产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
Purified (azide-free) anti-β-Amyloid, 1-16
目录 :
803003
规格 :
1毫升
价格 :
1780美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
6E10
反应物种 :
African green monkey, 仓鼠, 人类, 小鼠, 大鼠, fruit fly
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫组化-自由浮动切片, 其他
更多信息或购买 :
文章摘录数: 311
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 小鼠; 图 6a
Jeong A, Cheng S, Zhong R, Bennett D, Bergo M, Li L. Protein farnesylation is upregulated in Alzheimer's human brains and neuron-specific suppression of farnesyltransferase mitigates pathogenic processes in Alzheimer's model mice. Acta Neuropathol Commun. 2021;9:129 pubmed 出版商
  • 酶联免疫吸附测定; 小鼠
Tournissac M, Vu T, Vrabic N, Hozer C, Tremblay C, Mélançon K, et al. Repurposing beta-3 adrenergic receptor agonists for Alzheimer's disease: beneficial effects in a mouse model. Alzheimers Res Ther. 2021;13:103 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:500; 图 5c
Kazuki Y, Gao F, Li Y, Moyer A, Devenney B, Hiramatsu K, et al. A non-mosaic transchromosomic mouse model of down syndrome carrying the long arm of human chromosome 21. elife. 2020;9: pubmed 出版商
  • 免疫组化; 小鼠; 图 1b
Wander C, Tseng J, Song S, Al Housseiny H, Tart D, Ajit A, et al. The Accumulation of Tau-Immunoreactive Hippocampal Granules and Corpora Amylacea Implicates Reactive Glia in Tau Pathogenesis during Aging. iScience. 2020;23:101255 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:1000; 图 4h
Rodriguez Ortiz C, Prieto G, Martini A, Forner S, Trujillo Estrada L, LaFerla F, et al. miR-181a negatively modulates synaptic plasticity in hippocampal cultures and its inhibition rescues memory deficits in a mouse model of Alzheimer's disease. Aging Cell. 2020;19:e13118 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:1000; 图 2a
Eede P, Obst J, Benke E, Yvon Durocher G, Richard B, Gimber N, et al. Interleukin-12/23 deficiency differentially affects pathology in male and female Alzheimer's disease-like mice. EMBO Rep. 2020;21:e48530 pubmed 出版商
  • 免疫组化; 小鼠; 1:1000; 图 3s1
  • 免疫印迹; 小鼠; 1:1000; 图 6e
El Gaamouch F, Audrain M, Lin W, Beckmann N, Jiang C, Hariharan S, et al. VGF-derived peptide TLQP-21 modulates microglial function through C3aR1 signaling pathways and reduces neuropathology in 5xFAD mice. Mol Neurodegener. 2020;15:4 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:1000; 图 2a
Rice H, Marcassa G, Chrysidou I, Horré K, Young Pearse T, Müller U, et al. Contribution of GABAergic interneurons to amyloid-β plaque pathology in an APP knock-in mouse model. Mol Neurodegener. 2020;15:3 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:2500; 图 4a
Latimer C, Burke B, Liachko N, Currey H, Kilgore M, Gibbons L, et al. Resistance and resilience to Alzheimer's disease pathology are associated with reduced cortical pTau and absence of limbic-predominant age-related TDP-43 encephalopathy in a community-based cohort. Acta Neuropathol Commun. 2019;7:9 pubmed 出版商
  • 免疫印迹; 小鼠; 图 3c
Pan R, Ma J, Kong X, Wang X, Li S, Qi X, et al. Sodium rutin ameliorates Alzheimer's disease-like pathology by enhancing microglial amyloid-β clearance. Sci Adv. 2019;5:eaau6328 pubmed 出版商
  • 免疫印迹; 小鼠; 1:11,000; 图 3b
Sri S, Pegasiou C, Cave C, Hough K, Wood N, Gomez Nicola D, et al. Emergence of synaptic and cognitive impairment in a mature-onset APP mouse model of Alzheimer's disease. Acta Neuropathol Commun. 2019;7:25 pubmed 出版商
  • 免疫组化; 小鼠; 1:300; 图 2d
Rosenzweig N, Dvir Szternfeld R, Tsitsou Kampeli A, Keren Shaul H, Ben Yehuda H, Weill Raynal P, et al. PD-1/PD-L1 checkpoint blockade harnesses monocyte-derived macrophages to combat cognitive impairment in a tauopathy mouse model. Nat Commun. 2019;10:465 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:200; 图 3c
Beckelman B, Yang W, Kasica N, Zimmermann H, Zhou X, Keene C, et al. Genetic reduction of eEF2 kinase alleviates pathophysiology in Alzheimer's disease model mice. J Clin Invest. 2019;129:820-833 pubmed 出版商
  • 免疫印迹; 小鼠; 1:10,000; 图 3h
Reichenbach N, Delekate A, Plescher M, Schmitt F, Krauss S, Blank N, et al. Inhibition of Stat3-mediated astrogliosis ameliorates pathology in an Alzheimer's disease model. EMBO Mol Med. 2019;11: pubmed 出版商
  • 免疫印迹; 人类; 图 3a
Hartl D, May P, Gu W, Mayhaus M, Pichler S, Spaniol C, et al. A rare loss-of-function variant of ADAM17 is associated with late-onset familial Alzheimer disease. Mol Psychiatry. 2018;: pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 图 1a
Baglietto Vargas D, Prieto G, Limon A, Forner S, Rodriguez Ortiz C, Ikemura K, et al. Impaired AMPA signaling and cytoskeletal alterations induce early synaptic dysfunction in a mouse model of Alzheimer's disease. Aging Cell. 2018;17:e12791 pubmed 出版商
  • 免疫印迹; 小鼠; ; 图 6t
Reichenbach N, Delekate A, Breithausen B, Keppler K, Poll S, Schulte T, et al. P2Y1 receptor blockade normalizes network dysfunction and cognition in an Alzheimer's disease model. J Exp Med. 2018;215:1649-1663 pubmed 出版商
  • 免疫印迹; 人类; 图 1a
Mukadam A, Breusegem S, Seaman M. Analysis of novel endosome-to-Golgi retrieval genes reveals a role for PLD3 in regulating endosomal protein sorting and amyloid precursor protein processing. Cell Mol Life Sci. 2018;75:2613-2625 pubmed 出版商
  • 免疫组化-冰冻切片; African green monkey; 1:12,000; 图 4a
Cramer P, Gentzel R, Tanis K, Vardigan J, Wang Y, Connolly B, et al. Aging African green monkeys manifest transcriptional, pathological, and cognitive hallmarks of human Alzheimer's disease. Neurobiol Aging. 2018;64:92-106 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2500; 图 5a
Chiang A, Fowler S, Reddy R, Pletnikova O, Troncoso J, Sherman M, et al. Discrete Pools of Oligomeric Amyloid-β Track with Spatial Learning Deficits in a Mouse Model of Alzheimer Amyloidosis. Am J Pathol. 2018;188:739-756 pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Benvegnù S, Wahle T, Dotti C. E3 ligase mahogunin (MGRN1) influences amyloid precursor protein maturation and secretion. Oncotarget. 2017;8:89439-89450 pubmed 出版商
  • 免疫组化-冰冻切片; African green monkey; 1:7500; 图 1a
Edler M, Sherwood C, Meindl R, Hopkins W, Ely J, Erwin J, et al. Aged chimpanzees exhibit pathologic hallmarks of Alzheimer's disease. Neurobiol Aging. 2017;59:107-120 pubmed 出版商
  • 免疫细胞化学; 人类; 1:1000; 图 6a
  • 免疫印迹; 人类; 图 s1a
Tseng J, Xie L, Song S, Xie Y, Allen L, Ajit D, et al. The Deacetylase HDAC6 Mediates Endogenous Neuritic Tau Pathology. Cell Rep. 2017;20:2169-2183 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 4a
Koistinen N, Edlund A, Menon P, Ivanova E, Bacanu S, Iverfeldt K. Nuclear localization of amyloid-? precursor protein-binding protein Fe65 is dependent on regulated intramembrane proteolysis. PLoS ONE. 2017;12:e0173888 pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 图 4j
Gardenal E, Chiarini A, Armato U, Dal Pra I, Verkhratsky A, Rodriguez J. Increased Calcium-Sensing Receptor Immunoreactivity in the Hippocampus of a Triple Transgenic Mouse Model of Alzheimer's Disease. Front Neurosci. 2017;11:81 pubmed 出版商
  • 免疫组化; 人类; 1:1000; 图 5a
Zheng T, Pu J, Chen Y, Mao Y, Guo Z, Pan H, et al. Plasma Exosomes Spread and Cluster Around ?-Amyloid Plaques in an Animal Model of Alzheimer's Disease. Front Aging Neurosci. 2017;9:12 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 1e
Mellott T, Huleatt O, Shade B, Pender S, Liu Y, Slack B, et al. Perinatal Choline Supplementation Reduces Amyloidosis and Increases Choline Acetyltransferase Expression in the Hippocampus of the APPswePS1dE9 Alzheimer's Disease Model Mice. PLoS ONE. 2017;12:e0170450 pubmed 出版商
  • 免疫细胞化学; 人类; 1:100; 图 5b
Chapuis J, Flaig A, Grenier Boley B, Eysert F, Pottiez V, Deloison G, et al. Genome-wide, high-content siRNA screening identifies the Alzheimer's genetic risk factor FERMT2 as a major modulator of APP metabolism. Acta Neuropathol. 2017;133:955-966 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:100; 图 1d
  • 免疫印迹; 小鼠; 1:1000; 图 1f
Yang S, Lee D, Shin J, Lee S, Baek S, Kim J, et al. Nec-1 alleviates cognitive impairment with reduction of Aβ and tau abnormalities in APP/PS1 mice. EMBO Mol Med. 2017;9:61-77 pubmed 出版商
  • 免疫印迹; 人类; 图 3b
Tapia Rojas C, Burgos P, Inestrosa N. Inhibition of Wnt signaling induces amyloidogenic processing of amyloid precursor protein and the production and aggregation of Amyloid-? (A?)42 peptides. J Neurochem. 2016;139:1175-1191 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠; 1:100; 图 3
Steffen J, Krohn M, Paarmann K, Schwitlick C, Brüning T, Marreiros R, et al. Revisiting rodent models: Octodon degus as Alzheimer's disease model?. Acta Neuropathol Commun. 2016;4:91 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4
Xu J, De Winter F, Farrokhi C, Rockenstein E, Mante M, Adame A, et al. Neuregulin 1 improves cognitive deficits and neuropathology in an Alzheimer's disease model. Sci Rep. 2016;6:31692 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 2
Marzesco A, Flötenmeyer M, Bühler A, Obermüller U, Staufenbiel M, Jucker M, et al. Highly potent intracellular membrane-associated A? seeds. Sci Rep. 2016;6:28125 pubmed 出版商
  • 免疫印迹; 人类; 图 1
Bao J, Zheng L, Zhang Q, Li X, Zhang X, Li Z, et al. Deacetylation of TFEB promotes fibrillar A? degradation by upregulating lysosomal biogenesis in microglia. Protein Cell. 2016;7:417-33 pubmed 出版商
  • 免疫印迹; fruit fly ; 图 1
Ando K, Maruko Otake A, Ohtake Y, Hayashishita M, Sekiya M, Iijima K. Stabilization of Microtubule-Unbound Tau via Tau Phosphorylation at Ser262/356 by Par-1/MARK Contributes to Augmentation of AD-Related Phosphorylation and Aβ42-Induced Tau Toxicity. PLoS Genet. 2016;12:e1005917 pubmed 出版商
  • 免疫沉淀; 人类; 图 4
Reinert J, Richard B, Klafki H, Friedrich B, Bayer T, Wiltfang J, et al. Deposition of C-terminally truncated Aβ species Aβ37 and Aβ39 in Alzheimer's disease and transgenic mouse models. Acta Neuropathol Commun. 2016;4:24 pubmed 出版商
  • 免疫组化-自由浮动切片; 人类; 1:1000; 表 2
Perez S, Sherwood C, Cranfield M, Erwin J, Mudakikwa A, Hof P, et al. Early Alzheimer's disease-type pathology in the frontal cortex of wild mountain gorillas (Gorilla beringei beringei). Neurobiol Aging. 2016;39:195-201 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 4
  • 免疫印迹; 小鼠; 1:1000; 图 4
Peng Y, Kim M, Hullinger R, O Riordan K, Burger C, Pehar M, et al. Improved proteostasis in the secretory pathway rescues Alzheimer's disease in the mouse. Brain. 2016;139:937-52 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 表 1
  • 免疫印迹; 小鼠; 1:1000; 表 1
Piedrahita D, Castro Álvarez J, Boudreau R, Villegas Lanau A, Kosik K, Gallego Gómez J, et al. β-Secretase 1's Targeting Reduces Hyperphosphorilated Tau, Implying Autophagy Actors in 3xTg-AD Mice. Front Cell Neurosci. 2015;9:498 pubmed 出版商
  • 免疫印迹; 仓鼠; 图 7
Chen A, Kim S, Shepardson N, Patel S, Hong S, Selkoe D. Physical and functional interaction between the α- and γ-secretases: A new model of regulated intramembrane proteolysis. J Cell Biol. 2015;211:1157-76 pubmed 出版商
  • 免疫印迹; fruit fly ; 1:2000; 图 2O
Lee S, Bang S, Hong Y, Lee J, Jeong H, Park S, et al. The calcineurin inhibitor Sarah (Nebula) exacerbates Aβ42 phenotypes in a Drosophila model of Alzheimer's disease. Dis Model Mech. 2016;9:295-306 pubmed 出版商
  • 免疫印迹; 人类; 1:1500; 图 3
  • 免疫印迹; 小鼠; 1:1500; 图 3
Xu G, Ran Y, Fromholt S, Fu C, Yachnis A, Golde T, et al. Murine Aβ over-production produces diffuse and compact Alzheimer-type amyloid deposits. Acta Neuropathol Commun. 2015;3:72 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 5e
Ostapchenko V, Chen M, Guzman M, Xie Y, Lavine N, Fan J, et al. The Transient Receptor Potential Melastatin 2 (TRPM2) Channel Contributes to β-Amyloid Oligomer-Related Neurotoxicity and Memory Impairment. J Neurosci. 2015;35:15157-69 pubmed 出版商
  • 免疫组化; 小鼠; 1:500; 图 4
Sabogal Guáqueta A, Osorio E, Cardona Gómez G. Linalool reverses neuropathological and behavioral impairments in old triple transgenic Alzheimer's mice. Neuropharmacology. 2016;102:111-20 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:1000; 图 1
Cherry J, Olschowka J, O Banion M. Arginase 1+ microglia reduce Aβ plaque deposition during IL-1β-dependent neuroinflammation. J Neuroinflammation. 2015;12:203 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Kumar R, Nordberg A, Darreh Shori T. Amyloid-β peptides act as allosteric modulators of cholinergic signalling through formation of soluble BAβACs. Brain. 2016;139:174-92 pubmed 出版商
  • 酶联免疫吸附测定; 人类; 2 ug/ml; 图 6
Miners J, Palmer J, Love S. Pathophysiology of Hypoperfusion of the Precuneus in Early Alzheimer's Disease. Brain Pathol. 2016;26:533-41 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6a
Kokiko Cochran O, Ransohoff L, Veenstra M, Lee S, Saber M, Sikora M, et al. Altered Neuroinflammation and Behavior after Traumatic Brain Injury in a Mouse Model of Alzheimer's Disease. J Neurotrauma. 2016;33:625-40 pubmed 出版商
  • 免疫组化; 人类; 表 1
Montine T, Monsell S, Beach T, Bigio E, Bu Y, Cairns N, et al. Multisite assessment of NIA-AA guidelines for the neuropathologic evaluation of Alzheimer's disease. Alzheimers Dement. 2016;12:164-169 pubmed 出版商
  • 免疫印迹; fruit fly
Nevzglyadova O, Mikhailova E, Amen T, Zenin V, Artemov A, Kostyleva E, et al. Yeast red pigment modifies Amyloid beta growth in Alzheimer disease models in both Saccharomyces cerevisiae and Drosophila melanogaster. Amyloid. 2015;22:100-11 pubmed 出版商
  • 其他; 人类; 1:100; 图 2a
Cuddy L, Seah C, Pasternak S, Rylett R. Differential regulation of the high-affinity choline transporter by wild-type and Swedish mutant amyloid precursor protein. J Neurochem. 2015;134:769-82 pubmed 出版商
  • 免疫沉淀; 人类
Hernandez Guillamon M, Mawhirt S, Blais S, Montaner J, Neubert T, Rostagno A, et al. Sequential Amyloid-β Degradation by the Matrix Metalloproteases MMP-2 and MMP-9. J Biol Chem. 2015;290:15078-91 pubmed 出版商
  • 免疫组化; 小鼠; 1:500
Yetman M, Lillehaug S, Bjaalie J, Leergaard T, Jankowsky J. Transgene expression in the Nop-tTA driver line is not inherently restricted to the entorhinal cortex. Brain Struct Funct. 2016;221:2231-49 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000
Leinenga G, Götz J. Scanning ultrasound removes amyloid-β and restores memory in an Alzheimer's disease mouse model. Sci Transl Med. 2015;7:278ra33 pubmed 出版商
  • 免疫印迹; 大鼠; 1:500
Jay T, Miller C, Cheng P, Graham L, Bemiller S, Broihier M, et al. TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer's disease mouse models. J Exp Med. 2015;212:287-95 pubmed 出版商
  • 免疫组化; 小鼠; 1:500
Sabogal Guáqueta A, Muñoz Manco J, Ramírez Pineda J, Lamprea Rodriguez M, Osorio E, Cardona Gómez G. The flavonoid quercetin ameliorates Alzheimer's disease pathology and protects cognitive and emotional function in aged triple transgenic Alzheimer's disease model mice. Neuropharmacology. 2015;93:134-45 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:600
Wu Z, Yang B, Liu C, Liang G, Eckenhoff M, Liu W, et al. Long-term dantrolene treatment reduced intraneuronal amyloid in aged Alzheimer triple transgenic mice. Alzheimer Dis Assoc Disord. 2015;29:184-191 pubmed 出版商
  • 免疫组化; 大鼠
  • 免疫印迹; 大鼠; 1:1000
Kang E, Cho J. Effects of treadmill exercise on brain insulin signaling and β-amyloid in intracerebroventricular streptozotocin induced-memory impairment in rats. J Exerc Nutrition Biochem. 2014;18:89-96 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:300
  • 酶联免疫吸附测定; 人类; 1:1000
Ashby E, Miners J, Kumar S, Walter J, Love S, Kehoe P. Investigation of Aβ phosphorylated at serine 8 (pAβ) in Alzheimer's disease, dementia with Lewy bodies and vascular dementia. Neuropathol Appl Neurobiol. 2015;41:428-44 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Vingtdeux V, Tanis J, Chandakkar P, Zhao H, Dreses Werringloer U, Campagne F, et al. Effect of the CALHM1 G330D and R154H human variants on the control of cytosolic Ca2+ and Aβ levels. PLoS ONE. 2014;9:e112484 pubmed 出版商
  • 免疫印迹; 人类; 1:2000
Thomzig A, Wagenführ K, Daus M, Joncic M, Schulz Schaeffer W, Thanheiser M, et al. Decontamination of medical devices from pathological amyloid-?-, tau- and ?-synuclein aggregates. Acta Neuropathol Commun. 2014;2:151 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:1000
  • 免疫印迹; 小鼠; 1:1000
Joshi G, Gan K, Johnson D, Johnson J. Increased Alzheimer's disease-like pathology in the APP/ PS1ΔE9 mouse model lacking Nrf2 through modulation of autophagy. Neurobiol Aging. 2015;36:664-79 pubmed 出版商
  • 免疫细胞化学; 人类
  • 酶联免疫吸附测定; 人类
  • 免疫印迹; 人类
Maloney J, Bainbridge T, Gustafson A, Zhang S, Kyauk R, Steiner P, et al. Molecular mechanisms of Alzheimer disease protection by the A673T allele of amyloid precursor protein. J Biol Chem. 2014;289:30990-1000 pubmed 出版商
  • 免疫组化-自由浮动切片; 人类; 1:2500
  • 免疫印迹; 人类; 1:2500
Lue L, Schmitz C, Serrano G, Sue L, Beach T, Walker D. TREM2 Protein Expression Changes Correlate with Alzheimer's Disease Neurodegenerative Pathologies in Post-Mortem Temporal Cortices. Brain Pathol. 2015;25:469-80 pubmed 出版商
  • 免疫细胞化学; 小鼠
Dunn H, Ager R, Baglietto Vargas D, Cheng D, Kitazawa M, Cribbs D, et al. Restoration of lipoxin A4 signaling reduces Alzheimer's disease-like pathology in the 3xTg-AD mouse model. J Alzheimers Dis. 2015;43:893-903 pubmed 出版商
  • 酶联免疫吸附测定; 小鼠
Hanenberg M, McAfoose J, Kulic L, Welt T, Wirth F, Parizek P, et al. Amyloid-β peptide-specific DARPins as a novel class of potential therapeutics for Alzheimer disease. J Biol Chem. 2014;289:27080-9 pubmed 出版商
  • 免疫细胞化学; 人类; 1:50
Kohler C, Dinekov M, Götz J. Granulovacuolar degeneration and unfolded protein response in mouse models of tauopathy and A? amyloidosis. Neurobiol Dis. 2014;71:169-79 pubmed 出版商
  • 免疫印迹; 人类
Zhou Y, Hayashi I, Wong J, Tugusheva K, Renger J, Zerbinatti C. Intracellular clusterin interacts with brain isoforms of the bridging integrator 1 and with the microtubule-associated protein Tau in Alzheimer's disease. PLoS ONE. 2014;9:e103187 pubmed 出版商
  • 免疫印迹; 人类; 1:5000
Sadleir K, Eimer W, Kaufman R, Osten P, Vassar R. Genetic inhibition of phosphorylation of the translation initiation factor eIF2α does not block Aβ-dependent elevation of BACE1 and APP levels or reduce amyloid pathology in a mouse model of Alzheimer's disease. PLoS ONE. 2014;9:e101643 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2500
Fowler S, Chiang A, Savjani R, Larson M, Sherman M, Schuler D, et al. Genetic modulation of soluble A? rescues cognitive and synaptic impairment in a mouse model of Alzheimer's disease. J Neurosci. 2014;34:7871-85 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500
Shilling D, Müller M, Takano H, Mak D, Abel T, Coulter D, et al. Suppression of InsP3 receptor-mediated Ca2+ signaling alleviates mutant presenilin-linked familial Alzheimer's disease pathogenesis. J Neurosci. 2014;34:6910-23 pubmed 出版商
  • 免疫组化; 人类; 1 ug/ml
Xiong Z, Thangavel R, Kempuraj D, Yang E, Zaheer S, Zaheer A. Alzheimer's disease: evidence for the expression of interleukin-33 and its receptor ST2 in the brain. J Alzheimers Dis. 2014;40:297-308 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Bana L, Minniti S, Salvati E, Sesana S, Zambelli V, Cagnotto A, et al. Liposomes bi-functionalized with phosphatidic acid and an ApoE-derived peptide affect A? aggregation features and cross the blood-brain-barrier: implications for therapy of Alzheimer disease. Nanomedicine. 2014;10:1583-90 pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠
  • 免疫印迹; 小鼠
Medeiros R, Castello N, Cheng D, Kitazawa M, Baglietto Vargas D, Green K, et al. ?7 Nicotinic receptor agonist enhances cognition in aged 3xTg-AD mice with robust plaques and tangles. Am J Pathol. 2014;184:520-9 pubmed 出版商
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产品信息
抗原 :
乙淀粉样蛋白1-16
Apps. Abbrev. :
Western Blotting, Direct ELISA, IHC-P, IHC-F, EM, ICC
目录 :
803003
克隆 :
6E10
产品 :
Purified (azide-free) anti-β-Amyloid, 1-16
抗体亚型 :
Mouse IgG1, κ
其他名称 :
AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2, Amyloid beta A4 protein, preA4, protease, peptidase nexin-II, beta-amyloid peptide, alzheimer disease amyloid protein, cerebral vascular amyloid peptide, APP, Amyloid Precursor Protein
规格 :
1毫升
价格(美元) :
1780美元
反应物种 :
人类
克隆性 :
单克隆
宿主 :
小鼠
共轭标签/标签/标记 :
PUREAF
应用注释 :
This antibody is reactive to amino acid residue 1-16 of beta amyloid. The epitope lies within amino acids 3-8 of beta amyloid (EFRHDS). This antibody clone has been reported for use in immunohistochemistry of free-floating sections 2,13 .
更多信息或购买 :
公司信息
BioLegend
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San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品,旨在加速生命科学领域的研发工作。