抗体

鸡多克隆抗体微管相关蛋白2(微管相关蛋白2)

C-1382-50

50微升

297美元

多克隆

鸡

未共轭

人类, 小鼠, 大鼠

免疫组化, 免疫细胞化学

鸡多克隆抗体微管相关蛋白2(微管相关蛋白2)

鸡

多克隆

纯化

50微升

297美元

17611279

IgY

Microtubules are 25nm diameter protein rods found in most kinds of eukarytic cells. They are polymerized from a dimeric subunit made of one a subunit and one b tubulin subunit. Microtubules are associated with a family of proteins called microtubule associated proteins (MAPs), which includes the protein t (tau) and a group of proteins referred to as MAP1, MAP2, MAP3, MAP4 and MAP5. MAP2 is made up of two ~280kDa apparent molecular weight bands referred to as MAP2a and MAP2b. A third lower molecular weight form, usually called MAP2c, corresponds to a pair of protein bands running at ~70kDa on SDS-PAGE gels. All these MAP2 forms are derived from a single gene by alternate transcription, and all share a C-terminal sequence which includes either three or four microtubule binding peptide sequences, which are very similar to those found in the related microtubule binding protein t (tau). MAP2 isoforms are expressed only in neuronal cells and specifically in the perikarya and dendrites of these cells. Antibodies to MAP2 are therefore excellent markers on neuronal cells, their perikarya and neuronal dendrites.

Hu, Rat, Ms, Bov

微管相关蛋白2;地图-2;微管相关蛋白2;

Bovine MAP2 isolated from brain by the GTP microtubule cycling method.

The specificity of this antibody has been confirmed by IC.

Small box at room temperature

Immunocytochemistry (IC) at suggested dilution of 1:2,500-5,000. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.

After reconstitution of lyophilised antibody, aliquot and store at -20°C for a higher stability. Avoid freeze-thaw cycles.

1. Dziennis S. et al (2007) Role of signal transducer and activator of transcription-3 in estradiol-mediated neuroprotection. J Neurosci. 2007 Jul 4;27(27):7268-74. .

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