抗体

趋化因子受体4兔多克隆抗体IgG

BA111038

100微升

279美元

多克隆

domestic rabbit

未共轭

人类, 大鼠

免疫印迹, 免疫组化, 免疫细胞化学, 流式细胞仪

抗体

趋化因子受体4兔多克隆抗体IgG

BA111038-100µl

279美元

100微升

多肽

免疫印迹, 免疫细胞化学, 免疫组化, FC

C-X-C chemokine receptor type 4, FB22, Fusin, HM89, LCR1, Leukocyte-derived seven transmembrane domain receptor, Lipopolysaccharide-associated protein 3, NPYRL, Stromal cell-derived factor 1 receptor, CD_antigen: CD184

The C-X-C or a chemokine family is characterized by a pair of cysteine residues separated by a single amino acid and primarily functions as chemoattractants for neutrophils. The C-X-C family includes IL-8, NAP-2, MSGA and stromal cell derived factor-1 (SDF-1). SDF-1 was originally described as a pre-B cell stimulatory factor, but has now been shown to function as a potent chemo-attractant for T cells and monocytes but not neutrophils. Receptors for the C-X-C family are G protein-coupled, seven pass transmembrane domain proteins which include IL-8RA, IL-8RB and CXCR-4 (also known as LESTR or fusin). CXCR-4 is highly homologous to the IL-8 receptors, sharing 37% sequence identity at the amino acid level. The IL-8 receptors bind to IL-8, NAP-2 and MSGA, while fusin binds to its cognate ligand, SDF-1. CXCR-4 has been identified as the major co-receptor for T-tropic HIV-1 and SDF-1 has been shown to inhibit HIV-1 infection.(ER1802-28)

多克隆

P61073(人类)O08565(大鼠)

肽亲和纯化

1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.

兔

人类, 大鼠