| 出版应用/物种/样本/稀释 | 参考文献 |
|---|
- 免疫组化-石蜡切片; 人类; 1:300; 图 3c
- 免疫组化-石蜡切片; 小鼠; 1:300; 图 4c
| Rhinn M, Zapata Bodalo I, Klein A, Plassat J, Knauer Meyer T, Keyes W. Aberrant induction of p19Arf-mediated cellular senescence contributes to neurodevelopmental defects. PLoS Biol. 2022;20:e3001664 pubmed 出版商 |
| Bashford A, Subramanian V. Hippocampals neurogenesis is impaired in mice with a deletion in the coiled coil domain of Talpid3-implications for Joubert syndrome. Hum Mol Genet. 2022;31:3245-3265 pubmed 出版商 |
- 免疫组化-冰冻切片; 人类; 1:200-1:2000; 图 s8d
- 免疫组化-冰冻切片; African green monkey; 1:200-1:2000; 图 1a
- 免疫组化-冰冻切片; 小鼠; 1:200-1:2000; 图 1c
| Zhu X, Guo Y, Chu C, Liu D, Duan K, Yin Y, et al. BRN2 as a key gene drives the early primate telencephalon development. Sci Adv. 2022;8:eabl7263 pubmed 出版商 |
| Sapir G, Steinberg D, Aqeilan R, Katz Brull R. Real-Time Non-Invasive and Direct Determination of Lactate Dehydrogenase Activity in Cerebral Organoids-A New Method to Characterize the Metabolism of Brain Organoids?. Pharmaceuticals (Basel). 2021;14: pubmed 出版商 |
| Walker H, Taiyab A, Deschamps P, Williams T, West Mays J. Conditional Deletion of AP-2β in the Periocular Mesenchyme of Mice Alters Corneal Epithelial Cell Fate and Stratification. Int J Mol Sci. 2021;22: pubmed 出版商 |
| Viais R, Fariña Mosquera M, Villamor Payà M, Watanabe S, Palenzuela L, Lacasa C, et al. Augmin deficiency in neural stem cells causes p53-dependent apoptosis and aborts brain development. elife. 2021;10: pubmed 出版商 |
- 免疫组化-冰冻切片; 人类; 1:500; 图 2i
| Cho A, Jin Y, An Y, Kim J, Choi Y, Lee J, et al. Microfluidic device with brain extracellular matrix promotes structural and functional maturation of human brain organoids. Nat Commun. 2021;12:4730 pubmed 出版商 |
| Eriksen A, Møller R, Makovoz B, Uhl S, tenOever B, Blenkinsop T. SARS-CoV-2 infects human adult donor eyes and hESC-derived ocular epithelium. Cell Stem Cell. 2021;28:1205-1220.e7 pubmed 出版商 |
- 免疫组化-冰冻切片; 小鼠; 1:2000; 图 s1c
- 免疫细胞化学; 小鼠; 图 1g
| Nasu M, Esumi S, Hatakeyama J, Tamamaki N, Shimamura K. Two-Phase Lineage Specification of Telencephalon Progenitors Generated From Mouse Embryonic Stem Cells. Front Cell Dev Biol. 2021;9:632381 pubmed 出版商 |
| Ezan J, Moreau M, Mamo T, Shimbo M, Decroo M, Richter M, et al. Early loss of Scribble affects cortical development, interhemispheric connectivity and psychomotor activity. Sci Rep. 2021;11:9106 pubmed 出版商 |
| Inak G, Rybak Wolf A, Lisowski P, Pentimalli T, Jüttner R, Glažar P, et al. Defective metabolic programming impairs early neuronal morphogenesis in neural cultures and an organoid model of Leigh syndrome. Nat Commun. 2021;12:1929 pubmed 出版商 |
| Salas A, Duarri A, Fontrodona L, Ram xed rez D, Badia A, Isla Magran xe9 H, et al. Cell therapy with hiPSC-derived RPE cells and RPCs prevents visual function loss in a rat model of retinal degeneration. Mol Ther Methods Clin Dev. 2021;20:688-702 pubmed 出版商 |
- 免疫组化基因敲除验证; 鸡; 1:250; 图 7d
| Gandhi S, Li Y, Tang W, Christensen J, Urrutia H, Vieceli F, et al. A single-plasmid approach for genome editing coupled with long-term lineage analysis in chick embryos. Development. 2021;148: pubmed 出版商 |
- 免疫组化-冰冻切片; 人类; 1:500; 图 s1a
| Andrews M, Mukhtar T, Eze U, Simoneau C, Perez Y, Mostajo Radji M, et al. Tropism of SARS-CoV-2 for Developing Human Cortical Astrocytes. bioRxiv. 2021;: pubmed 出版商 |
- 免疫组化-石蜡切片; 小鼠; 1:300; 图 6a
| Sheng J, Wang L, Tang P, Wang H, Li J, Xu B, et al. Smad3 deficiency promotes beta cell proliferation and function in db/db mice via restoring Pax6 expression. Theranostics. 2021;11:2845-2859 pubmed 出版商 |
| Arber C, Lovejoy C, Harris L, Willumsen N, Alatza A, Casey J, et al. Familial Alzheimer's Disease Mutations in PSEN1 Lead to Premature Human Stem Cell Neurogenesis. Cell Rep. 2021;34:108615 pubmed 出版商 |
| Cuevas E, Holder D, Alshehri A, Tr xe9 guier J, Lakowski J, Sowden J. NRL-/- gene edited human embryonic stem cells generate rod-deficient retinal organoids enriched in S-cone-like photoreceptors. Stem Cells. 2021;39:414-428 pubmed 出版商 |
| Atkins A, Xu M, Li M, Rogers N, Pryzhkova M, Jordan P. SMC5/6 is required for replication fork stability and faithful chromosome segregation during neurogenesis. elife. 2020;9: pubmed 出版商 |
- 免疫印迹; 人类; 1:5000; 图 1d
- 免疫印迹; 小鼠; 1:5000; 图 1d
| Kim K, Wu Y, Yoon J, Adachi K, Wu G, Velychko S, et al. Reprogramming competence of OCT factors is determined by transactivation domains. Sci Adv. 2020;6: pubmed 出版商 |
- 免疫组化-冰冻切片; 小鼠; 1:400; 图 1a
| Hasenpusch Theil K, Laclef C, Colligan M, Fitzgerald E, Howe K, Carroll E, et al. A transient role of the ciliary gene Inpp5e in controlling direct versus indirect neurogenesis in cortical development. elife. 2020;9: pubmed 出版商 |
- 免疫组化-冰冻切片; 小鼠; 1:500; 图 3b
- 免疫细胞化学; 小鼠; 1:500; 图 s1e
| Mukhtar T, Breda J, Grison A, Karimaddini Z, Grobecker P, Iber D, et al. Tead transcription factors differentially regulate cortical development. Sci Rep. 2020;10:4625 pubmed 出版商 |
| Matsumura K, Seiriki K, Okada S, Nagase M, Ayabe S, Yamada I, et al. Pathogenic POGZ mutation causes impaired cortical development and reversible autism-like phenotypes. Nat Commun. 2020;11:859 pubmed 出版商 |
- 免疫组化-石蜡切片; 人类; 1:700; 图 3f
| Devlin L, Ramsbottom S, Overman L, Lisgo S, Clowry G, Molinari E, et al. Embryonic and foetal expression patterns of the ciliopathy gene CEP164. PLoS ONE. 2020;15:e0221914 pubmed 出版商 |
| Kielkowski P, Buchsbaum I, Kirsch V, Bach N, Drukker M, Cappello S, et al. FICD activity and AMPylation remodelling modulate human neurogenesis. Nat Commun. 2020;11:517 pubmed 出版商 |
- 免疫组化; 小鼠; 1:250; 图 1s2b1b
| S nchez Guardado L, Lois C. Lineage does not regulate the sensory synaptic input of projection neurons in the mouse olfactory bulb. elife. 2019;8: pubmed 出版商 |
| Jin J, Ravindran P, Di Meo D, Püschel A. Igf1R/InsR function is required for axon extension and corpus callosum formation. PLoS ONE. 2019;14:e0219362 pubmed 出版商 |
- 免疫组化-冰冻切片; 人类; 1:400; 图 ex2b
| Velasco S, Kedaigle A, Simmons S, Nash A, Rocha M, Quadrato G, et al. Individual brain organoids reproducibly form cell diversity of the human cerebral cortex. Nature. 2019;: pubmed 出版商 |
- 免疫组化; African green monkey; 1:500; 图 s1b
| Pollen A, Bhaduri A, Andrews M, Nowakowski T, Meyerson O, Mostajo Radji M, et al. Establishing Cerebral Organoids as Models of Human-Specific Brain Evolution. Cell. 2019;176:743-756.e17 pubmed 出版商 |
| Real R, Peter M, Trabalza A, Khan S, Smith M, Dopp J, et al. In vivo modeling of human neuron dynamics and Down syndrome. Science. 2018;362: pubmed 出版商 |
- 免疫组化-冰冻切片; 小鼠; 1:500; 图 2a
| Han S, Dennis D, Balakrishnan A, Dixit R, Britz O, Zinyk D, et al. A non-canonical role for the proneural gene Neurog1 as a negative regulator of neocortical neurogenesis. Development. 2018;145: pubmed 出版商 |
- 免疫组化-冰冻切片; 小鼠; 1:200; 图 s6a
| Segarra M, Aburto M, Cop F, Llaó Cid C, Härtl R, Damm M, et al. Endothelial Dab1 signaling orchestrates neuro-glia-vessel communication in the central nervous system. Science. 2018;361: pubmed 出版商 |
| Klein T, Günther K, Kwok C, Edenhofer F, Uceyler N. Generation of the human induced pluripotent stem cell line (UKWNLi001-A) from skin fibroblasts of a woman with Fabry disease carrying the X-chromosomal heterozygous c.708 G > C (W236C) missense mutation in exon 5 of the alpha-galactosidase-A gene. Stem Cell Res. 2018;31:222-226 pubmed 出版商 |
| Luisier R, Tyzack G, Hall C, Mitchell J, Devine H, Taha D, et al. Intron retention and nuclear loss of SFPQ are molecular hallmarks of ALS. Nat Commun. 2018;9:2010 pubmed 出版商 |
| Zhu F, Zhu Q, Ye D, Zhang Q, Yang Y, Guo X, et al. Sin3a-Tet1 interaction activates gene transcription and is required for embryonic stem cell pluripotency. Nucleic Acids Res. 2018;46:6026-6040 pubmed 出版商 |
- 免疫组化-石蜡切片; 小鼠; 1:500; 图 2g
| Connell M, Chen H, Jiang J, Kuan C, Fotovati A, Chu T, et al. HMMR acts in the PLK1-dependent spindle positioning pathway and supports neural development. elife. 2017;6: pubmed 出版商 |
| Nakagawa N, Li J, Yabuno Nakagawa K, Eom T, Cowles M, Mapp T, et al. APC sets the Wnt tone necessary for cerebral cortical progenitor development. Genes Dev. 2017;31:1679-1692 pubmed 出版商 |
| Tchieu J, Zimmer B, Fattahi F, Amin S, Zeltner N, Chen S, et al. A Modular Platform for Differentiation of Human PSCs into All Major Ectodermal Lineages. Cell Stem Cell. 2017;21:399-410.e7 pubmed 出版商 |
| Hatakeyama J, Sato H, Shimamura K. Developing guinea pig brain as a model for cortical folding. Dev Growth Differ. 2017;59:286-301 pubmed 出版商 |
| del Toro D, Ruff T, Cederfjäll E, Villalba A, Seyit Bremer G, Borrell V, et al. Regulation of Cerebral Cortex Folding by Controlling Neuronal Migration via FLRT Adhesion Molecules. Cell. 2017;169:621-635.e16 pubmed 出版商 |
- 免疫组化-冰冻切片; 人类; 1:400
- 免疫细胞化学; 人类; 1:400; 图 e1b
| Quadrato G, Nguyen T, Macosko E, Sherwood J, Min Yang S, Berger D, et al. Cell diversity and network dynamics in photosensitive human brain organoids. Nature. 2017;545:48-53 pubmed 出版商 |
- 免疫组化-石蜡切片; 小鼠; 1:500; 图 1b
| Feng W, Kawauchi D, Körkel Qu H, Deng H, Serger E, Sieber L, et al. Chd7 is indispensable for mammalian brain development through activation of a neuronal differentiation programme. Nat Commun. 2017;8:14758 pubmed 出版商 |
| Choudhary P, Booth H, Gutteridge A, Surmacz B, Louca I, Steer J, et al. Directing Differentiation of Pluripotent Stem Cells Toward Retinal Pigment Epithelium Lineage. Stem Cells Transl Med. 2017;6:490-501 pubmed 出版商 |
- 免疫组化-冰冻切片; 小鼠; 1:200; 图 7e
| Zhang Y, Zeng S, Hao Q, Lu H. Monitoring p53 by MDM2 and MDMX is required for endocrine pancreas development and function in a spatio-temporal manner. Dev Biol. 2017;423:34-45 pubmed 出版商 |
| Qi Y, Zhang X, Renier N, Wu Z, Atkin T, Sun Z, et al. Combined small-molecule inhibition accelerates the derivation of functional cortical neurons from human pluripotent stem cells. Nat Biotechnol. 2017;35:154-163 pubmed 出版商 |
| Bershteyn M, Nowakowski T, Pollen A, Di Lullo E, Nene A, Wynshaw Boris A, et al. Human iPSC-Derived Cerebral Organoids Model Cellular Features of Lissencephaly and Reveal Prolonged Mitosis of Outer Radial Glia. Cell Stem Cell. 2017;20:435-449.e4 pubmed 出版商 |
- 免疫组化-冰冻切片; 小鼠; 1:400; 图 6a
| Bosch P, Fuller L, Sleeth C, Weiner J. Akirin2 is essential for the formation of the cerebral cortex. Neural Dev. 2016;11:21 pubmed |
- 免疫组化-石蜡切片; 小鼠; 1:200; 图 s1
| Lajko M, Cardona H, Taylor J, Shah R, Farrow K, Fawzi A. Hyperoxia-Induced Proliferative Retinopathy: Early Interruption of Retinal Vascular Development with Severe and Irreversible Neurovascular Disruption. PLoS ONE. 2016;11:e0166886 pubmed 出版商 |
| Bassett E, Tokarew N, Allemano E, Mazerolle C, Morin K, Mears A, et al. Norrin/Frizzled4 signalling in the preneoplastic niche blocks medulloblastoma initiation. elife. 2016;5: pubmed 出版商 |
| Zhu L, Gómez Durán A, Saretzki G, Jin S, Tilgner K, Melguizo Sanchís D, et al. The mitochondrial protein CHCHD2 primes the differentiation potential of human induced pluripotent stem cells to neuroectodermal lineages. J Cell Biol. 2016;215:187-202 pubmed |
| Broix L, Jagline H, Ivanova E, Schmucker S, Drouot N, Clayton Smith J, et al. Mutations in the HECT domain of NEDD4L lead to AKT-mTOR pathway deregulation and cause periventricular nodular heterotopia. Nat Genet. 2016;48:1349-1358 pubmed 出版商 |
| Hickmott J, Chen C, Arenillas D, Korecki A, Lam S, Molday L, et al. PAX6 MiniPromoters drive restricted expression from rAAV in the adult mouse retina. Mol Ther Methods Clin Dev. 2016;3:16051 pubmed 出版商 |
| Olsen J, Wong L, Deimling S, Miles A, Guo H, Li Y, et al. G9a and ZNF644 Physically Associate to Suppress Progenitor Gene Expression during Neurogenesis. Stem Cell Reports. 2016;7:454-470 pubmed 出版商 |
- 免疫组化-冰冻切片; 小鼠; 1:1000; 图 3
| Ju X, Hou Q, Sheng A, Wu K, Zhou Y, Jin Y, et al. The hominoid-specific gene TBC1D3 promotes generation of basal neural progenitors and induces cortical folding in mice. elife. 2016;5: pubmed 出版商 |
| Sun Y, Paşca S, Portmann T, Goold C, Worringer K, Guan W, et al. A deleterious Nav1.1 mutation selectively impairs telencephalic inhibitory neurons derived from Dravet Syndrome patients. elife. 2016;5: pubmed 出版商 |
- 免疫组化-冰冻切片; black ferret; 图 1
| Toda T, Shinmyo Y, Dinh Duong T, Masuda K, Kawasaki H. An essential role of SVZ progenitors in cortical folding in gyrencephalic mammals. Sci Rep. 2016;6:29578 pubmed 出版商 |
- 免疫组化-自由浮动切片; 人类; 1:300; 图 4
| Wu J, Hussaini S, Bastille I, Rodriguez G, Mrejeru A, Rilett K, et al. Neuronal activity enhances tau propagation and tau pathology in vivo. Nat Neurosci. 2016;19:1085-92 pubmed 出版商 |
- 免疫组化-冰冻切片; 小鼠; 1:500; 图 2a
- 免疫组化-冰冻切片; 人类; 1:500; 图 s3b
| Wang L, Hou S, Han Y. Hedgehog signaling promotes basal progenitor expansion and the growth and folding of the neocortex. Nat Neurosci. 2016;19:888-96 pubmed 出版商 |
| Douvaras P, Rusielewicz T, Kim K, Haines J, CASACCIA P, Fossati V. Epigenetic Modulation of Human Induced Pluripotent Stem Cell Differentiation to Oligodendrocytes. Int J Mol Sci. 2016;17: pubmed 出版商 |
| Taverna E, Mora Bermúdez F, Strzyz P, Florio M, Icha J, Haffner C, et al. Non-canonical features of the Golgi apparatus in bipolar epithelial neural stem cells. Sci Rep. 2016;6:21206 pubmed 出版商 |
- 免疫组化-冰冻切片; Japanese common newt; 1:1000; 图 2
| Inami W, Islam M, Nakamura K, Yoshikawa T, Yasumuro H, Casco Robles M, et al. Expression of Two Classes of Pax6 Transcripts in Reprogramming Retinal Pigment Epithelium Cells of the Adult Newt. Zoolog Sci. 2016;33:21-30 pubmed 出版商 |
| Wu Z, Li D, Huang Y, Chen X, Huang W, Liu C, et al. Caspr Controls the Temporal Specification of Neural Progenitor Cells through Notch Signaling in the Developing Mouse Cerebral Cortex. Cereb Cortex. 2017;27:1369-1385 pubmed 出版商 |
| Thomsen E, Mich J, Yao Z, Hodge R, Doyle A, Jang S, et al. Fixed single-cell transcriptomic characterization of human radial glial diversity. Nat Methods. 2016;13:87-93 pubmed 出版商 |
| Small K, DeLuca A, Whitmore S, Rosenberg T, Silva Garcia R, Udar N, et al. North Carolina Macular Dystrophy Is Caused by Dysregulation of the Retinal Transcription Factor PRDM13. Ophthalmology. 2016;123:9-18 pubmed 出版商 |
| Radonjić N, Memi F, Ortega J, Glidden N, Zhan H, Zecevic N. The Role of Sonic Hedgehog in the Specification of Human Cortical Progenitors In Vitro. Cereb Cortex. 2016;26:131-43 pubmed 出版商 |
| Vajhøj C, Schmid B, Alik A, Melki R, Fog K, Holst B, et al. Establishment of a human induced pluripotent stem cell neuronal model for identification of modulators of A53T α-synuclein levels and aggregation. PLoS ONE. 2021;16:e0261536 pubmed 出版商 |
| Hwang S, Somatilaka B, White K, Mukhopadhyay S. Ciliary and extraciliary Gpr161 pools repress hedgehog signaling in a tissue-specific manner. elife. 2021;10: pubmed 出版商 |
| Martens Y, Xu S, Tait R, Li G, Zhao X, Lu W, et al. Generation and validation of APOE knockout human iPSC-derived cerebral organoids. STAR Protoc. 2021;2:100571 pubmed 出版商 |
| Gao X, Li G, Deng H, Feng W, Li Y, Liu M, et al. Generation of an iPSC line (GWCMCi002-A) from an X-linked Alport syndrome patient with a hemizygous splicing mutation (NM_000495.4, c. 1517-1 G > T) in the COL4A5 gene. Stem Cell Res. 2021;53:102388 pubmed 出版商 |
| Li J, Wu K, Guan J, Wang Q, Wang H. Generation of a human induced pluripotent stem cell line (CPGHi003-A) from an auditory neuropathy patient with AIFM1 p.R422Q mutation. Stem Cell Res. 2021;53:102376 pubmed 出版商 |
| Jia N, Gong X, Chen J, Yang T, Bao C, Shen J, et al. Generation of an induced pluripotent stem cell line (OGHFUi001-A) from a type 1 early infantile epileptic encephalopathy with ARX mutation. Stem Cell Res. 2021;53:102367 pubmed 出版商 |
| Yu Q, Biswas S, Ma G, Zhao P, Li B, Li J. Canonical NF-κB signaling maintains corneal epithelial integrity and prevents corneal aging via retinoic acid. elife. 2021;10: pubmed 出版商 |
| Nakashima H, Tsujimura K, Irie K, Imamura T, Trujillo C, Ishizu M, et al. MeCP2 controls neural stem cell fate specification through miR-199a-mediated inhibition of BMP-Smad signaling. Cell Rep. 2021;35:109124 pubmed 出版商 |
| Padmanabhan Nair V, Liu H, Ciceri G, Jungverdorben J, Frishman G, Tchieu J, et al. Activation of HERV-K(HML-2) disrupts cortical patterning and neuronal differentiation by increasing NTRK3. Cell Stem Cell. 2021;28:1566-1581.e8 pubmed 出版商 |
| Ramme A, Faust D, Koenig L, Nguyen N, Marx U. Generation of two additional integration-free iPSC lines from related human donors. Stem Cell Res. 2021;53:102327 pubmed 出版商 |
| Li N, Lin S, Li Y, Sun J, Zhang L, Chen M. An induced pluripotent stem cell line (GZHMCi004-A) derived from a fetus with heterozygous G380R mutation in FGFR3 gene causing achondroplasia. Stem Cell Res. 2021;53:102322 pubmed 出版商 |
| Ma L, Wu Z, Tang Q, Ji X, Mei Y, Peng T, et al. Generation of an induced pluripotent stem cell line from a patient with global development delay carrying DYRK1A mutation (c.1730T>A) and a gene correction isogenic iPSC line. Stem Cell Res. 2021;53:102305 pubmed 出版商 |
| Schinzel F, Seyfer H, Ebbers L, Nothwang H. The Lbx1 lineage differentially contributes to inhibitory cell types of the dorsal cochlear nucleus, a cerebellum-like structure, and the cerebellum. J Comp Neurol. 2021;529:3032-3045 pubmed 出版商 |
| Bannier Hélaouët M, Post Y, Korving J, Trani Bustos M, Gehart H, Begthel H, et al. Exploring the human lacrimal gland using organoids and single-cell sequencing. Cell Stem Cell. 2021;28:1221-1232.e7 pubmed 出版商 |
| Eze U, Bhaduri A, Haeussler M, Nowakowski T, Kriegstein A. Single-cell atlas of early human brain development highlights heterogeneity of human neuroepithelial cells and early radial glia. Nat Neurosci. 2021;24:584-594 pubmed 出版商 |
| Gao X, Qiu S, Wang W, Kang D, Su N, Dai P, et al. Generation of a gene corrected human isogenic iPSC line (CPGHi002-A-1) from a DDOD patient with heterozygous c.1516 C>T mutation in the ATP6V1B2 gene. Stem Cell Res. 2021;53:102271 pubmed 出版商 |
| Kweon H, Jung W, Im G, Ryoo J, Lee J, Do H, et al. Excitatory neuronal CHD8 in the regulation of neocortical development and sensory-motor behaviors. Cell Rep. 2021;34:108780 pubmed 出版商 |
| Sun X, Zhou X, Dong B, Wang C, Xiao X, Wang Y. Generation of a gene-corrected isogenic iPSC line (AHQUi001-A-1) from a patient with familial hypertriglyceridemia (FHTG) carrying a heterozygous p.C310R (c.928 T > C) mutation in LPL gene using CRISPR/Cas9. Stem Cell Res. 2021;52:102230 pubmed 出版商 |
| Merkert S, Wunderlich S, Beier J, Franke A, Schwanke K, Göhring G, et al. Generation of two iPSC clones (MHHi021-A and MHHi021-B) from a patient with hypertrophic cardiomyopathy with p.Arg723Gly mutation in the MYH7 gene. Stem Cell Res. 2021;52:102208 pubmed 出版商 |
| Schmid B, Holst B, Clausen C, Bahnassawy L, Reinhardt P, Bakker M, et al. Generation of a set of isogenic iPSC lines carrying all APOE genetic variants (Ɛ2/Ɛ3/Ɛ4) and knock-out for the study of APOE biology in health and disease. Stem Cell Res. 2021;52:102180 pubmed 出版商 |
| Kim T, Piao J, Koo S, Kriks S, Chung S, Betel D, et al. Biphasic Activation of WNT Signaling Facilitates the Derivation of Midbrain Dopamine Neurons from hESCs for Translational Use. Cell Stem Cell. 2021;28:343-355.e5 pubmed 出版商 |
| Haag D, Mack N, Benites Goncalves da Silva P, Statz B, Clark J, Tanabe K, et al. H3.3-K27M drives neural stem cell-specific gliomagenesis in a human iPSC-derived model. Cancer Cell. 2021;: pubmed 出版商 |
| Chen M, Lin S, Li N, Li Y, Li Y, Zhang L. An induced pluripotent stem cell line (GZHMCi003-A) derived from a fetus with exon 3 heterozygous deletion in RUNX2 gene causing cleidocranial dysplasia. Stem Cell Res. 2021;51:102166 pubmed 出版商 |
| Li M, Zhu L, Liu J, Huang H, Guo H, Wang L, et al. Loss of FOXC1 contributes to the corneal epithelial fate switch and pathogenesis. Signal Transduct Target Ther. 2021;6:5 pubmed 出版商 |
| Kim H, Lee S, Lim J, Yoo J, Hwang D. The epidermal growth factor receptor variant type III mutation frequently found in gliomas induces astrogenesis in human cerebral organoids. Cell Prolif. 2021;54:e12965 pubmed 出版商 |
| Chai G, Webb A, Li C, Antaki D, Lee S, Breuss M, et al. Mutations in Spliceosomal Genes PPIL1 and PRP17 Cause Neurodegenerative Pontocerebellar Hypoplasia with Microcephaly. Neuron. 2021;109:241-256.e9 pubmed 出版商 |
| Ahn L, Coatti G, Liu J, Gumus E, Schaffer A, Miranda H. An epilepsy-associated ACTL6B variant captures neuronal hyperexcitability in a human induced pluripotent stem cell model. J Neurosci Res. 2021;99:110-123 pubmed 出版商 |
| Ucuncu E, Rajamani K, Wilson M, Medina Cano D, Altin N, David P, et al. MINPP1 prevents intracellular accumulation of the chelator inositol hexakisphosphate and is mutated in Pontocerebellar Hypoplasia. Nat Commun. 2020;11:6087 pubmed 出版商 |
| de Leeuw V, van Oostrom C, Imholz S, Piersma A, Hessel E, Dollé M. Going Back and Forth: Episomal Vector Reprogramming of Peripheral Blood Mononuclear Cells to Induced Pluripotent Stem Cells and Subsequent Differentiation into Cardiomyocytes and Neuron-Astrocyte Co-cultures. Cell Reprogram. 2020;22:300-310 pubmed 出版商 |
| Li Z, Lang Y, Sakamuru S, Samrat S, Trudeau N, Kuo L, et al. Methylene blue is a potent and broad-spectrum inhibitor against Zika virus in vitro and in vivo. Emerg Microbes Infect. 2020;9:2404-2416 pubmed 出版商 |
| Yao H, Hannum D, Zhai Y, Hill S, Albanus R, Lou W, et al. CHD7 promotes neural progenitor differentiation in embryonic stem cells via altered chromatin accessibility and nascent gene expression. Sci Rep. 2020;10:17445 pubmed 出版商 |
| Jeong D, Lozano Casasbuenas D, Gengatharan A, Edwards K, Saghatelyan A, Kaplan D, et al. LRIG1-Mediated Inhibition of EGF Receptor Signaling Regulates Neural Precursor Cell Proliferation in the Neocortex. Cell Rep. 2020;33:108257 pubmed 出版商 |
| Gao X, Qiu S, Feng M, Huang S, Kang D, Han M, et al. Establishment of human induced pluripotent stem cell line (CPGHi002-A) from a 10-month-old female patient with DDOD syndrome carrying a heterozygous c.1516 C > T mutation in ATP6V1B2. Stem Cell Res. 2020;48:101986 pubmed 出版商 |
| Zhang L, Avery J, Yin A, Singh A, Cliff T, Yin H, et al. Generation of Functional Brown Adipocytes from Human Pluripotent Stem Cells via Progression through a Paraxial Mesoderm State. Cell Stem Cell. 2020;27:784-797.e11 pubmed 出版商 |
| Pereiro X, Miltner A, La Torre A, Vecino E. Effects of Adult Müller Cells and Their Conditioned Media on the Survival of Stem Cell-Derived Retinal Ganglion Cells. Cells. 2020;9: pubmed 出版商 |
| Somatilaka B, Hwang S, Palicharla V, White K, Badgandi H, Shelton J, et al. Ankmy2 Prevents Smoothened-Independent Hyperactivation of the Hedgehog Pathway via Cilia-Regulated Adenylyl Cyclase Signaling. Dev Cell. 2020;: pubmed 出版商 |
| Tsai M, Cheng H, Nian F, Liu C, Chao N, Chiang K, et al. Impairment in dynein-mediated nuclear translocation by BICD2 C-terminal truncation leads to neuronal migration defect and human brain malformation. Acta Neuropathol Commun. 2020;8:106 pubmed 出版商 |
| Yan P, Liu Z, Song M, Wu Z, Xu W, Li K, et al. Genome-wide R-loop Landscapes during Cell Differentiation and Reprogramming. Cell Rep. 2020;32:107870 pubmed 出版商 |
| Birkhoff J, Brouwer R, Kolovos P, Korporaal A, Bermejo Santos A, Boltsis I, et al. Targeted chromatin conformation analysis identifies novel distal neural enhancers of ZEB2 in pluripotent stem cell differentiation. Hum Mol Genet. 2020;29:2535-2550 pubmed 出版商 |
| Cederquist G, Tchieu J, Callahan S, Ramnarine K, Ryan S, Zhang C, et al. A Multiplex Human Pluripotent Stem Cell Platform Defines Molecular and Functional Subclasses of Autism-Related Genes. Cell Stem Cell. 2020;27:35-49.e6 pubmed 出版商 |
| Patmore D, Jassim A, Nathan E, Gilbertson R, Tahan D, Hoffmann N, et al. DDX3X Suppresses the Susceptibility of Hindbrain Lineages to Medulloblastoma. Dev Cell. 2020;54:455-470.e5 pubmed 出版商 |
| Quintana Urzainqui I, Hernández Malmierca P, Clegg J, Li Z, Kozic Z, Price D. The role of the diencephalon in the guidance of thalamocortical axons in mice. Development. 2020;147: pubmed 出版商 |
| Xiao D, Deng Q, Guo Y, Huang X, Zou M, Zhong J, et al. Generation of self-organized sensory ganglion organoids and retinal ganglion cells from fibroblasts. Sci Adv. 2020;6:eaaz5858 pubmed 出版商 |
| Gregory J, Hoelzli E, Abdelaal R, Braine C, Cuevas M, Halpern M, et al. Cell Type-Specific In Vitro Gene Expression Profiling of Stem Cell-Derived Neural Models. Cells. 2020;9: pubmed 出版商 |
| Roy A, Millen K, Kapur R. Hippocampal granule cell dispersion: a non-specific finding in pediatric patients with no history of seizures. Acta Neuropathol Commun. 2020;8:54 pubmed 出版商 |
| Selvadurai H, Luis E, Desai K, Lan X, Vladoiu M, Whitley O, et al. Medulloblastoma Arises from the Persistence of a Rare and Transient Sox2+ Granule Neuron Precursor. Cell Rep. 2020;31:107511 pubmed 出版商 |
| Mirjalili Mohanna S, Hickmott J, Lam S, Chiu N, Lengyell T, Tam B, et al. Germline CRISPR/Cas9-Mediated Gene Editing Prevents Vision Loss in a Novel Mouse Model of Aniridia. Mol Ther Methods Clin Dev. 2020;17:478-490 pubmed 出版商 |
| Popovitchenko T, Park Y, Page N, Luo X, Krsnik Z, Liu Y, et al. Translational derepression of Elavl4 isoforms at their alternative 5' UTRs determines neuronal development. Nat Commun. 2020;11:1674 pubmed 出版商 |
| Shao W, Yang J, He M, Yu X, Lee C, Yang Z, et al. Centrosome anchoring regulates progenitor properties and cortical formation. Nature. 2020;580:106-112 pubmed 出版商 |
| Plaza Reyes A, Petrus Reurer S, Padrell Sánchez S, Kumar P, Douagi I, Bartuma H, et al. Identification of cell surface markers and establishment of monolayer differentiation to retinal pigment epithelial cells. Nat Commun. 2020;11:1609 pubmed 出版商 |
| Fregeac J, Moriceau S, Poli A, Nguyen L, Oury F, Colleaux L. Loss of the neurodevelopmental disease-associated gene miR-146a impairs neural progenitor differentiation and causes learning and memory deficits. Mol Autism. 2020;11:22 pubmed 出版商 |
| Gao M, Lei X, Han F, He K, Jin S, Zhang Y, et al. Patient-Specific Retinal Organoids Recapitulate Disease Features of Late-Onset Retinitis Pigmentosa. Front Cell Dev Biol. 2020;8:128 pubmed 出版商 |
| Chui A, Zhang Q, Dai Q, Shi S. Oxidative stress regulates progenitor behavior and cortical neurogenesis. Development. 2020;147: pubmed 出版商 |
| Bosze B, Moon M, Kageyama R, Brown N. Simultaneous Requirements for Hes1 in Retinal Neurogenesis and Optic Cup-Stalk Boundary Maintenance. J Neurosci. 2020;40:1501-1513 pubmed 出版商 |
| Laan L, Klar J, Sobol M, Hoeber J, Shahsavani M, Kele M, et al. DNA methylation changes in Down syndrome derived neural iPSCs uncover co-dysregulation of ZNF and HOX3 families of transcription factors. Clin Epigenetics. 2020;12:9 pubmed 出版商 |
| Tomita H, Cornejo F, Aranda Pino B, Woodard C, Rioseco C, Neel B, et al. The Protein Tyrosine Phosphatase Receptor Delta Regulates Developmental Neurogenesis. Cell Rep. 2020;30:215-228.e5 pubmed 出版商 |
| Shafa M, Walsh T, Panchalingam K, Richardson T, Menendez L, Tian X, et al. Long-Term Stability and Differentiation Potential of Cryopreserved cGMP-Compliant Human Induced Pluripotent Stem Cells. Int J Mol Sci. 2019;21: pubmed 出版商 |
| Pandey P, Tomney A, Woon M, Uth N, Shafighi F, Ngabo I, et al. End-to-End Platform for Human Pluripotent Stem Cell Manufacturing. Int J Mol Sci. 2019;21: pubmed 出版商 |
| Panagiotakos G, Haveles C, Arjun A, Petrova R, Rana A, Portmann T, et al. Aberrant calcium channel splicing drives defects in cortical differentiation in Timothy syndrome. elife. 2019;8: pubmed 出版商 |
| Bendriem R, Singh S, Aleem A, Antonetti D, Ross M. Tight junction protein occludin regulates progenitor Self-Renewal and survival in developing cortex. elife. 2019;8: pubmed 出版商 |
| Ramme A, Faust D, Koenig L, Marx U. Generation of four integration-free iPSC lines from related human donors. Stem Cell Res. 2019;41:101615 pubmed 出版商 |
| Saito K, Okamoto M, Watanabe Y, Noguchi N, Nagasaka A, Nishina Y, et al. Dorsal-to-Ventral Cortical Expansion Is Physically Primed by Ventral Streaming of Early Embryonic Preplate Neurons. Cell Rep. 2019;29:1555-1567.e5 pubmed 出版商 |
| Wörsdörfer P, Dalda N, Kern A, Kruger S, Wagner N, Kwok C, et al. Generation of complex human organoid models including vascular networks by incorporation of mesodermal progenitor cells. Sci Rep. 2019;9:15663 pubmed 出版商 |
| Komabayashi Suzuki M, Yamanishi E, Watanabe C, Okamura M, Tabata H, Iwai R, et al. Spatiotemporally Dependent Vascularization Is Differently Utilized among Neural Progenitor Subtypes during Neocortical Development. Cell Rep. 2019;29:1113-1129.e5 pubmed 出版商 |
| Singer R, Arnés L, Cui Y, Wang J, Gao Y, Guney M, et al. The Long Noncoding RNA Paupar Modulates PAX6 Regulatory Activities to Promote Alpha Cell Development and Function. Cell Metab. 2019;30:1091-1106.e8 pubmed 出版商 |
| Mao X, An Q, Xi H, Yang X, Zhang X, Yuan S, et al. Single-Cell RNA Sequencing of hESC-Derived 3D Retinal Organoids Reveals Novel Genes Regulating RPC Commitment in Early Human Retinogenesis. Stem Cell Reports. 2019;13:747-760 pubmed 出版商 |
| Postel M, Karam A, Pezeron G, Schneider Maunoury S, Clement F. A multiscale mathematical model of cell dynamics during neurogenesis in the mouse cerebral cortex. BMC Bioinformatics. 2019;20:470 pubmed 出版商 |
| Peter C, Saito A, Hasegawa Y, Tanaka Y, Nagpal M, Perez G, et al. In vivo epigenetic editing of Sema6a promoter reverses transcallosal dysconnectivity caused by C11orf46/Arl14ep risk gene. Nat Commun. 2019;10:4112 pubmed 出版商 |
| Uzquiano A, Cifuentes Diaz C, Jabali A, Romero D, Houllier A, Dingli F, et al. Mutations in the Heterotopia Gene Eml1/EML1 Severely Disrupt the Formation of Primary Cilia. Cell Rep. 2019;28:1596-1611.e10 pubmed 出版商 |
| Gao F, Elliott N, Ho J, Sharp A, Shokhirev M, Hargreaves D. Heterozygous Mutations in SMARCA2 Reprogram the Enhancer Landscape by Global Retargeting of SMARCA4. Mol Cell. 2019;75:891-904.e7 pubmed 出版商 |
| Bonnefont J, Tiberi L, van den Ameele J, Potier D, Gaber Z, Lin X, et al. Cortical Neurogenesis Requires Bcl6-Mediated Transcriptional Repression of Multiple Self-Renewal-Promoting Extrinsic Pathways. Neuron. 2019;103:1096-1108.e4 pubmed 出版商 |
| Lee E, Kim N, Park J, Kang K, Kim W, Sim N, et al. Global Analysis of Intercellular Homeodomain Protein Transfer. Cell Rep. 2019;28:712-722.e3 pubmed 出版商 |
| Li L, Ruan X, Wen C, Chen P, Liu W, Zhu L, et al. The COMPASS Family Protein ASH2L Mediates Corticogenesis via Transcriptional Regulation of Wnt Signaling. Cell Rep. 2019;28:698-711.e5 pubmed 出版商 |
| Liu Z, Osipovitch M, Benraiss A, Huynh N, Foti R, Bates J, et al. Dysregulated Glial Differentiation in Schizophrenia May Be Relieved by Suppression of SMAD4- and REST-Dependent Signaling. Cell Rep. 2019;27:3832-3843.e6 pubmed 出版商 |
| Kawaue T, Shitamukai A, Nagasaka A, Tsunekawa Y, Shinoda T, Saito K, et al. Lzts1 controls both neuronal delamination and outer radial glial-like cell generation during mammalian cerebral development. Nat Commun. 2019;10:2780 pubmed 出版商 |
| Docampo Seara A, Lanoizelet M, Lagadec R, Mazan S, Candal E, Rodriguez M. Mitral cell development in the olfactory bulb of sharks: evidences of a conserved pattern of glutamatergic neurogenesis. Brain Struct Funct. 2019;: pubmed 出版商 |
| Moore D, Meays B, Madduri L, Shahjin F, Chand S, Niu M, et al. Downregulation of an Evolutionary Young miR-1290 in an iPSC-Derived Neural Stem Cell Model of Autism Spectrum Disorder. Stem Cells Int. 2019;2019:8710180 pubmed 出版商 |
| Alexander J, Guan J, Li B, Maliskova L, Song M, Shen Y, et al. Live-cell imaging reveals enhancer-dependent Sox2 transcription in the absence of enhancer proximity. elife. 2019;8: pubmed 出版商 |
| Wang H, Xiao Z, Zheng J, Wu J, Hu X, Yang X, et al. ZEB1 Represses Neural Differentiation and Cooperates with CTBP2 to Dynamically Regulate Cell Migration during Neocortex Development. Cell Rep. 2019;27:2335-2353.e6 pubmed 出版商 |
| Zurkirchen L, Varum S, Giger S, Klug A, Häusel J, Bossart R, et al. Yin Yang 1 sustains biosynthetic demands during brain development in a stage-specific manner. Nat Commun. 2019;10:2192 pubmed 出版商 |
| Lindsay C, Roth J, LeSavage B, Heilshorn S. Bioprinting of stem cell expansion lattices. Acta Biomater. 2019;: pubmed 出版商 |
| Roy A, Murphy R, Deng M, MacDonald J, Bammler T, Aldinger K, et al. PI3K-Yap activity drives cortical gyrification and hydrocephalus in mice. elife. 2019;8: pubmed 出版商 |
| Wang S, Min Z, Ji Q, Geng L, Su Y, Liu Z, et al. Rescue of premature aging defects in Cockayne syndrome stem cells by CRISPR/Cas9-mediated gene correction. Protein Cell. 2019;: pubmed 出版商 |
| Langer L, Ward J, Archer T. Tumor suppressor SMARCB1 suppresses super-enhancers to govern hESC lineage determination. elife. 2019;8: pubmed 出版商 |
| Wilson C, Spaeth J, Karp J, Stocks B, Hoopes E, Stein R, et al. B lymphocytes protect islet β cells in diabetes prone NOD mice treated with imatinib. JCI Insight. 2019;5: pubmed 出版商 |
| Bashford A, Subramanian V. Mice with a conditional deletion of Talpid3 (KIAA0586) - a model for Joubert syndrome. J Pathol. 2019;248:396-408 pubmed 出版商 |
| Ren X, Hu B, Song M, Ding Z, Dang Y, Liu Z, et al. Maintenance of Nucleolar Homeostasis by CBX4 Alleviates Senescence and Osteoarthritis. Cell Rep. 2019;26:3643-3656.e7 pubmed 出版商 |
| Alzu bi A, Clowry G. Expression of ventral telencephalon transcription factors ASCL1 and DLX2 in the early fetal human cerebral cortex. J Anat. 2019;235:555-568 pubmed 出版商 |
| Ooi J, Langley S, Xu X, Utami K, Sim B, Huang Y, et al. Unbiased Profiling of Isogenic Huntington Disease hPSC-Derived CNS and Peripheral Cells Reveals Strong Cell-Type Specificity of CAG Length Effects. Cell Rep. 2019;26:2494-2508.e7 pubmed 出版商 |
| Zhang X, Liu Z, Liu X, Wang S, Zhang Y, He X, et al. Telomere-dependent and telomere-independent roles of RAP1 in regulating human stem cell homeostasis. Protein Cell. 2019;: pubmed 出版商 |
| Klein T, Klug K, Henkel L, Kwok C, Edenhofer F, Klopocki E, et al. Generation of two induced pluripotent stem cell lines from skin fibroblasts of sisters carrying a c.1094C>A variation in the SCN10A gene potentially associated with small fiber neuropathy. Stem Cell Res. 2019;35:101396 pubmed 出版商 |
| Ward J, Stoyas C, Switonski P, Ichou F, Fan W, Collins B, et al. Metabolic and Organelle Morphology Defects in Mice and Human Patients Define Spinocerebellar Ataxia Type 7 as a Mitochondrial Disease. Cell Rep. 2019;26:1189-1202.e6 pubmed 出版商 |
| Chang C, Zanini M, Shirvani H, Cheng J, Yu H, Feng C, et al. Atoh1 Controls Primary Cilia Formation to Allow for SHH-Triggered Granule Neuron Progenitor Proliferation. Dev Cell. 2019;48:184-199.e5 pubmed 出版商 |
| Cheng S, Liu T, Hu Y, Xia Y, Hou J, Huang C, et al. Conditional Inactivation of Pen-2 in the Developing Neocortex Leads to Rapid Switch of Apical Progenitors to Basal Progenitors. J Neurosci. 2019;39:2195-2207 pubmed 出版商 |
| Wu Z, Makihara S, Yam P, Teo S, Renier N, Balekoglu N, et al. Long-Range Guidance of Spinal Commissural Axons by Netrin1 and Sonic Hedgehog from Midline Floor Plate Cells. Neuron. 2019;101:635-647.e4 pubmed 出版商 |
| Lim Y, Cho I, Shi X, Grinspan J, Cho G, Golden J. Arx Expression Suppresses Ventralization of the Developing Dorsal Forebrain. Sci Rep. 2019;9:226 pubmed 出版商 |
| Robson J, Remke M, Kool M, Julian E, Korshunov A, Pfister S, et al. Identification of CD24 as a marker of Patched1 deleted medulloblastoma-initiating neural progenitor cells. PLoS ONE. 2019;14:e0210665 pubmed 出版商 |
| Chen Y, Tristan C, Mallanna S, Ormanoglu P, Titus S, Simeonov A, et al. Chemically Defined Neural Conversion of Human Pluripotent Stem Cells. Methods Mol Biol. 2019;1919:59-72 pubmed 出版商 |
| Ding W, Wu Q, Sun L, Pan N, Wang X. Cenpj Regulates Cilia Disassembly and Neurogenesis in the Developing Mouse Cortex. J Neurosci. 2019;39:1994-2010 pubmed 出版商 |
| Shu P, Wu C, Liu W, Ruan X, Liu C, Hou L, et al. The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system. J Biol Chem. 2019;294:3444-3453 pubmed 出版商 |
| Xu D, Yao M, Wang Y, Yuan L, Hoeck J, Yu J, et al. MEKK3 coordinates with FBW7 to regulate WDR62 stability and neurogenesis. PLoS Biol. 2018;16:e2006613 pubmed 出版商 |
| Yin W, Satkunendran T, Mo R, Morrissy S, Zhang X, Huang E, et al. Dual Regulatory Functions of SUFU and Targetome of GLI2 in SHH Subgroup Medulloblastoma. Dev Cell. 2019;48:167-183.e5 pubmed 出版商 |
| Lavado A, Park J, Pare J, Finkelstein D, Pan H, Xu B, et al. The Hippo Pathway Prevents YAP/TAZ-Driven Hypertranscription and Controls Neural Progenitor Number. Dev Cell. 2018;47:576-591.e8 pubmed 出版商 |
| Diacou R, Zhao Y, Zheng D, Cvekl A, Liu W. Six3 and Six6 Are Jointly Required for the Maintenance of Multipotent Retinal Progenitors through Both Positive and Negative Regulation. Cell Rep. 2018;25:2510-2523.e4 pubmed 出版商 |
| Nowakowski T, Rani N, Golkaram M, Zhou H, Alvarado B, Huch K, et al. Regulation of cell-type-specific transcriptomes by microRNA networks during human brain development. Nat Neurosci. 2018;21:1784-1792 pubmed 出版商 |
| Tripathy R, Leca I, van Dijk T, Weiss J, van Bon B, Sergaki M, et al. Mutations in MAST1 Cause Mega-Corpus-Callosum Syndrome with Cerebellar Hypoplasia and Cortical Malformations. Neuron. 2018;100:1354-1368.e5 pubmed 出版商 |
| Shibata S, Hayashi R, Okubo T, Kudo Y, Katayama T, Ishikawa Y, et al. Selective Laminin-Directed Differentiation of Human Induced Pluripotent Stem Cells into Distinct Ocular Lineages. Cell Rep. 2018;25:1668-1679.e5 pubmed 出版商 |
| Cargnin F, Kwon J, Katzman S, Chen B, Lee J, Lee S. FOXG1 Orchestrates Neocortical Organization and Cortico-Cortical Connections. Neuron. 2018;100:1083-1096.e5 pubmed 出版商 |
| Klein T, Henkel L, Klug K, Kwok C, Klopocki E, Uceyler N. Generation of the human induced pluripotent stem cell line UKWNLi002-A from dermal fibroblasts of a woman with a heterozygous c.608 C>T (p.Thr203Met) mutation in exon 3 of the nerve growth factor gene potentially associated with hereditary sensory. Stem Cell Res. 2018;33:171-174 pubmed 出版商 |
| Kim Y, Khoshkhoo S, Frankowski J, Zhu B, Abbasi S, Lee S, et al. Chd2 Is Necessary for Neural Circuit Development and Long-Term Memory. Neuron. 2018;100:1180-1193.e6 pubmed 出版商 |
| Nazir F, Becker B, Brinkmalm A, Höglund K, Sandelius Å, Bergström P, et al. Expression and secretion of synaptic proteins during stem cell differentiation to cortical neurons. Neurochem Int. 2018;121:38-49 pubmed 出版商 |
| Omer Javed A, Li Y, Muffat J, Su K, Cohen M, Lungjangwa T, et al. Microcephaly Modeling of Kinetochore Mutation Reveals a Brain-Specific Phenotype. Cell Rep. 2018;25:368-382.e5 pubmed 出版商 |
| Bovio P, Franz H, Heidrich S, Rauleac T, Kilpert F, Manke T, et al. Differential Methylation of H3K79 Reveals DOT1L Target Genes and Function in the Cerebellum In Vivo. Mol Neurobiol. 2019;56:4273-4287 pubmed 出版商 |
| Kutsche L, Gysi D, Fallmann J, Lenk K, Petri R, Swiersy A, et al. Combined Experimental and System-Level Analyses Reveal the Complex Regulatory Network of miR-124 during Human Neurogenesis. Cell Syst. 2018;7:438-452.e8 pubmed 出版商 |
| Hickmott J, Gunawardane U, Jensen K, Korecki A, Simpson E. Epistasis between Pax6Sey and genetic background reinforces the value of defined hybrid mouse models for therapeutic trials. Gene Ther. 2018;25:524-537 pubmed 出版商 |
| Ibañez Rodriguez M, Galiana M, Rasmussen J, Freites C, Noctor S, Muñoz E. Differential response of pineal microglia to surgical versus pharmacological stimuli. J Comp Neurol. 2018;526:2462-2481 pubmed 出版商 |
| Zhang Y, Yang Y, Jiang M, Huang S, Zhang W, Al Alam D, et al. 3D Modeling of Esophageal Development using Human PSC-Derived Basal Progenitors Reveals a Critical Role for Notch Signaling. Cell Stem Cell. 2018;23:516-529.e5 pubmed 出版商 |
| Homman Ludiye J, Kwan W, de Souza M, Bourne J. Full: Ontogenesis and development of the nonhuman primate pulvinar. J Comp Neurol. 2018;526:2870-2883 pubmed 出版商 |
| Kurabayashi N, Tanaka A, Nguyen M, Sanada K. The LPA-LPA4 axis is required for establishment of bipolar morphology and radial migration of newborn cortical neurons. Development. 2018;145: pubmed 出版商 |
| Le Dreau G, Escalona R, Fueyo R, Herrera A, Martinez J, Usieto S, et al. E proteins sharpen neurogenesis by modulating proneural bHLH transcription factors' activity in an E-box-dependent manner. elife. 2018;7: pubmed 出版商 |
| Hasenpusch Theil K, West S, Kelman A, Kozic Z, Horrocks S, McMahon A, et al. Gli3 controls the onset of cortical neurogenesis by regulating the radial glial cell cycle through Cdk6 expression. Development. 2018;145: pubmed 出版商 |
| Tang Y, Xiong S, Yu P, Liu F, Cheng L. Direct Conversion of Mouse Fibroblasts into Neural Stem Cells by Chemical Cocktail Requires Stepwise Activation of Growth Factors and Nup210. Cell Rep. 2018;24:1355-1362.e3 pubmed 出版商 |
| Docampo Seara A, Lagadec R, Mazan S, Rodriguez M, Quintana Urzainqui I, Candal E. Study of pallial neurogenesis in shark embryos and the evolutionary origin of the subventricular zone. Brain Struct Funct. 2018;223:3593-3612 pubmed 出版商 |
| Miesfeld J, Moon M, Riesenberg A, Contreras A, Kovall R, Brown N. Rbpj direct regulation of Atoh7 transcription in the embryonic mouse retina. Sci Rep. 2018;8:10195 pubmed 出版商 |
| Nakano Y, Kelly M, Rehman A, Boger E, Morell R, Kelley M, et al. Defects in the Alternative Splicing-Dependent Regulation of REST Cause Deafness. Cell. 2018;174:536-548.e21 pubmed 出版商 |
| Watanabe Y, Kawaue T, Miyata T. Differentiating cells mechanically limit the interkinetic nuclear migration of progenitor cells to secure apical cytogenesis. Development. 2018;145: pubmed 出版商 |
| Dominguez Gonzalez B, Billion K, Rous S, Pavie B, Lange C, Goodchild R. Excess LINC complexes impair brain morphogenesis in a mouse model of recessive TOR1A disease. Hum Mol Genet. 2018;27:2154-2170 pubmed 出版商 |
| Baizabal J, Mistry M, Garcia M, Gómez N, Olukoya O, Tran D, et al. The Epigenetic State of PRDM16-Regulated Enhancers in Radial Glia Controls Cortical Neuron Position. Neuron. 2018;98:945-962.e8 pubmed 出版商 |
| Karzbrun E, Kshirsagar A, Cohen S, Hanna J, Reiner O. Human Brain Organoids on a Chip Reveal the Physics of Folding. Nat Phys. 2018;14:515-522 pubmed 出版商 |
| Chau K, Shannon M, Fame R, Fonseca E, Mullan H, Johnson M, et al. Downregulation of ribosome biogenesis during early forebrain development. elife. 2018;7: pubmed 出版商 |
| Dhumale P, Menon S, Chiang J, Püschel A. The loss of the kinases SadA and SadB results in early neuronal apoptosis and a reduced number of progenitors. PLoS ONE. 2018;13:e0196698 pubmed 出版商 |
| Shafa M, Yang F, Fellner T, Rao M, Baghbaderani B. Human-Induced Pluripotent Stem Cells Manufactured Using a Current Good Manufacturing Practice-Compliant Process Differentiate Into Clinically Relevant Cells From Three Germ Layers. Front Med (Lausanne). 2018;5:69 pubmed 出版商 |
| Ing Esteves S, Kostadinov D, Marocha J, Sing A, Joseph K, Laboulaye M, et al. Combinatorial Effects of Alpha- and Gamma-Protocadherins on Neuronal Survival and Dendritic Self-Avoidance. J Neurosci. 2018;38:2713-2729 pubmed 出版商 |
| Janssens S, Schotsaert M, Karnik R, Balasubramaniam V, Dejosez M, Meissner A, et al. Zika Virus Alters DNA Methylation of Neural Genes in an Organoid Model of the Developing Human Brain. mSystems. 2018;3: pubmed 出版商 |
| Tu J, Huo Z, Liu M, Wang D, Xu A, Zhou R, et al. Generation of human embryonic stem cell line with heterozygous RB1 deletion by CRIPSR/Cas9 nickase. Stem Cell Res. 2018;28:29-32 pubmed 出版商 |
| Ramanathan M, Majzoub K, Rao D, Neela P, Zarnegar B, Mondal S, et al. RNA-protein interaction detection in living cells. Nat Methods. 2018;15:207-212 pubmed 出版商 |
| Zahr S, Yang G, Kazan H, Borrett M, Yuzwa S, Voronova A, et al. A Translational Repression Complex in Developing Mammalian Neural Stem Cells that Regulates Neuronal Specification. Neuron. 2018;97:520-537.e6 pubmed 出版商 |
| Parween S, Varghese D, Ardah M, Prabakaran A, Mensah Brown E, Emerald B, et al. Higher O-GlcNAc Levels Are Associated with Defects in Progenitor Proliferation and Premature Neuronal Differentiation during in-Vitro Human Embryonic Cortical Neurogenesis. Front Cell Neurosci. 2017;11:415 pubmed 出版商 |
| Goodson N, Nahreini J, Randazzo G, Uruena A, Johnson J, Brzezinski J. Prdm13 is required for Ebf3+ amacrine cell formation in the retina. Dev Biol. 2018;434:149-163 pubmed 出版商 |
| Wu X, Dao Thi V, Huang Y, Billerbeck E, Saha D, Hoffmann H, et al. Intrinsic Immunity Shapes Viral Resistance of Stem Cells. Cell. 2018;172:423-438.e25 pubmed 出版商 |
| Hoshino A, Ratnapriya R, Brooks M, Chaitankar V, Wilken M, Zhang C, et al. Molecular Anatomy of the Developing Human Retina. Dev Cell. 2017;43:763-779.e4 pubmed 出版商 |
| Scior A, Buntru A, Arnsburg K, Ast A, Iburg M, Juenemann K, et al. Complete suppression of Htt fibrilization and disaggregation of Htt fibrils by a trimeric chaperone complex. EMBO J. 2018;37:282-299 pubmed 出版商 |
| Todd L, Suarez L, Quinn C, Fischer A. Retinoic Acid-Signaling Regulates the Proliferative and Neurogenic Capacity of Müller Glia-Derived Progenitor Cells in the Avian Retina. Stem Cells. 2018;36:392-405 pubmed 出版商 |
| Gillentine M, Yin J, Bajić A, Zhang P, Cummock S, Kim J, et al. Functional Consequences of CHRNA7 Copy-Number Alterations in Induced Pluripotent Stem Cells and Neural Progenitor Cells. Am J Hum Genet. 2017;101:874-887 pubmed 出版商 |
| Broix L, Asselin L, Silva C, Ivanova E, Tilly P, Gilet J, et al. Ciliogenesis and cell cycle alterations contribute to KIF2A-related malformations of cortical development. Hum Mol Genet. 2018;27:224-238 pubmed 出版商 |
| Liu J, Liu W, Yang L, Wu Q, Zhang H, Fang A, et al. The Primate-Specific Gene TMEM14B Marks Outer Radial Glia Cells and Promotes Cortical Expansion and Folding. Cell Stem Cell. 2017;21:635-649.e8 pubmed 出版商 |
| Ramzy A, Mojibian M, Kieffer T. Insulin-Deficient Mouse β-Cells Do Not Fully Maturebut Can Be Remedied Through Insulin Replacementby Islet Transplantation. Endocrinology. 2018;159:83-102 pubmed 出版商 |
| Remez L, Onishi A, Menuchin Lasowski Y, Biran A, Blackshaw S, Wahlin K, et al. Pax6 is essential for the generation of late-born retinal neurons and for inhibition of photoreceptor-fate during late stages of retinogenesis. Dev Biol. 2017;432:140-150 pubmed 出版商 |
| Palencia Campos A, Ullah A, Nevado J, Yildirim R, Unal E, Ciorraga M, et al. GLI1 inactivation is associated with developmental phenotypes overlapping with Ellis-van Creveld syndrome. Hum Mol Genet. 2017;26:4556-4571 pubmed 出版商 |
| Cliff T, Wu T, Boward B, Yin A, Yin H, Glushka J, et al. MYC Controls Human Pluripotent Stem Cell Fate Decisions through Regulation of Metabolic Flux. Cell Stem Cell. 2017;21:502-516.e9 pubmed 出版商 |
| Mills T, Eliseeva T, Bersie S, Randazzo G, Nahreini J, Park K, et al. Combinatorial regulation of a Blimp1 (Prdm1) enhancer in the mouse retina. PLoS ONE. 2017;12:e0176905 pubmed 出版商 |
| Forrest M, Zhang H, Moy W, McGowan H, Leites C, Dionisio L, et al. Open Chromatin Profiling in hiPSC-Derived Neurons Prioritizes Functional Noncoding Psychiatric Risk Variants and Highlights Neurodevelopmental Loci. Cell Stem Cell. 2017;21:305-318.e8 pubmed 出版商 |
| Zhu Y, Wang L, Yu H, Yin F, Wang Y, Liu H, et al. In situ generation of human brain organoids on a micropillar array. Lab Chip. 2017;17:2941-2950 pubmed 出版商 |
| Hu X, Chen G, Zhang S, Zheng J, Wu J, Bai Q, et al. Persistent Expression of VCAM1 in Radial Glial Cells Is Required for the Embryonic Origin of Postnatal Neural Stem Cells. Neuron. 2017;95:309-325.e6 pubmed 出版商 |
| Todd L, Palazzo I, Squires N, Mendonca N, Fischer A. BMP- and TGF?-signaling regulate the formation of Müller glia-derived progenitor cells in the avian retina. Glia. 2017;65:1640-1655 pubmed 出版商 |
| Sun D, Zhou X, Yu H, He X, Guo W, Xiong W, et al. Regulation of neural stem cell proliferation and differentiation by Kinesin family member 2a. PLoS ONE. 2017;12:e0179047 pubmed 出版商 |
| Wang Q, Yue W, Jiang Z, Xue T, Kang S, Bergles D, et al. Synergistic Signaling by Light and Acetylcholine in Mouse Iris Sphincter Muscle. Curr Biol. 2017;27:1791-1800.e5 pubmed 出版商 |
| Andres L, Blong I, Evans A, Rumachik N, Yamaguchi T, Pham N, et al. Chemical Modulation of Protein O-GlcNAcylation via OGT Inhibition Promotes Human Neural Cell Differentiation. ACS Chem Biol. 2017;12:2030-2039 pubmed 出版商 |
| Sano N, Shimogawa T, Sakaguchi H, Ioroi Y, Miyawaki Y, Morizane A, et al. Enhanced Axonal Extension of Subcortical Projection Neurons Isolated from Murine Embryonic Cortex using Neuropilin-1. Front Cell Neurosci. 2017;11:123 pubmed 出版商 |
| Beattie R, Postiglione M, Burnett L, Laukoter S, Streicher C, Pauler F, et al. Mosaic Analysis with Double Markers Reveals Distinct Sequential Functions of Lgl1 in Neural Stem Cells. Neuron. 2017;94:517-533.e3 pubmed 出版商 |
| Lu H, Tan Q, Rousseaux M, Wang W, Kim J, Richman R, et al. Disruption of the ATXN1-CIC complex causes a spectrum of neurobehavioral phenotypes in mice and humans. Nat Genet. 2017;49:527-536 pubmed 出版商 |
| Hayashi R, Ishikawa Y, Katori R, Sasamoto Y, Taniwaki Y, Takayanagi H, et al. Coordinated generation of multiple ocular-like cell lineages and fabrication of functional corneal epithelial cell sheets from human iPS cells. Nat Protoc. 2017;12:683-696 pubmed 出版商 |
| Miyashita H, Niwano H, Yoshida S, Hatou S, Inagaki E, Tsubota K, et al. Long-term homeostasis and wound healing in an in vitro epithelial stem cell niche model. Sci Rep. 2017;7:43557 pubmed 出版商 |
| Park K, Randazzo G, Jones K, Brzezinski J. Gsg1, Trnp1, and Tmem215 Mark Subpopulations of Bipolar Interneurons in the Mouse Retina. Invest Ophthalmol Vis Sci. 2017;58:1137-1150 pubmed 出版商 |
| Mochizuki T, Luo Y, Tsai H, Hagiwara A, Masai I. Cell division and cadherin-mediated adhesion regulate lens epithelial cell movement in zebrafish. Development. 2017;144:708-719 pubmed 出版商 |
| Subramanian L, Bershteyn M, Paredes M, Kriegstein A. Dynamic behaviour of human neuroepithelial cells in the developing forebrain. Nat Commun. 2017;8:14167 pubmed 出版商 |
| Ren R, Deng L, Xue Y, Suzuki K, Zhang W, Yu Y, et al. Visualization of aging-associated chromatin alterations with an engineered TALE system. Cell Res. 2017;27:483-504 pubmed 出版商 |
| Boland M, Nazor K, Tran H, Szucs A, Lynch C, Paredes R, et al. Molecular analyses of neurogenic defects in a human pluripotent stem cell model of fragile X syndrome. Brain. 2017;140:582-598 pubmed 出版商 |
| Gabriel E, Ramani A, Karow U, Gottardo M, Natarajan K, Gooi L, et al. Recent Zika Virus Isolates Induce Premature Differentiation of Neural Progenitors in Human Brain Organoids. Cell Stem Cell. 2017;20:397-406.e5 pubmed 出版商 |
| Lardelli R, Schaffer A, Eggens V, Zaki M, Grainger S, Sathe S, et al. Biallelic mutations in the 3' exonuclease TOE1 cause pontocerebellar hypoplasia and uncover a role in snRNA processing. Nat Genet. 2017;49:457-464 pubmed 出版商 |
| Breuss M, Nguyen T, Srivatsan A, Leca I, Tian G, Fritz T, et al. Uner Tan syndrome caused by a homozygous TUBB2B mutation affecting microtubule stability. Hum Mol Genet. 2017;26:258-269 pubmed 出版商 |
| Retallack H, Di Lullo E, Arias C, Knopp K, Laurie M, Sandoval Espinosa C, et al. Zika virus cell tropism in the developing human brain and inhibition by azithromycin. Proc Natl Acad Sci U S A. 2016;113:14408-14413 pubmed |
| Ibañez Rodriguez M, Noctor S, Muñoz E. Cellular Basis of Pineal Gland Development: Emerging Role of Microglia as Phenotype Regulator. PLoS ONE. 2016;11:e0167063 pubmed 出版商 |
| Damiani D, Goffinet A, ALBERTS A, Tissir F. Lack of Diaph3 relaxes the spindle checkpoint causing the loss of neural progenitors. Nat Commun. 2016;7:13509 pubmed 出版商 |
| Tao C, Zhang X. Retinal Proteoglycans Act as Cellular Receptors for Basement Membrane Assembly to Control Astrocyte Migration and Angiogenesis. Cell Rep. 2016;17:1832-1844 pubmed 出版商 |
| Pei S, Liu L, Zhong Z, Wang H, Lin S, Shang J. Risk of prenatal depression and stress treatment: alteration on serotonin system of offspring through exposure to Fluoxetine. Sci Rep. 2016;6:33822 pubmed 出版商 |
| Simonin Y, Loustalot F, Desmetz C, Foulongne V, Constant O, Fournier Wirth C, et al. Zika Virus Strains Potentially Display Different Infectious Profiles in Human Neural Cells. EBioMedicine. 2016;12:161-169 pubmed 出版商 |
| Tachibana N, Cantrup R, Dixit R, Touahri Y, Kaushik G, Zinyk D, et al. Pten Regulates Retinal Amacrine Cell Number by Modulating Akt, Tgf?, and Erk Signaling. J Neurosci. 2016;36:9454-71 pubmed 出版商 |
| Yeung J, Ha T, Swanson D, Goldowitz D. A Novel and Multivalent Role of Pax6 in Cerebellar Development. J Neurosci. 2016;36:9057-69 pubmed 出版商 |
| Wiley L, Burnight E, DeLuca A, Anfinson K, Cranston C, Kaalberg E, et al. cGMP production of patient-specific iPSCs and photoreceptor precursor cells to treat retinal degenerative blindness. Sci Rep. 2016;6:30742 pubmed 出版商 |
| Bonney S, Harrison Uy S, Mishra S, MacPherson A, Choe Y, Li D, et al. Diverse Functions of Retinoic Acid in Brain Vascular Development. J Neurosci. 2016;36:7786-801 pubmed 出版商 |
| Abdullah A, Zhang H, Nie Y, Tang W, Sun T. CDK7 and miR-210 Co-regulate Cell-Cycle Progression of Neural Progenitors in the Developing Neocortex. Stem Cell Reports. 2016;7:69-79 pubmed 出版商 |
| Tian E, Sun G, Sun G, Chao J, Ye P, Warden C, et al. Small-Molecule-Based Lineage Reprogramming Creates Functional Astrocytes. Cell Rep. 2016;16:781-92 pubmed 出版商 |
| Moura D, Fernández I, MarÃn Royo G, López Sánchez I, MartÃn Doncel E, Vega F, et al. Oncogenic Sox2 regulates and cooperates with VRK1 in cell cycle progression and differentiation. Sci Rep. 2016;6:28532 pubmed 出版商 |
| Plaisted W, Zavala A, Hingco E, Tran H, Coleman R, Lane T, et al. Remyelination Is Correlated with Regulatory T Cell Induction Following Human Embryoid Body-Derived Neural Precursor Cell Transplantation in a Viral Model of Multiple Sclerosis. PLoS ONE. 2016;11:e0157620 pubmed 出版商 |
| Cugola F, Fernandes I, Russo F, Freitas B, Dias J, Guimarães K, et al. The Brazilian Zika virus strain causes birth defects in experimental models. Nature. 2016;534:267-71 pubmed 出版商 |
| He S, Limi S, McGreal R, Xie Q, Brennan L, Kantorow W, et al. Chromatin remodeling enzyme Snf2h regulates embryonic lens differentiation and denucleation. Development. 2016;143:1937-47 pubmed 出版商 |
| Garreta E, de Oñate L, Fernández Santos M, Oria R, Tarantino C, Climent A, et al. Myocardial commitment from human pluripotent stem cells: Rapid production of human heart grafts. Biomaterials. 2016;98:64-78 pubmed 出版商 |
| Feng J, Xian Q, Guan T, Hu J, Wang M, Huang Y, et al. Celsr3 and Fzd3 Organize a Pioneer Neuron Scaffold to Steer Growing Thalamocortical Axons. Cereb Cortex. 2016;26:3323-34 pubmed 出版商 |
| Takeo Y, Kurabayashi N, Nguyen M, Sanada K. The G protein-coupled receptor GPR157 regulates neuronal differentiation of radial glial progenitors through the Gq-IP3 pathway. Sci Rep. 2016;6:25180 pubmed 出版商 |
| Paquet D, Kwart D, Chen A, Sproul A, Jacob S, Teo S, et al. Efficient introduction of specific homozygous and heterozygous mutations using CRISPR/Cas9. Nature. 2016;533:125-9 pubmed 出版商 |
| Okamoto M, Miyata T, Konno D, Ueda H, Kasukawa T, Hashimoto M, et al. Cell-cycle-independent transitions in temporal identity of mammalian neural progenitor cells. Nat Commun. 2016;7:11349 pubmed 出版商 |
| Xu J, Fan J, Wang X, Eacker S, Kam T, Chen L, et al. Cultured networks of excitatory projection neurons and inhibitory interneurons for studying human cortical neurotoxicity. Sci Transl Med. 2016;8:333ra48 pubmed 出版商 |
| Otani T, Marchetto M, Gage F, Simons B, Livesey F. 2D and 3D Stem Cell Models of Primate Cortical Development Identify Species-Specific Differences in Progenitor Behavior Contributing to Brain Size. Cell Stem Cell. 2016;18:467-80 pubmed 出版商 |
| Lin H, Ouyang H, Zhu J, Huang S, Liu Z, Chen S, et al. Lens regeneration using endogenous stem cells with gain of visual function. Nature. 2016;531:323-8 pubmed 出版商 |
| Wang W, Jossin Y, Chai G, Lien W, Tissir F, Goffinet A. Feedback regulation of apical progenitor fate by immature neurons through Wnt7-Celsr3-Fzd3 signalling. Nat Commun. 2016;7:10936 pubmed 出版商 |
| Sancho Martinez I, Nivet E, Xia Y, Hishida T, Aguirre A, Ocampo A, et al. Establishment of human iPSC-based models for the study and targeting of glioma initiating cells. Nat Commun. 2016;7:10743 pubmed 出版商 |
| Verheyen A, Diels A, Dijkmans J, Oyelami T, Meneghello G, Mertens L, et al. Using Human iPSC-Derived Neurons to Model TAU Aggregation. PLoS ONE. 2015;10:e0146127 pubmed 出版商 |
| Ahmad Z, Rafeeq M, Collombat P, Mansouri A. Pax6 Inactivation in the Adult Pancreas Reveals Ghrelin as Endocrine Cell Maturation Marker. PLoS ONE. 2015;10:e0144597 pubmed 出版商 |
| Delépine C, Meziane H, Nectoux J, Opitz M, Smith A, Ballatore C, et al. Altered microtubule dynamics and vesicular transport in mouse and human MeCP2-deficient astrocytes. Hum Mol Genet. 2016;25:146-57 pubmed 出版商 |
| Conrad E, Dai C, Spaeth J, Guo M, Cyphert H, Scoville D, et al. The MAFB transcription factor impacts islet α-cell function in rodents and represents a unique signature of primate islet β-cells. Am J Physiol Endocrinol Metab. 2016;310:E91-E102 pubmed 出版商 |
| Pataskar A, Jung J, Smialowski P, Noack F, Calegari F, Straub T, et al. NeuroD1 reprograms chromatin and transcription factor landscapes to induce the neuronal program. EMBO J. 2016;35:24-45 pubmed 出版商 |
| Martinez Cerdeno V, Camacho J, Fox E, Miller E, Ariza J, Kienzle D, et al. Prenatal Exposure to Autism-Specific Maternal Autoantibodies Alters Proliferation of Cortical Neural Precursor Cells, Enlarges Brain, and Increases Neuronal Size in Adult Animals. Cereb Cortex. 2016;26:374-383 pubmed 出版商 |
| Bando Y, Irie K, Shimomura T, Umeshima H, Kushida Y, Kengaku M, et al. Control of Spontaneous Ca2+ Transients Is Critical for Neuronal Maturation in the Developing Neocortex. Cereb Cortex. 2016;26:106-117 pubmed 出版商 |
