产品简要
公司名称 :
Bioss
产品类型 :
抗体
产品名称 :
AKT1/2/3(Ser472/Ser473/Ser474)抗体
目录 :
bs-0876R
规格 :
100微升
价格 :
309.5美元
克隆性 :
多克隆
宿主 :
兔
共轭标签 :
nonconjugated
反应物种 :
人类, 小鼠, 大鼠
应用 :
免疫印迹, 免疫细胞化学, 免疫组化-石蜡切片
更多信息或购买 :
Bioss 产品网页
文章摘录数: 2
出版应用/物种/样品/稀释参考文献
  • 免疫印迹; 大鼠; 1:500; 图 5
Li G, Jia J, Ji K, Gong X, Wang R, Zhang X, et al. The neutrophil elastase inhibitor, sivelestat, attenuates sepsis-related kidney injury in rats. Int J Mol Med. 2016;38:767-75 pubmed 出版商
  • 免疫印迹; 人类; 1:10,000; 图 4c
Santos J, Mesquita D, Barros Silva J, Jerónimo C, Henrique R, Morais A, et al. Uncovering potential downstream targets of oncogenic GRPR overexpression in prostate carcinomas harboring ETS rearrangements. Oncoscience. 2015;2:497-507 pubmed
产品信息
SKU号 :
bs-0876R
名称 :
AKT1/2/3(Ser472/Ser473/Ser474)抗体
类别 :
一抗
共轭 :
未共轭
宿主 :
兔
靶蛋白 :
AKT1/2/3(Ser472/Ser473/Ser474)
修饰 :
磷酸化
修饰位点 :
Ser473
克隆性 :
多克隆
抗体亚型 :
IgG
浓度 :
1微克/微升
public immunogen range :
450-480/480
subcellular locations :
Cytoplasm, Nucleus
来源 :
KLH conjugated synthetic phosphopeptide derived from human AKT1 around the phosphorylation site of Ser473
基因编号链接 :
Entrez Gene: 24185
Swiss Prot数据库 :
P47196
Swiss Prot数据库链接 :
Swiss Prot: P47196
应用 :
免疫印迹, 免疫组化-P, IF(免疫组化-P)
applications with dilutions :
免疫印迹(1:100-1000), 免疫组化-P(1:100-500), IF(免疫组化-P)(1:50-200)
cross reactive species :
人类, 小鼠, 大鼠
规格 :
100微升
价格 :
309.5美元
背景 :
AKT1-specific substrates have been recently identified, including palladin (PALLD), which phosphorylation modulates cytoskeletal organization and cell motility; prohibitin (PHB), playing an important role in cell metabolism and proliferation; and CDKN1A, for which phosphorylation at 'Thr-145' induces its release from CDK2 and cytoplasmic relocalization. These recent findings indicate that the AKT1 isoform has a more specific role in cell motility and proliferation. Phosphorylates CLK2 thereby controlling cell survival to ionizing radiation.
纯化 :
Purified by Protein A.
储存 :
Aqueous buffered solution containing 1% BSA, 50% glycerol and 0.09% sodium azide. Store at -20°C for 12 months.
同义词 :
Akt; RAC-alpha serine/threonine-protein kinase; Protein kinase B; PKB; Protein kinase B alpha; PKB alpha; RAC-PK-alpha; Akt1
铅时间 :
3 to 5 business days.
更多信息或购买 :
Bioss 产品网页
公司信息
Bioss
500 West Cummings Park
Suite 6500
Woburn, MA 01801
info@biossusa.com
biossusa.com
010-88798567
公司总部: 美国
Bioss Inc is a leading antibody developer and manufacturer with state of the art technologies. We have developed over 11,000 antigens/primary antibodies and more than 130,000 derived products including fluorochrome conjugated antibodies. In addition to reliable loading control and tag antibodies, our catalog includes over 1000 specific antibodies recognizing proteins with phosphorylation, acetylation, or methylation modifications. Our company promises fast delivery with strong, top quality scientific support. Bioss Inc is located in the greater Boston area of Massachusetts, the center of the world's largest and fastest growing biotech community.