抗体

EP-CAM小鼠单克隆抗体IgM

BA110254

100微升

279美元

单克隆

小鼠

未共轭

3-E1-E2

人类, 小鼠

免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪

抗体

EP-CAM小鼠单克隆抗体IgM

BA110254-100µl

279美元

100微升

重组蛋白

免疫印迹, 免疫细胞化学, 免疫组化, FC

Epithelial cell adhesion molecule,Adenocarcinoma-associated antigen,Cell surface glycoprotein Trop-1,Epithelial cell surface antigen,Epithelial glycoprotein,Epithelial glycoprotein 314,KS 1/4 antigen,KSA,Major gastrointestinal tumor-associated protein GA733-2,Tumor-associated calcium signal transducer 1,CD_antigen: CD326

Epithelial cell adhesion molecule (EpCAM) is a transmembrane glycoprotein mediating Ca2+-independent homotypic cell-cell adhesion in epithelia. EpCAM is also involved in cell signaling, migration, proliferation, and differentiation. Additionally, EpCAM has oncogenic potential via its capacity to upregulate c-myc, e-fabp, and cyclins A E. Since EpCAM is expressed exclusively in epithelia and epithelial-derived neoplasms, EpCAM can be used as diagnostic marker for various cancers. It appears to play a role in tumorigenesis and metastasis of carcinomas, so it can also act as a potential prognostic marker and as a potential target for immunotherapeutic strategies. Mutations in EpCAM have also been associated with congenital tufting enteropathy which causes intractable diarrhea in newborn children. Specificity/Source: This antibody is produced by immunizing mice with recombinant protein corresponding to a region of EpCAM.(EM1111)

单克隆

3-E1-E2

P16422

ProL affinity purified

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

小鼠

人类, 小鼠