产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
Purified (azide-free) anti-mouse/rat β-Amyloid, 1-16
目录 :
805701
规格 :
200微升
价格 :
546美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
M3.2
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫细胞化学, 免疫沉淀
更多信息或购买 :
BioLegend 产品网页
文章摘录数: 9
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 大鼠; 1:1000; 图 2b
Tambini M, Norris K, D ADAMIO L. Opposite changes in APP processing and human Aβ levels in rats carrying either a protective or a pathogenic APP mutation. elife. 2020;9: pubmed 出版商
  • 免疫印迹; 小鼠; 图 s2c
Sun J, Carlson Stevermer J, Das U, Shen M, Delenclos M, Snead A, et al. CRISPR/Cas9 editing of APP C-terminus attenuates β-cleavage and promotes α-cleavage. Nat Commun. 2019;10:53 pubmed 出版商
  • 免疫印迹; 大鼠; 1:1000
Lundgren J, Ahmed S, Schedin Weiss S, Gouras G, Winblad B, Tjernberg L, et al. ADAM10 and BACE1 are localized to synaptic vesicles. J Neurochem. 2015;135:606-15 pubmed 出版商
  • 免疫沉淀; 小鼠; 1:300
  • 免疫印迹; 小鼠; 1:800
Corbett G, Gonzalez F, Pahan K. Activation of peroxisome proliferator-activated receptor α stimulates ADAM10-mediated proteolysis of APP. Proc Natl Acad Sci U S A. 2015;112:8445-50 pubmed 出版商
Socodato R, Portugal C, Canedo T, Rodrigues A, Almeida T, Henriques J, et al. Microglia Dysfunction Caused by the Loss of Rhoa Disrupts Neuronal Physiology and Leads to Neurodegeneration. Cell Rep. 2020;31:107796 pubmed 出版商
Gulisano W, Melone M, Ripoli C, Rosaria Tropea M, Li Puma D, Giunta S, et al. Neuromodulatory action of picomolar extracellular Aβ42 oligomers on pre- and postsynaptic mechanisms underlying synaptic function and memory. J Neurosci. 2019;: pubmed 出版商
Wang W, Hou T, Jia L, Wu Q, Quan M, Jia J. Toxic amyloid-β oligomers induced self-replication in astrocytes triggering neuronal injury. EBioMedicine. 2019;42:174-187 pubmed 出版商
Miranda A, Lasiecka Z, Xu Y, Neufeld J, Shahriar S, Simoes S, et al. Neuronal lysosomal dysfunction releases exosomes harboring APP C-terminal fragments and unique lipid signatures. Nat Commun. 2018;9:291 pubmed 出版商
Daria A, Colombo A, Llovera G, Hampel H, Willem M, Liesz A, et al. Young microglia restore amyloid plaque clearance of aged microglia. EMBO J. 2017;36:583-603 pubmed 出版商
产品信息
抗原 :
乙淀粉样蛋白1-16
Apps. Abbrev. :
Western Blotting, ICC, IP, ELISA Detection, ELISA Capture
目录 :
805701
克隆 :
M3.2
产品 :
Purified (azide-free) anti-mouse/rat β-Amyloid, 1-16
抗体亚型 :
Mouse IgG1, κ
其他名称 :
AAA, ABETA, ABPP, AD1, APPI, CTFgamma, CVAP, PN-II, PN2, Amyloid beta A4 protein, preA4, protease, peptidase nexin-II, beta-amyloid peptide, alzheimer disease amyloid protein, cerebral vascular amyloid peptide, APP, Amyloid Precursor Protein
规格 :
200微升
价格(美元) :
546美元
反应物种 :
小鼠, 大鼠
克隆性 :
单克隆
宿主 :
小鼠
共轭标签/标签/标记 :
PUREAF
免疫原 :
The epitope has been determined to be within residues 10-15 of murine Aβ.
应用注释 :
Clone M3.2 recognizes a rodent sequence of A , -CTF, sAPP-a, and full length APP. Clone 3.2 has negligible cross reactivity with human isoforms of APP and beta amyloid.
更多信息或购买 :
BioLegend 产品网页
公司信息
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品，旨在加速生命科学领域的研发工作。