产品简要
公司名称 :
BioLegend
其他品牌 :
Babco, Signet, Sternberger Monoclonals, Senetek, Covance
产品类型 :
抗体
产品名称 :
Anti-GFAP (Cocktail)
目录 :
837602
规格 :
500微升
价格 :
411美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
nonconjugated
克隆名称 :
SMI 26
反应物种 :
人类, 小鼠, 大鼠, , ,
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫组化, 免疫细胞化学
更多信息或购买 :
文章摘录数: 2
出版应用/物种/样品/稀释参考文献
  • 免疫组化; 小鼠; 1:1000; 图 1
Heaven M, Flint D, Randall S, Sosunov A, Wilson L, Barnes S, et al. Composition of Rosenthal Fibers, the Protein Aggregate Hallmark of Alexander Disease. J Proteome Res. 2016;15:2265-82 pubmed 出版商
Chen M, Hagemann T, Quinlan R, Messing A, Perng M. Caspase cleavage of GFAP produces an assembly-compromised proteolytic fragment that promotes filament aggregation. ASN Neuro. 2013;5:e00125 pubmed 出版商
产品信息
抗原 :
GFAP
Apps. Abbrev. :
免疫组化, 西方墨点法, 免疫细胞化学, 酶联免疫吸附测定
目录 :
837602
克隆 :
SMI 26
产品 :
Anti-GFAP (Cocktail)
抗体亚型 :
小鼠IgG1/小鼠IgG2b
其他名称 :
胶质纤维酸性蛋白, SMI-26R-500
规格 :
500微升
价格(美元) :
411美元
反应物种 :
人类, 羊, 牛, 狗, 猪, 大鼠, 豚鼠, 大鼠, 小鼠, 鸡
克隆性 :
单克隆
宿主 :
小鼠
共轭标签/标签/标记 :
腹水
应用注释 :
This antibody cocktail is effective in immunoblotting, immunocytochemistry, immunohistochemistry and ELISA. The Bigner-Eng antibodies have originally been assayed by indirect radioimmunoassay against fixed cell monolayers of a GFAP-positive human glioma cell line and also by competitive radioimmunoassay with radiolabelled GFAP and by competitive immunoradioassay with radiolabelled antibody. They have been further characterized by immunoblots of GFAP and by immunocytochemistry. Each of the Bigner-Eng antibodies is specific for GFAP and visualizes immunocytochemically astrocytes and astrocytic processes as well as Bergman glia in a wide variety of species. Mixtures of the three Bigner-Eng antibodies provide for a more comprehensive detection of astrocytomas than each antibody alone. Both, anaplastic and reactive astrocytes are stained immunocytochemically. Metastatic tumors and brain tumors of non-astrocytic origin, such as medulloblastomas, meningiomas, choroid plexus papillomas and schwannomas are not stained. There appears to be a positive correlation between fibrillarity of immunocytochemical localization in astrocytomas and their degrees of differentiation, and a negative correlation between the percentage of positive cells and their degree of anaplasticity. In morphologically diagnosed ependymomas and oligodendrogliomas positive reaction appears to reveal presence of malignant astrocytes. SMI 26 is a cocktail of GFAP antibodies SMI 21 (mouse monoclonal IgG1) and SMI 23, SMI 24, and SMI 25 (all mouse monoclonal IgG2b) for a comprehensive visualization of astrocytomas.
更多信息或购买 :
公司信息
BioLegend
9727 Pacific Heights Blvd.
San Diego, CA 92121
customerserv@biolegend.com
www.biolegend.com
1-858-455-9588
公司总部: 美国
Biolegend公司为生物医学研究提供顶级的抗体及试剂产品,旨在加速生命科学领域的研发工作。