抗体

磷脂酰肌醇(-3)激酶p85亚单位甲小鼠单克隆抗体IgG1

BA111059

100微升

279美元

单克隆

小鼠

未共轭

L3-D6

人类, 小鼠, 大鼠

免疫印迹, 免疫组化, 免疫细胞化学

抗体

磷脂酰肌醇(-3)激酶p85亚单位甲小鼠单克隆抗体IgG1

BA111059-100µl

279美元

100微升

Recombinant protein within human PI3-kinase p85 subunit alpha aa 1-200.

免疫印迹, 免疫组化, 免疫细胞化学

Phosphatidylinositol 3-kinase regulatory subunit alpha, Phosphatidylinositol 3-kinase 85 kDa regulatory subunit alpha

Phosphatidylinositol 3-kinase (PI 3-kinase) is composed of p85 and p110 subunits. p85 lacks PI 3-kinase activity and acts as an adapter, coupling p110 to activated protein tyrosine kinase. Two forms of p85 have been described (p85α and p85β), each possessing one SH3 and two SH2 domains. Various p110 isoforms have been identified. p110α and p110β interact with p85α, and p110α has also been shown to interact with p85β in vitro. p110δ expression is restricted to white blood cells. It has been shown to bind p85α and β, but it apparently does not phosphorylate these subunits. p110δ seems to have the capacity to autophosphorylate. p110γ does not interact with the p85 subunits. It has been shown to be activated by α and βγ heterotrimeric G proteins.(EM1701-62)

单克隆

L3-D6

P27986(人类)Q63787(大鼠)

ProG affinity purified.

1*TBS (pH7.4), 0.5%BSA, 50%Glycerol. Preservative: 0.05% Sodium Azide.

小鼠

人类, 小鼠, 大鼠