产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
Purified anti-β-Amyloid, 1-11
目录 :
835104
规格 :
100微克
价格 :
235美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
未共轭
克隆名称 :
NAB 228
反应物种 :
人类
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫沉淀, 免疫组化-石蜡切片
更多信息或购买 :
文章摘录数: 10
参考文献
Hagan N, Kane J, Grover D, Woodworth L, Madore C, Saleh J, et al. CSF1R signaling is a regulator of pathogenesis in progressive MS. Cell Death Dis. 2020;11:904 pubmed 出版商
Mandler M, Santic R, Gruber P, Cinar Y, Pichler D, Funke S, et al. Tailoring the antibody response to aggregated Aß using novel Alzheimer-vaccines. PLoS ONE. 2015;10:e0115237 pubmed 出版商
Robinson J, Molina Porcel L, Corrada M, Raible K, Lee E, Lee V, et al. Perforant path synaptic loss correlates with cognitive impairment and Alzheimer's disease in the oldest-old. Brain. 2014;137:2578-87 pubmed 出版商
Berlau D, Corrada M, Robinson J, Geser F, Arnold S, Lee V, et al. Neocortical β-amyloid area is associated with dementia and APOE in the oldest-old. Alzheimers Dement. 2013;9:699-705 pubmed 出版商
Carroll J, Iba M, Bangasser D, Valentino R, James M, Brunden K, et al. Chronic stress exacerbates tau pathology, neurodegeneration, and cognitive performance through a corticotropin-releasing factor receptor-dependent mechanism in a transgenic mouse model of tauopathy. J Neurosci. 2011;31:14436-49 pubmed 出版商
Wolk D, Grachev I, Buckley C, Kazi H, Grady M, Trojanowski J, et al. Association between in vivo fluorine 18-labeled flutemetamol amyloid positron emission tomography imaging and in vivo cerebral cortical histopathology. Arch Neurol. 2011;68:1398-403 pubmed 出版商
Hurtado D, Molina Porcel L, Iba M, Aboagye A, Paul S, Trojanowski J, et al. A{beta} accelerates the spatiotemporal progression of tau pathology and augments tau amyloidosis in an Alzheimer mouse model. Am J Pathol. 2010;177:1977-88 pubmed 出版商
Lee E, Leng L, Zhang B, Kwong L, Trojanowski J, Abel T, et al. Targeting amyloid-beta peptide (Abeta) oligomers by passive immunization with a conformation-selective monoclonal antibody improves learning and memory in Abeta precursor protein (APP) transgenic mice. J Biol Chem. 2006;281:4292-9 pubmed
Lee E, Zhang B, Liu K, Greenbaum E, Doms R, Trojanowski J, et al. BACE overexpression alters the subcellular processing of APP and inhibits Abeta deposition in vivo. J Cell Biol. 2005;168:291-302 pubmed
Lee E, Skovronsky D, Abtahian F, Doms R, Lee V. Secretion and intracellular generation of truncated Abeta in beta-site amyloid-beta precursor protein-cleaving enzyme expressing human neurons. J Biol Chem. 2003;278:4458-66 pubmed
产品信息
抗原 :
乙淀粉样蛋白1-11
Apps. Abbrev. :
IHC-P, ELISA Detection, IP, Western Blotting
目录 :
835104
克隆 :
NAB 228
产品 :
Purified anti-β-Amyloid, 1-11
抗体亚型 :
Mouse IgG2a, κ
其他名称 :
Amyloid beta A4 protein, preA4, protease nexin-II, peptidase nexin-II, beta-amyloid peptide, alzheimer disease amyloid protein, cerebral vascular amyloid peptide, APP, Amyloid Precursor Protein
规格 :
100微克
价格(美元) :
235美元
反应物种 :
人类
克隆性 :
单克隆
宿主 :
小鼠
共轭标签/标签/标记 :
PURE
免疫原 :
This antibody was raised against a peptide sequence corresponding to amino acids 1-11 of human amyloid beta (Aβ) protein.
应用注释 :
Additional reported applications (for the releavant formats) include immunoprecipication 4 , Western blotting 1,2,4,9 , and immunoflurescence microscopy 7 . NAB 228 recognizes a peptide corresponding to amino acid residues 1-11 of the human amyloid beta (Aß) as determined by ELISA using peptides that block its immunoreactivity. This antibody also recognizes full length amyloid precursor protein (APP), soluble APP form (sAPPa), C99 cleavage form, and Aß (1-40 and 1-42). NAP 228 does not recognize sAPPß. This antibody can be used to stain amyloid plaques (diffuse and compact) and amyloid angiopathy on formalin-fixed paraffin-embedded tissue (human AD, Downs syndrome, MCI and transgenic mouse).
更多信息或购买 :
公司信息
BioLegend
8999 BioLegend Way
San Diego, CA 92121
customerserv@biolegend.com
https://www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品,旨在加速生命科学领域的研发工作。