产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
Alexa Fluor® 488 anti-β-Amyloid, 1-16
目录 :
803013
规格 :
200微升
价格 :
678美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
AF488
克隆名称 :
6E10
反应物种 :
African green monkey, 人类, 小鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫组化-自由浮动切片
更多信息或购买 :
文章摘录数: 23
出版应用/物种/样本/稀释参考文献
  • 酶联免疫吸附测定; 小鼠
Tournissac M, Vu T, Vrabic N, Hozer C, Tremblay C, Mélançon K, et al. Repurposing beta-3 adrenergic receptor agonists for Alzheimer's disease: beneficial effects in a mouse model. Alzheimers Res Ther. 2021;13:103 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:2500; 图 4a
Latimer C, Burke B, Liachko N, Currey H, Kilgore M, Gibbons L, et al. Resistance and resilience to Alzheimer's disease pathology are associated with reduced cortical pTau and absence of limbic-predominant age-related TDP-43 encephalopathy in a community-based cohort. Acta Neuropathol Commun. 2019;7:9 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
  • 免疫组化; 人类
Lin J, Izar B, Wang S, Yapp C, Mei S, Shah P, et al. Highly multiplexed immunofluorescence imaging of human tissues and tumors using t-CyCIF and conventional optical microscopes. elife. 2018;7: pubmed 出版商
  • 免疫印迹; 人类; 图 3a
Hartl D, May P, Gu W, Mayhaus M, Pichler S, Spaniol C, et al. A rare loss-of-function variant of ADAM17 is associated with late-onset familial Alzheimer disease. Mol Psychiatry. 2018;: pubmed 出版商
  • 免疫组化-冰冻切片; African green monkey; 1:100; 图 4a
Cramer P, Gentzel R, Tanis K, Vardigan J, Wang Y, Connolly B, et al. Aging African green monkeys manifest transcriptional, pathological, and cognitive hallmarks of human Alzheimer's disease. Neurobiol Aging. 2018;64:92-106 pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Benvegnù S, Wahle T, Dotti C. E3 ligase mahogunin (MGRN1) influences amyloid precursor protein maturation and secretion. Oncotarget. 2017;8:89439-89450 pubmed 出版商
  • 免疫组化-自由浮动切片; 人类; 图 4d
Ruan C, Liu J, Yang M, Saadipour K, Zeng Y, Liao H, et al. Sortilin inhibits amyloid pathology by regulating non-specific degradation of APP. Exp Neurol. 2018;299:75-85 pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 图 4b
Gardenal E, Chiarini A, Armato U, Dal Pra I, Verkhratsky A, Rodriguez J. Increased Calcium-Sensing Receptor Immunoreactivity in the Hippocampus of a Triple Transgenic Mouse Model of Alzheimer's Disease. Front Neurosci. 2017;11:81 pubmed 出版商
Lee J, Ostalecki C, Oberstein T, Schierer S, Zinser E, Eberhardt M, et al. Alzheimer's disease protease-containing plasma extracellular vesicles transfer to the hippocampus via the choroid plexus. EBioMedicine. 2022;77:103903 pubmed 出版商
Chen W, Lu A, Craessaerts K, Pavie B, Sala Frigerio C, Corthout N, et al. Spatial Transcriptomics and In Situ Sequencing to Study Alzheimer's Disease. Cell. 2020;182:976-991.e19 pubmed 出版商
Abe Y, Ikegawa N, Yoshida K, Muramatsu K, Hattori S, Kawai K, et al. Behavioral and electrophysiological evidence for a neuroprotective role of aquaporin-4 in the 5xFAD transgenic mice model. Acta Neuropathol Commun. 2020;8:67 pubmed 出版商
Vaquero M, Cuesta S, Anerillas C, Altés G, Ribera J, Basson M, et al. Sprouty1 Controls Genitourinary Development via its N-Terminal Tyrosine. J Am Soc Nephrol. 2019;30:1398-1411 pubmed 出版商
Paolicelli R, Jawaid A, Henstridge C, Valeri A, Merlini M, Robinson J, et al. TDP-43 Depletion in Microglia Promotes Amyloid Clearance but Also Induces Synapse Loss. Neuron. 2017;95:297-308.e6 pubmed 出版商
Saito S, Yamamoto Y, Maki T, Hattori Y, Ito H, Mizuno K, et al. Taxifolin inhibits amyloid-β oligomer formation and fully restores vascular integrity and memory in cerebral amyloid angiopathy. Acta Neuropathol Commun. 2017;5:26 pubmed 出版商
Fujita K, Motoki K, Tagawa K, Chen X, Hama H, Nakajima K, et al. HMGB1, a pathogenic molecule that induces neurite degeneration via TLR4-MARCKS, is a potential therapeutic target for Alzheimer's disease. Sci Rep. 2016;6:31895 pubmed 出版商
Omata Y, Tharasegaran S, Lim Y, Yamasaki Y, Ishigaki Y, Tatsuno T, et al. Expression of amyloid-β in mouse cochlear hair cells causes an early-onset auditory defect in high-frequency sound perception. Aging (Albany NY). 2016;8:427-39 pubmed
Forny Germano L, Lyra e Silva N, Batista A, Brito Moreira J, Gralle M, Boehnke S, et al. Alzheimer's disease-like pathology induced by amyloid-β oligomers in nonhuman primates. J Neurosci. 2014;34:13629-43 pubmed 出版商
Gowert N, Donner L, Chatterjee M, Eisele Y, Towhid S, Münzer P, et al. Blood platelets in the progression of Alzheimer's disease. PLoS ONE. 2014;9:e90523 pubmed 出版商
Zheng Y, Wang Q, Xiao B, Lu Q, Wang Y, Wang X. Involvement of receptor tyrosine kinase Tyro3 in amyloidogenic APP processing and ?-amyloid deposition in Alzheimer's disease models. PLoS ONE. 2012;7:e39035 pubmed 出版商
Abramowski D, Rabe S, Upadhaya A, Reichwald J, Danner S, Staab D, et al. Transgenic expression of intraneuronal A?42 but not A?40 leads to cellular A? lesions, degeneration, and functional impairment without typical Alzheimer's disease pathology. J Neurosci. 2012;32:1273-83 pubmed 出版商
Thakker D, Weatherspoon M, Harrison J, Keene T, Lane D, KAEMMERER W, et al. Intracerebroventricular amyloid-beta antibodies reduce cerebral amyloid angiopathy and associated micro-hemorrhages in aged Tg2576 mice. Proc Natl Acad Sci U S A. 2009;106:4501-6 pubmed 出版商
Oddo S, Caccamo A, Green K, Liang K, Tran L, Chen Y, et al. Chronic nicotine administration exacerbates tau pathology in a transgenic model of Alzheimer's disease. Proc Natl Acad Sci U S A. 2005;102:3046-51 pubmed
Herzig M, Winkler D, Burgermeister P, Pfeifer M, Kohler E, Schmidt S, et al. Abeta is targeted to the vasculature in a mouse model of hereditary cerebral hemorrhage with amyloidosis. Nat Neurosci. 2004;7:954-60 pubmed
产品信息
抗原 :
乙淀粉样蛋白1-16
Apps. Abbrev. :
免疫组化-P
目录 :
803013
克隆 :
6E10
产品 :
Alexa Fluor® 488 anti-β-Amyloid, 1-16
抗体亚型 :
Mouse IgG1, κ
其他名称 :
AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2, Amyloid beta A4 protein, preA4, protease, peptidase nexin-II, beta-amyloid peptide, alzheimer disease amyloid protein, cerebral vascular amyloid peptide, APP, Amyloid Precursor Protein
规格 :
200微升
价格(美元) :
678美元
反应物种 :
人类
克隆性 :
单克隆
宿主 :
小鼠
共轭标签/标签/标记 :
A488
应用注释 :
This antibody is reactive to amino acid residue 1-16 of beta amyloid. The epitope lies within amino acids 3-8 of beta amyloid (EFRHDS). This antibody clone has been reported for use in immunohistochemistry of free-floating sections 2,13 .
更多信息或购买 :
公司信息
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品,旨在加速生命科学领域的研发工作。