stability. Proc Natl Acad Sci U S A. 2017;114:10942-10947 pubmed 出版商
Jih G, Iglesias N, Currie M, Bhanu N, Paulo J, Gygi S, et al. Unique roles for histone H3K9me states in RNAi and heritable silencing of transcription. Nature. 2017;547:463-467 pubmed 出版商
Sood V, Cajigas I, D Urso A, Light W, Brickner J. Epigenetic Transcriptional Memory of GAL Genes Depends on Growth in Glucose and the Tup1 Transcription Factor in Saccharomyces cerevisiae. Genetics. 2017;206:1895-1907 pubmed 出版商
Dorighi K, Swigut T, Henriques T, Bhanu N, Scruggs B, Nady N, et al. Mll3 and Mll4 Facilitate Enhancer RNA Synthesis and Transcription from Promoters Independently of H3K4 Monomethylation. Mol Cell. 2017;66:568-576.e4 pubmed 出版商
Crickard J, Lee J, Lee T, Reese J. The elongation factor Spt4/5 regulates RNA polymerase II transcription through the nucleosome. Nucleic Acids Res. 2017;45:6362-6374 pubmed 出版商
Cruz Molina S, Respuela P, Tebartz C, Kolovos P, Nikolic M, Fueyo R, et al. PRC2 Facilitates the Regulatory Topology Required for Poised Enhancer Function during Pluripotent Stem Cell Differentiation. Cell Stem Cell. 2017;20:689-705.e9 pubmed 出版商
Klopf E, Schmidt H, Clauder Münster S, Steinmetz L, Schüller C. INO80 represses osmostress induced gene expression by resetting promoter proximal nucleosomes. Nucleic Acids Res. 2017;45:3752-3766 pubmed 出版商
Garavís M, González Polo N, Allepuz Fuster P, Louro J, Fernández Tornero C, Calvo O. Sub1 contacts the RNA polymerase II stalk to modulate mRNA synthesis. Nucleic Acids Res. 2017;45:2458-2471 pubmed 出版商
Ahn J, Rechsteiner A, Strome S, Kelly W. A Conserved Nuclear Cyclophilin Is Required for Both RNA Polymerase II Elongation and Co-transcriptional Splicing in Caenorhabditis elegans. PLoS Genet. 2016;12:e1006227 pubmed 出版商
Tsai S, Chang Y, Swamy K, Chiang R, Huang D. GAGA factor, a positive regulator of global gene expression, modulates transcriptional pausing and organization of upstream nucleosomes. Epigenetics Chromatin. 2016;9:32 pubmed 出版商
Shi L, Godfrey W, Lin J, Zhao G, Kao P. NF90 regulates inducible IL-2 gene expression in T cells. J Exp Med. 2007;204:971-7 pubmed
Funayama R, Saito M, Tanobe H, Ishikawa F. Loss of linker histone H1 in cellular senescence. J Cell Biol. 2006;175:869-80 pubmed
产品信息
抗原 :
RNA聚合酶II RPB1
Apps. Abbrev. :
ChIP, 西方墨点法, 免疫细胞化学
目录 :
664911
克隆 :
8WG16
产品 :
Go-ChIP-Grade™ Purified anti-RNA Polymerase II RPB1
抗体亚型 :
小鼠IgG2a
其他名称 :
RNA polymerase II sub-unit 1, RPB1, CTD repeat YSPTSPS, C- terminal domain repeat YSPTSPS, DNA-directed RNA polymerase II subunit A, RNA-directed RNA polymerase II subunit RPB1, POLR2A, POLR2
规格 :
25微克
价格(美元) :
75美元
反应物种 :
Human, Yeast, Wheat, Mouse, C. elegans, X. laevis, most other eukaryotic RNAPII
克隆性 :
单克隆
宿主 :
小鼠
共轭标签/标签/标记 :
GOCHIPGRADE
免疫原 :
Wheat germ RNA Polymerase II
应用注释 :
Clone 8WG16 recognizes YSPTSPS in the C-terminal domain. The antibody cross-reacts with wheat, yeast, mouse, c. elegans, x. laevis , and most eukaryotic RNAPII. Additional reported applications (for the relevant formats) include: chromatin immunoprecipitation, functional assay, and immunoprecipatation.
更多信息或购买 :
公司信息
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品,旨在加速生命科学领域的研发工作。