出版应用/物种/样本/稀释 | 参考文献 |
---|
| Zunke F, Moise A, Belur N, Gelyana E, Stojkovska I, Dzaferbegovic H, et al. Reversible Conformational Conversion of α-Synuclein into Toxic Assemblies by Glucosylceramide. Neuron. 2018;97:92-107.e10 pubmed 出版商
|
| Mazzulli J, Zunke F, Tsunemi T, Toker N, Jeon S, Burbulla L, et al. Activation of β-Glucocerebrosidase Reduces Pathological α-Synuclein and Restores Lysosomal Function in Parkinson's Patient Midbrain Neurons. J Neurosci. 2016;36:7693-706 pubmed 出版商
|
| Macdonald J, Chen J, Masuda Suzukake M, Schweighauser M, Jaunmuktane Z, Warner T, et al. Assembly of α-synuclein and neurodegeneration in the central nervous system of heterozygous M83 mice following the peripheral administration of α-synuclein seeds. Acta Neuropathol Commun. 2021;9:189 pubmed 出版商
|
| Kahriman A, Bouley J, Smith T, Bosco D, Woerman A, Henninger N. Mouse closed head traumatic brain injury replicates the histological tau pathology pattern of human disease: characterization of a novel model and systematic review of the literature. Acta Neuropathol Commun. 2021;9:118 pubmed 出版商
|
| Stojkovska I, Mazzulli J. Detection of pathological alpha-synuclein aggregates in human iPSC-derived neurons and tissue. STAR Protoc. 2021;2:100372 pubmed 出版商
|
| Klingstedt T, Ghetti B, Holton J, Ling H, Nilsson K, Goedert M. Luminescent conjugated oligothiophenes distinguish between α-synuclein assemblies of Parkinson's disease and multiple system atrophy. Acta Neuropathol Commun. 2019;7:193 pubmed 出版商
|
| Abd Elhadi S, Grigoletto J, Poli M, Arosio P, Arkadir D, Sharon R. α-Synuclein in blood cells differentiates Parkinson's disease from healthy controls. Ann Clin Transl Neurol. 2019;6:2426-2436 pubmed 出版商
|
| Cuddy L, Wani W, Morella M, Pitcairn C, Tsutsumi K, Fredriksen K, et al. Stress-Induced Cellular Clearance Is Mediated by the SNARE Protein ykt6 and Disrupted by α-Synuclein. Neuron. 2019;104:869-884.e11 pubmed 出版商
|
| Nicot S, Verchère J, Belondrade M, Mayran C, Betemps D, Bougard D, et al. Seeded propagation of α-synuclein aggregation in mouse brain using protein misfolding cyclic amplification. FASEB J. 2019;33:12073-12086 pubmed 出版商
|
| Li X, Koudstaal W, Fletcher L, Costa M, Van Winsen M, Siregar B, et al. Naturally occurring antibodies isolated from PD patients inhibit synuclein seeding in vitro and recognize Lewy pathology. Acta Neuropathol. 2019;137:825-836 pubmed 出版商
|
| Sargent D, Verchère J, Lazizzera C, Gaillard D, Lakhdar L, Streichenberger N, et al. 'Prion-like' propagation of the synucleinopathy of M83 transgenic mice depends on the mouse genotype and type of inoculum. J Neurochem. 2017;143:126-135 pubmed 出版商
|
| Covell D, Robinson J, Akhtar R, Grossman M, Weintraub D, Bucklin H, et al. Novel conformation-selective alpha-synuclein antibodies raised against different in vitro fibril forms show distinct patterns of Lewy pathology in Parkinson's disease. Neuropathol Appl Neurobiol. 2017;43:604-620 pubmed 出版商
|
| Tran H, Chung C, Iba M, Zhang B, Trojanowski J, Luk K, et al. ?-synuclein immunotherapy blocks uptake and templated propagation of misfolded ?-synuclein and neurodegeneration. Cell Rep. 2014;7:2054-65 pubmed 出版商
|
| Colla E, Jensen P, Pletnikova O, Troncoso J, Glabe C, Lee M. Accumulation of toxic ?-synuclein oligomer within endoplasmic reticulum occurs in ?-synucleinopathy in vivo. J Neurosci. 2012;32:3301-5 pubmed 出版商
|
| Tsika E, Moysidou M, Guo J, Cushman M, Gannon P, Sandaltzopoulos R, et al. Distinct region-specific alpha-synuclein oligomers in A53T transgenic mice: implications for neurodegeneration. J Neurosci. 2010;30:3409-18 pubmed 出版商
|
| Luk K, Song C, O BRIEN P, Stieber A, Branch J, Brunden K, et al. Exogenous alpha-synuclein fibrils seed the formation of Lewy body-like intracellular inclusions in cultured cells. Proc Natl Acad Sci U S A. 2009;106:20051-6 pubmed 出版商
|
| Soper J, Roy S, Stieber A, Lee E, Wilson R, Trojanowski J, et al. Alpha-synuclein-induced aggregation of cytoplasmic vesicles in Saccharomyces cerevisiae. Mol Biol Cell. 2008;19:1093-103 pubmed 出版商
|
| Fan Y, Limprasert P, Murray I, Smith A, Lee V, Trojanowski J, et al. Beta-synuclein modulates alpha-synuclein neurotoxicity by reducing alpha-synuclein protein expression. Hum Mol Genet. 2006;15:3002-11 pubmed
|
| Wilson C, Murphy D, Giasson B, Zhang B, Trojanowski J, Lee V. Degradative organelles containing mislocalized alpha-and beta-synuclein proliferate in presenilin-1 null neurons. J Cell Biol. 2004;165:335-46 pubmed
|
| Uryu K, Giasson B, Longhi L, Martinez D, Murray I, Conte V, et al. Age-dependent synuclein pathology following traumatic brain injury in mice. Exp Neurol. 2003;184:214-24 pubmed
|
| Neumann M, Kahle P, Giasson B, Ozmen L, Borroni E, Spooren W, et al. Misfolded proteinase K-resistant hyperphosphorylated alpha-synuclein in aged transgenic mice with locomotor deterioration and in human alpha-synucleinopathies. J Clin Invest. 2002;110:1429-39 pubmed
|
| Giasson B, Duda J, Quinn S, Zhang B, Trojanowski J, Lee V. Neuronal alpha-synucleinopathy with severe movement disorder in mice expressing A53T human alpha-synuclein. Neuron. 2002;34:521-33 pubmed
|