抗体

CD80/B7-1小鼠单克隆抗体IgG2b

BA110164

100微升

279美元

单克隆

小鼠

未共轭

8-E5

人类, 小鼠

免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪

抗体

CD80/B7-1小鼠单克隆抗体IgG2b

BA110164-100µl

279美元

100微升

多肽

免疫印迹, 免疫细胞化学, 免疫组化, FC

T-lymphocyte activation antigen CD80,Activation B7-1 antigen,BB1,CTLA-4 counter-receptor B7.1,CD_antigen: CD80

CD80/B7-1 is a molecule found on activated B cells and monocytes which provides a costimulatory signal necessary for T cell activation and survival. After engagement of T-cell receptor with antigen in association with major histocompatibility complex class II, a second signal mediated through the binding of B7 to CD28 greatly upregulates the production of multiple lymphokines. B7-1 is a costimulatory molecule for the activation of both CD4+ and CD8+ T lymphocytes that prevents the induction of clonal anergy. Thus, the transfer of B7-1 genes into tumor cells can induce protective immunity and lead to tumor rejection of some tumors in model systems of in vivo tumor growth.(M1007-10)

单克隆

8-E5

P33681

ProA affinity purified

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

小鼠

人类, 小鼠