抗体

cMet Rabbit polyclonal Antibody IgG

BA110185

100微升

279美元

多克隆

domestic rabbit

未共轭

人类, 小鼠, 大鼠

免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪

抗体

cMet Rabbit polyclonal Antibody IgG

BA110185-100µl

279美元

100微升

多肽

免疫印迹, 免疫细胞化学, 免疫组化, FC

肝细胞生长因子受体, HGF/SF受体, 原癌基因c met原癌基因, 分散因子受体, 酪氨酸蛋白激酶met原癌基因

c-Met (MET or MNNG HOS Transforming gene) is a proto-oncogene that encodes a protein known as hepatocyte growth factor receptor (HGFR). MET is a membrane receptor that is essential for embryonic development and wound healing. Hepatocyte growth factor (HGF) is the only known ligand of the MET receptor. MET is normally expressed by cells of epithelial origin, while expression of HGF is restricted to cells of mesenchymal origin. Upon HGF stimulation, MET induces several biological responses that collectively give rise to a program known as invasive growth. Abnormal MET activation in cancer correlates with poor prognosis, where aberrantly active MET triggers tumor growth, formation of new blood vessels (angiogenesis) that supply the tumor with nutrients, and cancer spread to other organs (metastasis). MET is deregulated in many types of human malignancies, including cancers of kidney, liver, stomach, breast, and brain.(ER40501)

多克隆

P16056

肽亲和纯化

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

兔

人类, 小鼠, 大鼠