产品简要
公司名称 :
Bon Opus Biosciences
产品类型 :
抗体
产品名称 :
小鼠单克隆抗体抗人类肿瘤坏死因子α(TNF-α), 克隆C5G7
目录 :
BA010090
规格 :
0.5毫克
价格 :
378.00美元
克隆性 :
单克隆
宿主 :
小鼠
共轭标签 :
nonconjugated
克隆名称 :
C5G7
反应物种 :
人类
应用 :
酶联免疫吸附测定
更多信息或购买 :
产品信息
目录代码 :
BA010090
产品名称 :
小鼠单克隆抗体抗人类肿瘤坏死因子α(TNF-α), 克隆C5G7
产品类型 :
单克隆抗体
宿主物种 :
小鼠
克隆性 :
单克隆
克隆名称 :
C5G7
抗体亚型 :
IgG1, k
规格 :
0.5毫克
标价 :
378.00美元
登录号 :
P01375
产品描述 :
小鼠单克隆抗体人类肿瘤坏死因子α(TNF-α)
物种摘要 :
Human, other species not tested
背景 :
Tumor Necrosis Factor-alpha (TNF-α) is a multifunctional pro-inflammatory cytokine, mainly secreted by activated macrophages. TNF-α was named for its remarkable ability to cause hemorrhagic necrosis to tumors in mice. It is implicated with a variety of biological procedures including systemic inflammation, cell proliferation, apoptosis, lipid metabolism, and coagulation. The pleiotropic attribute of TNF-α regulation is associated with its ability to trigger multiple signalling pathways simultaneously. It is well documented that TNF-α functions through its receptors, TNFR1 (p55) and TNFR2 (p75). TNF-α not only contributes to the immune response to bacterial, fungal, viral and parasitic invasions, but also functions in tissue remodeling, autoimmune-diseases and the necrosis of specific tumors. TNF-α hyper-expression in response to some bacterial components such as LPS can cause life threatening septic shock. Recombinant TNF-α, in combination with chemotherapy, has been applied for treatment of soft sarcomas, melanomas and other irresectable tumors. Anti-TNF-α therapy has been used for treatment of rheumatoid arthritis.
免疫原 :
纯化重组人类TNF-α
特异性 :
这抗体反应对象人类TNF-α
缓冲液 :
冻干来自a溶液在0.01M PBS, pH值7.0
应用摘要 :
ELISA:反应对象TNF-α。 免疫印迹
储存 :
存放在-20°C
更多信息或购买 :
公司信息
Bon Opus Biosciences
86 Summit Ave
Suite LL300B
Summit, NJ 07901
orders@bonopusbio.com
www.bonopusbio.com
1-800-943-6396
公司总部: 美国