抗体

ERK2小鼠单克隆抗体IgG1

BA110260

100微升

279美元

单克隆

小鼠

未共轭

5-D2

人类, 小鼠, 大鼠

免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪

抗体

ERK2小鼠单克隆抗体IgG1

BA110260-100µl

279美元

100微升

This antibody is produced by immunizing mice with Recombinant protein of ERK2.

免疫印迹, 免疫细胞化学, 免疫组化, FC

Mitogen-activated protein kinase 1,ERT1,Extracellular signal-regulated kinase 2,MAP kinase isoform p42,Mitogen-activated protein kinase 2

Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. MAPK1/ERK2 and MAPK3/ERK1 are the 2 MAPKs which play an important role in the MAPK/ERK cascade. They participate also in a signaling cascade initiated by activated KIT and KITLG/SCF. Depending on the cellular context, the MAPK/ERK cascade mediates diverse biological functions such as cell growth, adhesion, survival and differentiation through the regulation of transcription, translation, cytoskeletal rearrangements. The MAPK/ERK cascade plays also a role in initiation and regulation of meiosis, mitosis, and postmitotic functions in differentiated cells by phosphorylating a number of transcription factors. Moreover, the MAPK/ERK cascade is also involved in the regulation of the endosomal dynamics, including lysosome processing and endosome cycling through the perinuclear recycling compartment (PNRC); as well as in the fragmentation of the Golgi apparatus during mitosis.(M1407-3)

单克隆

5-D2

P28482

ProA affinity purified

1*TBS (pH7.4), 1%BSA, 40%Glycerol. Preservative: 0.05% Sodium Azide.

小鼠

人类, 小鼠, 大鼠