产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
纯化(无叠氮物)抗sAPPβ
目录 :
813401
规格 :
50微克
价格 :
654美元
克隆性 :
多克隆
宿主 :
domestic rabbit
共轭标签 :
未共轭
克隆名称 :
Poly8134
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹
更多信息或购买 :
文章摘录数: 16
出版应用/物种/样本/稀释参考文献
  • 免疫印迹; 人类; 图 1r
Wang C, Najm R, Xu Q, Jeong D, Walker D, Balestra M, et al. Gain of toxic apolipoprotein E4 effects in human iPSC-derived neurons is ameliorated by a small-molecule structure corrector. Nat Med. 2018;24:647-657 pubmed 出版商
  • 免疫印迹; 人类; 图 8a
Ruan C, Liu J, Yang M, Saadipour K, Zeng Y, Liao H, et al. Sortilin inhibits amyloid pathology by regulating non-specific degradation of APP. Exp Neurol. 2018;299:75-85 pubmed 出版商
  • 免疫印迹; 小鼠; 1:1000; 图 4d
Griñan Ferré C, Sarroca S, Ivanova A, Puigoriol Illamola D, Aguado F, Camins A, et al. Epigenetic mechanisms underlying cognitive impairment and Alzheimer disease hallmarks in 5XFAD mice. Aging (Albany NY). 2016;8:664-84 pubmed 出版商
Zhong B, Zhou G, Song L, Wen Q, Deng X, Ma Y, et al. TUFM is involved in Alzheimer's disease-like pathologies that are associated with ROS. FASEB J. 2021;35:e21445 pubmed 出版商
Li K, Xiang X, Song L, Chen J, Luo B, Wen Q, et al. Mitochondrial TXN2 attenuates amyloidogenesis via selective inhibition of BACE1 expression. J Neurochem. 2021;157:1351-1365 pubmed 出版商
Tambini M, Norris K, D ADAMIO L. Opposite changes in APP processing and human Aβ levels in rats carrying either a protective or a pathogenic APP mutation. elife. 2020;9: pubmed 出版商
Xiang J, Zhang W, Cai X, Cai M, Yu Z, Yang F, et al. DNA Aptamers Targeting BACE1 Reduce Amyloid Levels and Rescue Neuronal Deficiency in Cultured Cells. Mol Ther Nucleic Acids. 2019;16:302-312 pubmed 出版商
Wang W, Hou T, Jia L, Wu Q, Quan M, Jia J. Toxic amyloid-β oligomers induced self-replication in astrocytes triggering neuronal injury. EBioMedicine. 2019;42:174-187 pubmed 出版商
Tsang J, Lee M, Chan T, Li J, Ni Y, Shao Y, et al. Proteolytic cleavage of amyloid precursor protein by ADAM10 mediates proliferation and migration in breast cancer. EBioMedicine. 2018;38:89-99 pubmed 出版商
Marwarha G, Schommer J, Lund J, Schommer T, Ghribi O. Palmitate-induced C/EBP homologous protein activation leads to NF-κB-mediated increase in BACE1 activity and amyloid beta genesis. J Neurochem. 2018;144:761-779 pubmed 出版商
Jean Louis T, Rockwell P, Figueiredo Pereira M. Prostaglandin J2 promotes O-GlcNAcylation raising APP processing by α- and β-secretases: relevance to Alzheimer's disease. Neurobiol Aging. 2018;62:130-145 pubmed 出版商
Kotfis K, Zegan Barańska M, Szydłowski Ł, Zukowski M, Ely E. Methods of pain assessment in adult intensive care unit patients - Polish version of the CPOT (Critical Care Pain Observation Tool) and BPS (Behavioral Pain Scale). Anaesthesiol Intensive Ther. 2017;49:66-72 pubmed 出版商
Qin X, Wang Y, Paudel H. Early Growth Response 1 (Egr-1) Is a Transcriptional Activator of ?-Secretase 1 (BACE-1) in the Brain. J Biol Chem. 2016;291:22276-22287 pubmed
Salta E, Sierksma A, Vanden Eynden E, De Strooper B. miR-132 loss de-represses ITPKB and aggravates amyloid and TAU pathology in Alzheimer's brain. EMBO Mol Med. 2016;8:1005-18 pubmed 出版商
Rabinovich Toidman P, Rabinovich Nikitin I, Ezra A, Barbiro B, Fogel H, Slutsky I, et al. Mutant SOD1 Increases APP Expression and Phosphorylation in Cellular and Animal Models of ALS. PLoS ONE. 2015;10:e0143420 pubmed 出版商
Corbett G, Gonzalez F, Pahan K. Activation of peroxisome proliferator-activated receptor α stimulates ADAM10-mediated proteolysis of APP. Proc Natl Acad Sci U S A. 2015;112:8445-50 pubmed 出版商
产品信息
抗原 :
sAPPbeta
Apps. Abbrev. :
西方墨点法
目录 :
813401
克隆 :
Poly8134
产品 :
纯化(无叠氮物)抗sAPPβ
抗体亚型 :
兔多克隆IgG
其他名称 :
Amyloid beta A4 protein, preA4, protease nexin-II, peptidase nexin-II, beta-amyloid peptide, alzheimer disease amyloid protein, cerebral vascular amyloid peptide, APP, Amyloid Precursor Protein
规格 :
50微克
价格(美元) :
654美元
反应物种 :
人类, 小鼠, 大鼠
克隆性 :
多克隆
宿主 :
共轭标签/标签/标记 :
PUREAF
应用注释 :
This antibody is specific for the soluble fragment cleaved n-terminus to the beta secretase cleavage site of amyloid precursor protein. It has neglible cross reactivity to sAPPa or full length APP. This product may contain other non-IgG subtypes.
更多信息或购买 :
公司信息
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品,旨在加速生命科学领域的研发工作。