产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
Anti-β-Amyloid, 1-16
目录 :
803015
规格 :
200微升
价格 :
1054美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
6E10
反应物种 :
仓鼠, 人类, 小鼠, 大鼠, fruit fly , 猕猴
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学, 免疫沉淀, 免疫组化-石蜡切片, 免疫组化-冰冻切片, 免疫组化-自由浮动切片, 其他
更多信息或购买 :
文章摘录数: 113
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 人类; 1:500; 图 1a
  • 免疫组化-冰冻切片; 小鼠; 1:500; 图 6c
Zhao P, Xu Y, Jiang L, Fan X, Ku Z, Li L, et al. LILRB2-mediated TREM2 signaling inhibition suppresses microglia functions. Mol Neurodegener. 2022;17:44 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 s4b
Marengo L, Armbrust F, Schoenherr C, Storck S, Schmitt U, Zampar S, et al. Meprin β knockout reduces brain Aβ levels and rescues learning and memory impairments in the APP/lon mouse model for Alzheimer's disease. Cell Mol Life Sci. 2022;79:168 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:100; 图 4e
Villanueva E, Tresse E, Liu Y, Duarte J, Jimenez Duran G, Ejlerskov P, et al. Neuronal TNFα, Not α-Syn, Underlies PDD-Like Disease Progression in IFNβ-KO Mice. Ann Neurol. 2021;90:789-807 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:400; 图 1a
Zhang J, Wu N, Wang S, Yao Z, Xiao F, Lu J, et al. Neuronal loss and microgliosis are restricted to the core of Aβ deposits in mouse models of Alzheimer's disease. Aging Cell. 2021;20:e13380 pubmed 出版商
  • 酶联免疫吸附测定; 小鼠
Tournissac M, Vu T, Vrabic N, Hozer C, Tremblay C, Mélançon K, et al. Repurposing beta-3 adrenergic receptor agonists for Alzheimer's disease: beneficial effects in a mouse model. Alzheimers Res Ther. 2021;13:103 pubmed 出版商
  • 免疫组化; 小鼠; 图 s3b
Son G, Yoo S, Kang S, Rasheed A, Jung D, Park H, et al. Region-specific amyloid-β accumulation in the olfactory system influences olfactory sensory neuronal dysfunction in 5xFAD mice. Alzheimers Res Ther. 2021;13:4 pubmed 出版商
  • 免疫组化; 人类; 1:1000; 图 1a
Zhang X, Wang R, Hu D, Sun X, Fujioka H, Lundberg K, et al. Oligodendroglial glycolytic stress triggers inflammasome activation and neuropathology in Alzheimer's disease. Sci Adv. 2020;6: pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:2500; 图 4a
Latimer C, Burke B, Liachko N, Currey H, Kilgore M, Gibbons L, et al. Resistance and resilience to Alzheimer's disease pathology are associated with reduced cortical pTau and absence of limbic-predominant age-related TDP-43 encephalopathy in a community-based cohort. Acta Neuropathol Commun. 2019;7:9 pubmed 出版商
  • 免疫印迹; 人类; 图 3a
Hartl D, May P, Gu W, Mayhaus M, Pichler S, Spaniol C, et al. A rare loss-of-function variant of ADAM17 is associated with late-onset familial Alzheimer disease. Mol Psychiatry. 2018;: pubmed 出版商
  • 免疫印迹; 人类; 图 2a
Benvegnù S, Wahle T, Dotti C. E3 ligase mahogunin (MGRN1) influences amyloid precursor protein maturation and secretion. Oncotarget. 2017;8:89439-89450 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 4a
Koistinen N, Edlund A, Menon P, Ivanova E, Bacanu S, Iverfeldt K. Nuclear localization of amyloid-? precursor protein-binding protein Fe65 is dependent on regulated intramembrane proteolysis. PLoS ONE. 2017;12:e0173888 pubmed 出版商
  • 免疫印迹; 小鼠; 图 2a
Croft C, Wade M, Kurbatskaya K, Mastrandreas P, Hughes M, Phillips E, et al. Membrane association and release of wild-type and pathological tau from organotypic brain slice cultures. Cell Death Dis. 2017;8:e2671 pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 图 4b
Gardenal E, Chiarini A, Armato U, Dal Pra I, Verkhratsky A, Rodriguez J. Increased Calcium-Sensing Receptor Immunoreactivity in the Hippocampus of a Triple Transgenic Mouse Model of Alzheimer's Disease. Front Neurosci. 2017;11:81 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:1000; 图 s2a
Huang S, Mao J, Ding K, Zhou Y, Zeng X, Yang W, et al. Polysaccharides from Ganoderma lucidum Promote Cognitive Function and Neural Progenitor Proliferation in Mouse Model of Alzheimer's Disease. Stem Cell Reports. 2017;8:84-94 pubmed 出版商
  • 免疫组化; 人类; 1:2000; 表 1
Kordower J, Goetz C, Chu Y, Halliday G, Nicholson D, Musial T, et al. Robust graft survival and normalized dopaminergic innervation do not obligate recovery in a Parkinson disease patient. Ann Neurol. 2017;81:46-57 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000
Zhang H, Sun S, Wu L, Pchitskaya E, Zakharova O, Fon Tacer K, et al. Store-Operated Calcium Channel Complex in Postsynaptic Spines: A New Therapeutic Target for Alzheimer's Disease Treatment. J Neurosci. 2016;36:11837-11850 pubmed
  • 免疫印迹; 人类; 图 3b
Tapia Rojas C, Burgos P, Inestrosa N. Inhibition of Wnt signaling induces amyloidogenic processing of amyloid precursor protein and the production and aggregation of Amyloid-? (A?)42 peptides. J Neurochem. 2016;139:1175-1191 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4
Xu J, De Winter F, Farrokhi C, Rockenstein E, Mante M, Adame A, et al. Neuregulin 1 improves cognitive deficits and neuropathology in an Alzheimer's disease model. Sci Rep. 2016;6:31692 pubmed 出版商
  • 免疫印迹; 人类; 图 1b
Manocha G, Floden A, Rausch K, Kulas J, McGregor B, Rojanathammanee L, et al. APP Regulates Microglial Phenotype in a Mouse Model of Alzheimer's Disease. J Neurosci. 2016;36:8471-86 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:1000; 图 4
Li T, Braunstein K, Zhang J, Lau A, Sibener L, Deeble C, et al. The neuritic plaque facilitates pathological conversion of tau in an Alzheimer's disease mouse model. Nat Commun. 2016;7:12082 pubmed 出版商
  • 免疫印迹; 人类; 1:2000; 图 2
Marzesco A, Flötenmeyer M, Bühler A, Obermüller U, Staufenbiel M, Jucker M, et al. Highly potent intracellular membrane-associated A? seeds. Sci Rep. 2016;6:28125 pubmed 出版商
  • 免疫印迹; 小鼠; 图 s1
Chan E, Shetty M, Sajikumar S, Chen C, Soong T, Wong B. ApoE4 expression accelerates hippocampus-dependent cognitive deficits by enhancing Aβ impairment of insulin signaling in an Alzheimer's disease mouse model. Sci Rep. 2016;6:26119 pubmed 出版商
  • 免疫印迹; 人类; 图 2
Kurbatskaya K, Phillips E, Croft C, Dentoni G, Hughes M, Wade M, et al. Upregulation of calpain activity precedes tau phosphorylation and loss of synaptic proteins in Alzheimer's disease brain. Acta Neuropathol Commun. 2016;4:34 pubmed 出版商
  • 免疫印迹; fruit fly ; 图 1
Ando K, Maruko Otake A, Ohtake Y, Hayashishita M, Sekiya M, Iijima K. Stabilization of Microtubule-Unbound Tau via Tau Phosphorylation at Ser262/356 by Par-1/MARK Contributes to Augmentation of AD-Related Phosphorylation and Aβ42-Induced Tau Toxicity. PLoS Genet. 2016;12:e1005917 pubmed 出版商
  • 免疫沉淀; 人类; 图 4
Reinert J, Richard B, Klafki H, Friedrich B, Bayer T, Wiltfang J, et al. Deposition of C-terminally truncated Aβ species Aβ37 and Aβ39 in Alzheimer's disease and transgenic mouse models. Acta Neuropathol Commun. 2016;4:24 pubmed 出版商
  • 免疫组化; 小鼠; 1:100; 图 4
  • 免疫印迹; 小鼠; 1:1000; 图 4
Peng Y, Kim M, Hullinger R, O Riordan K, Burger C, Pehar M, et al. Improved proteostasis in the secretory pathway rescues Alzheimer's disease in the mouse. Brain. 2016;139:937-52 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 表 1
  • 免疫印迹; 人类; 1:1000; 表 1
Piedrahita D, Castro Álvarez J, Boudreau R, Villegas Lanau A, Kosik K, Gallego Gómez J, et al. β-Secretase 1's Targeting Reduces Hyperphosphorilated Tau, Implying Autophagy Actors in 3xTg-AD Mice. Front Cell Neurosci. 2015;9:498 pubmed 出版商
  • 免疫印迹; 仓鼠; 图 7
Chen A, Kim S, Shepardson N, Patel S, Hong S, Selkoe D. Physical and functional interaction between the α- and γ-secretases: A new model of regulated intramembrane proteolysis. J Cell Biol. 2015;211:1157-76 pubmed 出版商
  • 免疫印迹; fruit fly ; 1:2000; 图 2O
Lee S, Bang S, Hong Y, Lee J, Jeong H, Park S, et al. The calcineurin inhibitor Sarah (Nebula) exacerbates Aβ42 phenotypes in a Drosophila model of Alzheimer's disease. Dis Model Mech. 2016;9:295-306 pubmed 出版商
  • 免疫组化; 小鼠; 图 5
Wang J, Lu R, Yang J, Li H, He Z, Jing N, et al. TRPC6 specifically interacts with APP to inhibit its cleavage by γ-secretase and reduce Aβ production. Nat Commun. 2015;6:8876 pubmed 出版商
  • 免疫印迹; 人类; 1:1500; 图 3
  • 免疫印迹; 小鼠; 1:1500; 图 3
Xu G, Ran Y, Fromholt S, Fu C, Yachnis A, Golde T, et al. Murine Aβ over-production produces diffuse and compact Alzheimer-type amyloid deposits. Acta Neuropathol Commun. 2015;3:72 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000; 图 5e
Ostapchenko V, Chen M, Guzman M, Xie Y, Lavine N, Fan J, et al. The Transient Receptor Potential Melastatin 2 (TRPM2) Channel Contributes to β-Amyloid Oligomer-Related Neurotoxicity and Memory Impairment. J Neurosci. 2015;35:15157-69 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:1000; 图 1
Cherry J, Olschowka J, O Banion M. Arginase 1+ microglia reduce Aβ plaque deposition during IL-1β-dependent neuroinflammation. J Neuroinflammation. 2015;12:203 pubmed 出版商
  • 酶联免疫吸附测定; 人类; 2 ug/ml; 图 6
Miners J, Palmer J, Love S. Pathophysiology of Hypoperfusion of the Precuneus in Early Alzheimer's Disease. Brain Pathol. 2016;26:533-41 pubmed 出版商
  • 免疫组化; 小鼠; 图 9a
Gabbita S, Johnson M, Kobritz N, Eslami P, Poteshkina A, Varadarajan S, et al. Oral TNFα Modulation Alters Neutrophil Infiltration, Improves Cognition and Diminishes Tau and Amyloid Pathology in the 3xTgAD Mouse Model. PLoS ONE. 2015;10:e0137305 pubmed 出版商
  • 免疫印迹; 小鼠; 图 6a
Kokiko Cochran O, Ransohoff L, Veenstra M, Lee S, Saber M, Sikora M, et al. Altered Neuroinflammation and Behavior after Traumatic Brain Injury in a Mouse Model of Alzheimer's Disease. J Neurotrauma. 2016;33:625-40 pubmed 出版商
  • 免疫组化; 人类; 表 1
Montine T, Monsell S, Beach T, Bigio E, Bu Y, Cairns N, et al. Multisite assessment of NIA-AA guidelines for the neuropathologic evaluation of Alzheimer's disease. Alzheimers Dement. 2016;12:164-169 pubmed 出版商
  • 免疫印迹; 小鼠; 图 4
Lutzenberger M, Burwinkel M, Riemer C, Bode V, Baier M. Ablation of CCAAT/Enhancer-Binding Protein Delta (C/EBPD): Increased Plaque Burden in a Murine Alzheimer's Disease Model. PLoS ONE. 2015;10:e0134228 pubmed 出版商
  • 免疫印迹; fruit fly
Nevzglyadova O, Mikhailova E, Amen T, Zenin V, Artemov A, Kostyleva E, et al. Yeast red pigment modifies Amyloid beta growth in Alzheimer disease models in both Saccharomyces cerevisiae and Drosophila melanogaster. Amyloid. 2015;22:100-11 pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 1:200
Wang D, Kinoshita Y, Kinoshita C, Uo T, Sopher B, Cudaback E, et al. Loss of endophilin-B1 exacerbates Alzheimer's disease pathology. Brain. 2015;138:2005-19 pubmed 出版商
  • 其他; 人类; 1:100; 图 2a
Cuddy L, Seah C, Pasternak S, Rylett R. Differential regulation of the high-affinity choline transporter by wild-type and Swedish mutant amyloid precursor protein. J Neurochem. 2015;134:769-82 pubmed 出版商
  • 免疫印迹; 人类
Wang H, Sang N, Zhang C, Raghupathi R, Tanzi R, SAUNDERS A. Cathepsin L Mediates the Degradation of Novel APP C-Terminal Fragments. Biochemistry. 2015;54:2806-16 pubmed 出版商
  • 免疫沉淀; 人类
Hernandez Guillamon M, Mawhirt S, Blais S, Montaner J, Neubert T, Rostagno A, et al. Sequential Amyloid-β Degradation by the Matrix Metalloproteases MMP-2 and MMP-9. J Biol Chem. 2015;290:15078-91 pubmed 出版商
  • 免疫组化; 小鼠; 1:500
Yetman M, Lillehaug S, Bjaalie J, Leergaard T, Jankowsky J. Transgene expression in the Nop-tTA driver line is not inherently restricted to the entorhinal cortex. Brain Struct Funct. 2016;221:2231-49 pubmed 出版商
  • 免疫印迹; 大鼠
PajÄ…k B, Kania E, Orzechowski A. Nucleofection of rat pheochromocytoma PC-12 cells with human mutated beta-amyloid precursor protein gene (APP-sw) leads to reduced viability, autophagy-like process, and increased expression and secretion of beta amyloid. Biomed Res Int. 2015;2015:746092 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2000
Leinenga G, Götz J. Scanning ultrasound removes amyloid-β and restores memory in an Alzheimer's disease mouse model. Sci Transl Med. 2015;7:278ra33 pubmed 出版商
  • 免疫印迹; 大鼠; 1:500
Jay T, Miller C, Cheng P, Graham L, Bemiller S, Broihier M, et al. TREM2 deficiency eliminates TREM2+ inflammatory macrophages and ameliorates pathology in Alzheimer's disease mouse models. J Exp Med. 2015;212:287-95 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠; 1:600
Wu Z, Yang B, Liu C, Liang G, Eckenhoff M, Liu W, et al. Long-term dantrolene treatment reduced intraneuronal amyloid in aged Alzheimer triple transgenic mice. Alzheimer Dis Assoc Disord. 2015;29:184-191 pubmed 出版商
  • 免疫组化-石蜡切片; 人类; 1:300
  • 酶联免疫吸附测定; 人类; 1:1000
Ashby E, Miners J, Kumar S, Walter J, Love S, Kehoe P. Investigation of Aβ phosphorylated at serine 8 (pAβ) in Alzheimer's disease, dementia with Lewy bodies and vascular dementia. Neuropathol Appl Neurobiol. 2015;41:428-44 pubmed 出版商
  • 免疫组化; 小鼠; 1:1000
Hohsfield L, Daschil N, Orädd G, Strömberg I, Humpel C. Vascular pathology of 20-month-old hypercholesterolemia mice in comparison to triple-transgenic and APPSwDI Alzheimer's disease mouse models. Mol Cell Neurosci. 2014;63:83-95 pubmed
  • 免疫印迹; 人类; 1:1000
Vingtdeux V, Tanis J, Chandakkar P, Zhao H, Dreses Werringloer U, Campagne F, et al. Effect of the CALHM1 G330D and R154H human variants on the control of cytosolic Ca2+ and Aβ levels. PLoS ONE. 2014;9:e112484 pubmed 出版商
  • 免疫细胞化学; 小鼠; 1:1000
  • 免疫印迹; 小鼠; 1:1000
Joshi G, Gan K, Johnson D, Johnson J. Increased Alzheimer's disease-like pathology in the APP/ PS1ΔE9 mouse model lacking Nrf2 through modulation of autophagy. Neurobiol Aging. 2015;36:664-79 pubmed 出版商
  • 免疫印迹; 猕猴; 1:1000
Forny Germano L, Lyra e Silva N, Batista A, Brito Moreira J, Gralle M, Boehnke S, et al. Alzheimer's disease-like pathology induced by amyloid-β oligomers in nonhuman primates. J Neurosci. 2014;34:13629-43 pubmed 出版商
  • 免疫细胞化学; 人类
  • 酶联免疫吸附测定; 人类
  • 免疫印迹; 人类
Maloney J, Bainbridge T, Gustafson A, Zhang S, Kyauk R, Steiner P, et al. Molecular mechanisms of Alzheimer disease protection by the A673T allele of amyloid precursor protein. J Biol Chem. 2014;289:30990-1000 pubmed 出版商
  • 免疫细胞化学; 小鼠
Dunn H, Ager R, Baglietto Vargas D, Cheng D, Kitazawa M, Cribbs D, et al. Restoration of lipoxin A4 signaling reduces Alzheimer's disease-like pathology in the 3xTg-AD mouse model. J Alzheimers Dis. 2015;43:893-903 pubmed 出版商
  • 酶联免疫吸附测定; 小鼠
Hanenberg M, McAfoose J, Kulic L, Welt T, Wirth F, Parizek P, et al. Amyloid-β peptide-specific DARPins as a novel class of potential therapeutics for Alzheimer disease. J Biol Chem. 2014;289:27080-9 pubmed 出版商
  • 免疫细胞化学; 人类; 1:50
Kohler C, Dinekov M, Götz J. Granulovacuolar degeneration and unfolded protein response in mouse models of tauopathy and A? amyloidosis. Neurobiol Dis. 2014;71:169-79 pubmed 出版商
  • 免疫印迹; 大鼠; 1:2000
  • 免疫印迹; 小鼠; 1:2000
Zeldich E, Chen C, Colvin T, Bove Fenderson E, Liang J, Tucker Zhou T, et al. The neuroprotective effect of Klotho is mediated via regulation of members of the redox system. J Biol Chem. 2014;289:24700-15 pubmed 出版商
  • 免疫印迹; 人类; 1:5000
Sadleir K, Eimer W, Kaufman R, Osten P, Vassar R. Genetic inhibition of phosphorylation of the translation initiation factor eIF2α does not block Aβ-dependent elevation of BACE1 and APP levels or reduce amyloid pathology in a mouse model of Alzheimer's disease. PLoS ONE. 2014;9:e101643 pubmed 出版商
  • 免疫印迹; 小鼠; 1:2500
Fowler S, Chiang A, Savjani R, Larson M, Sherman M, Schuler D, et al. Genetic modulation of soluble A? rescues cognitive and synaptic impairment in a mouse model of Alzheimer's disease. J Neurosci. 2014;34:7871-85 pubmed 出版商
  • 免疫印迹; 小鼠; 1:500
Shilling D, Müller M, Takano H, Mak D, Abel T, Coulter D, et al. Suppression of InsP3 receptor-mediated Ca2+ signaling alleviates mutant presenilin-linked familial Alzheimer's disease pathogenesis. J Neurosci. 2014;34:6910-23 pubmed 出版商
  • 免疫组化; 人类; 1 ug/ml
Xiong Z, Thangavel R, Kempuraj D, Yang E, Zaheer S, Zaheer A. Alzheimer's disease: evidence for the expression of interleukin-33 and its receptor ST2 in the brain. J Alzheimers Dis. 2014;40:297-308 pubmed 出版商
  • 免疫印迹; 人类; 1:1000
Bana L, Minniti S, Salvati E, Sesana S, Zambelli V, Cagnotto A, et al. Liposomes bi-functionalized with phosphatidic acid and an ApoE-derived peptide affect A? aggregation features and cross the blood-brain-barrier: implications for therapy of Alzheimer disease. Nanomedicine. 2014;10:1583-90 pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠
  • 免疫印迹; 小鼠
Medeiros R, Castello N, Cheng D, Kitazawa M, Baglietto Vargas D, Green K, et al. ?7 Nicotinic receptor agonist enhances cognition in aged 3xTg-AD mice with robust plaques and tangles. Am J Pathol. 2014;184:520-9 pubmed 出版商
  • 免疫组化-冰冻切片; 小鼠; 1:1500
ElAli A, Theriault P, Prefontaine P, Rivest S. Mild chronic cerebral hypoperfusion induces neurovascular dysfunction, triggering peripheral beta-amyloid brain entry and aggregation. Acta Neuropathol Commun. 2013;1:75 pubmed 出版商
  • 免疫组化-自由浮动切片; 小鼠; 1:2000
Marchese M, Cowan D, Head E, Ma D, Karimi K, Ashthorpe V, et al. Autoimmune manifestations in the 3xTg-AD model of Alzheimer's disease. J Alzheimers Dis. 2014;39:191-210 pubmed 出版商
  • 免疫沉淀; 小鼠
Bhaskar K, Maphis N, Xu G, Varvel N, Kokiko Cochran O, Weick J, et al. Microglial derived tumor necrosis factor-? drives Alzheimer's disease-related neuronal cell cycle events. Neurobiol Dis. 2014;62:273-85 pubmed 出版商
  • 免疫组化; 小鼠; 1:200
Devi L, Ohno M. Mechanisms that lessen benefits of ?-secretase reduction in a mouse model of Alzheimer's disease. Transl Psychiatry. 2013;3:e284 pubmed 出版商
  • 免疫组化; 人类
Jackson K, Barisone G, Diaz E, Jin L, DeCarli C, Despa F. Amylin deposition in the brain: A second amyloid in Alzheimer disease?. Ann Neurol. 2013;74:517-26 pubmed 出版商
  • 免疫印迹; 人类
Chapuis J, Vingtdeux V, Campagne F, Davies P, Marambaud P. Growth arrest-specific 1 binds to and controls the maturation and processing of the amyloid-beta precursor protein. Hum Mol Genet. 2011;20:2026-36 pubmed 出版商
  • 免疫印迹; 人类
Beyer A, von Einem B, Schwanzar D, Keller I, Hellrung A, Thal D, et al. Engulfment adapter PTB domain containing 1 interacts with and affects processing of the amyloid-? precursor protein. Neurobiol Aging. 2012;33:732-43 pubmed 出版商
Moelgg K, Jummun F, Humpel C. Spreading of Beta-Amyloid in Organotypic Mouse Brain Slices and Microglial Elimination and Effects on Cholinergic Neurons. Biomolecules. 2021;11: pubmed 出版商
Arber C, Lovejoy C, Harris L, Willumsen N, Alatza A, Casey J, et al. Familial Alzheimer's Disease Mutations in PSEN1 Lead to Premature Human Stem Cell Neurogenesis. Cell Rep. 2021;34:108615 pubmed 出版商
Quartey M, Nyarko J, Maley J, Barnes J, Bolanos M, Heistad R, et al. The Aβ(1-38) peptide is a negative regulator of the Aβ(1-42) peptide implicated in Alzheimer disease progression. Sci Rep. 2021;11:431 pubmed 出版商
Su Q, Li T, He P, Lu X, Yu Q, Gao Q, et al. Trichostatin A ameliorates Alzheimer's disease-related pathology and cognitive deficits by increasing albumin expression and Aβ clearance in APP/PS1 mice. Alzheimers Res Ther. 2021;13:7 pubmed 出版商
Dai Y, Han G, Xu S, Yuan Y, Zhao C, Ma T. Echinacoside Suppresses Amyloidogenesis and Modulates F-actin Remodeling by Targeting the ER Stress Sensor PERK in a Mouse Model of Alzheimer's Disease. Front Cell Dev Biol. 2020;8:593659 pubmed 出版商
Shen Y, Hua L, Yeh C, Shen L, Ying M, Zhang Z, et al. Ultrasound with microbubbles improves memory, ameliorates pathology and modulates hippocampal proteomic changes in a triple transgenic mouse model of Alzheimer's disease. Theranostics. 2020;10:11794-11819 pubmed 出版商
Benthem S, Skelin I, Moseley S, Stimmell A, Dixon J, Melilli A, et al. Impaired Hippocampal-Cortical Interactions during Sleep in a Mouse Model of Alzheimer's Disease. Curr Biol. 2020;30:2588-2601.e5 pubmed 出版商
Soto Mercado V, Mendivil Perez M, Velez Pardo C, Lopera F, Jimenez Del Rio M. Cholinergic-like neurons carrying PSEN1 E280A mutation from familial Alzheimer's disease reveal intraneuronal sAPPβ fragments accumulation, hyperphosphorylation of TAU, oxidative stress, apoptosis and Ca2+ dysregulation: Therapeutic implications. PLoS ONE. 2020;15:e0221669 pubmed 出版商
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产品信息
抗原 :
乙淀粉样蛋白1-16
Apps. Abbrev. :
Western Blotting, Direct ELISA, IHC-P, IHC-F, EM
目录 :
803015
克隆 :
6E10
产品 :
Anti-β-Amyloid, 1-16
抗体亚型 :
Mouse IgG1, κ
其他名称 :
AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2, Amyloid beta A4 protein, preA4, protease, peptidase nexin-II, beta-amyloid peptide, alzheimer disease amyloid protein, cerebral vascular amyloid peptide, APP, Amyloid Precursor Protein
规格 :
200微升
价格(美元) :
1054美元
反应物种 :
人类
克隆性 :
单克隆
宿主 :
小鼠
共轭标签/标签/标记 :
腹水
应用注释 :
This antibody is reactive to amino acid residue 1-16 of beta amyloid. The epitope lies within amino acids 3-8 of beta amyloid (EFRHDS). This antibody clone has been reported for use in immunohistochemistry of free-floating sections 2,13 .
更多信息或购买 :
公司信息
BioLegend
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San Diego, CA 92121
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https://www.biolegend.com
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公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品,旨在加速生命科学领域的研发工作。