产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
Purified (azide-free) anti-Neurofilament H (NF-H), Nonphosphorylated
目录 :
801702
规格 :
25微升
价格 :
95美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
SMI 32
反应物种 :
African green monkey, 人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫组化, 免疫细胞化学, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 94
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 人类; 图 1
Cserép C, Pósfai B, Lénárt N, Fekete R, László Z, Lele Z, et al. Microglia monitor and protect neuronal function through specialized somatic purinergic junctions. Science. 2020;367:528-537 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:800; 图 9d
Stefanov A, Novelli E, Strettoi E. Inner retinal preservation in the photoinducible I307N rhodopsin mutant mouse, a model of autosomal dominant retinitis pigmentosa. J Comp Neurol. 2020;528:1502-1522 pubmed 出版商
  • 免疫组化; African green monkey; 1:500; 图 1a
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Bailey R, Armao D, Nagabhushan Kalburgi S, Gray S. Development of Intrathecal AAV9 Gene Therapy for Giant Axonal Neuropathy. Mol Ther Methods Clin Dev. 2018;9:160-171 pubmed 出版商
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Butler B, Sunstrum J, Lomber S. Modified Origins of Cortical Projections to the Superior Colliculus in the Deaf: Dispersion of Auditory Efferents. J Neurosci. 2018;38:4048-4058 pubmed 出版商
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Risner M, Pasini S, Cooper M, Lambert W, Calkins D. Axogenic mechanism enhances retinal ganglion cell excitability during early progression in glaucoma. Proc Natl Acad Sci U S A. 2018;115:E2393-E2402 pubmed 出版商
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Joyce M, Barbas H. Cortical Connections Position Primate Area 25 as a Keystone for Interoception, Emotion, and Memory. J Neurosci. 2018;38:1677-1698 pubmed 出版商
Weng Y, Wang X, An R, Cassin J, Vissers C, Liu Y, et al. Epitranscriptomic m6A Regulation of Axon Regeneration in the Adult Mammalian Nervous System. Neuron. 2018;97:313-325.e6 pubmed 出版商
Ito K, Ohkawara B, Yagi H, Nakashima H, Tsushima M, Ota K, et al. Lack of Fgf18 causes abnormal clustering of motor nerve terminals at the neuromuscular junction with reduced acetylcholine receptor clusters. Sci Rep. 2018;8:434 pubmed 出版商
Litvina E, Chen C. Functional Convergence at the Retinogeniculate Synapse. Neuron. 2017;96:330-338.e5 pubmed 出版商
Krieger B, Qiao M, Rousso D, Sanes J, Meister M. Four alpha ganglion cell types in mouse retina: Function, structure, and molecular signatures. PLoS ONE. 2017;12:e0180091 pubmed 出版商
Norante R, Massimino M, Lorenzon P, De Mario A, Peggion C, Vicario M, et al. Generation and validation of novel adeno-associated viral vectors for the analysis of Ca2+ homeostasis in motor neurons. Sci Rep. 2017;7:6521 pubmed 出版商
Jacquier A, Delorme C, Belotti E, Juntas Morales R, Solé G, Dubourg O, et al. Cryptic amyloidogenic elements in mutant NEFH causing Charcot-Marie-Tooth 2 trigger aggresome formation and neuronal death. Acta Neuropathol Commun. 2017;5:55 pubmed 出版商
Cumberworth S, Barrie J, Cunningham M, de Figueiredo D, Schultz V, Wilder Smith A, et al. Zika virus tropism and interactions in myelinating neural cell cultures: CNS cells and myelin are preferentially affected. Acta Neuropathol Commun. 2017;5:50 pubmed 出版商
Corsini S, Tortora M, Rauti R, Nistri A. Nicotine protects rat hypoglossal motoneurons from excitotoxic death via downregulation of connexin 36. Cell Death Dis. 2017;8:e2881 pubmed 出版商
Akopian A, Kumar S, Ramakrishnan H, Roy K, Viswanathan S, Bloomfield S. Targeting neuronal gap junctions in mouse retina offers neuroprotection in glaucoma. J Clin Invest. 2017;127:2647-2661 pubmed 出版商
Schultz V, van der Meer F, Wrzos C, Scheidt U, Bahn E, Stadelmann C, et al. Acutely damaged axons are remyelinated in multiple sclerosis and experimental models of demyelination. Glia. 2017;65:1350-1360 pubmed 出版商
Llorens F, Thüne K, Sikorska B, Schmitz M, Tahir W, Fernández Borges N, et al. Altered Ca2+ homeostasis induces Calpain-Cathepsin axis activation in sporadic Creutzfeldt-Jakob disease. Acta Neuropathol Commun. 2017;5:35 pubmed 出版商
Himmelein S, Lindemann A, Sinicina I, Horn A, Brandt T, Strupp M, et al. Differential Involvement during Latent Herpes Simplex Virus 1 Infection of the Superior and Inferior Divisions of the Vestibular Ganglia: Implications for Vestibular Neuritis. J Virol. 2017;91: pubmed 出版商
Karamita M, Barnum C, Mobius W, TANSEY M, Szymkowski D, Lassmann H, et al. Therapeutic inhibition of soluble brain TNF promotes remyelination by increasing myelin phagocytosis by microglia. JCI Insight. 2017;2: pubmed 出版商
Sun D, Moore S, Jakobs T. Optic nerve astrocyte reactivity protects function in experimental glaucoma and other nerve injuries. J Exp Med. 2017;214:1411-1430 pubmed 出版商
Hoye M, Koval E, Wegener A, Hyman T, Yang C, O Brien D, et al. MicroRNA Profiling Reveals Marker of Motor Neuron Disease in ALS Models. J Neurosci. 2017;37:5574-5586 pubmed 出版商
Woo C, Maier V, Davey R, Brennan J, Li G, Brothers J, et al. Gene activation of SMN by selective disruption of lncRNA-mediated recruitment of PRC2 for the treatment of spinal muscular atrophy. Proc Natl Acad Sci U S A. 2017;114:E1509-E1518 pubmed 出版商
Li X, Wang Z, Tan L, Wang Y, Lu C, Chen R, et al. Correcting miR92a-vGAT-Mediated GABAergic Dysfunctions Rescues Human Tau-Induced Anxiety in Mice. Mol Ther. 2017;25:140-152 pubmed 出版商
Lanz T, Williams S, Stojic A, Iwantscheff S, Sonner J, Grabitz C, et al. Tryptophan-2,3-Dioxygenase (TDO) deficiency is associated with subclinical neuroprotection in a mouse model of multiple sclerosis. Sci Rep. 2017;7:41271 pubmed 出版商
Bukreeva I, Campi G, Fratini M, Spano R, Bucci D, Battaglia G, et al. Quantitative 3D investigation of Neuronal network in mouse spinal cord model. Sci Rep. 2017;7:41054 pubmed 出版商
Feng L, Puyang Z, Chen H, Liang P, Troy J, Liu X. Overexpression of Brain-Derived Neurotrophic Factor Protects Large Retinal Ganglion Cells After Optic Nerve Crush in Mice. Eneuro. 2017;4: pubmed 出版商
Petrozziello T, Secondo A, Tedeschi V, Esposito A, Sisalli M, Scorziello A, et al. ApoSOD1 lacking dismutase activity neuroprotects motor neurons exposed to beta-methylamino-L-alanine through the Ca2+/Akt/ERK1/2 prosurvival pathway. Cell Death Differ. 2017;24:511-522 pubmed 出版商
Casanovas A, Salvany S, Lahoz V, Tarabal O, Piedrafita L, Sabater R, et al. Neuregulin 1-ErbB module in C-bouton synapses on somatic motor neurons: molecular compartmentation and response to peripheral nerve injury. Sci Rep. 2017;7:40155 pubmed 出版商
Toonen J, Solga A, Ma Y, Gutmann D. Estrogen activation of microglia underlies the sexually dimorphic differences in Nf1 optic glioma-induced retinal pathology. J Exp Med. 2017;214:17-25 pubmed 出版商
Scholl T, Mühlebner A, Ricken G, Gruber V, Fabing A, Samueli S, et al. Impaired oligodendroglial turnover is associated with myelin pathology in focal cortical dysplasia and tuberous sclerosis complex. Brain Pathol. 2017;27:770-780 pubmed 出版商
Donkels C, Pfeifer D, Janz P, Huber S, Nakagawa J, Prinz M, et al. Whole Transcriptome Screening Reveals Myelination Deficits in Dysplastic Human Temporal Neocortex. Cereb Cortex. 2017;27:1558-1572 pubmed 出版商
Ou Y, Jo R, Ullian E, Wong R, Della Santina L. Selective Vulnerability of Specific Retinal Ganglion Cell Types and Synapses after Transient Ocular Hypertension. J Neurosci. 2016;36:9240-52 pubmed 出版商
Rizzo F, Ronchi D, Salani S, Nizzardo M, Fortunato F, Bordoni A, et al. Selective mitochondrial depletion, apoptosis resistance, and increased mitophagy in human Charcot-Marie-Tooth 2A motor neurons. Hum Mol Genet. 2016;25:4266-4281 pubmed 出版商
Ho R, Sances S, Gowing G, Amoroso M, O Rourke J, Sahabian A, et al. ALS disrupts spinal motor neuron maturation and aging pathways within gene co-expression networks. Nat Neurosci. 2016;19:1256-67 pubmed 出版商
Azeez I, Olopade F, Laperchia C, Andrioli A, Scambi I, Onwuka S, et al. Regional Myelin and Axon Damage and Neuroinflammation in the Adult Mouse Brain After Long-Term Postnatal Vanadium Exposure. J Neuropathol Exp Neurol. 2016;75:843-54 pubmed 出版商
Yoo M, Kim T, Yoon Y, Koh J. Autism phenotypes in ZnT3 null mice: Involvement of zinc dyshomeostasis, MMP-9 activation and BDNF upregulation. Sci Rep. 2016;6:28548 pubmed 出版商
Brambilla L, Guidotti G, Martorana F, Iyer A, Aronica E, Valori C, et al. Disruption of the astrocytic TNFR1-GDNF axis accelerates motor neuron degeneration and disease progression in amyotrophic lateral sclerosis. Hum Mol Genet. 2016;25:3080-3095 pubmed
Luna G, Keeley P, Reese B, Linberg K, Lewis G, Fisher S. Astrocyte structural reactivity and plasticity in models of retinal detachment. Exp Eye Res. 2016;150:4-21 pubmed 出版商
Körner S, Böselt S, Wichmann K, Thau Habermann N, Zapf A, Knippenberg S, et al. The Axon Guidance Protein Semaphorin 3A Is Increased in the Motor Cortex of Patients With Amyotrophic Lateral Sclerosis. J Neuropathol Exp Neurol. 2016;: pubmed
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Patitucci T, Ebert A. SMN deficiency does not induce oxidative stress in SMA iPSC-derived astrocytes or motor neurons. Hum Mol Genet. 2016;25:514-23 pubmed 出版商
Berry R, Qu J, John S, Howell G, Jakobs T. Synapse Loss and Dendrite Remodeling in a Mouse Model of Glaucoma. PLoS ONE. 2015;10:e0144341 pubmed 出版商
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产品信息
抗原 :
Neurofilament H NF-H
Apps. Abbrev. :
免疫组化-P, 西方墨点法, 微阵列试剂盒断层显像, 免疫细胞化学
目录 :
801702
克隆 :
SMI 32
产品 :
Purified (azide-free) anti-Neurofilament H (NF-H), Nonphosphorylated
抗体亚型 :
小鼠IgG1
其他名称 :
Neurofilament heavy polypeptide, NF-H, 200 kD neurofilament protein, neurofilament triplet H protein
规格 :
25微升
价格(美元) :
95美元
反应物种 :
Human, Mouse, Rat, Other mammalian
克隆性 :
单克隆
宿主 :
小鼠
共轭标签/标签/标记 :
PUREAF
应用注释 :
Additional reported applications (for the relevant formats) include Western blotting 6 , immunohistochemistry 4,5 , immunocytochemistry 1,2,3, 7 , array tomography 8 . Cross-reactivity to monkey tissue has been reported in the literature 4 . This antibody reacts with a nonphosphorylated epitope in neurofilament H of most mammalian species. The reaction is masked when the epitope is phosphorylated. The staining of isolated neurofilament preparations is greatly intensified upon dephosphorylation. Immunocytochemically, SMI 32 visualizes neuronal cell bodies, dendrites, and some thick axons in the central and peripheral nervous systems. However, thin axons are not revealed. Other cells and tissues are unreactive. The antibody distinguishes three subdivisions of the macaque precentral motor cortex. The greater size of the left versus the right superior temporal lobe was found to be due to increased axonal myelination and not due to increased number of glial cells or SMI 32-enumerated neurons, suggesting that the specialization for language in the left temporal lobe is related to increased speed of signal transmission. In cultures of murine cortex, SMI 32 labels a neuronal population with enhanced vulnerability to kainate toxicity most of which are GABAergic and reveal kainate-activated Ca 2+ uptake.
更多信息或购买 :
公司信息
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品,旨在加速生命科学领域的研发工作。