抗体

AFP兔多克隆抗体IgG

BA110837

100微升

279美元

多克隆

domestic rabbit

未共轭

人类, 小鼠, 大鼠

免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪

抗体

AFP兔多克隆抗体IgG

BA110837-100µl

279美元

100微升

重组蛋白

免疫印迹, 免疫细胞化学, 免疫组化, FC

Alpha-fetoprotein, Alpha-1-fetoprotein,Alpha-fetoglobulin

α-fetoprotein (AFP) is expressed in fetal liver at varying levels throughout development and is present only in trace amounts in normal adult tissues. AFP can be detected at abnormally high concentrations in hepatocellular carcinomas as well as in the plasma and ascitic fluid of adults with hepatoma. High AFP concentrations have been correlated with tumor cell growth, indicating that AFP can serve as a tumor marker. AFP binds copper, nickel and fatty acids, and in some cases may bind serum albumin or estrogen. It has been demonstrated that the AFP promoter is a target for NF-1 (nuclear factor-1), HNF-1 (hepatocyte nuclear factor-1) and C/EBP transcription factors. While HNF-1 binding to the AFP promoter results in AFP expression, NF-1 binding results in a decrease in AFP promoter activity.(R1601-1)

多克隆

P02771(人类)P02772(小鼠)P02773(大鼠)

ProA affinity purified

1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.

兔

人类, 小鼠, 大鼠