产品简要
公司名称 :
Bioss
产品类型 :
抗体
产品名称 :
胱氨酸-天冬氨酸蛋白酶3多克隆抗体
目录 :
bs-0081R
规格 :
100微升
价格 :
289.5美元
克隆性 :
多克隆
宿主 :
共轭标签 :
未共轭
反应物种 :
山羊, 人类, 小鼠, 大鼠, , , ,
应用 :
免疫印迹, 酶联免疫吸附测定, 免疫细胞化学, 免疫组化-石蜡切片, 其他
更多信息或购买 :
文章摘录数: 61
出版应用/物种/样本/稀释参考文献
  • 免疫组化-石蜡切片; 大鼠
Kubatka P, Uramova S, Kello M, Kajo K, Kruzliak P, Mojzis J, et al. Antineoplastic effects of clove buds (Syzygium aromaticum L.) in the model of breast carcinoma. J Cell Mol Med. 2017;21:2837-2851 pubmed 出版商
  • 免疫印迹; 大鼠
Wang Y, Xuan L, Cui X, Wang Y, Chen S, Wei C, et al. Ibutilide treatment protects against ER stress induced apoptosis by regulating calumenin expression in tunicamycin treated cardiomyocytes. PLoS ONE. 2017;12:e0173469 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠
Abdel Hamid N, El Azab M, Moustafa Y. Macrolide antibiotics differentially influence human HepG2 cytotoxicity and modulate intrinsic/extrinsic apoptotic pathways in rat hepatocellular carcinoma model. Naunyn Schmiedebergs Arch Pharmacol. 2017;390:379-395 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠
Kubatka P, Kello M, Kajo K, Kruzliak P, Výbohová D, MojžiÅ¡ J, et al. Oregano demonstrates distinct tumour-suppressive effects in the breast carcinoma model. Eur J Nutr. 2017;56:1303-1316 pubmed 出版商
  • 免疫组化-石蜡切片; 兔
Košútová P, Mikolka P, Balentova S, Adamkov M, Kolomaznik M, Calkovska A, et al. Intravenous dexamethasone attenuated inflammation and influenced apoptosis of lung cells in an experimental model of acute lung injury. Physiol Res. 2016;65:S663-S672 pubmed
  • 免疫印迹; 猪
Zhao Y, Zhang W, Liu X, Zhang P, Hao Y, Li L, et al. Hydrogen Sulfide and/or Ammonia Reduces Spermatozoa Motility through AMPK/AKT Related Pathways. Sci Rep. 2016;6:37884 pubmed 出版商
  • 免疫组化-石蜡切片; 羊
  • 免疫印迹; 羊; 图 6e
Wang Y, Zhao Y, Yu S, Feng Y, Zhang H, Kou X, et al. Regulation of steroid hormones and energy status with cysteamine and its effect on spermatogenesis. Toxicol Appl Pharmacol. 2016;313:149-158 pubmed 出版商
  • 免疫细胞化学; 小鼠
Bozok Cetintaş V, Acikgoz E, Yigitturk G, Demir K, Oktem G, Tezcanli Kaymaz B, et al. Effects of flavopiridol on critical regulation pathways of CD133high/CD44high lung cancer stem cells. Medicine (Baltimore). 2016;95:e5150 pubmed
  • 免疫印迹; 人类
Yang J, Li G, Zhang K. Pro-survival effects by NF-?B, Akt and ERK(1/2) and anti-apoptosis actions by Six1 disrupt apoptotic functions of TRAIL-Dr4/5 pathway in ovarian cancer. Biomed Pharmacother. 2016;84:1078-1087 pubmed 出版商
  • 免疫印迹; 小鼠
Huang C, Liu H, Gong X, Wu L, Wen B. Expression of DNA methyltransferases and target microRNAs in human tissue samples related to sporadic colorectal cancer. Oncol Rep. 2016;36:2705-2714 pubmed 出版商
  • 免疫印迹; 大鼠
Yang J, Lu Y, Guo A. Platelet-rich plasma protects rat chondrocytes from interleukin-1?-induced apoptosis. Mol Med Rep. 2016;14:4075-4082 pubmed 出版商
  • 免疫印迹; 大鼠
Zhang X, Yu H. Matrine inhibits diethylnitrosamine-induced HCC proliferation in rats through inducing apoptosis via p53, Bax-dependent caspase-3 activation pathway and down-regulating MLCK overexpression. Iran J Pharm Res. 2016;15:491-9 pubmed
  • 免疫组化-石蜡切片; 小鼠
Chen Z, He N, Chen M, Zhao L, Li X. Tunable conjugation densities of camptothecin on hyaluronic acid for tumor targeting and reduction-triggered release. Acta Biomater. 2016;43:195-207 pubmed 出版商
  • 酶联免疫吸附测定; 人类
Zhao J, Qiu Y, Tian C, Fan T. The cytotoxic and pro-apoptotic effects of phenylephrine on corneal stromal cells via a mitochondrion-dependent pathway both in vitro and in vivo. Exp Toxicol Pathol. 2016;68:409-17 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠
Kassayová M, Bobrov N, Strojný L, Orendás P, Demečková V, Jendželovský R, et al. Anticancer and Immunomodulatory Effects of Lactobacillus plantarum LS/07, Inulin and Melatonin in NMU-induced Rat Model of Breast Cancer. Anticancer Res. 2016;36:2719-28 pubmed
  • 酶联免疫吸附测定; 人类
Shan M, Fan T. Cytotoxicity of carteolol to human corneal epithelial cells by inducing apoptosis via triggering the Bcl-2 family protein-mediated mitochondrial pro-apoptotic pathway. Toxicol In Vitro. 2016;35:36-42 pubmed 出版商
  • 免疫印迹; 人类
Gao H, Liu Y, Li K, Wu T, Peng J, Jing F. Hispidulin induces mitochondrial apoptosis in acute myeloid leukemia cells by targeting extracellular matrix metalloproteinase inducer. Am J Transl Res. 2016;8:1115-32 pubmed
  • 免疫印迹; 人类
Yoshinaga A, Kajiya N, Oishi K, Kamada Y, Ikeda A, Chigwechokha P, et al. NEU3 inhibitory effect of naringin suppresses cancer cell growth by attenuation of EGFR signaling through GM3 ganglioside accumulation. Eur J Pharmacol. 2016;782:21-9 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠
  • 免疫细胞化学; 大鼠
Lin C, Kuo Y, Chen T, Chien C. Quercetin-Rich Guava (Psidium guajava) Juice in Combination with Trehalose Reduces Autophagy, Apoptosis and Pyroptosis Formation in the Kidney and Pancreas of Type II Diabetic Rats. Molecules. 2016;21:334 pubmed 出版商
  • 免疫印迹; 小鼠; 1:200; 图 3
Liu Y, Su X, Hao J, Chen M, Liu W, Liao X, et al. Overexpression of PRL7D1 in Leydig Cells Causes Male Reproductive Dysfunction in Mice. Int J Mol Sci. 2016;17: pubmed 出版商
  • 免疫印迹; 人类
Qu Z, Zou X, Zhang X, Sheng J, Wang Y, Wang J, et al. Chelidonine induces mitotic slippage and apoptotic-like death in SGC-7901 human gastric carcinoma cells. Mol Med Rep. 2016;13:1336-44 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠
Kubatka P, Kapinová A, Kello M, Kruzliak P, Kajo K, Výbohová D, et al. Fruit peel polyphenols demonstrate substantial anti-tumour effects in the model of breast cancer. Eur J Nutr. 2016;55:955-65 pubmed 出版商
  • 免疫印迹; 大鼠
Lv R, Mao N, Wu J, Lu C, Ding M, Gu X, et al. Neuroprotective effect of allicin in a rat model of acute spinal cord injury. Life Sci. 2015;143:114-23 pubmed 出版商
  • 免疫印迹; 人类; 1:1000; 图 3
Song G, Li Y, Lin L, Cao Y. Anti-autophagic and anti-apoptotic effects of memantine in a SH-SY5Y cell model of Alzheimer's disease via mammalian target of rapamycin-dependent and -independent pathways. Mol Med Rep. 2015;12:7615-22 pubmed 出版商
  • 免疫印迹; 人类
Liu J, Che X, Chang S, Qiu G, He S, Fan L, et al. β-elemene enhances the radiosensitivity of gastric cancer cells by inhibiting Pak1 activation. World J Gastroenterol. 2015;21:9945-56 pubmed 出版商
  • 免疫印迹; 人类
Ding Q, Chen Y, Zhang Q, Guo Y, Huang Z, Dai L, et al. 8‑bromo‑7‑methoxychrysin induces apoptosis by regulating Akt/FOXO3a pathway in cisplatin‑sensitive and resistant ovarian cancer cells. Mol Med Rep. 2015;12:5100-8 pubmed 出版商
  • 免疫印迹; 大鼠
Han N, Yu L, Song Z, Luo L, Wu Y. Agmatine protects Müller cells from high-concentration glucose-induced cell damage via N-methyl-D-aspartic acid receptor inhibition. Mol Med Rep. 2015;12:1098-106 pubmed 出版商
  • 免疫印迹; 小鼠
Wang J, Lu M, Dai H, Zhang S, Wang H, Wei N. Esculetin, a coumarin derivative, exerts in vitro and in vivo antiproliferative activity against hepatocellular carcinoma by initiating a mitochondrial-dependent apoptosis pathway. Braz J Med Biol Res. 2015;48:245-53 pubmed 出版商
  • 免疫印迹; 人类
Fang C, Zhang J, Qi D, Fan X, Luo J, Liu L, et al. Evodiamine induces G2/M arrest and apoptosis via mitochondrial and endoplasmic reticulum pathways in H446 and H1688 human small-cell lung cancer cells. PLoS ONE. 2014;9:e115204 pubmed 出版商
  • 免疫印迹; 人类
Gao H, Jiang Q, Han Y, Peng J, Wang C. shRNA-mediated EMMPRIN silencing inhibits human leukemic monocyte lymphoma U937 cell proliferation and increases chemosensitivity to adriamycin. Cell Biochem Biophys. 2015;71:827-35 pubmed 出版商
  • 免疫印迹; 人类
Gao H, Jiang Q, Han Y, Peng J, Wang C. Hispidulin potentiates the antitumor effect of sunitinib against human renal cell carcinoma in laboratory models. Cell Biochem Biophys. 2015;71:757-64 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠
Luo X, Zhang H, Chen M, Wei J, Zhang Y, Li X. Antimetastasis and antitumor efficacy promoted by sequential release of vascular disrupting and chemotherapeutic agents from electrospun fibers. Int J Pharm. 2014;475:438-49 pubmed 出版商
  • 其他; 大鼠
Zhang B, Bian X, He P, Fu X, Higuchi K, Yang X, et al. The toxicity mechanisms of action of Aβ25-35 in isolated rat cardiac myocytes. Molecules. 2014;19:12242-57 pubmed 出版商
  • 免疫印迹; 人类
Yao K, Xing H, Yang W, Liao A, Wu B, Li Y, et al. Knockdown of RLIP76 expression by RNA interference inhibits proliferation, enhances apoptosis, and increases chemosensitivity to daunorubicin in U937 leukemia cells. Tumour Biol. 2014;35:8023-31 pubmed 出版商
  • 免疫印迹; 小鼠
Liu Y, Xue Q, Li X, Zhang J, Fu Z, Feng B, et al. Amelioration of stroke-induced neurological deficiency by lyophilized powder of catapol and puerarin. Int J Biol Sci. 2014;10:448-56 pubmed 出版商
  • 免疫印迹; 人类
Lin C, Wang L, Wang H, Fang S, Zhang Q, Yang L, et al. Lithocarpus polystachyus REHD leaf aqueous extract inhibits human breast cancer growth in vitro and in vivo. Nutr Cancer. 2014;66:613-24 pubmed 出版商
  • 免疫印迹; 人类
Ye B, Li J, Li Z, Yang J, Niu T, Wang S. Anti-tumor activity and relative mechanism of ethanolic extract of Marsdenia tenacissima (Asclepiadaceae) against human hematologic neoplasm in vitro and in vivo. J Ethnopharmacol. 2014;153:258-67 pubmed 出版商
  • 免疫印迹; 大鼠
Guan J, Li H, Lv T, Chen D, Yuan Y, Qu S. Bone morphogenetic protein-7 (BMP-7) mediates ischemic preconditioning-induced ischemic tolerance via attenuating apoptosis in rat brain. Biochem Biophys Res Commun. 2013;441:560-6 pubmed 出版商
  • 免疫印迹; 小鼠
Teng I, Chang Y, Wang L, Lu H, Wu L, Yang C, et al. Phospholipid-functionalized mesoporous silica nanocarriers for selective photodynamic therapy of cancer. Biomaterials. 2013;34:7462-70 pubmed 出版商
  • 免疫印迹; 山羊
Li M, Yu M, Liu C, Zhu H, He X, Peng S, et al. miR-34c works downstream of p53 leading to dairy goat male germline stem-cell (mGSCs) apoptosis. Cell Prolif. 2013;46:223-31 pubmed 出版商
  • 免疫组化-石蜡切片; 人类
Ma X, Lv P, Ye S, Zhang Y, Li S, Kan C, et al. DT390-triTMTP1, a novel fusion protein of diphtheria toxin with tandem repeat TMTP1 peptide, preferentially targets metastatic tumors. Mol Pharm. 2013;10:115-26 pubmed 出版商
  • 免疫细胞化学; 小鼠
Wei G, Chen Y, Chen D, Lai X, Liu D, Deng R, et al. ?-Asarone inhibits neuronal apoptosis via the CaMKII/CREB/Bcl-2 signaling pathway in an in vitro model and A?PP/PS1 mice. J Alzheimers Dis. 2013;33:863-80 pubmed 出版商
  • 免疫组化-石蜡切片; 大鼠
Wang G, Han B, Zhou H, Wu L, Wang Y, Jia G, et al. Inhibition of hydrogen sulfide synthesis provides protection for severe acute pancreatitis rats via apoptosis pathway. Apoptosis. 2013;18:28-42 pubmed 出版商
  • 免疫印迹; 牛
Rosenzweig D, Djap M, Ou S, Quinn T. Mechanical injury of bovine cartilage explants induces depth-dependent, transient changes in MAP kinase activity associated with apoptosis. Osteoarthritis Cartilage. 2012;20:1591-602 pubmed 出版商
  • 免疫组化-石蜡切片; 小鼠
  • 免疫印迹; 小鼠
Lei M, Bai X, Yang T, Lai X, Qiu W, Yang L, et al. Gsdma3 is a new factor needed for TNF-?-mediated apoptosis signal pathway in mouse skin keratinocytes. Histochem Cell Biol. 2012;138:385-96 pubmed 出版商
  • 免疫组化-石蜡切片; 猪
Sun Y, Zhang J, Ping Z, Wang C, Sun Y, Chen L, et al. Relationship between apoptosis and proliferation in granulosa and theca cells of cystic follicles in sows. Reprod Domest Anim. 2012;47:601-8 pubmed 出版商
Kuriakose T, Zheng M, Neale G, Kanneganti T. IRF1 Is a Transcriptional Regulator of ZBP1 Promoting NLRP3 Inflammasome Activation and Cell Death during Influenza Virus Infection. J Immunol. 2018;200:1489-1495 pubmed 出版商
He N, Chen Z, Yuan J, Zhao L, Chen M, Wang T, et al. Tumor pH-Responsive Release of Drug-Conjugated Micelles from Fiber Fragments for Intratumoral Chemotherapy. ACS Appl Mater Interfaces. 2017;9:32534-32544 pubmed 出版商
Ochigbo G, Saba A, Oyagbemi A, Omobowale T, Asenuga E. Polyphenol-rich fraction of Parquetina nigrescens mitigates dichlorvos-induced neurotoxicity and apoptosis. J Ayurveda Integr Med. 2017;8:27-36 pubmed 出版商
Clark A, Coury E, Meilhac A, Petty H. WO3/Pt nanoparticles are NADPH oxidase biomimetics that mimic effector cells in vitro and in vivo. Nanotechnology. 2016;27:065101 pubmed 出版商
Dong L, Wang H, Niu J, Zou M, Wu N, Yu D, et al. Echinacoside induces apoptotic cancer cell death by inhibiting the nucleotide pool sanitizing enzyme MTH1. Onco Targets Ther. 2015;8:3649-64 pubmed 出版商
Jia J, Dai S, Sun X, Sang Y, Xu Z, Zhang J, et al. A preliminary study of the effect of ECRG4 overexpression on the proliferation and apoptosis of human laryngeal cancer cells and the underlying mechanisms. Mol Med Rep. 2015;12:5058-64 pubmed 出版商
Tian A, Qin X, Wu A, Zhang H, Xu Q, Xing D, et al. Nanoscale TiO2 nanotubes govern the biological behavior of human glioma and osteosarcoma cells. Int J Nanomedicine. 2015;10:2423-39 pubmed 出版商
Xiao K, Zou W, Yang Z, Rehman Z, Ansari A, Yuan H, et al. The role of visfatin on the regulation of inflammation and apoptosis in the spleen of LPS-treated rats. Cell Tissue Res. 2015;359:605-618 pubmed 出版商
Pan B, Yang L, Wang J, Wang Y, Wang J, Zhou X, et al. C-Abl tyrosine kinase mediates neurotoxic prion peptide-induced neuronal apoptosis via regulating mitochondrial homeostasis. Mol Neurobiol. 2014;49:1102-16 pubmed 出版商
Sondag G, Salihoglu S, Lababidi S, Crowder D, Moussa F, Abdelmagid S, et al. Osteoactivin induces transdifferentiation of C2C12 myoblasts into osteoblasts. J Cell Physiol. 2014;229:955-66 pubmed 出版商
Li T, Pang S, Yu Y, Wu X, Guo J, Zhang S. Proliferation of parenchymal microglia is the main source of microgliosis after ischaemic stroke. Brain. 2013;136:3578-88 pubmed 出版商
Li M, Yu M, Liu C, Zhu H, Hua J. Expression of miR-34c in response to overexpression of Boule and Stra8 in dairy goat male germ line stem cells (mGSCs). Cell Biochem Funct. 2013;31:281-8 pubmed 出版商
Aksu I, Ates M, Baykara B, Kiray M, Sisman A, Buyuk E, et al. Anxiety correlates to decreased blood and prefrontal cortex IGF-1 levels in streptozotocin induced diabetes. Neurosci Lett. 2012;531:176-81 pubmed 出版商
Jiang J, Chen X, Chen X, Zheng S. Ginsenoside Rg3 inhibit hepatocellular carcinoma growth via intrinsic apoptotic pathway. World J Gastroenterol. 2011;17:3605-13 pubmed 出版商
Hu H, Kang J, Chen R, Mamuti W, Wu G, Yuan W. Drug-induced apoptosis of Echinococcus granulosus protoscoleces. Parasitol Res. 2011;109:453-9 pubmed 出版商
产品信息
SKU号 :
bs-0081R
名称 :
胱氨酸-天冬氨酸蛋白酶3多克隆抗体
类别 :
一抗
共轭 :
未共轭
宿主 :
靶蛋白 :
胱氨酸-天冬氨酸蛋白酶3
修饰 :
Unmodified
克隆性 :
多克隆
抗体亚型 :
IgG
浓度 :
1微克/微升
public immunogen range :
60-100/277
subcellular locations :
细胞质
来源 :
KLH合成多肽共轭人胱氨酸-天冬氨酸蛋白酶3(活性的)
基因编号链接 :
Entrez Gene: 836
Swiss Prot数据库 :
P42574
Swiss Prot数据库链接 :
Swiss Prot: P42574
应用 :
免疫印迹, 免疫组化-P, IF(免疫组化-P), IF(免疫细胞化学)
applications with dilutions :
免疫印迹(1:100-1000), 免疫组化-P(1:100-500), IF(免疫组化-P)(1:50-200), IF(免疫细胞化学)(1:50-200)
cross reactive species :
人类, 小鼠, 大鼠, 牛, 山羊
规格 :
100微升
价格 :
289.5美元
背景 :
Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly(ADP-ribose) polymerase (PARP) at a '216-Asp- -Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.
纯化 :
Purified by Protein A.
储存 :
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
同义词 :
CPP32; SCA-1; CPP32B; Caspase-3; CASP-3; Apopain; Cysteine protease CPP32; CPP-32; Protein Yama; SREBP cleavage activity 1; CASP3
铅时间 :
3 to 5 business days.
更多信息或购买 :
公司信息
Bioss
500 West Cummings Park
Suite 6500
Woburn, MA 01801
info@biossusa.com
http://biossusa.com
010-88798567
公司总部: 美国
Bioss Inc is a leading antibody developer and manufacturer with state of the art technologies. We have developed over 11,000 antigens/primary antibodies and more than 130,000 derived products including fluorochrome conjugated antibodies. In addition to reliable loading control and tag antibodies, our catalog includes over 1000 specific antibodies recognizing proteins with phosphorylation, acetylation, or methylation modifications. Our company promises fast delivery with strong, top quality scientific support. Bioss Inc is located in the greater Boston area of Massachusetts, the center of the world's largest and fastest growing biotech community.