产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
Purified (azide-free) anti-α-Synuclein, 103-108
目录 :
807801
规格 :
200微升
价格 :
528美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
4B12/Synuclein
反应物种 :
人类, 大鼠
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫组化-石蜡切片, 免疫组化-冰冻切片
更多信息或购买 :
文章摘录数: 10
出版应用/物种/样本/稀释参考文献
  • 免疫组化; 人类; 1:300; 图 1c
  • 免疫印迹; 人类; 1:1000; 图 1e
Zhao J, Lu W, Ren Y, Fu Y, Martens Y, Shue F, et al. Apolipoprotein E regulates lipid metabolism and α-synuclein pathology in human iPSC-derived cerebral organoids. Acta Neuropathol. 2021;142:807-825 pubmed 出版商
  • 免疫组化-冰冻切片; 大鼠; 1:1000; 图 1a
  • 免疫印迹; 大鼠; 1:1000; 图 2c
Dimant H, Zhu L, Kibuuka L, Fan Z, Hyman B, McLean P. Direct visualization of CHIP-mediated degradation of alpha-synuclein in vivo: implications for PD therapeutics. PLoS ONE. 2014;9:e92098 pubmed 出版商
Van der Perren A, Gelders G, Fenyi A, Bousset L, Brito F, Peelaerts W, et al. The structural differences between patient-derived α-synuclein strains dictate characteristics of Parkinson's disease, multiple system atrophy and dementia with Lewy bodies. Acta Neuropathol. 2020;139:977-1000 pubmed 出版商
Zhao N, Attrebi O, Ren Y, Qiao W, Sonustun B, Martens Y, et al. APOE4 exacerbates α-synuclein pathology and related toxicity independent of amyloid. Sci Transl Med. 2020;12: pubmed 出版商
Cuddy L, Wani W, Morella M, Pitcairn C, Tsutsumi K, Fredriksen K, et al. Stress-Induced Cellular Clearance Is Mediated by the SNARE Protein ykt6 and Disrupted by α-Synuclein. Neuron. 2019;104:869-884.e11 pubmed 出版商
Cariulo C, Martufi P, Verani M, Azzollini L, Bruni G, Weiss A, et al. Phospho-S129 Alpha-Synuclein Is Present in Human Plasma but Not in Cerebrospinal Fluid as Determined by an Ultrasensitive Immunoassay. Front Neurosci. 2019;13:889 pubmed 出版商
Schaser A, Osterberg V, Dent S, Stackhouse T, Wakeham C, Boutros S, et al. Alpha-synuclein is a DNA binding protein that modulates DNA repair with implications for Lewy body disorders. Sci Rep. 2019;9:10919 pubmed 出版商
Heras Garvín A, Weckbecker D, Ryazanov S, Leonov A, Griesinger C, Giese A, et al. Anle138b modulates α-synuclein oligomerization and prevents motor decline and neurodegeneration in a mouse model of multiple system atrophy. Mov Disord. 2019;34:255-263 pubmed 出版商
Jiang P, Gan M, Yen S, McLean P, Dickson D. Impaired endo-lysosomal membrane integrity accelerates the seeding progression of α-synuclein aggregates. Sci Rep. 2017;7:7690 pubmed 出版商
Phan J, Stokholm K, Zareba Paslawska J, Jakobsen S, Vang K, Gjedde A, et al. Early synaptic dysfunction induced by α-synuclein in a rat model of Parkinson's disease. Sci Rep. 2017;7:6363 pubmed 出版商
产品信息
抗原 :
alpha突触核蛋白103-108
Apps. Abbrev. :
免疫组化-P, 酶联免疫吸附测定, 西方墨点法
目录 :
807801
克隆 :
4B12/Synuclein
产品 :
Purified (azide-free) anti-α-Synuclein, 103-108
抗体亚型 :
Mouse IgG1, κ
其他名称 :
NACP, PARK1, PARK4, PD1, Synuclein alpha-140, non-A4 component of amyloid, alpha-synuclein, isoform NACP140, non-A beta component of AD amyloid Parkinson disease
规格 :
200微升
价格(美元) :
528美元
反应物种 :
人类
克隆性 :
单克隆
宿主 :
小鼠
共轭标签/标签/标记 :
PUREAF
免疫原 :
This antibody was developed using a purified, E. coli produced human α-synuclein.
应用注释 :
This antibody reacts with human a-synuclein. It does not react with mouse or rat a-synuclein. The epitope lies within amino acids 103-108 of a-synuclein. Additional reported applications (for the relevant formats) include: ELISA 2 , Western blotting 1,2,3,4,6,8 , and immunoprecipitation 4 .
更多信息或购买 :
公司信息
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品,旨在加速生命科学领域的研发工作。