产品简要
公司名称 :
Biosensis
产品类型 :
抗体
产品名称 :
Sheep antibody to Connexin-40 (253-269): whole serum
目录 :
S-063-100
规格 :
100微升
价格 :
297美元
克隆性 :
多克隆
宿主 :
共轭标签 :
nonconjugated
反应物种 :
大鼠
应用 :
免疫细胞化学
更多信息或购买 :
产品信息
目录代码 :
S-063-100
产品名称 :
Sheep antibody to Connexin-40 (253-269): whole serum
宿主物种 :
克隆性 :
多克隆
产品类型 :
Whole Serum
规格 :
100微升
标价 :
297美元
产品描述 :
FUNCTION: One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low molecular weight diffuse from one cell to a neighboring cell. SUBUNIT: A connexon is composed of a hexamer of connexins. SUBCELLULAR LOCATION: Membrane; multi-pass membrane protein. TISSUE SPECIFICITY: Highly expressed in lung. SIMILARITY: Belongs to the connexin family. Alpha-type (group II) subfamily.
交叉活性 :
This antiserum recognises Connexin-40 in rat.
别名 :
Gap junction alpha-5 protein; Cx40; Gja5; Cxn-40
免疫原 :
A synthetic peptide (SLVQGLTP PPDFNQCLK) as part of rat Connexin-40 protein (aa: 253-269) conjugated to diphtheria toxoid has been used as the immunogen.
特异性 :
Western blotting of cell membranes of COS cells transiently transfected with cDNA encoding Connexin-40 shows two bands of molecular weight 38 and 40 kDa which are abolished by preincubation with the immunising peptide. No such bands are detected in western blots of membranes from non-transfected cells or cells transfected with cDNA encoding Connexin-37, Connexin-43 or Connexin-45.
包装 :
Small box at room temperature
应用摘要 :
Immunofluorescence, Western blot. A dilution of 1:10,000 to 1: 50,000 is recommended for these applications. Biosensis recommends optimal dilutions/concentrations should be determined by the end user.
储存 :
After reconstitution keep aliquots at -20ºC for a higher stability, and at 4ºC with an appropriate antibacterial agent. Glycerol (1:1) may be added for an additional stability. Avoid repetitive freeze/thaw cycles.
产品编号 :
184
更多信息或购买 :
公司信息
Biosensis
39 Winwood Street, Thebarton, South Australia, 5031
info@biosensis.com
www.biosensis.com
61 8 83527711
公司总部: 澳大利亚
Biosensis specializes in antibodies, proteins, ELISA kits and Staining kits for Neuroscience, with particular emphasis on neurotrophins and neurotrophin receptors for which Biosensis has been the worldwide leader and OEM supplier for nearly 30 years. In addition to neurotrophins, our neuroscience portfolio includes products for research in neurodegenerative diseases, neurodevelopment, and neuro-metabolism. Areas of focus include Alzheimer's, Parkinson's and ALS diseases, as well as autophagy and metabolic and stress disorders including metabolic syndrome research, obesity, and neuroimmunology and inflammation.